75 research outputs found
Enzyme-powered hollow mesoporous Janus nanomotors
The development of synthetic nanomotors for technological applications in particular for life science and nanomedicine is a key focus of current basic research. However, it has been challenging to make active nanosystems based on biocompatible materials consuming nontoxic fuels for providing self-propulsion. Here, we fabricate self-propelled Janus nanomotors based on hollow mesoporous silica nanoparticles (HMSNPs), which are powered by biocatalytic reactions of three different enzymes: catalase, urease, and glucose oxidase (GOx). The active motion is characterized by a mean-square displacement (MSD) analysis of optical video recordings and confirmed by dynamic light scattering (DLS) measurements. We found that the apparent diffusion coefficient was enhanced by up to 83%. In addition, using optical tweezers, we directly measured a holding force of 64 ± 16 fN, which was necessary to counteract the effective self-propulsion force generated by a single nanomotor. The successful demonstration of biocompatible enzyme-powered active nanomotors using biologically benign fuels has a great potential for future biomedical applications
Food science and technology 1946-1971-1996 : retrospect and prospect : past accomplishments and future challenges
THE EFFECT OF GAMMA RAYS ON MARINE FINFISH FILLETS INOCULATED WITH TYPE E, CLOSTRIDIUM BOTULINUM. Final Report, July 15, 1967--July 14, 1968.
THE EFFECT OF GAMMA RAYS ON OCEAN PERCH INOCULATED WITH TYPE E, CLOSTRIDIUM BOTULINUM. Annual Report, June 1966--June 1967.
Characteristics of Mesophilic Bacteria Isolated during Thermophilic Composting of Sewage Sludge
THE EFFECT OF REPEATED TREATMENT WITH GAMMA RAYS ON THE RADIO-RESISTANCE, VIRULENCE, AND CULTURE CHARACTERISTICS OF CERTAIN PATHOGENIC BACTERIA. Final Report.
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