Hear my voice: a community-based participatory study gathering the lived experiences of people with disabilities and older people in Tanzania

This is the final version of the article. Available from the publisher via the URL in this record.This study provides evidence on the specific nature and experiences of people with disabilities and older people from their own perspectives in rural and urban settings in Tanzania. Its aim was to better inform efforts to provide services for and improve the lives of people living in those regions. A community-based participatory approach was used, involving collaboration with the community. Peer researchers and research partners collected and analysed interviews with people with disabilities and older people, leading to policy and advocacy recommendations and early stage plans. Findings were framed in terms of experiences of participation and inclusion as impacted by physical, social and attitudinal factors, as well presented at individual, interpersonal and societal levels. They demonstrate how lack of access to healthcare and education, social limitations and powerful community attitudes were interwoven and exacerbated poverty in these contexts. Policy recommendations cover issues such as halting persecution and killings of people with albinism, support and guidance for families of children with disabilities, national policy on ageing legislation, and implementing and monitoring the UN Convention on the Rights of Persons with Disabilities

PENINGKATAN EKSISTENSI UMKM DI JABODETABEK MELALUI KOMUNITAS UKM (Usaha Kaum Milenial) DI ERA PANDEMI

Jumlah UMKM (Usaha Mikro Kecil Menengah) di Indonesia setiap tahun bertambah, termasuk UMKM pangan yang dikelola generasi milenial. Hal ini menyebabkan muncul tantangan dalam peningkatan kualitas produk dan pemasaran, terlebih pada era pendemi seperti ini. Pelatihan ini bertujuan untuk meningkatkan pengetahuan serta keterampilan mitra guna meningkatkan mutu produk termasuk kemasan dan pemasarannya. Kegiatan ini diikuti oleh 32 mitra dari Jabodetabek dan beberapa kota lain. Metode yang dilakukan adalah pendaftaran mitra, pembuatan grup komunitas, presentasi dan pelatihan online via Google Meet, dan evaluasi. Materi presentasi dibagi menjadi enam sesi yaitu opening class, sistem jaminan halal, sanitasi dan CPPOB (Cara Produksi Pangan Olahan yang Baik), strategi pemasaran, design kemasan, dan ijin edar produk pangan. Sebanyak 44% peserta memasarkan produknya secara online, 44% secara online dan offline, dan masih terdapat 12% memasarkan produk secara offline. Pada sesi pelatihan design kemasan dilakukan perubahan tampilan kemasan UMKM Nuris Chips menjadi lebih menarik dan kekinian. Hasil pretest dan postest didapatkan peningkatan pengetahuan dari nilai rata-rata pretest 67,22 menjadi 88,33 saat post test

Survai Aedes Aegypti L. (Diptera: Culicidae) Di Yogyakarta. Tempat Perkembangbiakan

Keyword :Aedes Aegypti L, Tempat Perkembangbiaka

Cell-mediated immune status in patients with squamous cell carcinoma of the oral cavity

Sixteen untreated patients with squamous cell carcinoma of the oral cavity were tested for in vitro immune status in comparison with the normal healthy donors. The parameters investigated were total leukocyte and lymphocyte counts, percentages and absolute counts of T- and B-cells in circulation, subsets of T-cells identified by the Fc receptors, phytohemagglutinin (PHA), and mixed lymphocyte culture (MLC) responses, natural killer (NK) and antibody-dependent cellular cytotoxicity (ADCC) activities, and circulating immune complexes (CICs). Eight of these patients were retested 3 to 6 months after surgery. The results showed that there was an increase in leukocyte and lymphocyte counts, an increase in the percentage and absolute number of B-lymphocytes, an increase in the percentage of T-gamma cells, suboptimal PHA and MLC responses, normal NK and ADCC activities, and increased levels of CICs in untreated oral cancer patients. In the postoperative stage, except for a reduction in leukocyte and lymphocyte counts, other abnormalities remained unchanged. The CICs in treated patients correlated with the tumor load in that in three patients showing recurrence, the CIC level remained elevated, whereas in patients without evidence of the disease the CIC level was either low or comparable to the upper normal limits

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer

Squamous cell carcinoma of the anorectal canal (SCCA) is a rare HPV-related malignancy that is steadily increasing in incidence. A high unmet need exists for patients with persistent loco-regional and metastatic disease. Axalimogene filolisbac (ADXS11-001) is an investigational immunotherapy that stimulates tumor-specific responses against HPV-associated cancers, and has demonstrated benefit in metastatic cervical cancer. We conducted this single-arm, multicenter, phase 2 trial in patients with persistent/recurrent, loco-regional or metastatic SCCA. Patients received ADXS11-001, 1 × 1

Modelling the impact of interventions on imported, introduced and indigenous malaria infections in Zanzibar, Tanzania

Malaria cases can be classified as imported, introduced or indigenous cases. The World Health Organization's definition of malaria elimination requires an area to demonstrate that no new indigenous cases have occurred in the last three years. Here, we present a stochastic metapopulation model of malaria transmission that distinguishes between imported, introduced and indigenous cases, and can be used to test the impact of new interventions in a setting with low transmission and ongoing case importation. We use human movement and malaria prevalence data from Zanzibar, Tanzania, to parameterise the model. We test increasing the coverage of interventions such as reactive case detection; implementing new interventions including reactive drug administration and treatment of infected travellers; and consider the potential impact of a reduction in transmission on Zanzibar and mainland Tanzania. We find that the majority of new cases on both major islands of Zanzibar are indigenous cases, despite high case importation rates. Combinations of interventions that increase the number of infections treated through reactive case detection or reactive drug administration can lead to substantial decreases in malaria incidence, but for elimination within the next 40 years, transmission reduction in both Zanzibar and mainland Tanzania is necessary