434 research outputs found

    Hankel determinant for a class of analytic functions of complex order defined by convolution

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    In this paper, we obtain the Fekete-Szego inequalities for the functions of complex order defined by convolution. Also, we find upper bounds for the second Hankel determinant a2a4a32|a_2a_4-a_3^2| for functions belonging to the class Sγb(g(z);A,B)S_{\gamma}^b(g(z);A,B)

    Inclusion and neighborhood properties of certain subclasses of p-valent functions of complex order defined by convolution

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    In this paper we introduce and investigate three new subclasses of pp-valent analytic functions by using the linear operator Dλ,pm(fg)(z)D_{\lambda,p}^m(f*g)(z). The various results obtained here for each of these function classes include coefficient bounds, distortion inequalities and associated inclusion relations for (n,θ)(n,\theta)-neighborhoods of subclasses of analytic and multivalent functions with negative coefficients, which are defined by means of a non-homogenous differential equation

    Tissue microarrays and their use for preparation of reference slides for educational purposes in histology and histopathology

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    Use of Tissue array was first applied in 1998, and has received a significant amount of attention from the research community ever since. In this technique, a large number (up to 1000) of cylindrical tissue core extracted from \"donor\" paraffin block are deposited into \"recipient\" block. The aim was modification of the technique of tissue array for manual preparation of the recipient block and production of slides of educational interest in histology and histopathology. The area of interest was localized with the help of stained section, the area was punctured, and the cylindrical core of tissue removed was then introduced into another (recipient) paraffin block. Puncture method was suitable only for parenchymatous organs (liver, kidney, heart, spleen, etc.) but longitudinal sections were required for tubular (gastrointestinal tract, urinary tract, genital tract) and hollow organs (gallbladder, urinary bladder) and brain. The method described is of importance in procurement of materials for preparation of slides for educational purposes and in overcoming the shortage of these materials especially in the field of pathology African Journal of Health Sciences Vol. 13 (3-4) 2006: pp. 66-6

    Correlation Between Vicia ervilia L. Willd. Antibacterial Activity and Its Phenolic Content

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    Context: Plants are important in devising new antibacterial drugs. Unlike several fabaceae seeds, Vicia ervilia L. Willd., is not used up till now for human consumption. Objective: evaluate antibacterial potential of the seeds and correlate it, if any, with its phenolics. Methods: Seeds ethanol (SEE), aqueous (SAE), and methanol (SME) extracts were prepared. Their total phenolic content (TPC) was determined spectrophotometrically. Antibacterial activity against ten pathogenic bacteria (Mycobacterium africanum, M. bovis, M. caprae, M. microti, M. orygis, Staphylococcus aureus, Streptococcus  pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Salmonella typhimurium) was evaluated using agar well diffusion assay. Also the minimum inhibitory and bactericidal concentrations (MIC & MBC) were also determined.  Results: Total phenolic content of SME is significantly (p<0.001) higher than that of SEE (4.8 and 2.5µg/mg gallic acid equivalent respectively). SME and SEE significantly inhibit the growth of all tested strains except M. caprae and P. aeruginosa. V. ervilia L. Conclusion: The seeds significant antibacterial activity was attributed to its phenolics. Keywords: phenolics, antibacterial activit

    Isolation of biologically active metabolites from Bougainvillea spectabilis Willd. cultivated in Egypt

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    Bougainvillea spectabilis Willd.  is an ornamental plant cultivated in tropical, subtropical regions and other places as Egypt. The present study aimed to perform bioassay guided fractionation and isolation of some of the bioactive compounds from the Egyptian cultivate. The total ethanol extracts of the leaves (T.ET.L.), stems (T.ET.S.) and flowers (T.ET.F.) were screened for some pharmacological activities viz. in vivo anti-oxidant and anti-hepatotoxic, in addition to in vitro cytotoxic activities. The anti-oxidant effect was assessed by measuring serum glutathione level (GSH) in alloxan-induced diabetic rats. The anti-hepatotoxic activity was evaluated via measuring serum markers level viz. alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) in CCl4-induced hepatotoxicity in rats. In vitro cytotoxicity of the different extracts was estimated for liver cancer cell line (HEPG2) adopting Sulforhodamine B stain assay. T.ET.L. exhibited significantly potent anti-oxidant and anti-hepatotoxic activities, while T.ET.S. showed the highest cytotoxic activity. Through biological guided fractionation, leaves and stems were subjected to successive solvent extraction, whereas the leaves ethyl acetate (Et.Ac.L.) and the stems ethanol 70% (Et.70%S.) extracts showed highly potent activities. Thus, different chromatographic techniques were performed on Et.Ac.L. and Et.70%S. extracts leading to the isolation of five bioactive metabolites. Three flavonoids were isolated from Et.Ac.L.; genistein-7-O-rutinoside (1), formononetin-7-O-rutinoside (2) and myricetin (3), while orobol-7-O-glucoside (4) and hesperidin (5) were isolated from Et.70%S. This work demonstrated the importance of the plant as a promising anti-oxidant, anti-hepatotoxic and cytotoxic product for nutraceutical use

    Differential sandwich theorems for p-valent functions associated with generalized multiplier transformations

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    In this paper, we obtain some applications of theory of differential subordination, superordination and sandwich results involving an operator

    Bridging Medical Simulation with Computer Science and Engineering: A Growing Field of Study

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    Objectives: The aim of this study was to determine if having on-site technological expertise will allow for the facile navigation of high fidelity manikins within nursing programs as well as to assess if the level of understanding and interest among engineering students would increase as a result of attending a class related to the technology used in healthcare simulation. Methods: Two assessments were applied to engineering students attending a class of technology used in healthcare simulation. A pre-test was designed to measure the understanding and interest of students in the engineering/computer science courses before attending a simulation class. A post-test assessment was used to measure their improvement in understanding and interest to learn more about simulation technologies. Participants: Engineering students attending 6 different engineering programs (Computer Science, Computer Engineering, Mechanical Engineering, Biomedical Engineering, Electrical Engineering and Technology Management) and having different educational levels (undergraduate and graduate)

    Hepatitis C Infection Patterns at a Tertiary Care Center in New York: A Cross-Sectional Study.

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    Introduction In the United States, 2.7 to 3.9 million patients are infected with the hepatitis C virus (HCV) with 3,500 new cases reported yearly. According to the Centers for Disease Control and Prevention, HCV was the underlying or contributing cause of death of 19,659 patients in 2014. These facts underscore the need for a better understanding of the scope of this disease. Our epidemiologic study aimed at analyzing the pattern of occurrence of HCV infection at Staten Island University Hospital (SIUH) by evaluating the characteristics of newly infected patients with hepatitis C in 2014. The identified features served to better distinguish the targets for preventive health care in our particular population. Methodology A cross-sectional study of all newly diagnosed patients with HCV infections in the year 2014 presenting to SIUH was conducted using International Classification of Disease-9 codes (ICD-9) for hepatitis C. We included all patients with a positive HCV antibody confirmed by polymerase chain reaction testing. Patients were divided into groups according to age to simulate the age groups in the 2013 - 2014 Hepatitis B and C Annual Report of the New York City (NYC) Department of Health and Mental Hygiene published in 2016 (abbreviated to 2014 NYCDOH Report, hereafter). Gender and HCV genotypes were also collected. We compared disease frequency between age groups, gender, and genotype with the results of the 2014 NYCDOH Report. Results A total of 378 newly diagnosed HCV cases were identified; 60.05% were men, and 39.95% were women. The rate of infection with genotype 1a was the highest (36. 5%) followed by 1b (25.9%). In women, genotype 1b was predominant (13.76%) versus genotype 1a as the most common in men. The mean age was 54 years for men and 57 years for women. Most cases fell into the 60 to 69-year age group (32.28%), followed by the 50 to 59-year age group (31.48%). More so, all patients 80 years and older were exclusively women. Conclusions We found most new HCV infections at SIUH were diagnosed in patients aged 60 to 69 years, and the 2014 NYC DOH Report indicates most new HCV infections occur in patients aged 40 to 59 years. Also, all HCV infections detected in patients older than 80 years of age were found in women. These findings provide a better understanding of the patient demographics for appropriate HCV screening policies. Increased awareness and strict adherence to screening policies in baby boomers and high-risk populations are paramount in order to diagnose HCV infection early, offer therapy, and prevent HCV-related mortality and morbidity

    The correlation between Aflatoxin B1 and Placental Apoptosis in Pregnant women with Intrauterine Growth Restriction

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    Objective:To explore the effect of Aflatoxin B1 toxicity as a risk factor of intrauterine growth restriction (IUGR) and to determine the role of placental apoptotic indices in the pathogenesis of IUGR and their association with maternal risk factors including residency, working and exposure to smoking. Materials and Methods:A case-control study was done at Women Health Hospital; Assiut University, Egypt. Sixty pregnant women with asymmetrical IUGR and a control group of 40 normal pregnancies were selected. Maternal urine samples were obtained for Aflatoxin B1 level measurement by layer chromatography. Quantitative determination of human placental Bcl-2 and caspase-3 using a monoclonal antibody-based enzyme-linked immunosorbent assay kits were performed. Results:The results showed that aflatoxin B1 positive cases in the IUGR group had significantly higher placental caspase-3 and lower placental Bcl-2 concentrations than those which were aflatoxin B1 negative (p<0.01). The levels of placental apoptotic indices were higher in working women who lived in urban areas and those exposed to cigarette smoke than non-working women who lived in rural areas and non-smokers. Conclusions: Aflatoxin B1 may affect the fetal growth by increasing the placental apoptosis. These results may highlight the importance of aflatoxin B1 which may contribute to the complex etiology of IUGR. Placental apoptotic indices levels were significantly affected by maternal residence, working and exposure to smoking in pregnancies complicated with IUGR

    5-Isopropyl­imidazolidine-2,4-dione monohydrate

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    In the title compound, C6H10N2O2·H2O, the imidazole ring is essentially planar, with a maximum deviation of 0.012 (2) Å. In the crystal, mol­ecules are connected via N—H⋯O and O—H⋯O hydrogen bonds, forming a supra­molecular tape along the a axis
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