75 research outputs found
Possible links between groundwater geochemistry and chronic kidney disease of unknown etiology (CKDu): an investigation from the Ginnoruwa Region in Sri Lanka
Since at least two decades, Chronic Kidney Disease of Uncertain Etiology (CKDu) has become an increasingly discussed health issue in Sri Lanka and as well as in other tropical regions. Areas that are particularly afected with the disease are mostly located in the dry zone of Sri Lanka. The disease is more prominent among communities that consume groundwater as their main source of drinking water. Hydrogeochemical investigations were carried out in the Ginnoruwa area, a known hotspot of CKDu. It revealed possible links between drinking water chemistry and the spreading of the disease. This work compares hydrogeochemical data of drinking water sources of wells whose consumers are afected by CKDu and other nearby wells whose consumers were not afected by the disease. A total of 63 groundwater samples were collected from selected wells. About one-third of these samples (i.e., 19) were collected from wells used by CKDu patients. Signifcantly higher values of pH, total hardness, electrical conductivity, Ca2+, Mg2+, F-, Cl-, PO4 3-, and SO4 2- were found in wells that were used by CKDu patients. Mean contents of Na+, Ca2+, and Mg2+ in CKDu afected wells were 33.8 mg/L, 30.1 mg/L, and 14.9 mg/L, respectively, compared to 23.1 mg/L, 26.7 mg/L, and 9.65 mg/L in non-CKDu wells. Diferences in major ion geochemistry in groundwaters are possibly governed by variable time periods of water storage in fractured hard rock aquifers in this region. Hydrogeochemical parameters were statistically compared by a Mann–Whitney U test and indicated signifcant diferences in total dissolved solids (TDS) (p=0.016), SO4 2- (p=0.005), PO4 3- (p=0.030), F- (p=0.048), Na+ (p=0.008), and Mg2+(p=0.008) between non-CKDu and CKDu wells at p=0.050 level. Other suspected solutes such as nephrotoxic trace elements including As, Cd, and Pb were similar in both types of wells. They were also lower than the accepted guideline limits of the World Health Organization (WHO). Results of this study suggest that fuoride in drinking water in combination with water hardness may be one of the responsible factors for kidney damage and progression of the disease. This may be particularly the case when elevated amounts of Mg2+ are present in hard groundwater
High-pressure study of lithium amidoborane using Raman spectroscopy and insight into dihydrogen bonding absence
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Metal Effect on the Supramolecular Structure, Photophysics, and Acid-Base Character of Trinuclear Pyrazolato Coinage Metal Complexes
This article discusses the metal effect on the supramolecular structure, photophysics, and acid-base character of trinuclear pyrazolato coinage metal complexes
Antimony contamination and its risk management in complex environmental settings:A review
Antimony (Sb) is introduced into soils, sediments, and aquatic environments from various sources such as weathering of sulfide ores, leaching of mining wastes, and anthropogenic activities. High Sb concentrations are toxic to ecosystems and potentially to public health via the accumulation in food chain. Although Sb is poisonous and carcinogenic to humans, the exact mechanisms causing toxicity still remain unclear. Most studies concerning the remediation of soils and aquatic environments contaminated with Sb have evaluated various amendments that reduce Sb bioavailability and toxicity. However, there is no comprehensive review on the biogeochemistry and transformation of Sb related to its remediation. Therefore, the present review summarizes: (1) the sources of Sb and its geochemical distribution and speciation in soils and aquatic environments, (2) the biogeochemical processes that govern Sb mobilization, bioavailability, toxicity in soils and aquatic environments, and possible threats to human and ecosystem health, and (3) the approaches used to remediate Sb-contaminated soils and water and mitigate potential environmental and health risks. Knowledge gaps and future research needs also are discussed. The review presents up-to-date knowledge about the fate of Sb in soils and aquatic environments and contributes to an important insight into the environmental hazards of Sb. The findings from the review should help to develop innovative and appropriate technologies for controlling Sb bioavailability and toxicity and sustainably managing Sb-polluted soils and water, subsequently minimizing its environmental and human health risks
Metal Effect on the Supramolecular Structure, Photophysics, and Acid-Base Character of Trinuclear Pyrazolato Coinage Metal Complexes
Theoretical study of elementary reactions of dehydrogenation of magnesium, calcium, zinc, and beryllium amminoborate and amminoalanate complexes
Ammonia Borane Confined by a Metal−Organic Framework for Chemical Hydrogen Storage: Enhancing Kinetics and Eliminating Ammonia
Arsenic and cadmium concentrations in legumes and cereals grown in the North Central Province, Sri Lanka and assessment of their health risk
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