Geometrical considerations in the separation of biological particles by affinity partitioning

A theoretical description of the affinity partitioning effect is presented. Experiments at reduced and zero g are discussed

A power filter for the detection of burst sources of gravitational radiation in interferometric detectors

We present a filter for detecting gravitational wave signals from burst sources. This filter requires only minimal advance knowledge of the expected signal: i.e. the signal's frequency band and time duration. It consists of a threshold on the total power in the data stream in the specified signal band during the specified time. This filter is optimal (in the Neyman-Pearson sense) for signal searches where only this minimal information is available.Comment: 3 pages, RevTeX, GWDAW '99 proceedings contribution, submitted to Int. J. Modern Phys.

Hydrogen absorption properties of amorphous (Ni0.6Nb0.4−yTay)100−xZrx membranes

Ni based amorphous materials have great potential as hydrogen purification membranes. In the present work the melt spun (Ni0.6Nb0.4−yTay)100−xZrx with y=0, 0.1 and x=20, 30 was studied. The result of X-ray diffraction spectra of the ribbons showed an amorphous nature of the alloys. Heating these ribbons below T < 400 °C, even in a hydrogen atmosphere (1−10 bar), the amorphous structure was retained. The crystallization process was characterized by differential thermal analysis and the activation energy of such process was obtained. The hydrogen absorption properties of the samples in their amorphous state were studied by the volumetric method, and the results showed that the addition of Ta did not significantly influence the absorption properties, a clear change of the hydrogen solubility was observed with the variation of the Zr content. The values of the hydrogenation enthalpy changed from ~37 kJ/mol for x=30 to ~9 kJ/mol for x=20. The analysis of the volumetric data provides the indications about the hydrogen occupation sites during hydrogenation, suggesting that at the beginning of the absorption process the deepest energy levels are occupied, while only shallower energy levels are available at higher hydrogen content, with the available interstitial sites forming a continuum of energy levels

Data analysis strategies for the detection of gravitational waves in non-Gaussian noise

In order to analyze data produced by the kilometer-scale gravitational wave detectors that will begin operation early next century, one needs to develop robust statistical tools capable of extracting weak signals from the detector noise. This noise will likely have non-stationary and non-Gaussian components. To facilitate the construction of robust detection techniques, I present a simple two-component noise model that consists of a background of Gaussian noise as well as stochastic noise bursts. The optimal detection statistic obtained for such a noise model incorporates a natural veto which suppresses spurious events that would be caused by the noise bursts. When two detectors are present, I show that the optimal statistic for the non-Gaussian noise model can be approximated by a simple coincidence detection strategy. For simulated detector noise containing noise bursts, I compare the operating characteristics of (i) a locally optimal detection statistic (which has nearly-optimal behavior for small signal amplitudes) for the non-Gaussian noise model, (ii) a standard coincidence-style detection strategy, and (iii) the optimal statistic for Gaussian noise.Comment: 5 pages RevTeX, 4 figure

Ionization Structure and the Reverse Shock in E0102-72

The young oxygen-rich supernova remnant E0102-72 in the Small Magellanic Cloud has been observed with the High Energy Transmission Grating Spectrometer of Chandra. The high resolution X-ray spectrum reveals images of the remnant in the light of individual emission lines of oxygen, neon, magnesium and silicon. The peak emission region for hydrogen-like ions lies at larger radial distance from the SNR center than the corresponding helium-like ions, suggesting passage of the ejecta through the "reverse shock". We examine models which test this interpretation, and we discuss the implications.Comment: 4 pages, 6 figures; To appear in "Young Supernova Remnants" (11th Annual Astrophysics Conference in Maryland), S. S. Holt & U. Hwang (eds), AIP, New York (2001

Quantum field theory and time machines

We analyze the "F-locality condition" (proposed by Kay to be a mathematical implementation of a philosophical bias related to the equivalence principle, we call it the "GH-equivalence principle"), which is often used to build a generalization of quantum field theory to non-globally hyperbolic spacetimes. In particular we argue that the theorem proved by Kay, Radzikowski, and Wald to the effect that time machines with compactly generated Cauchy horizons are incompatible with the F-locality condition actually does not support the "chronology protection conjecture", but rather testifies that the F-locality condition must be modified or abandoned. We also show that this condition imposes a severe restriction on the geometry of the world (it is just this restriction that comes into conflict with the existence of a time machine), which does not follow from the above mentioned philosophical bias. So, one need not sacrifice the GH-equivalence principle to "emend" the F-locality condition. As an example we consider a particular modification, the "MF-locality condition". The theory obtained by replacing the F-locality condition with the MF-locality condition possesses a few attractive features. One of them is that it is consistent with both locality and the existence of time machines.Comment: Revtex, 14 pages, 1 .ps figure. To appear in Phys. Rev. D More detailed discussion is given on the MF-locality condition. Minor corrections in terminolog

Nifedipine in Congenital Hyperinsulinism - A Case Report.

PublishedJournal ArticleThis is the final version of the article. Available from Galenos Yayınevi via the DOI in this record.Congenital hyperinsulinism (CHI) is the commonest cause of persistent hypoglycemia in neonates. Diazoxide is the first-line drug in its treatment, but the more severe cases are usually diazoxide-resistant. Recessive ABCC8 and KCNJ11 mutations are responsible for most (82%) of the severe diazoxide-unresponsive CHI. Oral nifedipine has been effective in isolated cases of CHI. Successful treatment of diazoxide-unresponsive CHI with a combination of octreotide and nifedipine has been reported in a single isolated case so far. We report here a case of diazoxide-resistant CHI due to homozygous ABCC8 nonsense mutation. In this case, hypoglycaemia uncontrolled by pancreatectomy and octreotide alone showed a good response to a combination of nifedipine and octreotide. Octreotide was tapered off by one year age and thereafter the child is euglycaemic on oral nifedipine alone. Continuous glucose monitoring sensor was used as an aid to monitor glycaemic control and was found to be a safe and reliable option reducing the number of needle-pricks in small children

Best chirplet chain: near-optimal detection of gravitational wave chirps

The list of putative sources of gravitational waves possibly detected by the ongoing worldwide network of large scale interferometers has been continuously growing in the last years. For some of them, the detection is made difficult by the lack of a complete information about the expected signal. We concentrate on the case where the expected GW is a quasi-periodic frequency modulated signal i.e., a chirp. In this article, we address the question of detecting an a priori unknown GW chirp. We introduce a general chirp model and claim that it includes all physically realistic GW chirps. We produce a finite grid of template waveforms which samples the resulting set of possible chirps. If we follow the classical approach (used for the detection of inspiralling binary chirps, for instance), we would build a bank of quadrature matched filters comparing the data to each of the templates of this grid. The detection would then be achieved by thresholding the output, the maximum giving the individual which best fits the data. In the present case, this exhaustive search is not tractable because of the very large number of templates in the grid. We show that the exhaustive search can be reformulated (using approximations) as a pattern search in the time-frequency plane. This motivates an approximate but feasible alternative solution which is clearly linked to the optimal one. [abridged version of the abstract]Comment: 23 pages, 9 figures. Accepted for publication in Phys. Rev D Some typos corrected and changes made according to referee's comment

Spectral Line Imaging Observations of 1E0102.2-7219

E0102-72 is the second brightest X-ray source in the Small Magellanic Cloud and the brightest supernova remnant in the SMC. We observed this SNR for ~140 ksec with the High Energy Transmission Gratings (HETG) aboard the Chandra X-ray Observatory. The small angular size and high surface brightness make this an excellent target for HETG and we resolve the remnant into individual lines. We observe fluxes from several lines which include O VIII Ly$\alpha$, Ly$\beta$, and O VII along with several lines from Ne X, Ne IX and Mg XII. These line ratios provide powerful constraints on the electron temperature and the ionization age of the remnant.Comment: To appear in "Young Supernova Remnants" (11th Annual Astrophysics Conference in Maryland), S. S. Holt & U. Hwang (eds), AIP, New York (2001