1,071 research outputs found
The church in a postliberal age
Title: The church in a postliberal age. Author: Lindbeck, George A Church in a postliberal age 300 p. Publisher: [S.l.] : Eerdmans, 2002
On large deviation regimes for random media models
The focus of this article is on the different behavior of large deviations of
random subadditive functionals above the mean versus large deviations below the
mean in two random media models. We consider the point-to-point first passage
percolation time on and a last passage percolation time
. For these functionals, we have and
. Typically, the large deviations for such
functionals exhibits a strong asymmetry, large deviations above the limiting
value are radically different from large deviations below this quantity. We
develop robust techniques to quantify and explain the differences.Comment: Published in at http://dx.doi.org/10.1214/08-AAP535 the Annals of
Applied Probability (http://www.imstat.org/aap/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Continuous Model for Homopolymers
We consider the model for the distribution of a long homopolymer in a
potential field. The typical shape of the polymer depends on the temperature
parameter. We show that at a critical value of the temperature the transition
occurs from a globular to an extended phase. For various values of the
temperature, including those at or near the critical value, we consider the
limiting behavior of the polymer when its size tends to infinity
On large deviations for the parabolic Anderson model
The focus of this article is on the different behavior of large deviations of random functionals associated with the parabolic Anderson model above the mean versus large deviations below the mean. The functionals we treat are the solution u(x, t) to the spatially discrete parabolic Anderson model and a functional A
n
which is used in analyzing the a.s. Lyapunov exponent for u(x, t). Both satisfy a “law of large numbers”, with
and
. We then think of αn and λ(κ)t as being the mean of the respective quantities A
n
and log u(t, x). Typically, the large deviations for such functionals exhibits a strong asymmetry; large deviations above the mean take on a different order of magnitude from large deviations below the mean. We develop robust techniques to quantify and explain the differences
Improved underwater image enhancement algorithms based on partial differential equations (PDEs)
The experimental results of improved underwater image enhancement algorithms
based on partial differential equations (PDEs) are presented in this report.
This second work extends the study of previous work and incorporating several
improvements into the revised algorithm. Experiments show the evidence of the
improvements when compared to previously proposed approaches and other
conventional algorithms found in the literature.Comment: 22 pages, 6 figure
Uniform shrinking and expansion under isotropic Brownian flows
We study some finite time transport properties of isotropic Brownian flows.
Under a certain nondegeneracy condition on the potential spectral measure, we
prove that uniform shrinking or expansion of balls under the flow over some
bounded time interval can happen with positive probability. We also provide a
control theorem for isotropic Brownian flows with drift. Finally, we apply the
above results to show that under the nondegeneracy condition the length of a
rectifiable curve evolving in an isotropic Brownian flow with strictly negative
top Lyapunov exponent converges to zero as with positive
probability
Human bladder cancer invasion model using rat bladder in vitro and its use to test mechanisms and therapeutic inhibitors of invasion
As well as being a passive support, the extracellular matrix also regulates key biological processes such as invasion, differentiation and angiogenesis. We have therefore developed an in vitro model of bladder cancer invasion using de-epithelialized rat bladder to allow for tumour cell–extracellular matrix interactions. Onto this we have seeded a panel of human bladder cancer cell lines (RT4, RT112, 253J and EJ28 (T24)) representing progression from well to poorly differentiated phenotypes and used as models of superficial to invasive bladder cancer. The better differentiated cell lines RT4 and RT112 reproducibly grew as stratified epithelium, whereas poorly differentiated EJ28 cells invaded across a broad front. Invasion was not simply related to proliferation rate, measured either as doubling time on plastic (non-invasive 253J and invasive EJ28 having the same doubling time) or by Ki-67 proliferation index within the model. We used the model to test the ability of 4 compounds that interfere with tumour cell–extracellular matrix interactions (suramin, N-acetylcysteine and the urokinase plasminogen activator pathway antagonists Å5 compound and monoclonal antibody Mab 3936) to inhibit invasion. At non-toxic concentrations, all significantly inhibited invasion (P< 0.05), although to varying degrees, suramin and Å5 almost completely and N-acetylcysteine the least. In conclusion, this model shows the urokinase system is important for bladder invasion and can be used to investigate other mechanisms of bladder cancer invasion and also for the testing of intravesical drugs. © 2001 Cancer Research Campaign http://www.bjcancer.co
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