Anti-microbial Use in Animals: How to Assess the Trade-offs

Antimicrobials are widely used in preventive and curative medicine in animals. Benefits from curative use are clear – it allows sick animals to be healthy with a gain in human welfare. The case for preventive use of antimicrobials is less clear cut with debates on the value of antimicrobials as growth promoters in the intensive livestock industries. The possible benefits from the use of antimicrobials need to be balanced against their cost and the increased risk of emergence of resistance due to their use in animals. The study examines the importance of animals in society and how the role and management of animals is changing including the use of antimicrobials. It proposes an economic framework to assess the trade-offs of anti-microbial use and examines the current level of data collection and analysis of these trade-offs. An exploratory review identifies a number of weaknesses. Rarely are we consistent in the frameworks applied to the economic assessment anti-microbial use in animals, which may well be due to gaps in data or the prejudices of the analysts. There is a need for more careful data collection that would allow information on (i) which species and production systems antimicrobials are used in, (ii) what active substance of antimicrobials and the application method and (iii) what dosage rates. The species need to include companion animals as well as the farmed animals as it is still not known how important direct versus indirect spread of resistance to humans is. In addition, research is needed on pricing antimicrobials used in animals to ensure that prices reflect production and marketing costs, the fixed costs of anti-microbial development and the externalities of resistance emergence. Overall, much work is needed to provide greater guidance to policy, and such work should be informed by rigorous data collection and analysis systems

Boosting OMD for Almost Free Authentication of Associated Data

We propose pure OMD (p-OMD) as a new variant of the Offset Merkle-Damgård (OMD) authenticated encryption scheme. Our new scheme inherits all desirable security features of OMD while having a more compact structure and providing higher efficiency. The original OMD scheme, as submitted to the CAESAR competition, couples a single pass of a variant of the Merkle-Damgård (MD) iteration with the counter-based XOR MAC algorithm to provide privacy and authenticity. Our improved p-OMD scheme dispenses with the XOR MAC algorithm and is purely based on the MD iteration; hence, the name ``pure'' OMD. To process a message of $\ell$ blocks and associated data of $a$ blocks, OMD needs $\ell+a+2$ calls to the compression function while p-OMD only requires max{$\ell, a$}+$2$ calls. Therefore, for a typical case where $\ell \geq a$, p-OMD makes just $\ell+2$ calls to the compression function; that is, associated data is processed almost freely compared to OMD. We prove the security of p-OMD under the same standard assumption (pseudo-randomness of the compression function) as made in OMD; moreover, the security bound for p-OMD is the same as that of OMD, showing that the modifications made to boost the performance are without any loss of security

Breaking Symmetric Cryptosystems Using Quantum Period Finding

Due to Shor's algorithm, quantum computers are a severe threat for public key cryptography. This motivated the cryptographic community to search for quantum-safe solutions. On the other hand, the impact of quantum computing on secret key cryptography is much less understood. In this paper, we consider attacks where an adversary can query an oracle implementing a cryptographic primitive in a quantum superposition of different states. This model gives a lot of power to the adversary, but recent results show that it is nonetheless possible to build secure cryptosystems in it. We study applications of a quantum procedure called Simon's algorithm (the simplest quantum period finding algorithm) in order to attack symmetric cryptosystems in this model. Following previous works in this direction, we show that several classical attacks based on finding collisions can be dramatically sped up using Simon's algorithm: finding a collision requires $\Omega(2^{n/2})$ queries in the classical setting, but when collisions happen with some hidden periodicity, they can be found with only $O(n)$ queries in the quantum model. We obtain attacks with very strong implications. First, we show that the most widely used modes of operation for authentication and authenticated encryption e.g. CBC-MAC, PMAC, GMAC, GCM, and OCB) are completely broken in this security model. Our attacks are also applicable to many CAESAR candidates: CLOC, AEZ, COPA, OTR, POET, OMD, and Minalpher. This is quite surprising compared to the situation with encryption modes: Anand et al. show that standard modes are secure with a quantum-secure PRF. Second, we show that Simon's algorithm can also be applied to slide attacks, leading to an exponential speed-up of a classical symmetric cryptanalysis technique in the quantum model.Comment: 31 pages, 14 figure

Thermal, pressure and wind fields at ground level in the area of the Italian base at Terra Nova Bay, Victoria Land, Antarctica, as observed by a network of automatic weather stations

Ground temperature, pressure and wind speed monthly averages in the area of the Italian Station at Terra Nova Bay, Antarctica, were analyzed for the period 1987–1991 by means of a network of nine AWS (automatic weather stations). Spatial configurations of temperature show a well-defined, relatively warm island in the area of Terra Nova Bay, between Drygalsky and Campbell ice tongues, throughout the year. A second warm island is present to the north along the coast, between Aviator and Mariner ice tongues, for most of the year. From February to March a rapid drop in temperature is observed at all stations. A strong thermal gradient develops during February, March, April and October, November, December, between the coastal region and inner highlands. The baric configuration follows the elevation of the area. Annual average pressure and temperature as functions of stations altitude show linear trends. Severe katabatic wind episodes are recorded at all stations, with wind speed exceeding 25 m s–1 and direction following the orographic features of the inner areas. Co-occurrences of these episodes were observed for stations located along stream lines of cold air drainage. The autocorrelation function of maximum wind speed time series shows wind persistence of 2–3 days and wind periodicity of about one week

Mediazione e negoziazione assistita nelle controversie con la p.a.: modelli a confronto (pubblicato 12.1.2021)

Il contributo affronta il tema della possibile estensione della mediazione al campo del diritto e del processo amministrativo, analizzando alcuni profili problematici della tematica sul piano teorico ed applicativo. Si propone quale alternativa a tale strumento di ADR, non esente da rilevanti criticità sul piano anche pratico, l’impiego del più duttile istituto della negoziazione assistita, la cui disciplina positiva (risalente al 2014) potrebbe essere agevolmente adattata alle controversie tra privato e pubblica amministrazione. Si esaminano i tratti salienti della normativa vigente e si avanzano alcuni suggerimenti de iure condendo per l’introduzione della negoziazione assistita amministrativa (NAA) quale precipuo ed innovativo strumento di deflazione delle liti innanzi ai Tribunali Amministrativi Regional

La radiazione solare globale al suolo in Italia nel 1995. Valori medi mensili stimati dalle immagini fornite dal satellite Meteosat

Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal