Jupiter's polar ionospheric flows: measured intensity and velocity variations poleward of the main auroral oval

Recent analysis of high-resolution spectra of Doppler-shifted H3+ emission from the auroral/polar regions of Jupiter revealed a complex wind system, with a persistent auroral electrojet and strong anti-sunward flows in a region of lesser intensity centred around the magnetic pole [ Stallard et al., 2001 ]. This region, which we have called the Dark Polar Region (DPR), is re-investigated, transforming the observed line-of-sight velocities into a frame of reference fixed with respect to the magnetic pole. The DPR is shown to include a region essentially stagnant in this frame of reference (the f-DPR). We identify it as a region coupled to open magnetotail field lines. There is also a transition region in which the ion velocity returns to corotation (the r-DPR)

APOE genotype and entorhinal cortex volume in non-demented community-dwelling adults in midlife and early old age

Copyright © 2012 IOS PressThis article has been made available through the Brunel Open Access Publishing Fund.The apolipoprotein E (APOE) ε4 allele is a risk factor for the neuropathological decline accompanying Alzheimer's disease (AD) while, conversely, the ε2 allele offers protection. One of the brain structures exhibiting the earliest changes associated with the disease is the entorhinal cortex. We therefore investigated the volumes of the entorhinal cortex and other structures in the medial temporal lobe including the parahippocampal gyrus, temporal pole, and inferior, middle, and superior temporal cortices, in relation to APOE genotype. Our main objectives were to determine if (a) volumes systematically varied according to allele in a stepwise fashion, ε2 > ε3 > ε4, and (b) associations varied according to age. We investigate this association in 627 non-demented community-dwelling adults in middle age (44 to 48 years; n = 314) and older age (64 to 68 years; n = 313) who underwent structural MRI scans. We found no evidence of APOE-related variation in brain volumes in the age groups examined. We conclude that if a ε2 > ε3 > ε4 pattern in brain volumes does emerge in non-demented adults living in the community in old age, it is not until after the age of 68 years.This study was funded by the UK Leverhulme Trust, the British Academy, the NHMRC Research Fellowship No. 471501, the NHMRC Research Fellowship No.#1002560, the National Health and Medical Research Council of Australia Unit Grant No. 973302, Program Grant No. 179805, Project grant No. 157125; Program grant no. 350833, and the National Computational Infrastructure. This article is made available through the Brunel Open Access Publishing Fund

Cognitive Deficits Are Associated with Frontal and Temporal Lobe White Matter Lesions in Middle-Aged Adults Living in the Community

BACKGROUND The association between brain white matter lesions and cognitive impairment in old age is well established. However, little is known about this association in midlife. As this information will inform policy for early preventative healthcare initiatives, we investigated non-periventricular frontal, temporal, parietal and occipital lobe white matter hyperintensities (WMH) in relation to cognitive function in 428 (232 women) community-dwelling adults aged 44 to 48 years. RESULTS Frontal white matter lesions were significantly associated with greater intraindividual RT variability in women, while temporal WMH were associated with face recognition deficits in men. Parietal and occipital lobe lesions were unrelated to cognitive performance. These findings did not differ when education and a range of health variables, including vascular risk factors, were taken into account. CONCLUSION Gender differences in WMH-cognition associations are discussed, and we conclude that small vessel disease is present in midlife and has functional consequences which are generally not recognized. Preventative strategies should, therefore, begin early in life.David Bunce's collaboration in this work was supported by the Leverhulme Trust and the British Academy. The study was funded by NHMRC of Australia Unit Grant No. 973302, Program Grant No. 179805, NHMRC project grant No. 157125, grants from the Australian Rotary Health Research Fund and the Australian Brewers Foundation. Nicolas Cherbuin is funded by NHMRC Research Fellowship No. 471501. Kaarin Anstey is funded by NHMRC Research Fellowship No. 366756. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript

A Systematic Review of Longitudinal Associations Between Reaction Time Intraindividual Variability and Age-Related Cognitive Decline or Impairment, Dementia, and Mortality.

OBJECTIVES: Intraindividual variability (IIV) in reaction time refers to the trial-to-trial fluctuations in responding across a given cognitive task. Cross-sectional research suggests that IIV increases with normal and neuropathological ageing and it may serve as a marker of neurobiological integrity. This raises the possibility that IIV may also predict future cognitive decline and, indeed, neuropathology. Therefore, we conducted a systematic review to address these issues. METHODS: A search of electronic databases Embase, Medline, PsycINFO, and Web of Science was completed on May 17, 2016 that identified longitudinal investigations of IIV in middle-aged or older adults. RESULTS: A total of 688 studies were initially identified of which 22 met the inclusion criteria. Nine included longitudinal IIV measures and 17 predicted subsequent outcome (cognitive decline or impairment, dementia, mortality) from baseline IIV. The results suggested IIV increased over time, particularly in participants aged over 75 years. Greater baseline IIV was consistently associated with increased risk of adverse outcomes including cognitive decline or impairment, and mortality. CONCLUSIONS: Increased IIV over time is associated with normal ageing. However, further increases in IIV over and above those found in normal ageing may be a risk factor for future cognitive impairment or mortality. Measures of IIV may, therefore, have considerable potential as a supplement to existing clinical assessment to aid identification of individuals at risk of adverse outcomes such as dementia or death

A Systematic Review of Longitudinal Associations Between Reaction Time Intraindividual Variability and Age-Related Cognitive Decline or Impairment, Dementia, and Mortality.

OBJECTIVES: Intraindividual variability (IIV) in reaction time refers to the trial-to-trial fluctuations in responding across a given cognitive task. Cross-sectional research suggests that IIV increases with normal and neuropathological ageing and it may serve as a marker of neurobiological integrity. This raises the possibility that IIV may also predict future cognitive decline and, indeed, neuropathology. Therefore, we conducted a systematic review to address these issues. METHODS: A search of electronic databases Embase, Medline, PsycINFO, and Web of Science was completed on May 17, 2016 that identified longitudinal investigations of IIV in middle-aged or older adults. RESULTS: A total of 688 studies were initially identified of which 22 met the inclusion criteria. Nine included longitudinal IIV measures and 17 predicted subsequent outcome (cognitive decline or impairment, dementia, mortality) from baseline IIV. The results suggested IIV increased over time, particularly in participants aged over 75 years. Greater baseline IIV was consistently associated with increased risk of adverse outcomes including cognitive decline or impairment, and mortality. CONCLUSIONS: Increased IIV over time is associated with normal ageing. However, further increases in IIV over and above those found in normal ageing may be a risk factor for future cognitive impairment or mortality. Measures of IIV may, therefore, have considerable potential as a supplement to existing clinical assessment to aid identification of individuals at risk of adverse outcomes such as dementia or death

INTRODUCTION: A New Africa’s Media Image?

Africa’s Media Image in the 21st Century is the first book in over twenty years to examine the international media’s coverage of sub-Saharan Africa. It brings together leading researchers and prominent journalists to explore representation of the continent, and the production of that image, especially by international news media. The book highlights factors that have transformed the global media system, changing whose perspectives are told and the forms of media that empower new voices. This introductory chapter by the book editors assesses Africa’s changing media image, examines the new image-makers, and reviews the geopolitics impacting upon that image

A note on the ring current in Saturn's magnetosphere: Comparison of magnetic data obtained during the Pioneer-11 and Voyager-1 and -2 fly-bys

International audienceWe examine the residual (measured minus internal) magnetic field vectors observed in Saturn's magnetosphere during the Pioneer-11 fly-by in 1979, and compare them with those observed during the Voyager-1 and -2 fly-bys in 1980 and 1981. We show for the first time that a ring current system was present within the magnetosphere during the Pioneer-11 encounter, which was qualitatively similar to those present during the Voyager fly-bys. The analysis also shows, however, that the ring current was located closer to the planet during the Pioneer-11 encounter than during the comparable Voyager-1 fly-by, reflecting the more com-pressed nature of the magnetosphere at the time. The residual field vectors have been fit using an adaptation of the current system proposed for Jupiter by Connerney et al. (1981a). A model that provides a reasonably good fit to the Pioneer-11 Saturn data extends radially between 6.5 and 12.5 RS (compared with a noon-sector magnetopause distance of 17 RS), has a north-south extent of 4 RS, and carries a total current of 9.6 MA. A corresponding model that provides a qualitatively similar fit to the Voyager data, determined previously by Connerney et al. (1983), extends radially between 8 and 15.5 RS (compared with a noon-sector magnetopause distance for Voyager-1 of 23?24 RS), has a north-south extent of 6 RS, and carries a total current of 11.5 MA

Identification of generic study areas for the disposal of low level radioactive waste : western North Atlantic Ocean

There is a growing need to effectively dispose of the low level radioactive waste presently accumulating in the United States. It may be decided to "dump" radioactive contamination products onto the deep sea floor (within 200 miles of the U.S.) in accordance with present IAEA guidelines (see Appendix A) for ocean dumping of low level waste; in the event of such a decision suitable areas must be identified and carefully studied to determine the subsequent influence of the waste on the environment. Using the site suitability criteria mentioned above we have identified two areas of possible use for low level waste disposal, one north of Puerto Rico and one east of Cape Hatteras, as deserving further study. The following report describes the relevant physical and geological characteristics of these two areas that may be important in considering a dumping operation. We have also made some recommendations for confirmatory research. The Hatteras Abyssal Plain, lying close to the 200 mile limit, appears to be a viable region for the focus of future research efforts.Prepared for the Sandia Laboratories

Interpreting biological degradative processes acting on mammalian hair in the living and the dead: which ones are taphonomic?

Although the taphonomic (post-mortem) degradation processes relevant to teeth and bones have been well described, those taking place with regards to mammalian hairs have not been characterized to the same extent. This present article describes, in detail, microscopic changes resulting from the actions of biological agents that digest and degrade hairs. The most noteworthy and prevalent agents responsible for the destruction of hair structure are fungi, which use a range of strategies to invade and digest hairs. One of the most important finds to emerge from this study is that taphonomic structures and processes can easily be interpreted by the unwary as ‘real’, or as class characteristics for a particular animal taxon. Moreover, under certain conditions, ‘taphonomic’ processes normally associated with the dead are also present on the hairs of the living. This work will improve the reliability of hair examinations in forensic, archaeological and palaeontological applications—in addition, the finding has relevance in the protection of mammalian collections susceptible to infestation. This article also addresses the popular myth that ancient peoples were often red-haired and discusses phenomena responsible for this observation. Insights gained from detailed characterization of taphonomic processes in 95 hairs from a variety of species demonstrate the range and breadth of degradative effects on hair structure and colour. Lastly, the study demonstrates that hairs often tell a story and that there is value of extracting as much morphological data as possible from hairs, prior to destructive sampling for biomolecules