Health impacts of wind turbines

This report presents the results of a rapid, desk based analysis of peer reviewed UK and international literature from the last four years on the effects of wind turbines on human health. The review covers literature specified by the Scottish government, peer-reviewed original studies and recent peer-reviewed literature reviews. Recent original studies consist mostly of cross-sectional studies and case studies on the effects of wind turbines on local residents. All studies present evidence for annoyance due to wind turbine noise and most concur that there is evidence for sleep disturbance in the presence of wind farms but not necessarily from noise. Both results are in agreement with the effects of noise from other environmental sources. Other health effects are increasingly reported in the presence of wind turbines but the reviewed literature does not provide firm scientific evidence of a causal relationship with wind turbines or even more specifically wind turbine noise. The most widely quoted cross-sectional studies show correlations between annoyance and visual impact, economic benefit and attitude related to wind turbines. Wind turbine sound is reported to be comparatively weakly related to annoyance and inseparable from the other contributing factors. Literature on low frequency noise and infrasound (LFIS) can be categorised as reviews, sound level measurements around windfarms and discussion of mechanisms of perception and response. A Swedish review finds no evidence to support ‘wind turbine syndrome’ while another concludes that further research is required. Regarding noise measurements, there are concerns that a new generation of wind turbines will produce a sound with a spectrum shifted down in frequency. However, a study in Australia concluded that infrasound levels near windfarms were no higher than elsewhere and that higher levels in urban areas were probably due to traffic and other human activity rather than wind turbines. Some other studies found measured sound levels near wind farms to conform with a range of criteria for LFIS. Papers by Salt et al. propose that LFIS may differentially stimulate structures in the human inner ear, and may instigate health effects even when inaudible. The authors seek to build a speculative case utilising experimental data gleaned from guinea pigs and some observations on human experiences with specific pathological conditions. Based upon the documents submitted, the proposal is unproven, and would need clear data from hypothesis driven independent research in humans in order to be credible. A proposal by US consultants that motion sickness-like symptoms reported at one wind farm might be caused by acoustic excitation of the balance organs is not new and has previously been discounted as an explanation for similar reported effects not involving wind turbines. Other evidence on acoustic stimulation of the balance organs has been noted but not reviewed. Health effects from other wind turbine related sources such as shadow flicker have been reported in several studies and guidelines to be less of a problem. Careful wind farm design and operational restrictions are suggested to be sufficient to minimise the impact. The mitigation strategies have been found to vary widely internationally with some countries and federal states using fixed noise limits, others using noise limits relative to existing background levels and many like the UK using a combination of both. Set-back distances are also used internationally but have a number of disadvantages. The relevant UK guideline document ETSU-R-97 aims to provide a reasonable degree of protection to noise sensitive listeners; without unduly restricting the development of wind turbine renewable energy resources. In the international comparison the ETSU-R-97 guidelines tends to result in comparatively low noise limits although direct comparisons between fixed and relative noise limits are difficult. ETSU-R-97 has been criticised for its inconsistent implementation and relative complexity. Good practice guidelines by the Institute of Acoustics which aim to address the implementation issues are due to be published in May

The case for new academic workspaces

Executive summary: This report draws upon the combined efforts of a number of estates professionals, architects, academics, designers, and senior managers involved in the planning of new university buildings for the 21st century. Across these perspectives, all would agree – although perhaps for different reasons - that this planning is difficult and that a number of particular considerations apply in the design of academic workspaces. Despite these difficulties, they will also agree that when this planning goes well, ‘good’ buildings are truly transformational – for both the university as a whole and the people who work and study in them. The value of well-designed buildings goes far beyond their material costs, and endures long after those costs have been forgotten ..

Factors associated with success in guide dog training

Tests of motor laterality and behavioral reactivity, as well as salivary cortisol concentrations, were examined in this pilot study to identify dogs best suited to guide dog work. Over a 14-month period, lateralization tests were conducted and cortisol concentrations were determined on 3 separate occasions, and temperament testing was performed on 2. Potential guide dogs (N = 43) involved in this study were 5 golden retrievers (4 males, 1 female) and thirty-eight Labrador retrievers (8 black males, fifteen yellow males, 5 black females, and ten yellow females). Results from these tests were then compared with the ultimate success of the dogs in the Guide Dogs NSW/ACT training program. This comparison produced evidence that motor lateralization (particularly the rate at which both paws were used during the Kong Test and the lateralization index during the Tape Test), reactions to an unfamiliar dog, the latency for dogs to drop and rest during an uninterrupted period, and the dog\u27s color and breed were predictive of ultimate success. This study also identified 14 months of age as a more accurate time to assess dogs for these traits than either 6 months of age or at the age at which they completed their training (ranging from 14 to 20 months of age)

Size and emotion or depth and emotion? Evidence, using Matryoshka (Russian) dolls, of children using physical depth as a proxy for emotional charge

Background: The size and emotion effect is the tendency for children to draw people and other objects with a positive emotional charge larger than those with a negative or neutral charge. Here we explored the novel idea that drawing size might be acting as a proxy for depth (proximity).Methods: Forty-two children (aged 3-11 years) chose, from 2 sets of Matryoshka (Russian) dolls, a doll to represent a person with positive, negative or neutral charge, which they placed in front of themselves on a sheet of A3 paper. Results: We found that the children used proximity and doll size, to indicate emotional charge. Conclusions: These findings are consistent with the notion that in drawings, children are using size as a proxy for physical closeness (proximity), as they attempt with varying success to put positive charged items closer to, or negative and neutral charge items further away from, themselves

Chlamydial conjunctivitis presenting as pre septal cellulitis

Chlamydia conjuctivitis results from infection by chlamydia trachomatis, the commonest treatable sexually transmitted infection in Europe. Its clinical manifestations involve the conjunctiva and the cornea. The inflammation under the upper eyelid may be sufficient to present as ptosis, however previously it has not been documented to cause a preseptal cellulitis. We present such a case. A 15-year-old girl was diagnosed with a left viral conjunctivitis. Five days later, she returned with marked oedema of the left upper and lower lids accompanied by erythema. The tarsal conjunctiva revealed follicles and large papillae and extra ocular movements revealed discomfort on elevation. A secondary diagnosis of bacterial pre septal cellulitis was made and the treatment was changed a broad spectrum oral antibiotic. On review at two days, the patient now complained of a large amount of purulent discharge in association with the marked pre septal swelling. As previous bacteriology and virology had been negative, the patient was re swabbed for chlamydia. This proved positive and her symptoms completely resolved following administration of Azithromycin. In this particular case recognition of the pathogen is important to alert the patient to the likelihood of unknown genital infestation. In all cases of positive culture, the patient should be counselled to attend a genitourinary clinic and to alert any sexual partners to the need to do likewise

Cell cycle times of short-term cultures of brain cancers as predictors of survival

Tumour cytokinetics estimated in vivo as potential doubling times (Tpot values) have been found to range in a variety of human cancers from 2 days to several weeks and are often related to clinical outcome. We have previously developed a method to estimate culture cycle times of short-term cultures of surgical material for several tumour types and found, surprisingly, that their range was similar to that reported for Tpot values. As Tpot is recognised as important prognostic variable in cancer, we wished to determine whether culture cycle times had clinical significance. Brain tumour material obtained at surgery from 70 patients with glioblastoma, medulloblastoma, astrocytoma, oligodendroglioma and metastatic melanoma was cultured for 7 days on 96-well plates, coated with agarose to prevent proliferation of fibroblasts. Culture cycle times were estimated from relative 3H-thymidine incorporation in the presence and absence of cell division. Patients were divided into two groups on the basis of culture cycle times of ⩽10 days and >10 days and patient survival was compared. For patients with brain cancers of all types, median survival for the ⩽10-day and >10-day groups were 5.1 and 12.5 months, respectively (P=0.0009). For 42 patients with glioblastoma, the corresponding values were 6.5 and 9.0 months, respectively (P=0.03). Lower grade gliomas had longer median culture cycle times (16 days) than those of medulloblastomas (9.9 days), glioblastomas (9.8 days) or melanomas (6.7 days). We conclude that culture cycle times determined using short-term cultures of surgical material from brain tumours correlate with patient survival. Tumour cells thus appear to preserve important cytokinetic characteristics when transferred to culture