248 research outputs found

    An overview on leveraging social media technology for uncovering tacit knowledge sharing in an organizational context

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    Over the years, businesses have transformed from the traditional manufacturing-oriented to service-oriented. Along with this, tacit knowledge has become more crucial as organizations move toward innovation and service orientation. In summary, the knowledge of an organization's workforce is tacit knowledge related to their belief and expertise, which can be difficult to define, given its inexpressible characteristics. The practice of knowledge management is often associated with the use of information systems and the effort to codify, share and create knowledge using relevant knowledge management systems. Although social media is widely adopted by organizations to enhance the effectiveness of knowledge sharing practices, there is still a large amount of uncertainty on whether information systems act as an environment for the sharing of tacit knowledge. The purpose of this study is to understand the significant role of social media in offering tacit knowledge. Wiki, because of its collaborative and conversational bases, was chosen as an example of a social media and the methodology undertaken in this study is literature review. This study contributes to a discussion on the increasingly important role of social media in the dissemination of tacit knowledge in an organizational context

    Long-term subjective cognitive functioning following adjuvant systemic treatment:7-9 years follow-up of a nationwide cohort of women treated for primary breast cancer

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    BACKGROUND: There is growing concern among breast cancer (BC) patients and survivors about cognitive impairment following systemic treatments. The aim of the present study was to investigate the long-term effects of standard systemic adjuvant therapies on subjective cognitive impairment (SCI) in a large nationwide cohort of BC survivors 7–9 years after primary surgery. METHODS: Participants were recruited from the nationwide Psychosocial Factors and Breast Cancer inception cohort of Danish women treated for primary BC. SCI was assessed with the Cognitive Failures Questionnaire and women allocated to systemic treatment according to nationwide standard protocols were compared with women who had not received any systemic treatments. RESULTS: A total of 1889 recurrence-free survivors were eligible for analysis. No difference in SCI was found between survivors across standardized systemic treatment protocols when analyses were stratified by menopausal status and adjusted for possible sociodemographic and treatment-related confounders. The frequency of significant SCI in a subgroup of survivors in the age range 65–74 years was ∼7%. CONCLUSIONS: No differences in long-term SCI at 7–9 years post surgery were found between women who had received systemic therapies and those who had not. Furthermore, the observed proportion of survivors with significant SCI was comparable to normative data. These results are important to communicate to patients, survivors, and clinicians alike, especially in the light of increasing concern about cognitive impairment following systemic therapies

    Bi-objective optimization model for optimal placement of thyristor-controlled series compensator devices

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    Exposure to extreme weather conditions increases power systems’ vulnerability in front of high impact, low probability contingency occurrence. In the post-restructuring years, due to the increasing demand for energy, competition between electricity market players and increasing penetration of renewable resources, the provision of effective resiliency-based approaches has received more attention. In this paper, as the major contribution to current literature, a novel approach is proposed for resiliency improvement in a way that enables power system planners to manage several resilience metrics efficiently in a bi-objective optimization planning model simultaneously. For demonstration purposes, the proposed method is applied for optimal placement of the thyristor controlled series compensator (TCSC). Improvement of all considered resilience metrics regardless of their amount in a multi-criteria decision-making framework is novel in comparison to the other previous TCSC placement approaches. Without loss of generality, the developed resiliency improvement approach is applicable in any power system planning and operation problem. The simulation results on IEEE 30-bus and 118-bus test systems confirm the practicality and effectiveness of the developed approach. Simulation results show that by considering resilience metrics, the performance index, importance of curtailed consumers, congestion management cost, number of curtailed consumers, and amount of load loss are improved by 0.63%, 43.52%, 65.19%, 85.93%, and 85.94%, respectively

    Computerized cognitive training in prostate cancer patients on androgen deprivation therapy: a pilot study

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    © 2017, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: Prostate cancer patients who have undergone androgen deprivation therapy (ADT) may experience cognitive impairment, yet there is an unmet need for nonpharmacological interventions to address cognitive impairment in this population. This study examines the feasibility, acceptability, and preliminary efficacy of a home-based computerized cognitive training (CCT) program to treat cancer-related cognitive impairment. Methods: Sixty men who had received ≥ 3 months of ADT were screened for at least mild cognitive or neurobehavioral impairment and randomized to 8 weeks of CCT or usual care. Follow-up assessments occurred immediately post-intervention or equivalent (T2) and 8 weeks later (T3). The acceptability of CCT was also assessed. Results: Feasibility:A priori feasibility thresholds were partially met (i.e., randomization rate \u3e 50%, retention rate \u3e 70% excluding CCT drop-outs, but \u3c 70% for intent-to-treat). Acceptability: Participants were mostly satisfied with CCT and found it somewhat enjoyable, though barriers to uptake existed. Preliminary efficacy: Linear mixed models indicated significant time by group effects favorable to CCT in reaction time (p =.01), but unfavorable to CCT in verbal and visual memory (ps \u3c .05). Memory was temporarily suppressed in the CCT group at T2, but normalized by T3. There was no effect of CCT on self-reported cognitive functioning, neurobehavioral functioning, nor quality of life. Conclusions: This study provides tentative support for the feasibility and acceptability of CCT to treat mild cognitive impairment in ADT patients. CCT had a beneficial effect on reaction time, but temporarily suppressed memory. CCT’s benefits may be limited to a narrow area of functioning. Larger-scale studies are needed

    Overview of knowledge flow in a software development process

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    Knowledge flow (KF) and workflow have many definitions in the literature. The development of information technology has led many organizations to become more focused on knowledge than on labor because KF is considered complementary to the software development process when used in the software development domain. Knowledge is the most valuable property about any business organization or academic institution; in addition the knowledge flow plays a part in elevating the competitiveness of teams. This paper presents the origin of KF research and its different definitions. It provides an overview of KF and workflow and the interaction mechanism between the two. A systematic review of the subject is also given

    Supplementation of freezing and thawing media with brain-derived neurotrophic factor protects human sperm from freeze-thaw-induced damage

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    Objective To investigate the effects of brain-derived neurotrophic factor (BDNF) supplementation to freezing and thawing media on frozen-thawed human sperm parameters. Design Laboratory study. Setting University hospital. Patient(s) Semen samples from 21 healthy fertile men. Intervention(s) We measured reactive oxygen species (ROS) by flow cytometry using the probes dichlorofluorescin diacetate for intracellular hydrogen peroxide (H2O2) and dihydroethidium for intracellular superoxide anion (O2��), sperm plasma membrane integrity by flow cytometry, caspase-3 activity using ELISA, and AKT phosphorylation status using Western blot in sperm that was cryopreserved and thawed in media either supplemented with BDNF or without BDNF supplementation (control). Main Outcome Measure(s) Sperm motility, viability, ROS levels, caspase-3 activity and AKT phosphorylation. Result(s) The percentage of motile and viable sperm cells was significantly higher in BDNF-supplemented groups as compared with the nonsupplemented (control) group. There was a significant difference in AKT phosphorylation status between BDNF-supplemented groups and the control group. Moreover, the levels of intracellular H2O2 and caspase-3 activity were significantly lower in the sperm cells that were frozen and thawed in media supplemented with BDNF compared with in the control group. Conclusion(s) BDNF supplementation to sperm freezing or thawing media has protective effects against oxidative stress and apoptosis in frozen-thawed human spermatozoa and could improve sperm function, probably through the activation of AKT. © 2016 American Society for Reproductive Medicin

    Measurement of the WW Boson Mass

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    A measurement of the mass of the WW boson is presented based on a sample of 5982 WeνW \rightarrow e \nu decays observed in ppp\overline{p} collisions at s\sqrt{s} = 1.8~TeV with the D\O\ detector during the 1992--1993 run. From a fit to the transverse mass spectrum, combined with measurements of the ZZ boson mass, the WW boson mass is measured to be MW=80.350±0.140(stat.)±0.165(syst.)±0.160(scale)GeV/c2M_W = 80.350 \pm 0.140 (stat.) \pm 0.165 (syst.) \pm 0.160 (scale) GeV/c^2.Comment: 12 pages, LaTex, style Revtex, including 3 postscript figures (submitted to PRL

    Search for a Fourth Generation Charge -1/3 Quark via Flavor Changing Neutral Current Decay

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    We report on a search for pair production of a fourth generation charge -1/3 quark (b') in pbar p collisions at sqrt(s) = 1.8 TeV at the Fermilab Tevatron using an integrated luminosity of 93 pb^-1. Both quarks are assumed to decay via flavor changing neutral currents (FCNC). The search uses the signatures gamma + 3 jets + mu-tag and 2 gamma + 2 jets. We see no significant excess of events over the expected background. We place an upper limit on the production cross section times branching fraction that is well below theoretical expectations for a b' quark decaying exclusively via FCNC for b' quark masses up to m(Z) + m(b).Comment: Eleven pages, two postscript figures, submitted to Physical Review Letter
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