9 research outputs found

    Comparative Chemical Analysis, Phytochemical Screening and Antimicrobial Activities of the Rinds, Seeds and Juice of (Passiflora edulis var. flavicarpa) Passion Fruit

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    In this study, an attempt had been made to determine the proximate composition and anti-nutritional factors of the juice, rind and seed of passiflora edulis var. flavicarpa. Crude lipid was determined by Soxhlet extraction, crude protein by microkjeldahl method and crude carbohydrate by difference. The result of proximate composition showed that there was a significant difference (p<0.05) in fibre, protein, lipid, and moisture content between the rind, juice and seed.  The oxalate, phytate, tannin and cyanide content of the rind, seed and juice were low but differed significantly. The methanol extract of the rind, seed and juice of Passiflora edulis var. flavicarpa were screened for the presence of secondary plant metabolites and tested for antimicrobial activity. Flavonoids, alkaloids, volatile oils and balsam were detected in all the extracts. Saponins and steroids were detected in seed and juice extracts. Glycosides and saponin glycosides were detected in seed and peel extracts. The antibacterial activity was tested against Salmonella typhi, Escherichia coli and Staphylococcus aureus by well-in agar method. The rind and seed showed significant antibacterial activity against the test organisms at all the concentrations tested (30, 60 and 90 mg/ml). The juice extract showed moderate activity. The rind, seed and juice showed antifungal activity. The fungus isolate used was Aspergillus niger using agar incorporation method. The methanol extracts of seed and rind showed extremely significant differences (p<0.05) against the Aspergillus niger, while juice extract considered not quite significant (p>0.05). The result showed a significant increase in the activity of the extracts at all the concentrations tested (10, 20, 40, 70 and 100 mg/ml). The observed result may be attributed to the presence of detected phytochemical constituents. It can be concluded that Passiflora edulis var. flavicarpa possess antimicrobial activity and is also nutritionally relevant and could serve as a rich source of nutrients. Keywords: Passiflora edulis var. flavicarpa, Comparative, Chemical, Antinutritional. Phytochemical, antimicrobial

    Suicide risk among psychiatric in-patients in north-central Nigeria

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    Background: Over the last 45 years, mortality due to suicide has increased in some developed and developing countries among both adults and young people. Suicide has also been reported to be high for individuals with substance abuse, mood and personality disorders, and relatively low rates were reported for patients with anxiety disorders. This study was therefore to determine the socio-demographic and clinical factors associated with the risk of suicide among psychiatric in-patients in North-Central Nigeria.Objective: The aim of this study is to look at the socio-demographic and clinical correlates of having suicide risk among psychiatric in-patients.Method: This is a cross-sectional descriptive study conducted on 112 in-patients admitted in the psychiatric wards of BSUTH Makurdi, FMC Makurdi and JUTH Jos during the study period of July to September, 2017. Every consecutive in-patient who consented for the study was assessed with a proforma carefully designed bythe authors to measure socio-demographic and clinical attributes. Suicide risk was determined using the 'Suicidality Module' of Mini International Neuropsychiatric Interview (M.I.N.I.).Results: Forty-five (40.2%) were males while 67(59.8%) were females. The mean age was 36.98 ±11.09 years, fifty- four (48.2%) subjects were still married at the time of the study. Eighty subjects representing 71.4% of the respondents reported having low (46), moderate (16) or high (18) suicide risk. Having a risk of suicide was significantly associated with the history of default (p=0.001), previous episodes of illness (p=0.005), co-morbid diagnosis (p=0.001), long duration of illness (p=0.001), and not having a good relationship with sexual partner (p=0.002).Conclusion: The study justifies the need for the assessment of suicide risk among in-patients with high degree of suspicion.Keywords: Suicide risk, in-patient, correlate

    Estas son algunas de las habilidades blandas demandadas en Colombia

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    Este producto forma parte de una serie de infografías de divulgación científica que buscan reseñar algunas de las investigaciones más importantes en las que ha tenido participación la Universidad EAFIT, publicadas en las revistas especializadas más prestigiosas del mund
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