Synthesis and Environmental Application of BiOI/BiOCl Composites

This work illustrates an enhanced visible light photocatalytic degradation of methyl orange dye (M.O.) by employing BiOI / BiOCl composites prepared under room temperature and without any organic precursors. Various experimental parameters have been studied, namely; composition of the composite, irradiation time and cell material. Composition D which implied 75% BiOI and 25% BiOCl has shown the highest bleaching of M.O. dye. This confirms the optimum photo-sensitization phenomenon for this composition in comparison to others. In the optimum photo-sensitized composite the electron of the conduction band reveals better reducing power and the hole of the valence band exhibits more oxidative power than those of pure BiOI electron and hole. Accordingly, under appropriate experimental conditions, methyl orange was significantly bleached using composite D

Impaired aortic distensibility measured by computed tomography is associated with the severity of coronary artery disease.

Impaired aortic distensibility index (ADI) is associated with cardiovascular risk factors. This study evaluates the relation of ADI measured by computed tomographic angiography (CTA) with the severity of coronary atherosclerosis in subjects with suspected coronary artery disease (CAD). Two hundred and twenty-nine subjects,age 63 ± 9 years, 42% female, underwent coronary artery calcium (CAC) scanning and CTA, and their ADI and Framingham risk score (FRS) were measured. End-systolic and end-diastolic (ED) cross-sectional-area(CSA) of ascending-aorta (AAo) was measured 15-mm above the left-main coronary ostium. ADI was defined as: [(Δlumen-CSA)/(lumen-CSA in ED × systemic-pulse-pressure) × 10(3)]. ADI measured by 2D-trans-thoracic echocardiography (TTE) was compared with CTA-measured ADI in 26 subjects without CAC. CAC was defined as 0, 1-100, 101-400 and 400+. CAD was defined as luminal stenosis 0, 1-49% and 50%+. There was an excellent correlation between CTA- and TTE-measured ADI (r(2)=0.94, P=0.0001). ADI decreased from CAC 0 to CAC 400+; similarly from FRS 1-9% to FRS 20% + (P<0.05). After adjustment for risk factors, the relative risk for each standard deviation decrease in ADI was 1.66 for CAC 1-100, 2.26 for CAC 101-400 and 2.32 for CAC 400+ as compared to CAC 0; similarly, 2.36 for non-obstructive CAD and 2.67 for obstructive CAD as compared to normal coronaries. The area under the ROC-curve to predict significant CAD was 0.68 for FRS, 0.75 for ADI, 0.81 for CAC and 0.86 for the combination (P<0.05). Impaired aortic distensibility strongly correlates with the severity of coronary atherosclerosis. Addition of ADI to CAC and traditional risk factors provides incremental value to predict at-risk individuals

Magnetic Deflection Coefficient Investigation for Low Energy Particles

In this research we solved numerically Boltzmann transport equation in order to calculate the transport parameters, such as, drift velocity, W, D/? (ratio of diffusion coefficient to the mobility) and momentum transfer collision frequency ?m, for purpose of determination of magnetic drift velocity WM and magnetic deflection coefficient ? for low energy electrons, that moves in the electric field E, crossed with magnetic field B, i.e; E×B, in the nitrogen, Argon, Helium and it's gases mixtures as a function of: E/N (ratio of electric field strength to the number density of gas), E/P300 (ratio of electric field strength to the gas pressure) and D/? which covered a different ranges for E/P300 at temperatures 300°k (Kelvin). The results showed had been tabulated and graphically represented as functions of their variables. These results a satisfactory agreement between experimental values and theoretical data given in the literature showed

Properties of High Strength Concrete Containing StonePowder as Natural Pozzolanic Materials

Currently high-strength concrete is increasingly used in modern concrete technology and particularly in the construction of high rise buildings. This study has been conducted to investigate the properties of high-strength concrete that was produced by using stone powder (SP) as an alternative of proportion on cement after being processed , since its main oxides are similar to those of cement. The aim of the research is to study the effect of (10,15,20,25)% stone powder as replacement of cement, used in concrete mix which it has a mixing proportion of (1:2:1.8;w/c=0.26), and it is shown their effect on some of mechanical properties(compressive strength, splitting tensile strength, and flexural strength). The test results showed clear improvement in some mechanical properties of concrete by using 20% (SP). The increment where its ratio (34, 41, 34.4)% for each compressive strength, splitting tensile strength, and flexural strength compared with reference mixture for the same duration respectively

The Influence of Age and Cardiorespiratory Fitness on Cardiac Autonomic Modulation. A Pilot Study.

Maximal rate of oxygen consumption (VO2max) is traditionally viewed as the gold standard of determining cardiorespiratory fitness (CF) in healthy and diseased populations. CF has a significant influence on the improvement of cardiac autonomic modulation (CAM) and the risk of morbidity and mortality rates. Heart rate variability (HRV) is a non-invasive way to assess CAM. Age is another factor that influences CAM and CF in healthy and diseased populations. However, what is not fully elucidated, is if CF is maintained at a high level throughout adulthood, will CAM remain relatively unchanged. PURPOSE: To determine if age and CF are significantly correlated to variables of HRV to determine CAM in healthy fit individuals. METHODS: Twenty-two healthy individuals (n = 14 male; n = 8 female, Age 33.2 ± 11.8 years, %BF 18.3 ± 6.0, VO2max 42.0 ± 6.2 ml/ /kg/min) completed a single health assessment to quantify CF and HRV. HRV was measured for 5 mins in the supine position and during a standard VO2max test using an elastic belt and Bluetooth monitor (Polar H7). CardioMood software was used to process HRV variables high frequency (HF), low frequency (LF), total power (TP) were assessed for frequency domain, and standard deviation of all NN intervals (SDNN) and the square root of the mean of the squares of successive R-R interval differences (RMSSD) for the time domain. Pearson correlation was used to check associations between age and CF, and CAM. Multiple regression was implemented to determine if there were any differences in HRV variables in relation to age and VO2max. A paired sample t-test was used to determine changes in HRV variables from rest to VO2max. All analyses were performed using SAS (v.9.3). RESULTS: HRV variables were significantly altered from rest to VO2max (p \u3c 0.05). HRV time and frequency domain variables were not significantly correlated to age and CF level (p \u3e 0.05). The multiple regression analysis indicated that the only significance was max heart rate is 0.642 bpm lower during exercise for each 1-year increase in age (p = 0.035). CONCLUSION: The analysis of pilot data focused on determining the impact of CF and age on CAM appears not to be significantly correlated when utilizing HRV. However, due to the project\u27s continuation and further data collection, significant outcomes may still be observed

Do drivers self-regulate their engagement in secondary tasks at intersections? An examination based on naturalistic driving data

Using naturalistic driving data, this study explored the prevalence of engagement in secondary tasks whilst driving through intersections, and investigated whether drivers manage and self-regulate such behaviour in response to variations in roadway and environmental conditions. Video recordings of in-vehicle and external scenes were coded for precisely defined categories of secondary tasks and related contextual variables. The findings indicated that nearly one-quarter of the total driving time at intersections was spent on secondary activities and that lower engagement occurred within intersections compared to phases immediately upstream or downstream. Drivers were less likely to occupy themselves with secondary tasks when their vehicles were moving than when they were stationary. Elderly drivers showed less inclination to perform secondary tasks than did younger drivers. Lastly, drivers tended to perform secondary tasks less frequently at intersections managed by traffic signs than those controlled by traffic lights, when they did not have priority compared to when they had priority, and in adverse weather conditions compared to fine weather conditions. In conclusion, drivers appeared to self-regulate secondary task engagement in response to roadway and environmental conditions. Specifically, they exercised self-regulation by reducing their secondary task engagement when the driving task was more challenging. The findings from this study provide preliminary evidence for targeting the education and training of drivers and media campaigns related to safe driving strategies and managing distractions

Applicable Studies of the Slow Electrons Motion in Air with Application in the Ionosphere

In this study, the motions of slow electrons in air and nitrogen with it's mixtures are studies by details. We solved numerically Boltzmann transport equation to calculate the parameters E, Vd and D/m have been possible to deduce expression empirical formula from which may be derived the drift velocity, collisional frequencies, electronic temperature and mean energy loss per collision. These results applied to the ionosphere allow electronic collisional frequencies to be ready found in the ionosphere below 94 km, from the pressure of the air. The collision cross-sections of the molecules of air and nitrogen when the electronics temperature is less than about 2600°K. The addition results are presented for electrons drifting through air in a steady state of motion under the action of the electric field, such as, KT, U, Q, Q0, ω, ω/P,h, hKT , and W/D for both Maxwell and Druyvesteyn distribution laws. This parameters are graphically as a functions for their variables. The results appeared excellent agreements with the experiments and theoretical data

Association between Total Body Composition and VO2max in Individuals with Mid-Spectrum Chronic Kidney Disease

Total body composition (TBC), a measure of body fat percentage (%BF), lean body mass (LBM), and bone mineral content (BMC), can be used as a predictor of cardiovascular fitness. Prior studies have established a relationship between TBC and VO2max in healthy individuals over 35 years of age. However, this relationship is poorly understood in chronic disease populations. PURPOSE: To assess the relationship between TBC and cardiovascular fitness in a clinical population of adults with mid-spectrum (stages G2, G3a, and G3b) chronic kidney disease (CKD). METHODS: A cross-sectional analysis was conducted among 24 subjects diagnosed with mid-spectrum CKD. Nine males and 15 females with an average age of 62.25±9.2 years and a glomerular filtration rate (GFR) of 54.38±9.04 ml/min/1.73m2 completed the study. Subjects completed a health screening, dual-energy x-ray absorptiometry (DEXA) scan, and underwent VO2max testing on a treadmill using a modified Bruce protocol. Normality tests, descriptive statistics, Pearson’s correlations, t-tests, and ANOVAs were conducted in SAS v.9.4. RESULTS: The average %BF was 36.28±8.47%, LBM was 117.16±31.32lbs., BMC was 2308.74±735.19g., and VO2max was 20.13±5.04ml/kg/min. VO2max was positively correlated with BMC and LBM (r=0.65, p=0.001 and r=0.75, p\u3c0.001, respectively) and negatively correlated with %BF (r= -0.80, p\u3c0.001). Individuals in later stages of CKD had lower LBM, BMC, and VO2max (p=0.017, p=0.001, and p=0.007, respectively), yet there was no association of CKD stage with %BF or age (p=0.210 and p=0.107). CONCLUSION: TBC was found to be significantly associated with cardiovascular fitness in the study sample. Higher BMD and LBM values were associated with higher VO2max whereas higher %BF was associated with a lower VO2max in individuals with mid-spectrum CKD. Progression of CKD stage was associated with lower LBM, BMC, and VO2max values, indicating a graded effect of CKD stage on cardiovascular fitness

Is Age an Independent Factor in Assessing Renal Health and Function in Healthy Individuals? A Pilot Study

Estimated glomerular filtration rate (eGFR) is a measure of renal filtration and clearance of serum creatinine and is conventionally used to characterize the progressive decline in renal function. Assessment of renal function and health is traditionally believed to be age-dependent. However, in the absence of cardiometabolic diseases (hypertension, diabetes, hyperlipemia, etc.), this may not be the case. Recently, novel markers of renal health and function support the notion that age is a secondary factor influencing renal decline. PURPOSE: To determine the magnitude of age as an influencing factor involved in the decline of renal function with novel markers of renal health and function in the absence of cardiometabolic risk factors. METHODS: Thirty-nine participants (n = 18 men; n = 21 women; age 32.5 + 12.6 yr; height 171.1 + 11.4 cm; weight 78.7 + 15.6 kg; BMI 27.1 + 5.8; SBP 120 + 11.2; DBP 78 + 6.6; CHOL 173 + 30; and GLU 96 + 7) completed a single health assessment to quantify renal health and function. Blood and urine samples were collected by the same technician under standardized conditions and stored at -60 ºC until project completion. Serum creatinine (sCR), urine creatinine (uCr), urine epidermal growth factor (uEGF), uEGF/uCr ratio (uEGFR), cystatin C (CyC) and eGFR - modification of diet in renal disease (MDRD) and the CKD-EPI - responses were analyzed and compared in age groups (20s, 30s, 40s, 50s) using 4 (group) by 1 (sample) ANOVAs. RESULTS: There were no significant differences in markers of renal health and function between any age group. sCR (p = 0.90), uCr (p = 0.17), uEGF (p = 0.15), CyC (p = 0.32), uEGFR (p = 0.28), MDRD (p = 0.17), and CKD-EPI (p = 0.83). CONCLUSION: In healthy individuals, changes in renal health and function appear to be independent of age in the absence of cardiometabolic diseases. Indicating renal health and function could potentially be maintained throughout adulthood, middle age, and possibly attenuated in the senior years with the continued absence of cardiometabolic diseases

Comparative Outcomes of Commonly Used Off-Label Atypical Antipsychotics in the Treatment of Dementia-Related Psychosis: A Network Meta-Analysis

Introduction Dementia-related psychosis (DRP) is characterized by hallucinations and delusions, which may increase the debilitating effects of underlying dementia. This network meta-analysis (NMA) evaluated the comparative efficacy, safety, and acceptability of atypical antipsychotics (AAPs) commonly used off label to treat DRP. Methods We included 22 eligible studies from a systematic literature review of AAPs (quetiapine, risperidone, olanzapine, aripiprazole, and brexpiprazole) used off label to treat DRP. Study outcomes were: (1) efficacy—neuropsychiatric inventory-nursing home (NPI-NH psychosis subscale), (2) safety—mortality, cerebrovascular events (CVAEs), and others (somnolence, falls, fractures, injuries, etc.), and (3) acceptability—discontinuations due to all causes, lack of efficacy, and adverse events (AEs). We used random-effects modeling to estimate pooled standardized mean differences (SMDs) for NPI-NH psychosis subscale scores and odds ratios (OR) for other dichotomous outcomes, with their respective 95% confidence intervals (CIs). Results Compared with placebo, aripiprazole (SMD − 0.12; 95% CI − 0.31, 0.06), and olanzapine (SMD − 0.17; 95% CI − 0.04; 0.02) demonstrated small, non-significant numerical improvements in NPI-NH psychosis scores (5 studies; n = 1891), while quetiapine (SMD 0.04; 95% CI − 0.23, 0.32) did not improve symptoms. The odds of mortality (15 studies, n = 4989) were higher for aripiprazole (OR 1.58; 95% CI 0.62, 4.04), brexpiprazole (OR 2.22; 95% CI 0.30, 16.56), olanzapine (OR 2.21; 95% CI 0.84, 5.85), quetiapine (OR 1.68; 95% CI 0.70, 4.03), and risperidone (OR 1.63; 95% CI 0.93, 2.85) than for placebo. Risperidone (OR 3.68; 95% CI 1.68, 8.95) and olanzapine (OR 4.47; 95% CI 1.36, 14.69) demonstrated significantly greater odds of CVAEs compared to placebo. Compared with placebo, odds of all-cause discontinuation were significantly lower for aripiprazole (OR 0.71; 95% CI 0.51, 0.98; 20 studies; 5744 patients) and higher for other AAPs. Aripiprazole (OR 0.5; 95% CI 0.31, 0.82) and olanzapine (OR 0.48; 95% CI 0.31, 0.74) had significantly lower odds of discontinuation due to lack of efficacy (OR 12 studies; n = 4382) compared to placebo, while results for quetiapine and risperidone were not significant. Compared with placebo, the odds of discontinuation due to AEs (19 studies, n = 5445) were higher for olanzapine (OR 2.62; 95% CI 1.75, 3.92), brexpiprazole (OR 1.80; 95% CI 0.80, 4.07), quetiapine (OR 1.25; 95% CI 0.82, 1.91), aripiprazole (OR 1.38; 95% CI 0.90, 2.13), and risperidone (OR 1.41; 95% CI 1.02, 1.94). Conclusions Overall results demonstrate that, compared with placebo, quetiapine is not associated with improvement in psychosis in patients with dementia, while olanzapine and aripiprazole have non-significant small numerical improvements. These off-label AAPs (quetiapine, risperidone, olanzapine, aripiprazole, and brexpiprazole) are associated with greater odds of mortality, CVAEs, and discontinuations due to AEs than placebo. These results underscore the ongoing unmet need for newer pharmacological options with a more favorable benefit-risk profile for the treatment of DRP