A Multilayer Monte Carlo Model for the Investigation of Optical Path and Penetration Depth at Different Perfusion States of the Colon

There is a great interest in monitoring the oxygen supply delivered to the colon. Insufficient oxygen delivery may lead to hypoxia, sepsis, multiorgan dysfunction and death. For assessing colonic perfusion, more information and understanding is required relating to the light-interaction within the colonic tissue. A multilayer Monte Carlo model of a healthy human colon has been developed to investigate the light-tissue behavior during different perfusion states within the mucosal layer of the colon. Results from a static multilayer model of optical path and reflectance at two wavelengths, 660 nm and 880 nm, through colon tissue, containing different volume fractions of blood with a fixed oxygen saturation are presented. The effect on the optical path and penetration depth with varying blood volumes within the mucosa for each wavelength has been demonstrated. The simulation indicated both wavelengths of photons penetrated similar depths, entering the muscularis layer

Flux Tube Model Signals for Baryon Correlations in Heavy Ion Collisions

The flux tube model offers a pictorial description of what happens during the deconfinement phase transition in QCD. The 3-point vertices of a flux tube network lead to formation of baryons upon hadronisation. Therefore, correlations in the baryon number distribution at the last scattering surface are related to the preceding pattern of the flux tube vertices, and provide a signature of the nearby deconfinement phase transition. I discuss the nature of the expected signal, which should be observable in heavy ion collisions at RHIC and LHC.Comment: LaTeX, 9 pages, 5 figures, (v2) Several arguments expanded for clarity, (v3) Minor typesetting changes, published versio

The circulatory impact of dust from dust profile assimilation

We present results from a reanalysis of temperatures, dust columns and dust vertical profiles focussing on the assimilation, distribution and transport of dust in the martian atmosphere. The assimilation of dust vertical information in particular is a valuable technique which has been shown to be of vital importance to a successful assimilation of the martian atmosphere, with the vertical representation of the dust distribution having a critical effect on assimilation results generally. Atmospheric dust is a key driver of the martian circulation. Dust-induced heating and cooling is a potential feedback mechanism for dust lifting, for example, and can modify the circulation to either enhance or suppress dust storm activity. Accurately representing its complex spatial and temporal distribution is therefore crucial for understanding Mars’ atmospheric dynamics and transport

The Circumstellar Structure and Excitation Effects around the Massive Protostar Cepheus A HW 2

We report SMA 335 GHz continuum observations with angular resolution of ~0.''3, together with VLA ammonia observations with ~1'' resolution toward Cep A HW 2. We find that the flattened disk structure of the dust emission observed by Patel et al. is preserved at the 0.''3 scale, showing an elongated structure of ~$0.''6 size (450 AU) peaking on HW 2. In addition, two ammonia cores are observed, one associated with a hot-core previously reported, and an elongated core with a double peak separated by ~1.''3 and with signs of heating at the inner edges of the gas facing HW 2. The double-peaked ammonia structure, as well as the double-peaked CH3CN structure reported previously (and proposed to be two independent hot-cores), surround both the dust emission as well as the double-peaked SO2 disk structure found by Jimenez-Serra et al. All these results argue against the interpretation of the elongated dust-gas structure as due to a chance-superposition of different cores; instead, they imply that it is physically related to the central massive object within a disk-protostar-jet system.Comment: 12 pages, 3 figures; accepted for publication in the Astrophysical Journa

Interstitial cell network volume is reduced in the terminal bowel of ageing mice

Ageing is associated with impaired neuromuscular function of the terminal gastrointestinal (GI) tract, which can result in chronic constipation, faecal impaction and incontinence. Interstitial cells of cajal (ICC) play an important role in regulation of intestinal smooth muscle contraction. However, changes in ICC volume with age in the terminal GI tract (the anal canal including the anal sphincter region and rectum)have not been studied. Here, the distribution, morphology and network volume of ICC in the terminal GI tract of 3‐to 4‐month‐old and 26‐to 28‐month‐old C57BL/6mice were investigated. ICC were identified by immunofluorescence labelling of wholemount preparations with an antibody against c‐Kit. ICC network volume was measured by software‐based 3D volume rendering of confocal Z stacks. A significant reduction in ICC network volume per unit volume of muscle was measured in aged animals. No age‐associated change in ICC morphology was detected. The thickness of the circular muscle layer of the anal sphincter region and rectum increased with age, while that in the distal colon decreased. These results suggest that ageing is associated with a reduction in the network volume of ICC in the terminal GI tract, which may influence the normal function of these regions

Comprehensive User Engagement Sites (CUES) in Philadelphia: A Constructive Proposal

This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with the federal drug schedules, the authors visit some of the medical and public health issues vis-à-vis safe injection facilities (SIFs). Insite, a successful Canadian SIF, has been thoroughly researched as it represents a paradigm for which a Philadelphia CUES can expand upon. Also, the existing criticisms against SIFs are revisited while critically unpackaged and responded to in favor of the establishment. In the main section, the authors propose the layout and services of the upcoming CUES, much of which would be in congruent to Vancouver’s Insite. On the other hand, the CUES would be distinct from Insite, as the authors emphasize, in that it will offer an information center run by individuals in recovery and place additional emphasis on early education for young healthcare professionals by providing them a platform to work at the site. The paper will also briefly investigate the implementation of a CUES site under an ethical scope of the Harm Reduction Theory. Lastly, the authors recommend some strategic plans that the Philadelphia City government may consider employing at this crucial stage

Characteristic Study of Combined eects of MHD and Coriolis Force on Free Convection in a Rectangular Cavity with Isotropic and Anisotropic Porous Media

This investigation deals with the classic Rayleigh - Benard problem for a laminar, viscous, unsteady incompressible fluid flow heated from below is extended to three-dimensional convection in a nite geometry with isotropic and anisotropic porous media rotating with constant angular velocity and the magnetic eld is applied in the vertical direction. For the given physical set-up, governing partial differential equations are transformed to a set of non-dimensional ordinary differential equations using similarity transformation. This demands to apply Fourier series method to study the characteristic of velocity, temperature and concentration for the effect of Taylors number, Rayleigh number, Hartmanns number and Prandtl number for both anisotropic and isotropic porous media. The results of steam function and isotherms on various parameters have been discussed and found to be good agreement for the physical system