WKB-type Approximation to Noncommutative Quantum Cosmology

In this work, we develop and apply the WKB approximation to several examples of noncommutative quantum cosmology, obtaining the time evolution of the noncommutative universe, this is done starting from a noncommutative quantum formulation of cosmology where the noncommutativity is introduced by a deformation on the minisuperspace variables. This procedure gives a straightforward algorithm to incorporate noncommutativity to cosmology and inflation.Comment: Revtex4, 6 pages, no figure

Marketing Percolation

A percolation model is presented, with computer simulations for illustrations, to show how the sales of a new product may penetrate the consumer market. We review the traditional approach in the marketing literature, which is based on differential or difference equations similar to the logistic equation (Bass 1969). This mean field approach is contrasted with the discrete percolation on a lattice, with simulations of "social percolation" (Solomon et al 2000) in two to five dimensions giving power laws instead of exponential growth, and strong fluctuations right at the percolation threshold.Comment: to appear in Physica

High quality epitaxial thin films and exchange bias of antiferromagnetic Dirac semimetal FeSn

FeSn is a topological semimetal (TSM) and kagome antiferromagnet (AFM) composed of alternating Fe3Sn kagome planes and honeycomb Sn planes. This unique structure gives rise to exotic features in the band structures such as the coexistence of Dirac cones and flatbands near the Fermi level, fully spin-polarized 2D surface Dirac fermions, and the ability to open a large gap in the Dirac cone by reorienting the N\'eel vector. In this work, we report the synthesis of high quality epitaxial (0001) FeSn films by magnetron sputtering. Using FeSn/Py heterostructures, we show a large exchange bias effect that reaches an exchange field of 220 Oe at 5 K, providing unambiguous evidence of antiferromagnetism and strong interlayer exchange coupling in our films. Field cycling studies show steep initial training effects, highlighting the complex magnetic interactions and anisotropy. Importantly, our work provides a simple, alternative means to fabricate FeSn films and heterostructures, making it easier to explore the topological physics of AFM TSMs and develop FeSn-based spintronics.Comment: accepted by AP

Comparing interventions and exploring neural mechanisms of exercise in Parkinson disease: a study protocol for a randomized controlled trial

BACKGROUND: Effective treatment of locomotor dysfunction in Parkinson disease (PD) is essential, as gait difficulty is an early and major contributor to disability. Exercise is recommended as an adjunct to traditional treatments for improving gait, balance, and quality of life. Among the exercise approaches known to improve walking, tango and treadmill training have recently emerged as two promising therapies for improving gait, disease severity and quality of life, yet these two interventions have not been directly compared to each other. Prior studies have been helpful in identifying interventions effective in improving gait function, but have done little to elucidate the neural mechanisms underlying functional improvements. The primary objective of the proposed work is to compare the effects of three community-based exercise programs, tango, treadmill training and stretching, on locomotor function in individuals with PD. In addition, we aim to determine whether and how these interventions alter functional connectivity of locomotor control networks in the brain. METHODS/DESIGN: One hundred and twenty right-handed individuals with idiopathic PD who are at least 30 years of age will be assigned in successive waves to one of three community-based exercise groups: tango dancing, treadmill training or stretching (control). Each group will receive three months of exercise training with twice weekly one-hour group classes. Each participant will be evaluated at three time points: pre-intervention (baseline), post-intervention (3 months), and follow-up (6 months). All evaluations will include assessment of gait, balance, disease severity, and quality of life. Baseline and post-intervention evaluations will also include task-based functional magnetic resonance imaging (fMRI) and resting state functional connectivity MRI. All MRI and behavioral measures will be conducted with participants OFF anti-Parkinson medication, with behavioral measures also assessed ON medication. DISCUSSION: This study will provide important insights regarding the effects of different modes of exercise on locomotor function in PD. The protocol is innovative because it: 1) uses group exercise approaches for all conditions including treadmill training, 2) directly compares tango to treadmill training and stretching, 3) tests participants OFF medication, and 4) utilizes two distinct neuroimaging approaches to explore mechanisms of the effects of exercise on the brain. TRIAL REGISTRATION: ClinicalTrials.gov NCT01768832

Measuring the Stellar Masses of z~7 Galaxies with Spitzer Ultrafaint Survey Program (SURFS UP)

We present Spitzer/IRAC observations of nine $z'$-band dropouts highly magnified (2<mu<12) by the Bullet Cluster. We combine archival imaging with our Exploratory program (SURFS UP), which results in a total integration time of ~30 hr per IRAC band. We detect (>3sigma) in both IRAC bands the brightest of these high-redshift galaxies, with [3.6]=23.80+-0.28 mag, [4.5]=23.78+-0.25 mag, and (H-[3.6])=1.17+-0.32 mag. The remaining eight galaxies are undetected to [3.6]~26.4 mag and [4.5]~26.0 mag with stellar masses of ~5x10^7 M_sol. The detected galaxy has an estimated magnification of mu=12+-4, which implies this galaxy has an ultraviolet luminosity of L_1500~0.3 L*_{z=7} --- the lowest luminosity individual source detected in IRAC at z>7. By modeling the broadband photometry, we estimate the galaxy has an intrinsic star-formation rate of SFR~1.3 M_sol/yr and stellar mass of M~2x10^9 M_sol, which gives a specific star-formation rate of sSFR~0.7 Gyr^-1. If this galaxy had sustained this star-formation rate since z~20, it could have formed the observed stellar mass (to within a factor of ~2), we also discuss alternate star-formation histories and argue the exponentially-increasing model is unlikely. Finally, based on the intrinsic star-formation rate, we estimate this galaxy has a likely [C II] flux of = 10^{-17} erg/s/cm2.Comment: Accepted to ApJL. 6 pages, 3 figures, 2 table

Noncommutative Geometry and Cosmology

We study some consequences of noncommutativity to homogeneous cosmologies by introducing a deformation of the commutation relation between the minisuperspace variables. The investigation is carried out for the Kantowski-Sachs model by means of a comparative study of the universe evolution in four different scenarios: the classical commutative, classical noncommutative, quantum commutative, and quantum noncommutative. The comparison is rendered transparent by the use of the Bohmian formalism of quantum trajectories. As a result of our analysis, we found that noncommutativity can modify significantly the universe evolution, but cannot alter its singular behavior in the classical context. Quantum effects, on the other hand, can originate non-singular periodic universes in both commutative and noncommutative cases. The quantum noncommutative model is shown to present interesting properties, as the capability to give rise to non-trivial dynamics in situations where its commutative counterpart is necessarily static.Comment: 22 pages, 5 figures, substantial changes in the presentation, results are the same, to appear in Physical Review

Assessing the utilization of high-resolution 2-field HLA typing in solid organ transplantation.

HLA typing in solid organ transplantation (SOT) is necessary for determining HLA-matching status between donor-recipient pairs and assessing patients\u27 anti-HLA antibody profiles. Histocompatibility has traditionally been evaluated based on serologically defined HLA antigens. The evolution of HLA typing and antibody identification technologies, however, has revealed many limitations with using serologic equivalents for assessing compatibility in SOT. The significant improvements to HLA typing introduced by next-generation sequencing (NGS) require an assessment of the impact of this technology on SOT. We have assessed the role of high-resolution 2-field HLA typing (HR-2F) in SOT by retrospectively evaluating NGS-typed pre- and post-SOT cases. HR-2F typing was highly instructive or necessary in 41% (156/385) of the cases. Several pre- and posttransplant scenarios were identified as being better served by HR-2F typing. Five different categories are presented with specific case examples. The experience of another center (Temple University Hospital) is also included, whereby 21% of the cases required HR-2F typing by Sanger sequencing, as supported by other legacy methods, to properly address posttransplant anti-HLA antibody issues