76 research outputs found
Spectroscopic Discovery of the Broad-Lined Type Ic Supernova 2010bh Associated with the Low-Redshift GRB 100316D
We present the spectroscopic discovery of a broad-lined Type Ic supernova (SN
2010bh) associated with the nearby long-duration gamma-ray burst (GRB) 100316D.
At z = 0.0593, this is the third-nearest GRB-SN. Nightly optical spectra
obtained with the Magellan telescopes during the first week after explosion
reveal the gradual emergence of very broad spectral features superposed on a
blue continuum. The supernova features are typical of broad-lined SNe Ic and
are generally consistent with previous supernovae associated with low-redshift
GRBs. However, the inferred velocities of SN 2010bh at 21 days after explosion
are a factor of ~2 times larger than those of the prototypical SN 1998bw at
similar epochs, with v ~ 26,000 km/s, indicating a larger explosion energy or a
different ejecta structure. A near-infrared spectrum taken 13.8 days after
explosion shows no strong evidence for He I at 1.083 microns, implying that the
progenitor was largely stripped of its helium envelope. The host galaxy is of
low luminosity (M_R ~ -18.5 mag) and low metallicity (Z < 0.4 Z_solar), similar
to the hosts of other low-redshift GRB-SNe.Comment: 6 pages, 4 figures, 1 table, submitted to ApJ Letter
International Commercial Arbitration: Fifty Years After the New York Convention
a one-day conference held at the Dean Rusk Center on January 30, 2009. The event, co-sponsored by the Georgia Journal of International and Comparative Law, featured Gary Born as keynote speaker and other leaders in the field of international commercial arbitration including Robert Davidson, Executive Director of JAMS Arbitration Practice; William K. Slate, II, President, American Arbitration Association; and Anne Marie Whitesell, Former Secretary General of the ICC International Court of Arbitration
OLTARIS: On-Line Tool for the Assessment of Radiation in Space
The On-Line Tool for the Assessment of Radiation In Space (OLTARIS) is a World Wide Web based tool that assesses the effects of space radiation to humans in items such as spacecraft, habitats, rovers, and spacesuits. This document explains the basis behind the interface and framework used to input the data, perform the assessment, and output the results to the user as well as the physics, engineering, and computer science used to develop OLTARIS. The physics is based on the HZETRN2005 and NUCFRG2 research codes. The OLTARIS website is the successor to the SIREST website from the early 2000 s. Modifications have been made to the code to enable easy maintenance, additions, and configuration management along with a more modern web interface. Over all, the code has been verified, tested, and modified to enable faster and more accurate assessments. The next major areas of modification are more accurate transport algorithms, better uncertainty estimates, and electronic response functions. Improvements in the existing algorithms and data occur continuously and are logged in the change log section of the website
Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class
Tumor-infiltrating lymphocytes (TILs) have prognostic significance in many cancers, yet their roles in glioblastoma (GBM) have not been fully defined. We hypothesized TILs in GBM are associated with molecular alterations, histologies and survival
The stellar content of the Hamburg/ESO survey. V. The metallicity distribution function of the Galactic halo
We determine the metallicity distribution function (MDF) of the Galactic halo
by means of a sample of 1638 metal-poor stars selected from the Hamburg/ESO
objective-prism survey (HES). The sample was corrected for minor biases
introduced by the strategy for spectroscopic follow-up observations of the
metal-poor candidates, namely "best and brightest stars first". [...] We
determined the selection function of the HES, which must be taken into account
for a proper comparison between the HES MDF with MDFs of other stellar
populations or those predicted by models of Galactic chemical evolution. The
latter show a reasonable agreement with the overall shape of the HES MDF for
[Fe/H] > -3.6, but only a model of Salvadori et al. (2007) with a critical
metallicity for low-mass star formation of Z_cr = 10^{-3.4} * Z_Sun reproduces
the sharp drop at [Fe/H] ~-3.6 present in the HES MDF. [...] A comparison of
the MDF of Galactic globular clusters and of dSph satellites to the Galaxy
shows qualitative agreement with the halo MDF, derived from the HES, once the
selection function of the latter is included. However, statistical tests show
that the differences between these are still highly significant. [ABSTRACT
ABRIDGED]Comment: Accepted for publication in A&
Solar Energetic Particle Spectrum on 13 December 2006 Determined by IceTop
On 13 December 2006 the IceTop air shower array at the South Pole detected a
major solar particle event. By numerically simulating the response of the
IceTop tanks, which are thick Cherenkov detectors with multiple thresholds
deployed at high altitude with no geomagnetic cut-off, we determined the
particle energy spectrum in the energy range 0.6 to 7.6 GeV. This is the first
such spectral measurement using a single instrument with a well defined viewing
direction. We compare the IceTop spectrum and its time evolution with
previously published results and outline plans for improved resolution of
future solar particle spectra.Comment: To appear in Astrophysical Journal Letters, 6 pages, 4 figure
FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity
Natural History of Tuberculosis: Duration and Fatality of Untreated Pulmonary Tuberculosis in HIV Negative Patients: A Systematic Review
Background The prognosis, specifically the case fatality and duration, of untreated tuberculosis is important as many patients are not correctly diagnosed and therefore receive inadequate or no treatment. Furthermore, duration and case fatality of tuberculosis are key parameters in interpreting epidemiological data. Methodology and Principal Findings To estimate the duration and case fatality of untreated pulmonary tuberculosis in HIV negative patients we reviewed studies from the pre-chemotherapy era. Untreated smear-positive tuberculosis among HIV negative individuals has a 10-year case fatality variously reported between 53% and 86%, with a weighted mean of 70%. Ten-year case fatality of culture-positive smear-negative tuberculosis was nowhere reported directly but can be indirectly estimated to be approximately 20%. The duration of tuberculosis from onset to cure or death is approximately 3 years and appears to be similar for smear-positive and smear-negative tuberculosis. Conclusions Current models of untreated tuberculosis that assume a total duration of 2 years until self-cure or death underestimate the duration of disease by about one year, but their case fatality estimates of 70% for smear-positive and 20% for culture-positive smear-negative tuberculosis appear to be satisfactory
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