Comparison of data on Mutation Frequencies of Mice Caused by Radiation - Low Dose Model -

We propose LD(Low Dose) model, the extension of LDM model which was proposed in the previous paper [Y. Manabe et al.: J. Phys. Soc. Jpn. 81 (2012) 104004] to estimate biological damage caused by irradiation. LD model takes account of all the considerable effects including cell death effect as well as proliferation, apoptosis, repair. As a typical example of estimation, we apply LD model to the experiment of mutation frequency on the responses induced by the exposure to low levels of ionizing radiation. The most famous and extensive experiments are those summarized by Russell and Kelly [Russell, W. L. & Kelly, E. M: Proc. Natl Acad. Sci. USA 79 (1982) 539-541], which are known as 'Mega-mouse project'. This provides us with important information of the frequencies of transmitted specific-locus mutations induced in mouse spermatogonia stem-cells. It is found that the numerical results of the mutation frequency of mice are in reasonable agreement with the experimental data: the LD model reproduces the total dose and dose rate dependence of data reasonably. In order to see such dose-rate dependence more explicitly, we introduce the dose-rate effectiveness factor (DREF). This represents a sort of preventable effects such as repair, apoptosis and death of broken cells, which are to be competitive with proliferation effect of broken cells induced by irradiation.Comment: subimitting to J. Phys. Soc. Jpn, 32 pages, 8 figure

A range expanding signal conditioner

Telemetry system modifications to improve signal resolution are described. Process uses zero suppression technique which consists of subtracting known voltage from input and amplifying remainder. Schematic diagram of circuit is provided and details of operation are presented

ExpandED Schools National Demonstration: Lessons for Scale and Sustainability

Can schools and community organizations come together to provide children with critical enrichment activities that enhance knowledge and expand horizons beyond core academics during the school day? This report by Policy Studies Associates, Inc., highlights some ways in which they might.The report investigates schools' use of the ExpandED Schools model, which seeks to use partnerships between public schools, community organizations and intermediary organizations to increase enrichment opportunities for children. In the model, regular school staffers focus largely on core academics, while a community-based organization offers enrichment activities during expanded school hours. A third, intermediary organization often coordinates and supports the effort.Researchers studied the use of this model in 10 schools in three cities—New York City, Baltimore and New Orleans—over four years. In this report, they identify the parts of the model that were easiest for the schools to implement, parts that proved more challenging and strategies schools used to overcome hurdles along the way.It finds that the partnerships were generally most successful in adding new activities to an expanded school day and were able to coordinate efforts between school staff and community organizations. But many schools struggled to find reliable sources of funding and to use data to drive programming and instruction

mSpace Mobile: Exploring Support for Mobile Tasks

In the following paper we compare two Web application interfaces, mSpace Mobile and Google Local in supporting location discovery tasks on mobile devices while stationary and while on the move. While mSpace Mobile performed well in both stationary and mobile conditions, performance in Google Local dropped significantly. We postulate that mSpace Mobile performed so well because it breaks the paradigm of the page for delivering Web content, thereby enabling new and more powerful interfaces to be used to support mobility

Three-dimensional modeling of lightning-induced electromagnetic pulses on Venus, Jupiter and Saturn

While lightning activity in Venus is still controversial, its existence in Jupiter and Saturn was first detected by the Voyager missions and later on confirmed by Cassini and New Horizons optical recordings in the case of Jupiter, and recently by Cassini on Saturn in 2009. Based on a recently developed 3D model we investigate the influence of lightning-emitted electromagnetic pulses (EMP) on the upper atmosphere of Venus, Saturn and Jupiter. We explore how different lightning properties such as total energy released and orientation (vertical, horizontal, oblique) can produce mesospheric transient optical emissions of different shapes, sizes and intensities. Moreover, we show that the relatively strong background magnetic field of Saturn can enhance the lightning-induced quasi-electrostatic and inductive electric field components above 1000 km of altitude producing stronger transient optical emissions that could be detected from orbital probes

mSpace Mobile: a UI Gestalt to Support On-the-Go Info-Interaction

mSpace Mobile Interaction presents a UI gestalt of 7 techniques for mobile/on-the-move information retrieval and assessment that enables multiple views of the information within a persistent focus+context viewer. It uses the web but breaks the web page paradigm to support effective rapid triage

The Periodontal Index

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141679/1/jper0585.pd

An inlet analysis for the NASA hypersonic research engine aerothermodynamic integration model

A theoretical analysis for the inlet of the NASA Hypersonic Research Engine (HRE) Aerothermodynamic Integration Model (AIM) has been undertaken by use of a method-of-characteristics computer program. The purpose of the analysis was to obtain pretest information on the full-scale HRE inlet in support of the experimental AIM program (completed May 1974). Mass-flow-ratio and additive-drag-coefficient schedules were obtained that well defined the range effected in the AIM tests. Mass-weighted average inlet total-pressure recovery, kinetic energy efficiency, and throat Mach numbers were obtained

Symptomatic adrenal insufficiency during inhaled corticosteroid treatment

Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment. This case series illustrates the occurence of clinically significant adrenal insufficiency in asthmatic children while patients were on inhaled corticosteroid treatment and the unexpected modes of presentation. General practitioners and paediatricians need to be aware that this unusual but acute serious complication may occur in patients treated

Recovering a lost baseline: missing kelp forests from a metropolitan coast

© 2008 AuthorThere is concern about historical and continuing loss of canopy-forming algae across the world’s temperate coastline. In South Australia, the sparse cover of canopy-forming algae on the Adelaide metropolitan coast has been of public concern with continuous years of anecdotal evidence culminating in 2 competing views. One view considers that current patterns existed before the onset of urbanisation, whereas the alternate view is that they developed after urbanisation. We tested hypotheses to distinguish between these 2 models, each centred on the reconstruction of historical covers of canopies on the metropolitan coast. Historically, the metropolitan sites were indistinguishable from contemporary populations of reference sites across 70 km (i.e. Gulf St. Vincent), and could also represent a random subset of exposed coastal sites across 2100 km of the greater biogeographic province. Thus there was nothing ‘special’ about the metropolitan sites historically, but today they stand out because they have sparser covers of canopies compared to equivalent locations and times in the gulf and the greater province. This is evidence of wholesale loss of canopy-forming algae (up to 70%) on parts of the Adelaide metropolitan coast since major urbanisation. These findings not only set a research agenda based on the magnitude of loss, but they also bring into question the logic that smaller metropolitan populations of humans create impacts that are trivial relative to that of larger metropolitan centres. Instead, we highlight a need to recognise the ecological context that makes some coastal systems more vulnerable or resistant to increasing human-domination of the world’s coastlines. We discuss challenges to this kind of research that receive little ecological discussion, particularly better leadership and administration, recognising that the systems we study out-live the life spans of individual research groups and operate on spatial scales that exceed the capacity of single research providers.Sean D. Connell, Bayden D. Russell, David J. Turner, Scoresby A. Shepherd, Timothy Kildea, David Miller, Laura Airoldi, Anthony Cheshir