Nuclear Cryogenic Propulsion Stage Conceptual Design and Mission Analysis

The Nuclear Cryogenic Propulsion Stage (NCPS) is an in-space transportation vehicle, comprised of three main elements, designed to support a long-stay human Mars mission architecture beginning in 2035. The stage conceptual design and the mission analysis discussed here support the current nuclear thermal propulsion going on within partnership activity of NASA and the Department of Energy (DOE). The transportation system consists of three elements: 1) the Core Stage, 2) the In-line Tank, and 3) the Drop Tank. The driving mission case is the piloted flight to Mars in 2037 and will be the main point design shown and discussed. The corresponding Space Launch System (SLS) launch vehicle (LV) is also presented due to it being a very critical aspect of the NCPS Human Mars Mission architecture due to the strong relationship between LV lift capability and LV volume capacity

DEPLOYTECH: Deployment Technology Survey Web Publication Version

The information in this survey provides a sample of details on deployable structures that have been proposed, tested, and flown from the 1960s to today

Reduction of Launch Mass with Solar Sail Propulsion

No abstract availabl

Lessons Learned from the Flight Unit Testing of the Near Earth Asteroid Scout Flight System

The Near Earth Asteroid Scout flight mission is set to launch on the maiden voyage of the Space Launch System as a secondary payload. The spacecraft will be jettisoned in cis-lunar space and embark on an ambitious 2.5 year mission to image an asteroid. The spacecraft is uniquely equipped with an 85m2 solar sail as the main propulsion system. The monolithic sail system is designed to package within a 6U volume for launch and then deploy during flight. The NEA Scout team has presented in the past to the International Symposium on Solar Sailing topics related to the engineering development unit and design efforts to achieve flight hardware build. This paper will focus on the lessons learned from building and testing the NEA Scout flight system. Focus will be on the mechanical, software, and electrical interfaces as well as preparation for subsystem environmental tests, including thermal vacuum. Due to the unique design of the spacecraft, the solar sail subsystem was required to be located in the center of the spacecraft. This requirement lead to design challenges such as designing and accommodating critical cable harnesses to run through the center of the sail subsystem, packaging and deployment design of the sail subsystem, and integrated testing efforts through an avionics test bed to verify and validate a complete system architecture

Smoking and diabetes

Celem tego artykułu jest podsumowanie danych z literatury dotyczących palenia tytoniu i cukrzycy w odniesieniu do czynników ryzyka, skuteczności i efektywności ekonomicznej różnych metod zrywania z nałogiem oraz ich znaczenia klinicznego. Dokonano przeglądu ponad 200 prac, ze szczególnym uwzględnieniem publikacji, które ukazały się w ciągu ostatnich 10 lat. Włączono tu również badania, które obejmowały chorych na cukrzycę, ale wyniki dotyczące tej grupy pacjentów nie zostały opublikowane oddzielnie. Szczególnie interesujące są prace prowadzone wyłącznie wśród chorych na cukrzycę. Wyniki badań zarówno przekrojowych, jak i prospektywnych są zgodne — palenie tytoniu powoduje zwiększenie ryzyka powikłań z grupy makro- i mikroangiopatii oraz jest przyczyną przedwczesnego zgonu. Istnieje wiele cennych prac dotyczących zaprzestania palenia tytoniu, a ich wyniki potwierdzają efektywność ekonomiczną postępowania prowadzonego w gabinetach lekarskich. Szczególnie dotyczy to rozwiązań systemowych, w ramach których problem palenia tytoniu stanowi zagadnienie omawiane podczas rutynowych wizyt u lekarza. Jednocześnie choremu oferowana jest porada i wsparcie już po zaprzestaniu palenia. Chociaż informacji dotyczących skuteczności postępowania, które ma skłonić chorego na cukrzycę do zaprzestania palenia, jest niewiele, nie ma powodów, aby sądzić, że postępowanie takie będzie mniej lub bardziej skuteczne w tej grupie pacjentów. Biorąc pod uwagę skalę zjawiska, wpływ na chorobowość i powikłania cukrzycy oraz korzyści płynące z zaprzestania palenia tytoniu, należy z całą pewnością zwiększyć częstość porad na ten temat wśród chorych na cukrzycęThe objective of this review is to summarize the literature on diabetes and smoking related to epidemiological risks, efficacy and cost-effectiveness of different cessation approaches, and implications for clinical practice. Over 200 studies were reviewed, with special emphasis placed on publications within the past 10 years. Intervention studies that included patients with diabetes but did not report results separately by disease are included. Diabetesspecific studies are highlighted. There are consistent results from both cross-sectional and prospective studies showing enhanced risk for micro- and macrovascular disease, as well as premature mortality from the combination of smoking and diabetes. The general cessation literature is extensive, generally well-designed, and encouraging regarding the impact of cost-effective practical office-based interventions. In particular, system-based approaches that make smoking a routine part of office contacts and provide multiple prompts, advice, assistance, and follow-up support are effective. Although there is minimal information on the effectiveness of cessation interventions specifically for people with diabetes, there is no reason to assume that cessation intervention would be more or less effective in this population. There is a clear need to increase the frequency of smoking cessation advice and counseling for patients with diabetes given the strong and consistent data on smoking prevalence; combined risks of smoking and diabetes for morbidity, mortality, and several complications; and the proven efficacy and cost-effectiveness of cessation strategies

The Effect of Atorvastatin on Breast Cancer Biomarkers in High-Risk Women

Statins have the potential to reduce breast cancer incidence and recurrence as shown in both epidemiologic and laboratory studies. The purpose of this study was to evaluate the effect of a lipophilic statin, atorvastatin, on breast cancer biomarkers of risk [mammographic density (MD) and insulin growth factor 1 (IGF-1)] in high-risk premenopausal women

Reduction of Martian Sample Return Mission Launch Mass with Solar Sail Propulsion

Solar sails have the potential to provide mass and cost savings for spacecraft traveling within the inner solar system. Companies like L'Garde have demonstrated sail manufacturability and various in-space deployment methods. The purpose of this study was to evaluate a current Mars sample return architecture and to determine how cost and mass would be reduced by incorporating a solar sail propulsion system. The team validated the design proposed by L'Garde, and scaled the design based on a trajectory analysis. Using the solar sail design reduced the required mass, eliminating one of the three launches required in the original architecture

Reduction of Martian Sample Return Mission Launch Mass with Solar Sail Propulsion

Solar sails have the potential to provide mass and cost savings for spacecraft traveling within the innter solar system. Companies like L'Garde have demonstrated sail manufacturability and various i-space development methods. The purpose of this study was to evaluate a current Mars sample return architecture and to determine how cost and mass would be reduced by incorporating a solar sail propulsion system. The team validated the design proposed by L'Garde, and scaled the design based on a trajectory analysis. Using the solar sail design reduced the required mass, eliminating one of the three launches required in the original architecture

Databases for Congenital Heart Defect Public Health Studies Across the Lifespan

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/139106/1/jah31841_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/139106/2/jah31841.pd