642 research outputs found

    So Far from God: The U.S. War with Mexico 1846-1848

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    Agriculture causes nitrate fertilization of remote alpine lakes

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    Humans have altered Earth’s nitrogen cycle so dramatically that reactive nitrogen (Nr) has doubled. This has increased Nr in aquatic ecosystems, which can lead to reduced water quality and ecosystem health. Apportioning sources of Nr to specific ecosystems, however, continues to be challenging, despite this knowledge being critical for mitigation and protection of water resources. Here we use D17O, d18O and d15N from Uinta Mountain (Utah, USA) snow, inflow and lake nitrate in combination with a Bayesian-based stable isotope mixing model, to show that at least 70% of nitrates in aquatic systems are anthropogenic and arrive via the atmosphere. Moreover, agricultural activities, specifically nitrate- and ammonium-based fertilizer use, are contributing most (B60%) Nr, and data from other North American alpine lakes suggest this is a widespread phenomenon. Our findings offer a pathway towards more effective mitigation, but point to challenges in balancing food production with protection of important water resources

    Accelerating influence:Challenging the linear paradigm of suicide negotiation

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    This article provides new insights from crisis negotiation practitioners and researchers. Specifically, on whether a negotiator can accelerate their influence over a suicidal person in crisis

    Green-light generation of picosecond pulses in first-order quasi-phase-matched lithium niobate

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    Bulk periodically poled lithium niobate has been used for efficient first-order quasi-phase matched second harmonic generation of green light in the picosecond regime. We measured an effective nonlinear coefficient of ~14 pm/V

    Atlantic salmon return rate increases with smolt length

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    Recent declines in Atlantic salmon Salmo salar populations are generally attributed to factors in their marine life-phase. However, it is postulated that factors affecting their freshwater life-phase might impact their marine survival, such as the influence of body size. While larger smolts are widely hypothesized to have higher marine survival rates, empirical support remains scant, in part due to inadequate data and ambiguous statistical analyses. Here, we test the influence of smolt body size on marine return rates, a proxy for marine survival, using a 12-year dataset of 3688 smolts tagged with passive integrated transponders in the River Frome, Southern England. State-space models describe the probability of smolts surviving their marine phase to return as 1 sea-winter (1SW) or multi-sea-winter adults as a function of their length, while accounting for imperfect detection and missing data. Models predicted that larger smolts had higher return rates; the most parsimonious model included the effect of length on 1SW return rate. This prediction is concerning, as freshwater juvenile salmon are decreasing in size on the River Frome, and elsewhere. Thus, to maximize adult returns, restoration efforts should focus on freshwater life-stages, and maximize both the number and the size of emigrating smolts

    An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes

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    Parasitic nematodes infect hundreds of millions of people and farmed livestock. Further, plant parasitic nematodes result in major crop damage. The pipeline of therapeutic compounds is limited and parasite resistance to the existing anthelmintic compounds is a global threat. We have developed an INVertebrate Automated Phenotyping Platform (INVAPP) for high-throughput, plate-based chemical screening, and an algorithm (Paragon) which allows screening for compounds that have an effect on motility and development of parasitic worms. We have validated its utility by determining the efficacy of a panel of known anthelmintics against model and parasitic nematodes: Caenorhabditis elegans, Haemonchus contortus, Teladorsagia circumcincta, and Trichuris muris. We then applied the system to screen the Pathogen Box chemical library in a blinded fashion and identified compounds already known to have anthelmintic or anti-parasitic activity, including tolfenpyrad, auranofin, and mebendazole; and 14 compounds previously undescribed as anthelmintics, including benzoxaborole and isoxazole chemotypes. This system offers an effective, high-throughput system for the discovery of novel anthelmintics

    Experimental and computational studies of sonochemical assisted anchoring of carbon quantum dots on reduced graphene oxide sheets towards the photocatalytic activity

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    Herein, carbon quantum dots (CQDs) are anchored on reduced graphene oxide (rGO) sheets by sonochemical assisted method. The developed carbon quantum dots/reduced graphene oxide (CQDs/rGO) catalyst shows enhancement in the photocatalytic degradation of methylene blue and methyl orange under visible light compared to that of individual CQDs and rGO components. The improved performance of the CQDs/rGO catalyst has been attributed to efficient separation of photogenerated charge carriers as studied by photoluminescence studies and to increase in the surface area as studied by Brunauer-Emmett-Teller method. The photocatalytic degradation is studied in detail by varying catalyst loading, dye concentration and the rate constant is determined by first order kinetics. The enhancement in photocatalytic activity of CQDs/rGO catalyst is validated by first principles density functional theory (DFT) calculations which shows the enrichment in density of states thereby decreasing the work function

    Dark Matter Direct Detection Signals inferred from a Cosmological N-body Simulation with Baryons

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    We extract at redshift z=0 a Milky Way sized object including gas, stars and dark matter (DM) from a recent, high-resolution cosmological N-body simulation with baryons. Its resolution is sufficient to witness the formation of a rotating disk and bulge at the center of the halo potential. The phase-space structure of the central galactic halo reveals the presence of a dark disk component, that is co-rotating with the stellar disk. At the Earth's location, it contributes to around 25% of the total DM local density, whose value is rho_DM ~ 0.37 GeV/cm^3. The velocity distributions also show strong deviations from pure Gaussian and Maxwellian distributions, with a sharper drop of the high velocity tail. We give a detailed study of the impact of these features on the predictions for DM signals in direct detection experiments. In particular, the question of whether the modulation signal observed by DAMA is or is not excluded by limits set by other experiments (CDMS, XENON and CRESST...) is re-analyzed and compared to the case of a standard Maxwellian halo, in both the elastic and the inelastic scattering scenarios. We find that the compatibility between DAMA and the other experiments is improved. In the elastic scenario, the DAMA modulation signal is slightly enhanced in the so-called channeling region, as a result of several effects. For the inelastic scenario, the improvement of the fit is mainly attributable to the departure from a Maxwellian distribution at high velocity.Comment: 39 page
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