Against the Tide: Indigenous Knowledge and Education for Humanization

Power brokers and their market economies enforce education on a global level. According to the United Nations, the effects of global neoliberal capitalism cause human rights violations in all parts of the world, yet democratic countries scoff at these findings (Pogge, 2002 & 2005). People of the world continue to believe that tying minoritized students to existing structures and ensuring enculturation is the best possible outcome for all involved (Suárez-Orozco & Suárez-Orozco, 2015). That is, minoritized children are educated to ensure first-world countries produce a minimally educated and willing labor force. In this paper we argue the following: 1) power relations among global economies lead to displacement and migration (nothing new), and 2) an alternative lens for ameliorating these conditions: Indigenous knowledge as a counterpoint to power relations; toward recreating an egalitarian and socially just society

The Formation of Brown Dwarfs: Observations

We review the current state of observational work on the formation of brown dwarfs, focusing on their initial mass function, velocity and spatial distributions at birth, multiplicity, accretion, and circumstellar disks. The available measurements of these various properties are consistent with a common formation mechanism for brown dwarfs and stars. In particular, the existence of widely separated binary brown dwarfs and a probable isolated proto-brown dwarf indicate that some substellar objects are able to form in the same manner as stars through unperturbed cloud fragmentation. Additional mechanisms such as ejection and photoevaporation may play a role in the birth of some brown dwarfs, but there is no observational evidence to date to suggest that they are the key elements that make it possible for substellar bodies to form.Comment: Protostars and Planets V, in pres

Construction of the new Harrison County Highway Department Facility

The session covers everything that went into this award-winning project, from the political collaboration, through the design process, to the successful construction, occupation, and use of the new facility. We’ve had a lot of interest from other counties visiting our new site

Beyond the Invisible Barriers of the Classroom: iEngage and Civic Praxis

Research literature suggests students need to engage in actual civic experiences; however, in most cases, teachers feel unwilling or unable to facilitate experiences beyond the formal classroom setting. In this project, we sought to understand the relationship between social studies teachers’ civic ideology, pedagogical approaches, and instructional decision-making through their engagement in an action civics camp. The project is part of a more significant effort to help critically minded teachers engage in more activist praxis by moving past the often-limiting ideological barriers of the classroom. By activist praxis, we refer to the ways a teacher’s ideology informs pedagogy related to the ways they are able and willing to extend civic engagement into the material and social world. Activist praxis is part of a teacher’s continual engagement in efforts to create the conditions for a more just and equitable public sphere

Progress in cavity QED with single trapped atoms

We report on recent progress in our lab involving cavity quantum electrodynamics with optically trapped atoms. In particular, we will focus on a recent measurement of the Vacuum-Rabi splitting for one atom strongly coupled to the field of a high finesse optical resonator. This splitting is characteristic of the normal modes in the eigenvalue spectrum of the atom-cavity system. A new Raman scheme for cooling atomic motion along the cavity axis enables a complete spectrum to be recorded for an individual atom trapped within the cavity mode, in contrast to all previous measurements in cavity QED that have required averaging over many atoms

Sampling nucleotide diversity in cotton

<p>Abstract</p> <p>Background</p> <p>Cultivated cotton is an annual fiber crop derived mainly from two perennial species, <it>Gossypium hirsutum </it>L. or upland cotton, and <it>G. barbadense </it>L., extra long-staple fiber Pima or Egyptian cotton. These two cultivated species are among five allotetraploid species presumably derived monophyletically between <it>G. arboreum </it>and <it>G. raimondii</it>. Genomic-based approaches have been hindered by the limited variation within species. Yet, population-based methods are being used for genome-wide introgression of novel alleles from <it>G. mustelinum </it>and <it>G. tomentosum </it>into <it>G. hirsutum </it>using combinations of backcrossing, selfing, and inter-mating. Recombinant inbred line populations between genetics standards TM-1, (<it>G. hirsutum</it>) × 3-79 (<it>G. barbadense</it>) have been developed to allow high-density genetic mapping of traits.</p> <p>Results</p> <p>This paper describes a strategy to efficiently characterize genomic variation (SNPs and indels) within and among cotton species. Over 1000 SNPs from 270 loci and 279 indels from 92 loci segregating in <it>G. hirsutum </it>and <it>G. barbadense </it>were genotyped across a standard panel of 24 lines, 16 of which are elite cotton breeding lines and 8 mapping parents of populations from six cotton species. Over 200 loci were genetically mapped in a core mapping population derived from TM-1 and 3-79 and in <it>G. hirsutum </it>breeding germplasm.</p> <p>Conclusion</p> <p>In this research, SNP and indel diversity is characterized for 270 single-copy polymorphic loci in cotton. A strategy for SNP discovery is defined to pre-screen loci for copy number and polymorphism. Our data indicate that the A and D genomes in both diploid and tetraploid cotton remain distinct from each such that paralogs can be distinguished. This research provides mapped DNA markers for intra-specific crosses and introgression of exotic germplasm in cotton.</p

Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy

Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default LicenseIn HIV infection, persistent inflammation despite effective antiretroviral therapy is linked to increased risk of noninfectious chronic complications such as cardiovascular and thromboembolic disease. A better understanding of inflammatory and coagulation pathways in HIV infection is needed to optimize clinical care. Markers of monocyte activation and coagulation independently predict morbidity and mortality associated with non-AIDS events. We identified a specific subset of monocytes that express tissue factor (TF), persist after virological suppression, and trigger the coagulation cascade by activating factor X. This subset of monocytes expressing TF had a distinct gene signature with up-regulated innate immune markers and evidence of robust production of multiple proinflammatory cytokines, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and IL-6, ex vivo and in vitro upon lipopolysaccharide stimulation. We validated our findings in a nonhuman primate model, showing that TF-expressing inflammatory monocytes were associated with simian immunodeficiency virus (SIV)-related coagulopathy in the progressive [pigtail macaques (PTMs)] but not in the nonpathogenic (African green monkeys) SIV infection model. Last, Ixolaris, an anticoagulant that inhibits the TF pathway, was tested and potently blocked functional TF activity in vitro in HIV and SIV infection without affecting monocyte responses to Toll-like receptor stimulation. Strikingly, in vivo treatment of SIV-infected PTMs with Ixolaris was associated with significant decreases in D-dimer and immune activation. These data suggest that TF-expressing monocytes are at the epicenter of inflammation and coagulation in chronic HIV and SIV infection and may represent a potential therapeutic target.This study was supported by the NIH Intramural Research Program, National Institute of Allergy and Infectious Diseases, and Bench-to-Bedside award R01HL117715-10S1 (to I.S. and I.P.). Part of this project has been also funded with federal funds from the National Cancer Institute, NIH, under contract no. HHSN261200800001E. The NHP study has also been funded in part with federal funds from the NIH (R01 HL123096 and RO1 HL117715 to I.P., R01 AI119346 to C.A., and R01AI104373 to R.M.R.).info:eu-repo/semantics/publishedVersio