277 research outputs found
A SEMIOTIC ANALYSIS OF NOVEL ILLUSTRATION THE HOUND OF ROWAN TAPESTRY BY HENRY H. NEFF (2007)
ABSTRACT
The purpose of this research is to determine and describe the meaning of symbol and
illustration in the novel The Hound of Rowan: The Tapestry. This research is a
qualitative research and the data source is from the novel itself entitled The Hound of
Rowan: The Tapestry by Henry H. Neff (2007). This research attempts to discuss the
problems as 1) types of symbols and illustration used in the novel, and 2) the meaning
of symbols and illustration used in the novel The Hound of Rowan: The Tapestry.
This research is using a written document to collect the data and it is used a semiotic
analysis by Ferdinan d’Saussure (1959) and Charles Sander Pierce (1839-1914) in
analyzing the topics. Based on the analysis result, the researcher found the symbols
and illustrations and it's meaning depicted in the novel, namely: symbol of anger, true
love, jealousy, then the illustration is depicted of sadness illustration
Pre-operative Radiotherapy And Deep Inferior Epigastric Artery Perforator (DIEP) flAp study (PRADA): Aesthetic outcome and patient satisfaction at one year.
INTRODUCTION: The optimal combination of radiotherapy and breast reconstruction has not yet been defined. Post-mastectomy radiotherapy (PMRT) has deleterious effects on breast reconstruction, leading to caution amongst surgeons. Pre-operative radiotherapy (PRT) is a growing area of interest, is demonstrated to be safe, and spares autologous flaps from radiotherapy. This study evaluates the aesthetic outcome of PRT and deep inferior epigastric artery perforator (DIEP) flap reconstruction within the Pre-operative Radiotherapy And Deep Inferior Epigastric artery Perforator (DIEP) flAp (PRADA) cohort. METHODS: PRADA was an observational cohort study designed to evaluate the feasibility and safety of PRT for women undergoing neoadjuvant chemotherapy and DIEP reconstruction. Panel evaluation of 3D surface images (3D-SIs) and patient-reported outcome measures (BREAST-Q) for a subset of women in the study were compared with those of a DIEP-PMRT cohort who had undergone DIEP reconstruction and PMRT. RESULTS: Seventeen out of 33 women from the PRADA study participated in this planned substudy. Twenty-eight women formed the DIEP-PMRT cohort (median follow-up 23 months). The median (inter-quartile range [IQR]) 'satisfaction with breasts' score at 12 months for the PRADA cohort was significantly better than the DIEP-PMRT cohort (77 [72-87] versus 64 [54-71], respectively), p=0.01). Median [IQR] panel evaluation (5-point scale) was also significantly better for the PRADA cohort than for the DIEP-PMRT cohort (4.3 [3.9-4.6] versus 3.6 [2.8-4] p=0.003). CONCLUSIONS: Aesthetic outcome for the PRADA cohort was reported to be 'good' or 'excellent' in 93% of cases using a bespoke panel assessment with robust methodology. Patient satisfaction at one year is encouraging and superior to DIEP-PMRT at 23 months. Switching surgery-radiotherapy sequencing leads to similar breast aesthetic outcomes and warrants further large-scale, multi-centre evaluation in a randomised trial
The use of ultrasound in the clinical re-staging of the axilla after neoadjuvant chemotherapy (NACT).
Introduction Ultrasound (US) is the imaging modality of choice for staging the axilla prior to surgery in patients with breast cancer (BC). High pathological complete response rates in the axilla after NACT mean a more conservative approach to surgery can be considered. Radiological re-staging is important in this decision making. After the presentation of results from ACOSOG Z1071 in December 2012, formal ultrasound re-assessment of the axilla after primary therapy was specifically requested in our institution. We report on the accuracy of axillary US (aUS) for identifying residual axillary disease post-NACT.Methods Data were collected on patients who had proven axillary disease prior to NACT and underwent axillary lymph node dissection after NACT between January 2013 and December 2015. Post-chemotherapy aUS reports and axillary pathology reports were classified as positive or negative for abnormal lymph nodes and for residual disease (cCR and pCR respectively).Results The sensitivity and specificity of aUS was 71% and 88% respectively. The negative predictive value (NPV) was 83%. The false negative rate was 29%.Conclusions Axillary ultrasound provides clinically useful information post-NACT, which will guide surgical decision-making. Patients with aUS-negative axillae are likely to have a lower false negative rate of SLNB after NACT (Boughey et al.). However, aUS does not replace the need to identify and biopsy the nodes which were proven to be positive prior to NACT
Measurement of the angle, temperature and flux of fast electrons emitted from intense laser-solid interactions
High-intensity laser-solid interactions generate relativistic electrons, as well as high-energy (multi-MeV) ions and X-rays. The directionality, spectra and total number of electrons that escape atarget-foil is dependent on the absorption, transport and rear-side sheath conditions. Measuring the electrons escaping the target will aid in improving our understanding of these absorption processes and the rear-surface sheath fields that retard the escaping electrons and accelerate ions via the target normal sheath acceleration (TNSA) mechanism. A comprehensive Geant4 study was performed to help analyse measurements made with a wrap-around diagnostic that surrounds the target and uses differential filtering with a FUJI-film image plate detector. The contribution of secondary sources such as X-rays and protons to the measured signal have been taken into account to aid in the retrieval of the electron signal. Angular and spectral data from a high-intensity laser-solid interaction are presented and accompanied by simulations. The total number of emitted electrons has been measured as 2.6 × 1013 with an estimated total energy of 12 ± 1 J from a 100 mu;m Cu target with140 J of incident laser energy during a 4 × 1020 W cm-2 interaction
High efficiency proton beam generation through target thickness control in femtosecond laser-plasma interactions
Bright proton beams with maximum energies of up to 30MeV have been observed in an experiment investigating ion sheath acceleration driven by a short pulse (21 W cm-2 was investigated, with the interplay between target thickness and laser pre-pulse found to be a key factor. While the maximum proton energies observed were maximised for lm-thick targets, the total proton energy content was seen to peak for thinner, 500 nm, foils. The total proton beam energy reached up to 440 mJ (a conversion efficiency of 4%), marking a significant step forward for many laser-driven ion applications. The experimental results are supported by hydrodynamic and particle-in-cell simulations
The natural capital approach to integrating science, economics and policy into decisions affecting the natural environment
This is the final version. Available on open access from Cambridge University Press via the DOI in this recordNatural capital refers to those stocks of assets provided for free by nature which, directly or indirectly, deliver well-being for humans. These include freshwater, fertile soils, clean air and living things. Natural capital stocks deliver flows of services, often called ecosystem services, which (often in combination with flows from other capital including human labour, ingenuity and manufactured goods) produce the benefits upon which humans depend for economic well-being and their very existence. Economic activity depends on natural capital while also affecting the stock of those assets. This relationship between the environment, the economy and human well-being has caught the attention of governments at both global and national levels. But how should governments incorporate the notion of natural capital into policy- and decision-making? We set out to define the notion of natural capital and how it can be brought into the economic analyses which underpin the majority of policy decision-making systems. We consider the means by which changes can be best directed to reflect the underlying science of the environment, the incentives of the economy and the preferences of society.Natural Environment Research Council (NERC
Role of lattice structure and low temperature resistivity on fast electron beam filamentation in carbon
The influence of low temperature (eV to tens-of-eV) electrical resistivity on the onset of the filamentation instability in fast-electron transport is investigated in targets comprising of layers of ordered (diamond) and disordered (vitreous) carbon. It is shown experimentally and numerically that the thickness of the disordered carbon layer influences the degree of filamentation of the fast-electron beam. Strong filamentation is produced if the thickness is of the order of 60 μm or greater, for an electron distribution driven by a sub-picosecond, mid-1020 Wcm-2 laser pulse. It is shown that the position of the vitreous carbon layer relative to the fast-electron source (where the beam current density and background temperature are highest) does not have a strong effect because the resistive filamentation growth rate is high in disordered carbon over a wide range of temperatures up to the Spitzer regime
Detector for imaging and dosimetry of laser-driven epithermal neutrons by alpha conversion
An epithermal neutron imager based on detecting alpha particles created by boron neutron capture mechanism is discussed. The diagnostic mainly consists of a mm thick Boron Nitride (BN) sheet (as an alpha converter) in contact with a non-borated cellulose nitride film (LR115 type-II) detector. While the BN absorbs the neutrons below 0.1 eV, the fast neutrons register insignificantly in the detector due to their low neutron capture and recoil cross-sections. The use of solid-state nuclear track detectors (SSNTD), unlike image plates, micro-channel plates and scintillators, provide safeguard from the x-rays, gamma-rays and electrons. The diagnostic was tested on a proof-of-principle basis, in front of a laser driven source of moderated neutrons, which suggests the potential of using this diagnostic (BN+SSNTD) for dosimetry and imaging applications
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