THE PSYCHOLOGICAL EFFECTS OF COVID 19 ON MEDICAL AND NON-MEDICAL UNIVERSITY STUDENTS

Background: The COVID 19 pandemic has had significant psychological effects on university students as well as in all segments of society. The aim of this study is to examine the relationship between education fields (medical-non medical), education styles (online-face to face), sociodemographic characteristics of university students and their levels of depression, anxiety, stress, fear of COVID-19. Subjects and methods: In the cross-sectional designed research, 1213 university students studying in Turkey was reached online. A sociodemographic form, the Depression Anxiety Stress Scale (DASS 21) and the Fear of COVID-19 Scale (FCV-19S) was applied to the participants. Results: Of all participants 887(73%) were women. 647(53%) students were studying in the medical field. The scores of FCV- 19S and all subscales of DASS 21 were significantly higher in women. In the comparison between the field and style of education, no difference was found. DASS 21 scores were higher in the participants whose relatives had COVID-19 or who had a mental disorder in the past or medical disease. Conclusions: In this study, it was observed that while there was no significant difference in the scores of DASS 21 among university students in terms of the field and style of education, variables such as gender, not having COVID-19 so far, having lost a relative due to COVID-19 could cause significant differences. Identifying sensitive groups will create early intervention opportunities

THE PSYCHOLOGICAL EFFECTS OF COVID 19 ON MEDICAL AND NON-MEDICAL UNIVERSITY STUDENTS

Background: The COVID 19 pandemic has had significant psychological effects on university students as well as in all segments of society. The aim of this study is to examine the relationship between education fields (medical-non medical), education styles (online-face to face), sociodemographic characteristics of university students and their levels of depression, anxiety, stress, fear of COVID-19. Subjects and methods: In the cross-sectional designed research, 1213 university students studying in Turkey was reached online. A sociodemographic form, the Depression Anxiety Stress Scale (DASS 21) and the Fear of COVID-19 Scale (FCV-19S) was applied to the participants. Results: Of all participants 887(73%) were women. 647(53%) students were studying in the medical field. The scores of FCV- 19S and all subscales of DASS 21 were significantly higher in women. In the comparison between the field and style of education, no difference was found. DASS 21 scores were higher in the participants whose relatives had COVID-19 or who had a mental disorder in the past or medical disease. Conclusions: In this study, it was observed that while there was no significant difference in the scores of DASS 21 among university students in terms of the field and style of education, variables such as gender, not having COVID-19 so far, having lost a relative due to COVID-19 could cause significant differences. Identifying sensitive groups will create early intervention opportunities

Magnetic resonance imaging based kidney volume assessment for risk stratification in pediatric autosomal dominant polycystic kidney disease

IntroductionIn the pediatric context, most children with autosomal dominant polycystic kidney disease (ADPKD) maintain a normal glomerular filtration rate (GFR) despite underlying structural kidney damage, highlighting the critical need for early intervention and predictive markers. Due to the inverse relationship between kidney volume and kidney function, risk assessments have been presented on the basis of kidney volume. The aim of this study was to use magnetic resonance imaging (MRI)-based kidney volume assessment for risk stratification in pediatric ADPKD and to investigate clinical and genetic differences among risk groups.MethodsThis multicenter, cross-sectional, and case-control study included 75 genetically confirmed pediatric ADPKD patients (5–18 years) and 27 controls. Kidney function was assessed by eGFR calculated from serum creatinine and cystatin C using the CKiD-U25 equation. Blood pressure was assessed by both office and 24-hour ambulatory measurements. Kidney volume was calculated from MRI using the stereological method. Total kidney volume was adjusted for the height (htTKV). Patients were stratified from A to E classes according to the Leuven Imaging Classification (LIC) using MRI-derived htTKV.ResultsMedian (Q1-Q3) age of the patients was 6.0 (2.0–10.0) years, 56% were male. There were no differences in sex, age, height-SDS, or GFR between the patient and control groups. Of the patients, 89% had PKD1 and 11% had PKD2 mutations. Non-missense mutations were 73% in PKD1 and 75% in PKD2. Twenty patients (27%) had hypertension based on ABPM. Median htTKV of the patients was significantly higher than controls (141 vs. 117 ml/m, p = 0.0003). LIC stratification revealed Classes A (38.7%), B (28%), C (24%), and D + E (9.3%). All children in class D + E and 94% in class C had PKD1 variants. Class D + E patients had significantly higher blood pressure values and hypertension compared to other classes (p > 0.05 for all).DiscussionThis study distinguishes itself by using MRI-based measurements of kidney volume to stratify pediatric ADPKD patients into specific risk groups. It is important to note that PKD1 mutation and elevated blood pressure were higher in the high-risk groups stratified by age and kidney volume. Our results need to be confirmed in further studies

Examining the web sites of women's non-govermental organizations: The example of Havle Women's Association

Bu tez çalışması, kadın haklarını savunan sivil toplum kuruluşlarının, web siteleri ve sosyal medya aracılığı ile kendilerini ifade etme ve alan içinde konumlama yöntemlerine odaklanmakta, örneklem olarak seçilen Havle Kadın Derneği'nin çalışmalarına ayrıntılı olarak yer vermektedir. Öncelikle kadın hareketi tarihsel süreç içerisinde tanımlanmış, Havle Kadın Derneği'nin misyonu gereği İslami Feminizm akımına özel bir önem verilmiş, ardından kamuoyu oluşturmada güncel bir aktivite alanı olan sosyal mecraların özellikleri açıklanmıştır. Tezin son bölümünde Havle Kadın Derneği'ne ait web sitesi incelenmekte ve derneğin Müslüman Feminist kimliğini web sitesi üzerinden sunuş biçimi açıklanmaktadır. Derneğin sosyal medya kullanımına ait örnekler de analizi destekleyecek şekilde çalışmaya dahil edilmiştir. Çalışmada kullanılan yöntem söylem analizi ve göstergebilimdir.This thesis is centred on the techniques of non-governmental organizations advocating for the women's rights to convey themselves through their websites and social media and to position themselves in the field, and thoroughly examines the works of Havle Women's Association, which was chosen as a sample. First of all, the women's movement was determined in the historical process, the Islamic Feminism movement was given importance in accordance with the mission of Havle Women's Association, then the explanation of the characteristics of social media, which is a current field of activity in forming public opinion were made. In the last part of the thesis, the website of Havle Women's Association is inspected and the way the association presents its Muslim Feminist identity on the website is explained. Examples of the association's use of social media were also included in the study to support the analysis. The method used in the study is discourse analysis and semiotics

Clinical and subclinical acute kidney injury in children with mild-to-moderate COVID-19

Background Our aim was to identify acute kidney injury (AKI) and subacute kidney injury using both KDIGO criteria and urinary biomarkers in children with mild/moderate COVID-19. Methods This cross-sectional study included 71 children who were hospitalized with a diagnosis of COVID-19 from 3 centers in Istanbul and 75 healthy children. We used a combination of functional (serum creatinine) and damage (NGAL, KIM-1, and IL-18) markers for the definition of AKI and subclinical AKI. Clinical and laboratory features were evaluated as predictors of AKI and subclinical AKI. Results Patients had significantly higher levels of urinary biomarkers and urine albumin-creatinine ratio than healthy controls (p < 0.001). Twelve patients (16.9%) developed AKI based on KDIGO criteria, and 22 patients (31%) had subclinical AKI. AKI group had significantly higher values of neutrophil count on admission than both subclinical AKI and non-AKI groups (p < 0.05 for all). Neutrophil count was independently associated with the presence of AKI (p = 0.014). Conclusions This study reveals that even children with a mild or moderate disease course are at risk for AKI. Association between neutrophil count and AKI may point out the role of inflammation in the development of AKI. Impact The key message of our article is that not only children with severe disease but also children with mild or moderate disease have an increased risk for kidney injury due to COVID-19. Urinary biomarkers enable the diagnosis of a significant number of patients with subclinical AKI in patients without elevation in serum creatinine. Our findings reveal that patients with high neutrophil count may be more prone to develop AKI and should be followed up carefully. We conclude that even children with mild or moderate COVID-19 disease courses should be evaluated for AKI and subclinical AKI, which may improve patient outcomes

Table1_Magnetic resonance imaging based kidney volume assessment for risk stratification in pediatric autosomal dominant polycystic kidney disease.xlsx

IntroductionIn the pediatric context, most children with autosomal dominant polycystic kidney disease (ADPKD) maintain a normal glomerular filtration rate (GFR) despite underlying structural kidney damage, highlighting the critical need for early intervention and predictive markers. Due to the inverse relationship between kidney volume and kidney function, risk assessments have been presented on the basis of kidney volume. The aim of this study was to use magnetic resonance imaging (MRI)-based kidney volume assessment for risk stratification in pediatric ADPKD and to investigate clinical and genetic differences among risk groups.MethodsThis multicenter, cross-sectional, and case-control study included 75 genetically confirmed pediatric ADPKD patients (5–18 years) and 27 controls. Kidney function was assessed by eGFR calculated from serum creatinine and cystatin C using the CKiD-U25 equation. Blood pressure was assessed by both office and 24-hour ambulatory measurements. Kidney volume was calculated from MRI using the stereological method. Total kidney volume was adjusted for the height (htTKV). Patients were stratified from A to E classes according to the Leuven Imaging Classification (LIC) using MRI-derived htTKV.ResultsMedian (Q1-Q3) age of the patients was 6.0 (2.0–10.0) years, 56% were male. There were no differences in sex, age, height-SDS, or GFR between the patient and control groups. Of the patients, 89% had PKD1 and 11% had PKD2 mutations. Non-missense mutations were 73% in PKD1 and 75% in PKD2. Twenty patients (27%) had hypertension based on ABPM. Median htTKV of the patients was significantly higher than controls (141 vs. 117 ml/m, p = 0.0003). LIC stratification revealed Classes A (38.7%), B (28%), C (24%), and D + E (9.3%). All children in class D + E and 94% in class C had PKD1 variants. Class D + E patients had significantly higher blood pressure values and hypertension compared to other classes (p > 0.05 for all).DiscussionThis study distinguishes itself by using MRI-based measurements of kidney volume to stratify pediatric ADPKD patients into specific risk groups. It is important to note that PKD1 mutation and elevated blood pressure were higher in the high-risk groups stratified by age and kidney volume. Our results need to be confirmed in further studies.</p