Propuesta de Supply Chain Management y logística para la empresa Foodbox S.AS.

Cuadro comparativo del LPISe realizará un análisis detallado sobre la compañía Foodbox sas, la cual es una compañía colombiana dedicada a la comercialización de pollo, ubicada en Bogotá D.C, como punto estratégico para la distribución nacional. Basados en la teoría vista del diplomado en Supply Chain Management y Logística, realizamos una serie de propuestas donde se puso en práctica el conocimiento adquirido buscando optimizar y mejorar los procesos de la compañía, donde se rediseño el espacio de almacenamiento para tener un mejor control de inventarios, rotación del producto y reducción de los tiempos por desplazamiento en cada uno de los procesos ya sea en la recepción del producto y en el despacho de este. Redistribución de las zonas de entrega al igual que la tipología de vehículos implementada para la misma, logrando así impactar significativamente en los gastos logísticos causados por el transporte, movilizando mayores volúmenes en vehículos de mayor capacidad reduciendo el número de viajes. Como otro de los puntos relevantes en el acompañamiento a la compañía es el de utilizar más la tecnología para su comercialización y publicidad, implementando las redes sociales para ser de más fácil acceso a los clientes finales.A detailed analysis will be carried out on the Foodbox sas company, which is a Colombian company dedicated to the commercialization of chicken, located in Bogotá D.C, as a strategic point for national distribution. Based on the theory seen in the Diploma in Supply Chain Management and Logistics, we made a series of proposals where the acquired knowledge was put into practice seeking to optimize and improve the company's processes, where the storage space was redesigned to have better control of inventories, product rotation and reduction of travel times in each of the processes, whether in the reception of the product and in its dispatch. Redistribution of delivery areas as well as the type of vehicles implemented for it, thus achieving a significant impact on logistics costs caused by transportation, mobilizing larger volumes in larger capacity vehicles, reducing the number of trips. As another of the relevant points in the accompaniment to the company is to use more technology for marketing and advertising, implementing social networks to be more easily accessible to end customers

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population