Ruptured middle cerebral artery aneurysms. retrospective study and multivariate analysis of 105 patients treated by surgical clipping

Objective of the study: We analyze in this study only patients with surgically treated ruptured aneurysms in order to identify statistical significance of each predictive factor in terms of outcome of patients with ruptured MCAAs. Materials and methods: In this retrospective study, we analyzed 105 cases of ruptured MCAAs, admitted from January 2001 to December 2015 at Neurosurgical Department of Umberto I University Hospital of Rome, Italy. Predictive factors evaluated are: Patient’s features (age, sex, co-morbidities), aneurysmal location (proximal, bifurcation or distal) and size of aneurysmal dome (small, large or giant); surgical timing (ultra-early, early, delayed), and Intracerebral Hemorrhage (ICH) volume. For each parameter we calculated mean and standard deviation, covariance and relation coefficient (through the linear regression model). Results: The clinical evaluation of patients assessed through the World Federation of Neurological Surgeons (WFSN) grading scale, that is 5 for 37 patients (35.3%), 4 for 28 patients. In 40% of cases the maximum sac diameter was between 7 mm and 12 mm, while in 67% of the cases the aneurysms concerned the bifurcation of the middle cerebral artery. ICH was associated in 57 cases (54.3%). As far as outcome is concerned, at 3 months, 32 patients (30.47%) had a favourable outcome, while 73 (69.52%) patients had not favourable outcome. To one year, 46 patients (43.8%) had favourable outcomes, while 59 patients (56.19%) had not favourable outcome. The mean outcomes as mean mRS are significantly less favourable in patients with ICH. Conclusion: In MCAAs patients, the presence of ICH strongly affects the outcome with a marked increase in mortality and morbidity. Surgical timing significantly influences the outcomes and ultra-early surgery should always be taken into account

Intervención federal a la Provincia de Mendoza en el año 1974 : su inconstitucionalidad

Fil: Ruggeri, María Delicia. Universidad Nacional de Cuyo. Facultad de Derecho. Mendoza, ArgentinaFil: Rocamora, Sergio Roberto. Universidad de Buenos Aires. Facultad de Derecho. Buenos Aires, Argentin

An Extremely Rare Case of Thoracic Intramedullary Melanocytoma: Case Report and Review of Literature

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Combination of pharmacotherapy and lidocaine analgesic block of the peripheral trigeminal branches for trigeminal neuralgia: a pilot study

Classical trigeminal neuralgia (CTN) is treated predominantly by pharmacotherapy but side effects and unsuccessful occurs. The current study was carried out to evaluate the therapeutic effect of combination of pharmacotherapy and lidocaine block. Thirteen patients with CTN managed with pharmacotherapy were recruited and assigned either to no additional treatment (Group I) or to additional analgesic block (Group II). The primary endpoint was the reduction in the frequency of pain episodes in a month assessed at 30 and 90 days. Comparisons of measurements of pain, general health and depression scales were secondary endpoints. The results from the follow-up visits at 30 and 90 days showed the Group II to have larger reduction in the frequency of pain and exhibited a bigger improvement in the scores of the pain, general health and depression scales. The results from this preliminary study suggest a clinical benefit of the combination of pharmacotherapy and lidocaine block

West Nile Virus: Characteristics of an African Virus Adapting to the Third Millennium World

The emergence and spread of West Nile Virus (WNV) from North through South America during the last decade, and the recent outbreaks of disease in both humans and horses in Europe suggest that the epidemiology of this infection is evolving. WNV is now considered among the emerging threats for both human and veterinary public health in areas like Europe where it was previously regarded to as an exotic agent. Further knowledge has built up from studies investigating the characteristics of the virus and its genome evolution capacity, the adaptation to new avian host species, the changes in vector competence and biology, and the host-pathogen interactions, including the immune response. Also, the new needs for preparedness to future major outbursts of disease have stimulated research on virus detection and characterization, filling the gaps in both specialized diagnostic technology and the need for field rapid assays. This review will present an overview of WNV virology, remarking the impact of virus diversity and evolution on theoretical and practical aspects involved in both risk definition, detection and control of infection

Treatment of combined dairy and domestic wastewater with constructed wetland system in Sicily (Italy). Pollutant removal efficiency and effect of vegetation

Dairy wastewater (DWW) contains large amounts of mineral and organic compounds, which can accumulate in soil and water causing serious environmental pollution. A constructed wetland (CW) is a sustainable technology for the treatment of DWW in small-medium sized farms. This paper reports a two-year study on the performance of a pilot-scale horizontal subsurface flow system forDWWtreatment in Sicily (Italy). The CW system covered a total surface area of 100 m2 and treated approximately 6 m3 per day of wastewater produced by a small dairy farm, subsequent to biological treatment. Removal efficiency (RE) of the system was calculated. The biomass production of two emergent macrophytes was determined and the effect of plant growth on organic pollutant RE was recorded. All DWW parameters showed significant differences between inlet and outlet. For BOD5 and COD, RE values were 76.00% and 62.00%, respectively. RE for total nitrogen (50.70%) was lower than that of organic compounds. RE levels of microbiological parameters were found to be higher than 80.00%. Giant reed produced greater biomass than umbrella sedge. A seasonal variation in RE of organic pollutants was recorded due to plant growth rate Our findings highlight the efficient use of a CW system for DWW treatment in dairy-cattle farms

A GPS-less on-demand mobile sink-assisted datacollection in wireless sensor networks

International audienceThe autonomous data collector is a role recentlyintroduced to improve the performance of Wireless SensorNetworks. When a prompt response for data processing andoffloading is necessary, i.e. in the case of event-driven networks,a mobile flying sink could be a good option for that role.In this paper, we introduce FreeFall, a distributed algorithmfor the autonomous navigation of a mobile collector through aWSN for on-demand data offloading that does not rely on anabsolute coordinate system. We show that, under fairly commoncircumstances, it is possible to set the trajectory of the mobilesink and fulfill the offloading requests without the needs ofadditional equipment installed on nodes.We show how our systemis preferable over more classical routing solutions especially in thepresence of localized generation of large amounts of information