Odd C-P contributions to diffractive processes

We investigate contributions to diffractive scattering, which are odd under C- and P-parity. Comparison of p-$\bar p$ and p-p scattering indicates that these odderon contributions are very small and we show how a diquark clustering in the proton can explain this effect. A good probe for the odderon exchange is the photo- and electroproduction of pseudo-scalar mesons. We concentrate on the pi^0 and show that the quasi elastic pi^0-production is again strongly suppressed for a diquark structure of the proton whereas the cross sections for diffractive proton dissociation are larger by orders of magnitude and rather independent of the proton structure.Comment: 18 pages, LaTex2e, graphicx package, 14 eps figures include

Diffractive color-dipole nucleon scattering

We determine the diffractive scattering amplitude of a color-dipole on a nucleon using a non-perturbative model of QCD which contains only parameters taken from low-energy physics. This allows to relate specific features of the confinement mechanisms with diffractive electro-production processes and structure functions. The agreement with phenomenological data is satisfactory.Comment: 7 pages, 5 eps-figures, uses eps

Decomposition of the QCD String into Dipoles and Unintegrated Gluon Distributions

We present the perturbative and non-perturbative QCD structure of the dipole-dipole scattering amplitude in momentum space. The perturbative contribution is described by two-gluon exchange and the non-perturbative contribution by the stochastic vacuum model which leads to confinement of the quark and antiquark in the dipole via a string of color fields. This QCD string gives important non-perturbative contributions to high-energy reactions. A new structure different from the perturbative dipole factors is found in the string-string scattering amplitude. The string can be represented as an integral over stringless dipoles with a given dipole number density. This decomposition of the QCD string into dipoles allows us to calculate the unintegrated gluon distribution of hadrons and photons from the dipole-hadron and dipole-photon cross section via kT-factorization.Comment: 43 pages, 14 figure

Log(1/x) Gluon Distribution and Structure Functions in the Loop-Loop Correlation Model

We consider the interaction of the partonic fluctuation of a scalar ``photon'' with an external color field to calculate the leading and next-to-leading order gluon distribution of the proton following the work done by Dosch-Hebecker-Metz-Pirner. We relate these gluon distributions to the short and long distance behavior of the cross section of an adjoint dipole scattering off a proton. The leading order result is a constant while the next-to-leading order result shows a ln(1/x) enhancement at small x. To get numerical results for the gluon distributions at the initial scale Q^2_0=1.8 GeV^2, we compute the adjoint dipole-proton cross section in the loop-loop correlation model. Quark distributions at the same initial scale are parametrized according to Regge theory. We evolve quark and gluon distributions to higher Q^2 values using the DGLAP equation and compute charm and proton structure functions in the small-x region for different Q^2 values.Comment: 13 pages, 10 figures,revised version,references added, typos corrected, to be published in Eur. Phys. Journal

Two Photon Reactions at High Energies

Cross sections for the reactions gamma^(*) gamma^(*) --> hadrons and gamma^(*) gamma^(*) --> 2 vector mesons are calculated as functions of energy (sqrt(s) > 20 GeV) and photon virtualities. Good agreement with experiment is obtained for the total hadronic cross section and, after allowing for a valence-quark contribution from the hadronic part of the photon, with the photon structure function at small x. The cross section for vector meson production are shown to be experimentally accessible for moderate values of Q^2. This is sufficient to probe the nature of the hard pomeron which has recently been proposed.Comment: some changes in style, physics unchanged, final version to appear in Phys.Rev.D, LaTeX2e, graphicx package, 15 eps-figures, 15p

Gamma(*)Gamma(*) reaction at high energies

The energy available for gamma(*)gamma(*) physics at LEP2 is opening a new window on the study of diffractive phenomena, both non-perturbative and perturbative. We discuss some of the uncertainties and problems connected with the experimental measurements and their interpretation.Comment: 6 pages, 6 figures, submitted to proceedings of the Durham Collider Workshop, 22-26 September 199

Local endothelial complement activation reverses endothelial quiescence, enabling t-cell homing, and tumor control during t-cell immunotherapy.

Cancer immunotherapy relies upon the ability of T cells to infiltrate tumors. The endothelium constitutes a barrier between the tumor and effector T cells, and the ability to manipulate local vascular permeability could be translated into effective immunotherapy. Here, we show that in the context of adoptive T cell therapy, antitumor T cells, delivered at high enough doses, can overcome the endothelial barrier and infiltrate tumors, a process that requires local production of C3, complement activation on tumor endothelium and release of C5a. C5a, in turn, acts on endothelial cells promoting the upregulation of adhesion molecules and T-cell homing. Genetic deletion of C3 or the C5a receptor 1 (C5aR1), and pharmacological blockade of C5aR1, impaired the ability of T cells to overcome the endothelial barrier, infiltrate tumors, and control tumor progression in vivo, while genetic chimera mice demonstrated that C3 and C5aR1 expression by tumor stroma, and not leukocytes, governs T cell homing, acting on the local endothelium. In vitro, endothelial C3 and C5a expressions were required for endothelial activation by type 1 cytokines. Our data indicate that effective immunotherapy is a consequence of successful homing of T cells in response to local complement activation, which disrupts the tumor endothelial barrier

Confining QCD Strings, Casimir Scaling, and a Euclidean Approach to High-Energy Scattering

We compute the chromo-field distributions of static color-dipoles in the fundamental and adjoint representation of SU(Nc) in the loop-loop correlation model and find Casimir scaling in agreement with recent lattice results. Our model combines perturbative gluon exchange with the non-perturbative stochastic vacuum model which leads to confinement of the color-charges in the dipole via a string of color-fields. We compute the energy stored in the confining string and use low-energy theorems to show consistency with the static quark-antiquark potential. We generalize Meggiolaro's analytic continuation from parton-parton to gauge-invariant dipole-dipole scattering and obtain a Euclidean approach to high-energy scattering that allows us in principle to calculate S-matrix elements directly in lattice simulations of QCD. We apply this approach and compute the S-matrix element for high-energy dipole-dipole scattering with the presented Euclidean loop-loop correlation model. The result confirms the analytic continuation of the gluon field strength correlator used in all earlier applications of the stochastic vacuum model to high-energy scattering.Comment: 65 pages, 13 figures, extended and revised version to be published in Phys. Rev. D (results unchanged, 2 new figures, 1 new table, additional discussions in Sec.2.3 and Sec.5, new appendix on the non-Abelian Stokes theorem, old Appendix A -> Sec.3, several references added

Heavy Quarkonia: Wilson Area Law, Stochastic Vacuum Model and Dual QCD

The $Q \bar{Q}$ semirelativistic interaction in QCD can be simply expressed in terms of the Wilson loop and its functional derivatives. In this approach we present the $Q \bar{Q}$ potential up to order $1/m^2$ using the expressions for the Wilson loop given by the Wilson Minimal Area Law (MAL), the Stochastic Vacuum Model (SVM) and Dual QCD (DQCD). We confirm the original results given in the different frameworks and obtain new contributions. In particular we calculate up to order $1/m^2$ the complete velocity dependent potential in the SVM. This allows us to show that the MAL model is entirely contained in the SVM. We compare and discuss also the SVM and the DQCD potentials. It turns out that in these two very different models the spin-orbit potentials show up the same leading non-perturbative contributions and 1/r corrections in the long-range limit.Comment: 29 pages, revtex, 1 figure(fig1.ps); replaced with the last version that will appear in Phys. Rev. D (1March 1997); few misprints correcte