57 research outputs found

    Mejora de la composición corporal en una mujer con sobrepeso y en transición menopáusica mediante la combinación de ejercicio y nutrición

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    Programa de entrenamiento para la mejora de la composición corporal en una mujer de 54 años, sedentaria, sin patologías asociadas, perimenopáusica mediante la combinación de ejercicio físico y nutriciónMáster en entrenamiento personal. VIII Edición 2018/201

    Análisis del artículo 29 de la Constitución Política de los Estados Unidos Mexicanos como un mecanismo jurídico para agotar la facultad discrecional del ejecutivo federal frente eventos catastróficos

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    Las obligaciones están inherentes en los súbditos del Estado cuando realizan acciones u omisiones que prevea la norma jurídica en los casos en concreto, esto es, el súbdito del Estado deberá contribuir al gasto público para solventar dichas acciones que puedan prevalecer y preverse en las respectivas Leyes de Ingresos y de Egresos de una nación. La problemática radica en cuanto a la efectiva interpretación y aplicación de los Principios de Proporcionalidad y de Equidad toda vez que las leyes tributarias son de aplicación estricta, los confictos que se susciten en la interpretación y la aplicación efectiva, traen menos cabo al mismo Estado y contrae una obligación conflictual económica, administrativa, fiscal, laboral y contablemente hablando a una empresa. Para que esta situación no prevalezca y puedan resolverse a mejor puerto los conflictos hacendarios, estudiaremos los efectos inherentes de la política económica implementada desde la óptica contributiva en el reflejo de esta compleja pandemia con la finalidad de aplicarlo y ejercitarlo como política pública y su efectiva conciencia cívica-contributiva en beneficio del contribuyente y de la efectiva recaudación económica para el Estado

    Resource and reserve calculation in seam-shaped mineral deposits; a new approach: “The pentahedral method”

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    In recent years, the introduction of specific software for the evaluation of geological resources and mineral reserves has increased significantly thanks to the use of block models capable of working with large databases and applicable to virtually all types of deposits. It is only in layered, tabular-shaped deposits where the use of block models poses certain drawbacks, not only in terms of visual representation but also during the process of interpolation. Other calculation methods for tabular bodies such as sections, polygons, and triangles work with 2D projections but not with 3D. The “Pentahedral” method described here is undoubtedly an innovative method that allows work to always be conducted in 3D, providing a fairly accurate representation of tabular bodies and making it possible to carry out calculations of resources and reserves using any interpolation method. It is demonstrated with figures and tables of the Carlés mineral deposit, a well-developed exoskarn gold deposit in northwestern Spain (Asturias) where the authors have worked extensively. The pentahedral method takes into account not only geological and stratigraphic data from the model interpolation, but also mining concepts such as “minimum thickness,” related to the minimum seam size that can be economically and technically mined, and “overbreak,” related to the dilution effect that appears during the mining process due to over-excavation

    Aprender ciencia investigando, colaborando y mentorizando, en un entorno interdisciplinar

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    Depto. de Física de la Tierra y AstrofísicaDepto. de Mineralogía y PetrologíaFac. de Ciencias FísicasFac. de Ciencias GeológicasFALSEsubmitte

    In vivo cholinergic basal forebrain degeneration and cognition in Parkinson's disease: Imaging results from the COPPADIS study

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    Introduction: We aimed to assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in Parkinson’s disease (PD) without dementia. Methods: The study included a total of 180 non-demented PD patients and 45 healthy controls, who underwent structural MRI acquisitions and standardized neurocognitive assessment through the PD-Cognitive Rating Scale (PD-CRS) within the multicentric COPPADIS-2015 study. A subset of 73 patients also had Diffusion Tensor Imaging (DTI) acquisitions. Volumetric and microstructural (mean diffusivity, MD) indices of CBF degeneration were automatically extracted using a stereotactic CBF atlas. For comparison, we also assessed multimodal indices of hippocampal degeneration. Associations between imaging measures and cognitive performance were assessed using linear models. Results: Compared to controls, CBF volume was not significantly reduced in PD patients as a group. However, across PD patients lower CBF volume was significantly associated with lower global cognition (PD-CRStotal: r =0.37, p <0.001), and this association remained significant after controlling for several potential confounding variables (p =0.004). Analysis of individual item scores showed that this association spanned executive and memory domains. No analogue cognition associations were observed for CBF MD. In covariate-controlled models, hippocampal volume was not associated with cognition in PD, but there was a significant association for hippocampal MD (p =0.02). Conclusions: Early cognitive deficits in PD without dementia are more closely related to structural MRI measures of CBF degeneration than hippocampal degeneration. In our multicentric imaging acquisitions, DTI-based diffusion measures in the CBF were inferior to standard volumetric assessments for capturing cognition- relevant changes in non-demented PD

    Impact of the first wave of the SARS-CoV-2 pandemic on the outcome of neurosurgical patients: A nationwide study in Spain

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    Objective To assess the effect of the first wave of the SARS-CoV-2 pandemic on the outcome of neurosurgical patients in Spain. Settings The initial flood of COVID-19 patients overwhelmed an unprepared healthcare system. Different measures were taken to deal with this overburden. The effect of these measures on neurosurgical patients, as well as the effect of COVID-19 itself, has not been thoroughly studied. Participants This was a multicentre, nationwide, observational retrospective study of patients who underwent any neurosurgical operation from March to July 2020. Interventions An exploratory factorial analysis was performed to select the most relevant variables of the sample. Primary and secondary outcome measures Univariate and multivariate analyses were performed to identify independent predictors of mortality and postoperative SARS-CoV-2 infection. Results Sixteen hospitals registered 1677 operated patients. The overall mortality was 6.4%, and 2.9% (44 patients) suffered a perioperative SARS-CoV-2 infection. Of those infections, 24 were diagnosed postoperatively. Age (OR 1.05), perioperative SARS-CoV-2 infection (OR 4.7), community COVID-19 incidence (cases/10 5 people/week) (OR 1.006), postoperative neurological worsening (OR 5.9), postoperative need for airway support (OR 5.38), ASA grade =3 (OR 2.5) and preoperative GCS 3-8 (OR 2.82) were independently associated with mortality. For SARS-CoV-2 postoperative infection, screening swab test <72 hours preoperatively (OR 0.76), community COVID-19 incidence (cases/10 5 people/week) (OR 1.011), preoperative cognitive impairment (OR 2.784), postoperative sepsis (OR 3.807) and an absence of postoperative complications (OR 0.188) were independently associated. Conclusions Perioperative SARS-CoV-2 infection in neurosurgical patients was associated with an increase in mortality by almost fivefold. Community COVID-19 incidence (cases/10 5 people/week) was a statistically independent predictor of mortality. Trial registration number CEIM 20/217
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