Frontiers in Immunology

Not AvailableEmerging, infectious diseases in shrimp like acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus and mortality caused by other Vibrio species such as Vibrio harveyi are worldwide related to huge economic losses in industrial shrimp production. As a strategy to prevent disease outbreaks, a plant-based phenolic compound could be used as a biocontrol agent. Here, using the brine shrimp (Artemia franciscana) as a model system, we showed that phloroglucinol treatment of the parental animals at early life stages resulted in transgenerational inherited increased resistance in their progeny against biotic stress, i.e., bacteria (V. parahaemolyticus AHPND strain and V. harveyi) and abiotic stress, i.e., lethal heat shock. Increased resistance was recorded in three subsequent generations. Innate immune-related gene expression profiles and potential epigenetic mechanisms were studied to discover the underlying protective mechanisms. Our results showed that phloroglucinol treatment of the brine shrimp parents significantly (P < 0.05) enhanced the expression of a core set of innate immune genes (DSCAM, proPO, PXN, HSP90, HSP70, and LGBP) in subsequent generations. We also demonstrated that epigenetic mechanisms such as DNA methylation, m6A RNA methylation, and histone acetylation and methylation (active chromatin marker i.e., H3K4Me3, H3K4me1, H3K27me1, H3 hyperacetylation, H3K14ac and repression marker, i.e., H3K27me3, H4 hypoacetylation) might play a role in regulation of gene expression leading toward the observed transgenerational inheritance of the resistant brine shrimp progenies. To our knowledge, this is the first report on transgenerational inheritance of a compound-induced robust protected phenotype in brine shrimp, particularly protected against AHPND caused by V. parahaemolyticus and vibriosis caused by V. harveyi. Results showed that epigenetic reprogramming is likely to play a role in the underlying mechanism

Does air quality matter for mutual funds' tracking errors? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Finance at Massey University, Auckland, New Zealand

Social science literature documents that air quality affects the cognitive dissonance of market participants including retail investors. In this paper, we examine the effect of air pollution on professional investors: mutual fund managers. We find air pollution affects managers’ cognitive performance and behaviour bias, resulting in higher funds’ tracking errors. In addition, we identify factors, which can improve fund managers’ cognitive abilities, reducing the impact of air pollution

Sundarbans mangrove deltaic system – An overview of its biodiversity with special reference to fish diversity

World heritage site-Sundarbans were declared as the world’s 560th Ramsar Wetlands site in 1992. Sundarbans ecosystem supports rich fisheries diversity and also natural biodiversity hot spot, because it is natural habitat of many endangered species. The Sundarbans is a home to a variety of faunal species, the total of 1586 species has been recorded which includes 481 Vertebrate species (30%), 1104 Invertebrate species (70%). Mangroves are the nursery and breeding grounds for several commercially important species of aquatic fauna like fish, shrimps and prawns etc. Mangrove ecosystems are of great ecological significance in the tropical and sub-tropical coast. Sundarbans mangrove provides a variety of ecosystem services. However, the Sundarban mangrove forest is the most threatened habitats in the world, increased population with few alternative livelihood opportunities poses a serious threat as it is the main cause of mangrove destruction. The total value of Sundarbans is not recognized and therefore often neglected in development planning. As a result Sundarbans conservation issue is getting less importance at the national level. The study reveals that major ecosystem services of Sundarbans are timber, fuel wood, fish, ecotourism, cyclone and storm protection, biodiversity, and habitat for flora and fauna. Timber, fuel wood and fish are more economical provisioning services in Sundarbans. It is noticed that there is decreasing tendency of overall revenue collection from the mangrove over the period of 2001-02 to 2009-10. The attention from national and international communities is needed for sustainable management and conservation of the Sundarbans. The study suggests that further research on total economic value of Sundarbans is needed for providing comprehensive scientific information for policy as well as for decision makers

Threats faced by brown rot of potato in Bangladesh

Potato is the most important root crop in Bangladesh. The field production is very much lower compared to other developed countries. Pests and diseases hampered the production due to the prevailing climatic condition, which favors the development in Bangladesh of specific diseases. Among them Brown rot (Ralstonia solanacearum) is the most alarming disease at present and previous time. The major areas of Bangladesh have faced many hampers on this disease. The potato growers and businessmen of Bangladesh are facing much problems on this disease especially in case of export to other countries as Russia, Malaysia, Singapore, Indonesia, Sri Lanka, Thailand, Hong Kong, Vietnam, Maldives, Turkey, Azerbaijan, Ethiopia and Nigeria. But during last year Russian Government banned import potatoes from Bangladesh. So, from these perspectives, this concept paper was studied to evaluate the most appropriate status of this disease caused by organisms and its best control strategies to impart better production thinking for Bangladeshi potato growers, exporters and other related personnels

Organoleptic and grain quality traits of aromatic rice varieties as influenced by supplementation of Zn and 2-acetyl-1-pyrroline

Aromatic rice fetches premium prices in world markets due to its pleasant smell and enchanting flavor. In Bangladesh, the quality of aromatic rice is much inferior than those of other rice growing countries because of lack of improved variety and judicious agronomic management. Selection of appropriate variety and supplementation zinc (Zn) and 2-acetyl-1-pyrroline (2-AP) can improve the aroma. The present study exhibited the effects of 2-AP and Zn supplementation on yield and quality of aromatic rice. Two well-known aromatic cultivars, BRRI dhan80 and BRRI dhan34, were cultured separately in pot supplemented with 2-AP and Zn. The results showed that supplementation of 2-AP and /or Zn along with conventional practices had significant effects on organoleptic and some quality parameters studied in this study. The concentration of 2AP and Zn in rice grain increased with increasing their application rate. Additionally, grain 2-AP concentrations were significantly and positively correlated with organoleptic characters. Interactions of both these elements with the complex process of 2-AP formation remain to be explored

An observational study comparing and non-surgical treatment with surgical treatment for chronic anal fissures

Background: Chronic anal fissure is a common benign anorectal condition that causes significant morbidity. Symptoms consist primarily of pain and bleeding during defecation. Fissures are predominantly located in the posterior midline, but 25% of women and 8% of men have anterior fissures. Aims and Objectives: The aim of the study is to determine the outcome of various nonsurgical therapy for chronic anal fissure and comparison with the outcome of surgical treatment. Materials and Methods: This study was a non-randomized and observational study. All patients referred to the department of general surgery between December 2012 and November 2014 for a chronic anal fissure were included in the study, above the age of 12 years, and diagnosed to have anal fissure (Both Acute and Chronic) were included in the study. Results: Seventy-nine patients (91.9%) were having symptoms of pain; this pain was persistent for hours after defecation in 67 (78%) patients. Seventy-one (82.6%) patients complained of at least one episode of bleeding per Anum, other symptoms were perianal lump (10.5%), perianal itching (23.3%), and perianal discharge (30.2%). The examination findings of these patients revealed that 81 patients (94%) had developed sentinelpiles subsequently and anal fissure with visible fibers of underlying muscle were seen in 9 (10.5%) patients. Conclusion: Chronic anal fissures can be simply and effectively treated medically without the risk of incontinence associated with sphincterotomy. Topical nifedipine and botulinum toxin injections are an excellent combination, associated with a low recurrence rate and minimal side effects

Growth and Hemato-Immunological Response to Dietary i-Carrageenan in Labeo rohita (Hamilton, 1822) Juveniles

The study was performed over a period of 60 days to evaluate the effect of dietary carrageenan on growth, hematology, biochemistry, and innate immunity in rohu Labeo rohita. A basal diet supplemented with iota (i)Carrageenan at 5, 10 and 20g/kg was fed to three different groups of fish for 60 days. The fish were examined 15, 30, 45, and 60 days after commencement of the study. Parameters for growth (absolute growth, specific growth rate, and percentage weight gain), hematology (total erythrocyte count, total leucocyte count, thrombocyte count and hemoglobin value), biochemistry (total serum protein, albumin, globulin and albuminglobulin ratio), and innate immunity (nitroblue tetrazolium NBT, and myeloperoxidase MPO, activity) were monitored to assess the effect of the iCarrageenan based diet in L. rohita. All the parameters examined (growth, hematology, biochemistry, and innate immunity) increased significantly (P<0.05) in carrageenan-fed groups compared to the control group. However, the highest values for those parameters were found on the 60th day in the group which was fed a 10 g/kg i-Carrageenan diet. The study suggests that a 10 g/kg diet of i-carrageenan enhances immunity and the overall health status in L. rohita

Phloroglucinol treatment induces transgenerational epigenetic inherited resistance against Vibrio infections and thermal stress in a brine shrimp (Artemia franciscana) model

Emerging, infectious diseases in shrimp like acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus and mortality caused by other Vibrio species such as Vibrio harveyi are worldwide related to huge economic losses in industrial shrimp production. As a strategy to prevent disease outbreaks, a plant-based phenolic compound could be used as a biocontrol agent. Here, using the brine shrimp (Artemia franciscana) as a model system, we showed that phloroglucinol treatment of the parental animals at early life stages resulted in transgenerational inherited increased resistance in their progeny against biotic stress, i.e., bacteria (V. parahaemolyticus AHPND strain and V. harveyi) and abiotic stress, i.e., lethal heat shock. Increased resistance was recorded in three subsequent generations. Innate immune-related gene expression profiles and potential epigenetic mechanisms were studied to discover the underlying protective mechanisms. Our results showed that phloroglucinol treatment of the brine shrimp parents significantly (P < 0.05) enhanced the expression of a core set of innate immune genes (DSCAM, proPO, PXN, HSP90, HSP70, and LGBP) in subsequent generations. We also demonstrated that epigenetic mechanisms such as DNA methylation, m6A RNA methylation, and histone acetylation and methylation (active chromatin marker i.e., H3K4Me3, H3K4me1, H3K27me1, H3 hyperacetylation, H3K14ac and repression marker, i.e., H3K27me3, H4 hypoacetylation) might play a role in regulation of gene expression leading toward the observed transgenerational inheritance of the resistant brine shrimp progenies. To our knowledge, this is the first report on transgenerational inheritance of a compound-induced robust protected phenotype in brine shrimp, particularly protected against AHPND caused by V. parahaemolyticus and vibriosis caused by V. harveyi. Results showed that epigenetic reprogramming is likely to play a role in the underlying mechanism