163 research outputs found
Effects of interdot dipole coupling in mesoscopic epitaxial Fe(100) dot arrays
The domain structure and the coercivity of epitaxial Fe(100) circular dot arrays of different diameters and separations have been studied using magnetic force microscopy (MFM) and focused magneto-optical Kerr effect (MOKE). The MFM images of the 1 ”m diameter single domain dot arrays show direct evidence of strong interdot dipole coupling when the separation is reduced down to 0.1 ”m. The coercivity of the dots is also found to be dependent on the separation, indicating the effect of the interdot dipole coupling on the magnetization reversal process
Predictions from Quantum Cosmology
The world view suggested by quantum cosmology is that inflating universes
with all possible values of the fundamental constants are spontaneously created
out of nothing. I explore the consequences of the assumption that we are a
`typical' civilization living in this metauniverse. The conclusions include
inflation with an extremely flat potential and low thermalization temperature,
structure formation by topological defects, and an appreciable cosmological
constant.Comment: (revised version), 15 page
A calibration method for broad-bandwidth cavity enhanced absorption spectroscopy performed with supercontinuum radiation
An efficient calibration method has been developed for broad-bandwidth cavity enhanced absorption spectroscopy. The calibration is performed using phase shift cavity ring-down spectroscopy, which is conveniently implemented through use of an acousto-optic tunable filter (AOTF). The AOTF permits a narrowband portion of the SC spectrum to be scanned over the full high-reflectivity bandwidth of the cavity mirrors. After calibration the AOTF is switched off and broad-bandwidth CEAS can be performed with the same light source without any loss of alignment to the set-up. We demonstrate the merits of the method by probing transitions of oxygen molecules O-2 and collisional pairs of oxygen molecules (O-2)(2) in the visible spectral range
Continuous wave optical parametric oscillator for quartz-enhanced photoacoustic trace gas sensing
A continuous wave optical parametric oscillator, generating up to 300 mW idler output in the 3â4 ÎŒm wavelength region, and pumped by a fiber-amplified DBR diode laser is used for trace gas detection by means of quartz-enhanced photoacoustic spectroscopy (QEPAS). Mode-hop-free tuning of the OPO output over 5.2 cm-1 and continuous spectral coverage exceeding 16.5 cm-1 were achieved via electronic pump source tuning alone. Online monitoring of the idler wavelength, with feedback to the DBR diode laser, provided an automated closed-loop control allowing arbitrary idler wavelength selection within the pump tuning range and locking of the idler wavelength with a stability of 1.7Ă10-3 cm-1 over at least 30 min.\ud
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Using this approach, we locked the idler wavelength at an ethane absorption peak and obtained QEPAS data to verify the linear response of the QEPAS signal at different ethane concentrations (100 ppbv-20 ppmv) and different power levels. The detection limit for ethane was determined to be 13 ppbv (20 s averaging), corresponding to a normalized noise equivalent absorption coefficient of 4.4Ă10-7 cm-1â W/Hz1/2
The power of suggestion: examining the impact of presence or absence of shared first language in the antenatal clinic
© 2019 Foundation for the Sociology of Health & Illness Healthcare encounters involving participants from diverse linguistic backgrounds are becoming more common due to the globalisation of health care and increasing migration levels. Research suggests that this diversity has a significant impact on health outcomes; however less is known about how it is managed in the actual consultation process. This article presents an analysis of antenatal screening consultations video recorded in Hong Kong, using conversation analysis. We consider how the use of a second or subsequent language impacts on these consultations, and on discussions and decisions about further action. The presence or absence of shared first language did not appear to affect the extent to which particular courses of action were promoted or recommended. Recommendations were a common occurrence across consultations with and without shared first language. However, we argue that the routine use of recommendations can be consequential, as second language speakers may have more limited resources to interrogate or contest these. This finding has implications for the ability for professionals to maximise patient involvement in decision-making
A perspective on the landscape problem
I discuss the historical roots of the landscape problem and propose criteria
for its successful resolution. This provides a perspective to evaluate the
possibility to solve it in several of the speculative cosmological scenarios
under study including eternal inflation, cosmological natural selection and
cyclic cosmologies.Comment: Invited contribution for a special issue of Foundations of Physics
titled: Forty Years Of String Theory: Reflecting On the Foundations. 31
pages, no figure
What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis?:A systematic review
Primordial black holes in braneworld cosmologies: astrophysical constraints
In two recent papers we explored the modifications to primordial black hole
physics when one moves to the simplest braneworld model, Randall--Sundrum type
II. Both the evaporation law and the cosmological evolution of the population
can be modified, and additionally accretion of energy from the background can
be dominant over evaporation at high energies. In this paper we present a
detailed study of how this impacts upon various astrophysical constraints,
analyzing constraints from the present density, from the present high-energy
photon background radiation, from distortion of the microwave background
spectrum, and from processes affecting light element abundances both during and
after nucleosynthesis. Typically, the constraints on the formation rate of
primordial black holes weaken as compared to the standard cosmology if black
hole accretion is unimportant at high energies, but can be strengthened in the
case of efficient accretion.Comment: 17 pages RevTeX4 file with three figures incorporated; final paper in
series astro-ph/0205149 and astro-ph/0208299. Minor changes to match version
accepted by Physical Review
Cavity-enhanced direct frequency comb spectroscopy
Cavity-enhanced direct frequency comb spectroscopy combines broad spectral
bandwidth, high spectral resolution, precise frequency calibration, and
ultrahigh detection sensitivity, all in one experimental platform based on an
optical frequency comb interacting with a high-finesse optical cavity. Precise
control of the optical frequency comb allows highly efficient, coherent
coupling of individual comb components with corresponding resonant modes of the
high-finesse cavity. The long cavity lifetime dramatically enhances the
effective interaction between the light field and intracavity matter,
increasing the sensitivity for measurement of optical losses by a factor that
is on the order of the cavity finesse. The use of low-dispersion mirrors
permits almost the entire spectral bandwidth of the frequency comb to be
employed for detection, covering a range of ~10% of the actual optical
frequency. The light transmitted from the cavity is spectrally resolved to
provide a multitude of detection channels with spectral resolutions ranging
from a several gigahertz to hundreds of kilohertz. In this review we will
discuss the principle of cavity-enhanced direct frequency comb spectroscopy and
the various implementations of such systems. In particular, we discuss several
types of UV, optical, and IR frequency comb sources and optical cavity designs
that can be used for specific spectroscopic applications. We present several
cavity-comb coupling methods to take advantage of the broad spectral bandwidth
and narrow spectral components of a frequency comb. Finally, we present a
series of experimental measurements on trace gas detections, human breath
analysis, and characterization of cold molecular beams.Comment: 36 pages, 27 figure
Genetically Determined Height and Risk of Non-hodgkin Lymphoma
Although the evidence is not consistent, epidemiologic studies have suggested that taller adult height may be associated with an increased risk of some non-Hodgkin lymphoma (NHL) subtypes. Height is largely determined by genetic factors, but how these genetic factors may contribute to NHL risk is unknown. We investigated the relationship between genetic determinants of height and NHL risk using data from eight genome-wide association studies (GWAS) comprising 10,629 NHL cases, including 3,857 diffuse large B-cell lymphoma (DLBCL), 2,847 follicular lymphoma (FL), 3,100 chronic lymphocytic leukemia (CLL), and 825 marginal zone lymphoma (MZL) cases, and 9,505 controls of European ancestry. We evaluated genetically predicted height by constructing polygenic risk scores using 833 height-associated SNPs. We used logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI) for association between genetically determined height and the risk of four NHL subtypes in each GWAS and then used fixed-effect meta-analysis to combine subtype results across studies. We found suggestive evidence between taller genetically determined height and increased CLL risk (OR = 1.08, 95% CI = 1.00\u20131.17, p = 0.049), which was slightly stronger among women (OR = 1.15, 95% CI: 1.01\u20131.31, p = 0.036). No significant associations were observed with DLBCL, FL, or MZL. Our findings suggest that there may be some shared genetic factors between CLL and height, but other endogenous or environmental factors may underlie reported epidemiologic height associations with other subtypes
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