Retrieval of optical and microphysical properties of transported Saharan dust over Athens and Granada based on multi-wavelength Raman lidar measurements: Study of the mixing processes

In this paper we extract the aerosol microphysical properties for a collection of mineral dust cases measured by multi-wavelength depolarization Raman lidar systems located at the National Technical University of Athens (NTUA, Athens, Greece) and the Andalusian Institute for Earth System Research (IISTA-CEAMA, Granada, Spain). The lidar-based retrievals were carried out with the Spheroidal Inversion eXperiments software tool (SphInX) developed at the University of Potsdam (Germany). The software uses regularized inversion of a two-dimensional enhancement of the Mie model based on the spheroid-particle approximation with the aspect ratio determining the particle shape. The selection of the cases was based on the transport time from the source regions to the measuring sites. The aerosol optical depth as measured by AERONET ranged from 0.27 to 0.54 (at 500 nm) depending on the intensity of each event. Our analysis showed the hourly mean particle linear depolarization ratio and particle lidar ratio values at 532 nm ranging from 11 to 34% and from 42 to 79 sr respectively, depending on the mixing status, the corresponding air mass pathways and their transport time. Cases with shorter transport time showed good agreement in terms of the optical and SphInX-retrieved microphysical properties between Athens and Granada providing a complex refractive index value equal to 1.4 + 0.004i. On the other hand, the results for cases with higher transport time deviated from the aforementioned ones as well as from each other, providing, in particular, an imaginary part of the refractive index ranging from 0.002 to 0.005. Reconstructions of two-dimensional shape-size distributions for each selected layer showed that the dominant effective particle shape was prolate with diverse spherical contributions. The retrieved volume concentrations reflect overall the intensity of the episodes.Spanish Ministry of Sciences, Innovation and Universities through project CGL2016-81092,Spanish Ministry of Education, Culture and Sports through grant FPU14/0368

Nitrogen budgets for Boro rice (Oryza sativa L.) fields in Bangladesh

Nitrogen (N) budgets are a valuable tool for improving N efficiency because they assess the size and interactions of various N pools, as well as their gains from the atmosphere and losses to the environment. To understand the impact of changes in management practice upon a farming system, it is necessary to increase the complexity of the N budgets to include N flows. Therefore, a project was undertaken in lowland irrigated systems of Bangladesh to study the N budgets of Boro rice grown under ecological and conventional farming systems in four locations (Dhamrai, Daulatpur, Gabtali and Shibgonj) in Bangladesh in 2007 and 2008. The N budget focuses on the total-N inputs and losses of the entire system. The budgets were negative for both farming systems in both years. Overall, ecological farming system produced a less negative balance in both years (−6 to −36 kg N ha−1 in 2007 and −76 to −160 kg N ha−1 in 2008) than the conventional farming system (−28 to −80 kg N ha−1 in 2007 and −91 to −157 kg N ha−1 in 2008). Nitrogen balance studies highlighted losses of mineral N (26–53 kg N ha−1) which accumulated prior to irrigation and also losses due to N removal (13–28 kg N ha−1) by weeds. Beneficial impacts of ecological farming on N balances were observed due to the elimination of fertiliser N loss (30–133 kg N ha−1). The difference between conventional and ecological management reflects the high losses of fertiliser N under conventional management. These fertiliser N losses reflect the low agronomic efficiency of N fertiliser. An understanding of various N losses and their consequences is important to provide a basis for developing efficient N management strategies in boro rice. These N budgets can be used to improve or design new technologies that tackle soil fertility management problems and also can help improve the financial performance of the farmers. Soil N budgets will continue to challenge agricultural scientists by slowly revealing fundamental principles. By understanding these principles and the factors influencing them, basic and applied scientists will have a stronger foundation for improving N use efficiency and concurrently reducing N losses to the environment

A model of ice-marginal sediment-landform development at Lake Tekapo, Southern Alps, New Zealand

The extent of the Southern Alps icefield in New Zealand is well-constrained chronologically for the last glacial cycle. The sediment-landform imprint of this glacial system, however, offers insight into ice-marginal processes that chronological control cannot. We present the first detailed investigation of sediments along the southwestern shores of Lake Tekapo, South Island. We identify seven lithofacies, from which a five-stage palaeoglaciological reconstruction of depositional and glaciotectonic events is proposed: (i) ice-marginal advance and deposition of outwash gravels in lithofacies (LF) 1; (ii) ice-marginal recession and the development of an ice-contact lake, manifest in rhythmite deposition and iceberg rafting of dropstones (LF 2), followed by a depositional hiatus; (iii) ice-marginal recession recorded in ice-proximal aggradation of glaciofluvial hyperconcentrated flows (LFs 3, 4); (iv) ice-marginal advance documented by glaciotectonic disturbance and localized hydrofracturing, coeval with the deposition of delta foresets and a subglacial diamicton/till (LFs 5, 6); (v) final stages of ice-marginal recession and deposition of outwash gravels in LF 7. Two infrared stimulated luminescence ages were obtained from the glaciolacustrine sediments and, whilst the dating has some limitations, the sediments pre-date both the global and local Last Glacial Maximum. Overall, this sequence, consistent with sediment fills recorded elsewhere across South Island, suggests recurrence of processes from different glacial advances and the role of topographic constraints on maintaining lake positions

Klebsiella pneumoniae targets an EGF receptor-dependent pathway to subvert inflammation

[eng] The NF-kB transcriptional factor plays a key role governing the activation of immune responses. Klebsiella pneumoniae is an important cause of community-acquired and nosocomial pneumonia. Evidence indicates that K. pneumoniae infections are characterized by lacking an early inflammatory response. Recently, we have demonstrated that Klebsiella antagonizes the activation of NF-kB via the deubiquitinase CYLD. In this work, by applying a high-throughput siRNA gain-of-function screen interrogating the human kinome, we identified 17 kinases that when targeted by siRNA restored IL-1b-dependent NF-kB translocation in infected cells. Further characterization revealed that K. pneumoniae activates an EGF receptor (EGFR)- phosphatidylinositol 3-OH kinase (PI3K)-AKT-PAK4-ERK-GSK3b signalling pathway to attenuate the cytokine-dependent nuclear translocation of NF-kB. Our data also revealed that CYLD is a downstream effector of K. pneumoniae-induced EGFR-PI3K-AKT-PAK4-ERK-GSK3b signalling pathway. Our efforts to identify the bacterial factor(s) responsible for EGFR activation demonstrate that a capsule (CPS) mutant did not activate EGFR hence suggesting that CPS could mediate the activation of EGFR. Supporting this notion, purified CPS did activate EGFR as well as the EGFR-dependent PI3K-AKT-PAK4-ERK-GSK3b signalling pathway. CPS-mediated EGFR activation was dependent on a TLR4-MyD88-c-SRC-dependent pathway. Several promising drugs have been developed to antagonize this cascade.We propose that agents targeting this signalling pathway might provide selective alternatives for the management of K. pneumoniae pneumonias