20,903 research outputs found
Monosynaptic connections between pairs of spiny stellate cells in layer 4 and pyramidal cells in layer 5A indicate that lemniscal and paralemniscal afferent pathways converge in the infragranular somatosensory cortex.
Monosynaptic interlaminar connections between spiny stellate cells in layer 4 (L4), the main cortical recipient layer for thalamic projections, and pyramidal cells in layer 5A (L5A), one of the main cortical output layers, were examined anatomically and functionally by paired recordings in acute brain slices. The somata of pairs forming interlaminar L4-to-L5A connections were located predominantly close to or directly under the barrel-septum wall in layer 4. Superposition of spiny stellate axon arbors and L5A pyramidal cell dendritic arbors suggested an innervation domain underneath an L4 barrel wall. Functionally, the L4-to-L5A connections were of high reliability and relatively low efficacy, with a unitary EPSP amplitude of 0.6 mV, and the connectivity was moderately high (one in seven pairs tested was connected). The EPSP amplitude was weakly depressing (paired-pulse ratio of approximately 0.8) during repetitive presynaptic action potentials at 10 Hz. The existence of Monosynaptic L4-to-L5A connections indicates that the specific 'lemniscal' thalamic input from the ventro-basal nucleus of the thalamus to the cortex and the more unspecific 'paralemniscal' afferent thalamic projections from the posterior medial nucleus of the thalamus merge already at an initial stage of cortical signal processing. These Monosynaptic connections establish a Monosynaptic coupling of the input to the cortex and its output, thereby effectively bypassing the supragranular layers
Advanced passive communication satellite systems comparison studies. Volume 1 - Summary Final report
Passive communication satellites feasibility for Comsat system - Vol.
Advanced passive communication satellite systems comparison studies. Volume 2 - Technical discussion Final report
Passive communication satellites feasibility for Comsat system - Vol.
Translational cooling and storage of protonated proteins in an ion trap at subkelvin temperatures
Gas-phase multiply charged proteins have been sympathetically cooled to
translational temperatures below 1 K by Coulomb interaction with laser-cooled
barium ions in a linear ion trap. In one case, an ensemble of 53 cytochrome c
molecules (mass ~ 12390 amu, charge +17 e) was cooled by ~ 160 laser-cooled
barium ions to less than 0.75 K. Storage times of more than 20 minutes have
been observed and could easily be extended to more than an hour. The technique
is applicable to a wide variety of complex molecules.Comment: same version as published in Phys. Rev.
The Hospitals/Residents Problem with Couples: complexity and integer programming models
The Hospitals / Residents problem with Couples (hrc) is a generalisation of the classical Hospitals / Residents problem (hr) that is important in practical applications because it models the case where couples submit joint preference lists over pairs of (typically geographically close) hospitals. In this paper we give a new NP-completeness result for the problem of deciding whether a stable matching exists, in highly restricted instances of hrc, and also an inapproximability bound for finding a matching with the minimum number of blocking pairs in equally restricted instances of hrc. Further, we present a full description of the first Integer Programming model for finding a maximum cardinality stable matching in an instance of hrc and we describe empirical results when this model applied to randomly generated instances of hrc
A likelihood method to cross-calibrate air-shower detectors
We present a detailed statistical treatment of the energy calibration of
hybrid air-shower detectors, which combine a surface detector array and a
fluorescence detector, to obtain an unbiased estimate of the calibration curve.
The special features of calibration data from air showers prevent unbiased
results, if a standard least-squares fit is applied to the problem. We develop
a general maximum-likelihood approach, based on the detailed statistical model,
to solve the problem. Our approach was developed for the Pierre Auger
Observatory, but the applied principles are general and can be transferred to
other air-shower experiments, even to the cross-calibration of other
observables. Since our general likelihood function is expensive to compute, we
derive two approximations with significantly smaller computational cost. In the
recent years both have been used to calibrate data of the Pierre Auger
Observatory. We demonstrate that these approximations introduce negligible bias
when they are applied to simulated toy experiments, which mimic realistic
experimental conditions.Comment: 10 pages, 7 figure
Review and statistical analysis of the ultrasonic velocity method for estimating the porosity fraction in polycrystalline materials
A review and statistical analysis of the ultrasonic velocity method for estimating the porosity fraction in polycrystalline materials is presented. Initially, a semi-empirical model is developed showing the origin of the linear relationship between ultrasonic velocity and porosity fraction. Then, from a compilation of data produced by many researchers, scatter plots of velocity versus percent porosity data are shown for Al2O3, MgO, porcelain-based ceramics, PZT, SiC, Si3N4, steel, tungsten, UO2,(U0.30Pu0.70)C, and YBa2Cu3O(7-x). Linear regression analysis produced predicted slope, intercept, correlation coefficient, level of significance, and confidence interval statistics for the data. Velocity values predicted from regression analysis for fully-dense materials are in good agreement with those calculated from elastic properties
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