PRÁTICAS ASSISTENCIAIS DE ENFERMAGEM EM UM NÚCLEO DE OSTOMIA: RELATO DE EXPERIÊNCIA

Objective: Report an experience of residents’ nurses during its practices in a core of ostomates. Methods: This study it is an experience report describing aspects experienced by the authors in the period they developed specialized nursing care activities with ostomates and/or urinary incontinence patients. In this sense, such practices occurred in the Regional Center of the West of Paraná Ostomy, between July 28 and August 20, 2014. Results: They were attended 15 patients, 66.7 % were female. Age ranged between 35 and 68 years and 53.3 % of patients was from the host city core. With regard to the type of ostomy, it was found that 80% was colostomy patients. Moreover, there were nursing consultations covering the whole process, delivery of medical and hospital supplies and health education users. In addition, you could attend monthly meeting organized by members (patients). Conclusions: The practical specialized assistance developed by residents, in addition to strengthening scientific knowledge and personal values toward the service to ostomates patients, proved of great importance to the user who had the opportunity to raise subsidies to promoting self-care and improvement in their quality life.Objetivo: Reportar una experiencia de residentes enfermeras durante sus prácticas en un núcleo de ostomizados. Métodos: Este estudio es un relato de experiencia que describe aspectos experimentados por los autores en el período en que se desarrollaron las actividades de cuidado de enfermería especializados con ostomizados y/o pacientes de incontinencia urinaria. En este sentido, estas prácticas tuvieron lugar en el Centro Regional del Oeste de Paraná ostomía, entre el 28 de julio y 20 de agosto 2014. Resultados: Fueron atendidos 15 pacientes, 66,7 % eran mujeres. La edad osciló entre 35 y 68 años y el 53,3 % de los pacientes eran de la base de la ciudad anfitriona. En cuanto al tipo de ostomía, se encontró que el 80 % eran portador de colostomía. Además, no se Enfermería consultas teniendo en cuenta el proceso en su conjunto, la entrega de suministros médicos y hospitalarios y usuarios de educación sanitaria. Además, podríamos asistir a la reunión mensual organizada por los miembros (los pacientes). Conclusión: Asistencia especializada práctica desarrollada por los residentes, además de fortalecer el conocimiento científico y los valores personales en contra del servicio a los pacientes ostomizados, resultó de gran importancia para el usuario que tuvo la oportunidad de aumentar los subsidios para promover el autocuidado y la mejora de su calidad vida. Objetivo: Relatar a experiência vivenciada por enfermeiros residentes durante suas práticas assistenciais em um núcleo de ostomizados. Métodos: Este estudo trata-se de um relato de experiência que descreve aspectos vivenciados pelos autores no período em que desenvolveram atividades de assistência de enfermagem especializada junto a pacientes ostomizados e/ou com incontinência urinária. Nessa direção, as referidas práticas ocorreram no Núcleo Regional de Ostomizados do Oeste do Paraná, entre 28 de julho e 20 de agosto de 2014. Resultados: Foram atendidos 15 pacientes, sendo que 66,7% do gênero feminino. A idade variou entre 35 e 68 anos e 53,3% dos pacientes eram oriundos da cidade-sede do núcleo. No que se refere ao tipo de ostomia, verificou-se que 80% eram portador de colostomia. Outrossim, realizaram-se consultas de Enfermagem contemplando o processo como um todo, entrega de material médico-hospitalar e educação em saúde aos usuários. Além disso, pôde-se participar de encontro mensal promovido pelos associados (pacientes). Conclusões: As práticas assistências especializadas desenvolvidas pelos residentes, além de reforçar os conhecimentos científicos e valores pessoais frente ao atendimento aos pacientes ostomizados, mostraram-se de grande importância ao usuário o qual teve a oportunidade de angariar subsídios para promoção do autocuidado e melhoria em sua qualidade de vida

Genetic Analysis of Floral Symmetry in Van Gogh's Sunflowers Reveals Independent Recruitment of CYCLOIDEA Genes in the Asteraceae

The genetic basis of floral symmetry is a topic of great interest because of its effect on pollinator behavior and, consequently, plant diversification. The Asteraceae, which is the largest family of flowering plants, is an ideal system in which to study this trait, as many species within the family exhibit a compound inflorescence containing both bilaterally symmetric (i.e., zygomorphic) and radially symmetric (i.e., actinomorphic) florets. In sunflower and related species, the inflorescence is composed of a single whorl of ray florets surrounding multiple whorls of disc florets. We show that in double-flowered (dbl) sunflower mutants (in which disc florets develop bilateral symmetry), such as those captured by Vincent van Gogh in his famous nineteenth-century sunflower paintings, an insertion into the promoter region of a CYCLOIDEA (CYC)-like gene (HaCYC2c) that is normally expressed specifically in WT rays is instead expressed throughout the inflorescence, presumably resulting in the observed loss of actinomorphy. This same gene is mutated in two independent tubular-rayed (tub) mutants, though these mutations involve apparently recent transposon insertions, resulting in little or no expression and radialization of the normally zygomorphic ray florets. Interestingly, a phylogenetic analysis of CYC-like genes from across the family suggests that different paralogs of this fascinating gene family have been independently recruited to specify zygomorphy in different species within the Asteraceae

Discutindo a educação ambiental no cotidiano escolar: desenvolvimento de projetos na escola formação inicial e continuada de professores

A presente pesquisa buscou discutir como a Educação Ambiental (EA) vem sendo trabalhada, no Ensino Fundamental e como os docentes desta escola compreendem e vem inserindo a EA no cotidiano escolar., em uma escola estadual do município de Tangará da Serra/MT, Brasil. Para tanto, realizou-se entrevistas com os professores que fazem parte de um projeto interdisciplinar de EA na escola pesquisada. Verificou-se que o projeto da escola não vem conseguindo alcançar os objetivos propostos por: desconhecimento do mesmo, pelos professores; formação deficiente dos professores, não entendimento da EA como processo de ensino-aprendizagem, falta de recursos didáticos, planejamento inadequado das atividades. A partir dessa constatação, procurou-se debater a impossibilidade de tratar do tema fora do trabalho interdisciplinar, bem como, e principalmente, a importância de um estudo mais aprofundado de EA, vinculando teoria e prática, tanto na formação docente, como em projetos escolares, a fim de fugir do tradicional vínculo “EA e ecologia, lixo e horta”.Facultad de Humanidades y Ciencias de la Educació

Regulation and function of short stature homeobox (Shox) genes during development of the murine hindbrain

Disruption of putative enhancers downstream of the human short stature homeobox (SHOX) gene is thought to cause the limb defects characteristic of Léri–Weill dyschondrosteosis. Since the closely related mouse Shox2 gene has a similar function in limbs, we used a comparative approach to search for enhancer sequences responsible for driving limb expression of the Shox genes in mice and humans. Unexpectedly, transgenic analysis demonstrated that the most conserved enhancer sequences near the Shox genes were active in the central nervous system (CNS), suggesting an ancient function for these genes in this tissue. Given the results of the transgenic screens, and since Shox2 was shown to be expressed in the CNS, the major goal of this thesis became to explore the functional role of Shox2 in brain development and test the developmental and behavioural consequences of loss- and gain-of-function of Shox2 in mouse models. Using a conditional knockout strategy, we demonstrated that elimination of Shox2 in the brain results in developmental defects in the inferior colliculus and cerebellum. Specifically, loss of Shox2 in the cerebellum results in precocious differentiation and migration of granule cell precursors (GCPs). We showed that Shox2 is required for normal sonic hedgehog (Shh) expression in dorsal-residing Purkinje cells. In addition, the bone morphogenetic protein 4 (Bmp4) expression domain was expanded in Shox2-deficient animals, suggesting that Shox2 plays a key role in the proper interplay between cross-repressive SHH and BMP signalling. Moreover, loss of Shox2 causes behavioural abnormalities, including reduced exploratory activity, altered gait and impaired motor coordination. Furthermore, we demonstrated that elimination of Shox2 in the brain results in the loss of medially located visceral motor neurons (vMNs) in the facial motor nucleus. This correlates with impaired axonal projection properties of vMNs, which appears as improper branching and peripheral target acquisition of the facial (VII) nerves. Shox2-mutant neonates also displayed impaired feeding behaviour, likely due to improper development of the facial (VII) nerves. Together, these works have uncovered a novel function for Shox2 during hindbrain development. The Shox2-mutant model can now be exploited to further our understanding of neurogenesis, specification and circuit formation in the hindbrain

Ascl1 is required to specify a subset of ventromedial hypothalamic neurons

International audienceDespite clear physiological roles, the ventromedial hypothalamus (VMH) developmental programs are poorly understood. Here, we asked whether the proneural gene, Achaete-scute homolog1 (Ascl1), contributes to VMH development. Ascl1 transcripts were detected in E10.5-P0 VMH neural progenitors. The elimination of Ascl1 reduced the number of VMH neurons at E12.5 and E15.5, particularly within the VMH-central (VMHC) and -dorsomedial (VMHDM) subdomains and resulted in a VMH cell fate change from glutamatergic to GABAergic. We observed a loss of Neurog3 expression in Ascl1−/− hypothalamic progenitors and an upregulation of Neurog3 when Ascl1 was overexpressed. We also demonstrated a glutamatergic to GABAergic fate switch in Neurog3-null mutant mice, suggesting that Ascl1 might act via Neurog3 to drive VMH cell fate decisions. We also showed a concomitant increase in the central GABAergic fate determinant Dlx1/2 expression in the Ascl1-null hypothalamus. However, Ascl1 was not sufficient to induce an ectopic VMH fate when overexpressed outside of the normal window of competency. Combined, Ascl1 is required but not sufficient to specify the neurotransmitter identity of VMH neurons, acting in a transcriptional cascade with Neurog3

Born Digital Appraisal, Ingest, and Processing: Workshops and Tutorials - iPRES 2014 - Melbourne

This workshop is designed to gather together the community of digital archivists and others working specifically with born digital collections to discuss aspects of the appraisal, processing, and ingest process