Commitment in University Students: Generator of Successful Professionals

The University has historically been regarded as the harbinger of values, human rights, and other noble pursuits. It is within this atmosphere that personal development, mutual respect, and collaboration are expected to flourish through commitment to work and study. Yet in order for meaningful and sustainable social, economic, and political changes to take root, the author opines that certain adjustments to the overall social fabric are occasionally required and can only be achieved through unyielding commitment — an essential value transmitted from person to person through both individual and collective reflection

Limiting discounted-cost control of partially observable stochastic systems

This paper presents two main results on partially observable (PO) stochastic systems. In the first one, we consider a general PO system Xt+1 = F(xt, ~, ~J, Yt = G(xo 'IlJ (t = 0, 1, ... ) (*) on Borel spaces, with possibly unbounded cost-per-stage functions, and give conditions for the existence of a-discount optimal control policies (0 < a < 1). In the second result we specialize (*) to additive-noise systems xt+1 = Fo (Xt' aJ + ~o Yt = Go (xJ + 'Ilt (t= 0, 1, ... ) in Euclidean spaces, with Fn (x,a) and Go(x) converging pointwise to functions F «l(x, a) and G«l(x), respectively, and give conditions for the limiting PO model Xt+1 = F «l(xt, aJ + ~t Yt = G«l(xJ + 'Ilt to have an a-discount optimal policy

Matrilineal Heritage in Southern Iberia Reveals Deep Genetic Links between Continents

Within the Mediterranean Basin, the Iberian Peninsula has been a focus of attraction for several cultures and civilizations from its prehistory and history, making it a target territory for studying human migration patterns and peopling processes using a wide and heterogeneous spectrum of genomic markers. While its Cantabrian fringe represents the most regularly analysed area in terms of its mitochondrial diversity, the absence of monographic surveys on the maternal genetic composition of southern Iberians (i.e., Andalusians) is striking. In this work, we present a comprehensive view of various aspects of the human maternal heritage of the autochthonous Andalusian population regarding specific mitochondrial haplogroups considered key candidates to determine the genetic relationship between Europe and Africa. Data reveal that southern Iberian populations do not have genetically homogeneous mitochondrial DNA profiles, and their observed genetic affinity with north-western African populations represents strong signals of old, sustained and bidirectional human movements between the northern and southern shores of the western Mediterranean. Thorough analyses of African mtDNA haplogroups have shown that the most relevant African contribution within Iberian Peninsula could be explained as a consequence of prehistoric events. The subsequent historic episodes helped to strengthen the ties between both shores. In southern Iberia, mitochondrial and other genetic markers show that the Strait of Gibraltar together with its surrounding maritime areas should be considered a bridge between continents. More broadly, the Mediterranean Sea has acted as a transport surface, that is, as a permeable barrier to human migrations from prehistoric and historic times. In conclusion, this research contributes to our knowledge of processes that have shaped the recent human genetic history in the Mediterranean and, more specifically, of the population dynamics that the inhabitants of southern Iberia have experienced with respect to other neighbouring North African populations

Commitment in University Students: Generator of Successful Professionals

The University has historically been regarded as the harbinger of values, human rights, and other noble pursuits. It is within this atmosphere that personal development, mutual respect, and collaboration are expected to flourish through commitment to work and study. Yet in order for meaningful and sustainable social, economic, and political changes to take root, the author opines that certain adjustments to the overall social fabric are occasionally required and can only be achieved through unyielding commitment — an essential value transmitted from person to person through both individual and collective reflection

Asymmetric preparation of antifungal 1-(4 -chlorophenyl)-1-cyclopropyl methanol and 1-(4 -chlorophenyl)-2-phenylethanol. Study of the detoxification mechanism by Botrytis cinerea

Chiral alcohols are important as bioactive compounds or as precursors to such molecules. On the basis of the different antifungal properties of the enantiopure alcohol derivatives of 4-chlorophenyl cyclopropyl ketone and benzyl 4-chlorophenyl ketone, their enantioselective synthesis by chemical and biocatalytic methods was studied. The detoxification pathways by the phytopathogen fungus Botrytis cinerea are reported

Botrylactone: new interest in an old moleculedreview of its absolute configuration and related compounds

The absolute configuration of botrylactone, a unique compound with an interesting polyketide lactone skeleton with two oxirane bridges previously isolated from Botrytis cinerea and described as a powerful antibiotic, has been reviewed on the basis of sign of the optical rotation, NOE experiments and NMR method. The isolation of 7-deoxybotrylactone and 5-hydroxy-7-(4-hydroxydec-2(3)-enoyl) botrylactone enables us to characterize an intriguing new family of compounds with this interesting polyketide skeleton. A common biosynthetic origin with botcinin derivatives is proposed

“Report on the good news!” a didactic proposal to promote communication and cooperation in english as a second language

Este trabajo incluye la propuesta y la evaluación crítica de una unidad didáctica innovadora que busca el promover la comunicación y la cooperación en un grupo de cuarto de la ESO. La unidad está basada en bastantes de los principios de enfoques metodológicos tales como el aprendizaje basado en proyectos o la enseñanza basada en tareas, así como otros enfoques teóricos fundamentales como la enseñanza de la lengua basada en la comunicación y el aprendizaje cooperativo. Estos se apoyan en el uso de herramientas digitales como las TICs y las TACs y su relación con el currículo aragonés para la educación secundaria. Además, la unidad didáctica incluida en este trabajo es un proyecto compuesto por siete lecciones centradas en la creación de un producto final, un episodio de un podcast que gira alrededor varios avances innovativos, incluyendo áreas como la tecnología y la medicina. La propuesta cubre el “reported speech” basado en tareas que se benefician de numerosas herramientas de evaluación y apoyo que respaldan la coevaluación de las habilidades, así como el fomento de inteligencias múltiples.<br /

Hydrazones as Singular Reagents in Asymmetric Organocatalysis

This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions. The key structural elements governing the reactivity of these reagents in a preferred pathway will be discussed, as well as their different interactions with organocatalysts, leading to diverse activation modes. Along these studies, the synthetic equivalence of N-monoalkyl, N,N-dialkyl, and N-acyl hydrazones with several synthons is also highlighted. Emphasis is also put on the mechanistic studies performed to understand the observed reactivities. Finally, the functional group transformations performed from the available products has also been analyzed, highlighting the synthetic value of these methodologies, which served to access numerous families of valuable multifunctional compounds and nitrogen-containing heterocycles.Ministerio de Economía y Competitividad CTQ2013-48164-C2-1-P, CTQ201348164-C2-2-PEuropean FEDER fundsJunta de Andalucía 2012/FQM 107

Características geológicas y metalogénicas de la mineralización de Cu-Zn-Pb-Ag de Congostrina, Sistema Central.

Las investigaciones realizadas en la zona de Congostrina han consistido en la descripción de las características morfológicas de la mineralización y su encuadre dentro del contexto de la metalogenia de la plata del Sistema Central. Asimismo se han estudiado los aspectos mineralógicos y texturales de los principales minerales de plata, estableciéndose la paragénesis y sucesión mineral del yacimiento