The absolute configuration of botrylactone, a unique compound with an interesting polyketide lactone
skeleton with two oxirane bridges previously isolated from Botrytis cinerea and described as a powerful
antibiotic, has been reviewed on the basis of sign of the optical rotation, NOE experiments and NMR
method. The isolation of 7-deoxybotrylactone and 5-hydroxy-7-(4-hydroxydec-2(3)-enoyl) botrylactone
enables us to characterize an intriguing new family of compounds with this interesting polyketide
skeleton. A common biosynthetic origin with botcinin derivatives is proposed