Space, mass and ornament in the Gothic-Renaissance transition in Spain

La introducción en España de las nuevas formas y sintaxis renacentistas a lo largo del siglo xvi no se produjo con un abandono radical e inmediato de los viejos usos góticos, de validez comprobada en trascendentales cuestiones del diseño arquitectónico. La renovación de la producción fue heterogénea y en cierto modo particular de cada artífice, según su formación previa y el grado de contacto, coherencia y compromiso con las novedades italianas, generando un panorama híbrido y plural en la arquitectura del quinientos hispano. Atendiendo a significativos textos y documentos gráficos de la época, se pretende rastrear los cambios, e inercias, en el proceso de diseño arquitectónico durante esta larga etapa de transición, estructurando el análisis a partir de tres categorías sustanciales, interdependientes y autónomas a la vez: espacio, masa y ornato.During the sixteenth century the new Renaissance forms were introduced in Spain, but the Gothic procedures continued to be used due to their proven validity for the architectural design. The renovation of the architecture was heterogeneous and different for each master, according to his previous training and his knowledge of the new Italian forms. This involved a hybrid and plural context in the Spanish architecture of the 16th century. The changes and continuities of the architectural design process during this transitory stage are investigated in this paper, based on significant texts and graphic documents of this period. The analysis is structured based on three substantial architectural categories, which are simultaneously interdependent and autonomous: space, mass and ornamen

The importance of early parenting for later child outcomes: A study with Spanish families with children with disabilities

Children with different disability conditions have varied developmental trajectories, which perhaps influences parent-child interaction. For these and all infants, an optimal home environment that includes good parenting and positive parent-child interactions predicts better developmental outcomes (Spiker et al., 2005). Interventions using a family-centered, parenting-focused approach result in better parenting behavior that contributes to improved early child development (Avellar & Suplee, 2013; Roggman & Cardia, 2016). Information on parent-child interaction patterns is needed to guide intervention in natural contexts of families (Fuligni & Brooks-Gunn, 2013). Parent-child interaction data were collected from 44 mothers and 35 fathers interacting with their children (23 to 47 months) who had a disability and were in one of eight Spanish Early Interventions Centers. Mothers and fathers, separately, auto-recorded 10-minute play sessions at home. Parental interactions were assessed using PICCOLO (Roggman et al., 2013), a standardized measure of parenting. Two independent observers coded the interactions; strong intra-class correlation coefficients were found (.82 to .97 for mothers, .77 to .89 for fathers). The BSID-III scales (Bayley, 2015) assessed children’s development. Mothers scored slightly higher than did fathers. Scores varied by PICCOLO domains but were consistent with other PICCOLO studies of typical developing children (Roggman et al., 2013). Mother and father’s scores correlated indicating that the higher the scores of mothers in any dimension correlated with those of the parents combined. Positive significant Pearson correlations were found between parenting and child’s development with different patterns of father and mother domains predicting better language and cognitive outcomes. Although barriers to optimal parenting need further investigation, PICCOLO can be a useful tool to support optimal parenting.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Asimetría fluctuante como un indicador de estrés ambiental en pequeños mamíferos

La estabilidad del desarrollo de un organismo se refleja en la capacidad que posee de producir una forma “ideal” bajo un conjunto particular de condiciones. Las estructuras bilaterales en organismos con simetría bilateral ofrecen una simetría precisa sobre la cual se pueden comparar desviaciones. La herramienta más utilizada para estimar la estabilidad del desarrollo es la asimetría fluctuante, la cual considera las pequeñas desviaciones aleatorias que ocurren entre los lados derecho e izquierdo de rasgos bilaterales, y es la única asimetría adecuada como indicador de estrés ambiental/genético. Resumimos cuatro décadas de estudios en donde la asimetría fluctuante fue utilizada para evaluar el efecto de estrés ambiental sobre pequeños mamíferos. Este grupo de especies ha sido ampliamente utilizado en estudios ecológicos para inferir perturbaciones ambientales debido a sus variadas características. Se seleccionaron 27 artículos compilados con Google Académico, utilizando “asimetría fluctuante” y “pequeños mamíferos” como palabras claves, escritas en inglés y con objetivos ecológicos. Centramos nuestro análisis en los enfoques utilizados para evaluar la asimetría fluctuante (medidas lineales o morfometría geométrica), el factor de estrés (natural o antropogénico), la región donde se desarrolló el estudio, el número de rasgos utilizado en los estudios y las fuentes de datos (muestras de pellets de lechuza, colecciones científicas y capturas directa de animales). La revisión muestra la importancia de incluir la asimetría fluctuante en estudios ecológicos como un indicador biológico confiable, económico y rápido del efecto del estrés ambiental sobre los mamíferos.The developmental stability of an organism is reflected in its ability to produce an ‘ideal’ form under a particular set of conditions. Bilateral structures in bilaterally symmetrical organisms offer a precise symmetry against which departures may be compared. The tool mostly used to estimate the development stability is fluctuating asymmetry, which considers small random deviations that occur between the left and right sides of a bilateral trait. Fluctuating asymmetry is considered as the only form of asymmetry that can serve as a useful indicator of environmental/genetic stress. We summarized four decades of studies where fluctuating asymmetry was used to assess the effects of environmental stress in small mammals. This group of species has been widely used in ecological studies to infer environmental disturbances because of its wide range of characteristics. We selected 27 articles that were compiled with Google Scholar (Mountain View, CA) using “fluctuating asymmetry” and “small mammals” as key words, written in English and with ecological objectives. We focused our analyses on the approaches used to evaluate fluctuating asymmetry (linear measurements or geometric morphometrics), the stress factor (natural or anthropogenic), the region where the study was developed, the number of traits used in the studies and the data sources, including measures obtained from samples of barn owl pellets, scientific collections and captured animals. The review shows the importance of including fluctuating asymmetry in ecological studies as a reliable, cheap and fast biological indicator of the effect of environmental stress on mammals.Fil: Coda, José Antonio. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Ciencias Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Martínez, Juan José. Universidad Nacional de Jujuy. Instituto de Ecorregiones Andinas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Ecorregiones Andinas; ArgentinaFil: Steinmann, Andrea Rosa. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Ciencias Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Priotto, Jose Waldemar. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Ciencias Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gomez, Maria Daniela. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Ciencias Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

First report of Desmiphora hirticollis (Olivier) (Coleoptera: Cerambycidae) on Wigandia urens (Ruiz and Pavón) H.B.K. (Hydrophilaceae) in Mexico

Desmiphora hirticollis (Olivier) (Coleoptera: Cerambycidae) was found in Oaxaca, Mexico, feeding in the stems of Wigandia urens (Ruiz and Pavón) H.B.K. (Hydrophilaceae), a new host record. Information about damage in the plant stems and some observations of the insect’s biology are provided

Pesquisa de agentes entomopatogénicos na ilha do Pico (Açores)

XII Expedição Científica do Departamento de Biologia - Pico 2005.Durante a “Expedição Científica Pico 2005” efectuou-se a recolha de amostras de solo para pesquisar nemátodes entomopatogénicos. Com o designado “Galleria trap method” e pela técnica de flutuação-centrifugação re-isolou-se um nemátode do género Steinernema. Esse nemátode, Steinernema carpocapse, isolado Az27 foi pela primeira vez isolado na ilha do Pico no ano de 1991.ABSTRACT: A survey for entomopathogens in soil samples was carried during the “Scientific Expedition Pico 2005” as a part of a project of survey and characterization of insect parasites in the Azores. One steinernematid was re-isolated with the “Galleria trap method” and flotation centrifugation techniques

TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells

The epithelial-to-mesenchymal transition (EMT) and its reversion (MET) are related to tumor cell dissemination and migration, tumor circulating cell generation, cancer stem cells, chemoresistance, and metastasis formation. To identify chromatin and epigenetic factors possibly involved in the process of EMT, we compare the levels of expression of epigenetic genes in a transformed human breast epithelial cell line (HMEC-RAS) versus a stable clone of the same cell line expressing the EMT master regulator ZEB1 (HMEC-RAS-ZEB1). One of the factors strongly induced in the HMEC-RAS-ZEB1 cells was Transducin beta-like 1 (TBL1), a component of the NCoR complex, which has both corepressor and coactivator activities. We show that TBL1 interacts with ZEB1 and that both factors cooperate to repress the promoter of the epithelial gene E-cadherin (CDH1) and to autoactivate the ZEB1 promoter. Consistent with its central role, TBL1 is required for mesenchymal phenotypes of transformed breast epithelial and breast cancer cell lines of the claudin-low subtype. Importantly, a high expression of the TBL1 gene correlates with poor prognosis and increased proportion of metastasis in breast cancer patients, indicating that the level of TBL1 expression can be used as a prognostic marker.Ministerio de Economía y Competitividad BFU2014-53543-P, BFU2017-85420-RJunta de Andalucía BIO-32

Reduced heart rate variability predicts fatigue severity in individuals with chronic fatigue syndrome/myalgic encephalomyelitis

Heart rate variability (HRV) is an objective, non-invasive tool to assessing autonomic dysfunction in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). People with CFS/ME tend to have lower HRV; however, in the literature there are only a few previous studies (most of them inconclusive) on their association with illness-related complaints. To address this issue, we assessed the value of different diurnal HRV parameters as potential biomarker in CFS/ME and also investigated the relationship between these HRV indices and self-reported symptoms in individuals with CFS/ME.Peer ReviewedPostprint (published version

Cosmological solutions in generalized hybrid metric-Palatini gravity

We construct exact solutions representing a Friedmann-Lema\^itre-Robsertson-Walker (FLRW) universe in a generalized hybrid metric-Palatini theory. By writing the gravitational action in a scalar-tensor representation, the new solutions are obtained by either making an ansatz on the scale factor or on the effective potential. Among other relevant results, we show that it is possible to obtain exponentially expanding solutions for flat universes even when the cosmology is not purely vacuum. We then derive the classes of actions for the original theory which generate these solutions.Comment: 14 pages, 17 figure

ASSESSING ADMINISTRATION CHARGES FOR THE AFFILIATE IN INDIVIDUAL ACCOUNT SYSTEMS

In any pension system based on capitalization, affiliates have to cover certain explicit costs which in a pay-as-you-go system would be implicit. In this paper we set out a model based on Whitehouse (2000) and Diamond (1999) to enable the explicit costs borne by the affiliate both during his working life and his retirement period to be assessed. It also shows the relationships between the different ways of measuring the costs that make up the total price finally paid by the contributors. Included in the model is the notable effect that some factors -such as gaps in contribution profiles, account transfers and changes in salary profiles- have on projecting the costs borne by the affiliates. Finally we carry out an international comparison of administration costs from the point of view of the affiliate, focusing special attention on the countries of Latin America and Spain. This has a double objective: 1.- To test the validity of criticisms made by some researchers as to whether the new capitalization systems introduced in Latin America are too expensive to run for the affiliates. 2.- To serve as a reference for the individual pension scheme system in Spain. En un sistema de pensiones basado en la capitalización los afiliados deben hacer frentea unos costes explícitos que en el sistema de reparto son implícitos. En este trabajo sedesarrolla un modelo, basado en Whitehouse (2000) y Diamond (1999), que permite evaluarlas comisiones explícitas que soporta el afiliado, tanto durante la vida laboral como durante laetapa de jubilación y que, además, muestra la relación entre las diferentes medidas de loscostes que integran el precio total que finalmente pagan los cotizantes. En el modelo seintroduce el efecto de algunos aspectos que tienen una repercusión muy importante en laproyección de los costes que soportan los afiliados: ¿vacíos¿ en los perfiles de aportación,efecto de los traspasos de fondos y cambio en los perfiles de salarios. Por último, se realizauna comparación internacional de los costes de administración desde la óptica de los afiliadoscon un doble objetivo:1.-Contrastar la validez de la crítica realizada por algunos investigadores a los nuevossistemas de capitalización individual implantados en América Latina, en el sentido de que sonexcesivamente caros de gestionar para los afiliados.2.-Servir de referencia para el sistema de planes de pensiones individuales en España.Capitalización, Costes de Administración, Fondo de pensiones, América Latina. Capitalization, Administration Costs, Pension Funds, Latin America