The lambda-dimension of commutative arithmetic rings

It is shown that every commutative arithmetic ring $R$ has $lambda$-dimension $leq 3$. An example of a commutative Kaplansky ring with $lambda$-dimension 3 is given. If $R$ satisfies an additional condition then $lambda$-dim($R$

Automated surveillance and detection of foreign stationary objects

Abstract: CCTV systems are frequently monitored manually by a human observer. This human observer is typically responsible for dealing with tens or hundreds of cameras at a time. Potential security threats may easily be missed by the system’s human operators due to fatigue or being overwhelmed by the amount of change in the images..

Stationary region predictor using a stationary camera

A method to determine the stationery probability of regions or feature points in a video sequence is proposed in this paper. This is done by identifying feature points using the Harris corner detector, finding descriptors for the feature points and then tracking the feature points. The information gained from tracking the feature points is then used to determine the stationery probability of these features. This method is shown to successfully identify probable stationery and moving regions in video sequences

Resultaten en ambities : proef de vooruitgang!

In 2007 namen Ziekenhuis Gelderse Vallei in Ede en de afdeling Humane Voeding van Wageningen University het initiatief tot samenwerking en vormden zij de Alliantie Voeding Gelderse Vallei. De Alliantie Voeding koppelt preventie aan zorg. Voor jong tot oud is voorlichting over gezonde voeding van belang. Effectieve preventie én de integratie van preventie in de zorg levert gezondheidswinst en verhoging van kwaliteit van leven op individueel en populatie niveau. De Alliantie Voeding heeft hiertoe drie programma's opgesteld

Climate Education Course Proposal for School of Sustainability

Seeking to address the lack of eco-literacy, we developed a syllabus for a course at Loyola University Chicago with the intended purpose of instilling climate knowledge to others. Through our own experiences studying environmental sustainability, we shared the same issue of lacking inadequate communication skills about climate change for different audiences. To develop the course structure and content, we gathered knowledge from community experts in environmental education and researched what other schools have implemented in the environmental education field. Our product is a syllabus, learning outcomes, and rationale for a new course devoted to teaching Loyola undergraduates how to educate others about climate change in ways that enable people to help avert the climate crisis

Exploring preferences for domain-specific goal management in patients with polyarthritis: what to do when an important goal becomes threatened?

Usually priorities in goal management—intended to minimize discrepancies between a given and desired situation—are studied as person characteristics, neglecting possible domain-specific aspects. However, people may make different decisions in different situations depending on the importance of the personal issues at stake. Aim of the present study therefore was to develop arthritis-related vignettes to examine domain-specific goal management and to explore patients’ preferences. Based on interviews and literature, situation-specific hypothetical stories were developed in which the main character encounters a problem with a valued goal due to arthritis. Thirty-one patients (61 % female, mean age 60 years) evaluated the face validity of the newly developed vignettes. Secondly, 262 patients (60 % female, mean age 63 years) were asked to come up with possible solutions for the problems with attaining a goal described in a subset of the vignettes. Goal management strategies within the responses and the preference for the various strategies were identified. The 11 developed vignettes in three domains were found to be face-valid. In 90 % of the responses, goal management strategies were identified (31 % goal maintenance, 29 % goal adjustment, 21 % goal disengagement, and 10 % goal re-engagement). Strategy preference was related to domains. Solutions containing goal disengagement were the least preferred. Using vignettes for measuring domain-specific goal management appears as valuable addition to the existing questionnaires. The vignettes can be used to study how patients with arthritis cope with threatened goals in specific domains from a patient’s perspective. Domain-specific strategy preference emphasizes the importance of a situation-specific instrument

Asthmatic lung fibroblasts promote type 2 immune responses via endoplasmic reticulum stress response dependent thymic stromal lymphopoietin secretion

Lung fibroblasts contribute to asthma pathology partly through modulation of the immune environment in the airway. Tumor necrosis factor-α (TNFα) expression is upregulated in asthmatic lungs. How asthmatic lung fibroblasts respond to TNFα stimulation and subsequently regulate immune responses is not well understood. Endoplasmic reticulum (ER) stress and unfolded protein responses (UPR) play important roles in asthma, but their functional roles are still under investigation. In this study, we investigated TNFα-induced cytokine production in primary lung fibroblasts from asthmatic vs. non-asthmatic human subjects, and downstream effects on type 2 immune responses. TNFα significantly upregulated IL-6, IL-8, C-C motif chemokine ligand 5 (CCL5), and thymic stromal lymphopoietin (TSLP) mRNA expression and protein secretion by lung fibroblasts. Asthmatic lung fibroblasts secreted higher levels of TSLP which promoted IL-33-induced IL-5 and IL-13 production by peripheral blood mononuclear cells. TNFα exposure enhanced expression of ER stress/UPR pathways in both asthmatic and non-asthmatic lung fibroblasts, especially inositol-requiring protein 1α in asthmatics. ER stress/UPR inhibitors decreased IL-6, CCL5, and TSLP protein secretion by asthmatic lung fibroblasts. Our data suggest that TNFα and lung fibroblasts form an important axis in asthmatic lungs to promote asthmatic inflammation that can be attenuated by inhibiting ER stress/UPR pathway.</p

Asthmatic lung fibroblasts promote type 2 immune responses via endoplasmic reticulum stress response dependent thymic stromal lymphopoietin secretion

Lung fibroblasts contribute to asthma pathology partly through modulation of the immune environment in the airway. Tumor necrosis factor-α (TNFα) expression is upregulated in asthmatic lungs. How asthmatic lung fibroblasts respond to TNFα stimulation and subsequently regulate immune responses is not well understood. Endoplasmic reticulum (ER) stress and unfolded protein responses (UPR) play important roles in asthma, but their functional roles are still under investigation. In this study, we investigated TNFα-induced cytokine production in primary lung fibroblasts from asthmatic vs. non-asthmatic human subjects, and downstream effects on type 2 immune responses. TNFα significantly upregulated IL-6, IL-8, C-C motif chemokine ligand 5 (CCL5), and thymic stromal lymphopoietin (TSLP) mRNA expression and protein secretion by lung fibroblasts. Asthmatic lung fibroblasts secreted higher levels of TSLP which promoted IL-33-induced IL-5 and IL-13 production by peripheral blood mononuclear cells. TNFα exposure enhanced expression of ER stress/UPR pathways in both asthmatic and non-asthmatic lung fibroblasts, especially inositol-requiring protein 1α in asthmatics. ER stress/UPR inhibitors decreased IL-6, CCL5, and TSLP protein secretion by asthmatic lung fibroblasts. Our data suggest that TNFα and lung fibroblasts form an important axis in asthmatic lungs to promote asthmatic inflammation that can be attenuated by inhibiting ER stress/UPR pathway.</p