289 research outputs found
Sensitive VLBI Continuum and H I Absorption Observations of NGC 7674: First Scientific Observations with the Combined Array VLBA, VLA & Arecibo
We present phase-referenced VLBI observations of the radio continuum emission
from, and the H I 21 cm absorption toward, the Luminous Infrared Galaxy NGC
7674. The observations were carried out at 1380 MHz using the VLBA, the phased
VLA, and theArecibo radio telescope. These observations constitute the first
scientific use of the Arecibo telescope in a VLBI observation with the VLBA.
The high- and low-resolution radio continuum images reveal several new
continuum structures in the nuclear region of this galaxy. At ~100 mas
resolution, we distinguish six continuum structures extending over 1.4 arcsec,
with a total flux density of 138 mJy. Only three of these structures were known
previously. All these structures seem to be related to AGN activity. At the
full resolution of the array, we only detect two of the six continuum
structures. Both are composed of several compact components with brightness
temperatures on the order of K. While it is possible that one of these
compact structures could host an AGN, they could also be shock-like features
formed by the interaction of the jet with compact interstellar clouds in the
nuclear region of this galaxy. Complex H I absorption is detected with our VLBI
array at both high and low angular resolution. Assuming that the widest H I
feature is associated with a rotating H I disk or torus feeding a central AGN,
we estimate an enclosed dynamical mass of ~7 x 10^7 M_sun, comparable to the
value derived from the hidden broad H emission in this galaxy. The
narrower H I lines could represent clumpy neutral hydrogen structures in the H
I torus. The detection of H I absorption toward some of the continuum
components, and its absence toward others, suggest an inclined H I disk or
torus in the central region of NGC 7674.Comment: 37 pages, 11 figures. ApJ accepted. To appear in the Nov. 10, 2003
issue of ApJ. Please use the PDF version if the postscript doesn't show the
figure
Come to Daddy? Claiming Chris Cunningham for British Art Cinema
Twenty years after he came to prominence via a series of provocative, ground-breaking music videos, Chris Cunningham remains a troubling, elusive figure within British visual culture. His output – which includes short films, advertisements, art gallery commissions, installations, music production and a touring multi-screen live performance – is relatively slim, and his seemingly slow work rate (and tendency to leave projects uncompleted or unreleased) has been a frustration for fans and commentators, particularly those who hoped he would channel his interests and talents into a full-length ‘feature’ film project. There has been a diverse critical response to his musical sensitivity, his associations with UK electronica culture – and the Warp label in particular – his working relationship with Aphex Twin, his importance within the history of the pop video and his deployment of transgressive, suggestive imagery involving mutated, traumatised or robotic bodies. However, this article makes a claim for placing Cunningham within discourses of British art cinema. It proposes that the many contradictions that define and animate Cunningham's work – narrative versus abstraction, political engagement versus surrealism, sincerity versus provocation, commerce versus experimentation, art versus craft, a ‘British’ sensibility versus a transnational one – are also those that typify a particular terrain of British film culture that falls awkwardly between populism and experimentalism
A comparative HST imaging study of the host galaxies of radio-quiet quasars, radio-loud quasars and radio galaxies: Paper I
We present the first results from a major HST WFPC2 imaging study aimed at
providing the first statistically meaningful comparison of the morphologies,
luminosities, scalelengths and colours of the host galaxies of radio-quiet
quasars, radio-loud quasars, and radio galaxies. We describe the design of this
study and present the images which have been obtained for the first half of our
33-source sample. We find that the hosts of all three classes of luminous AGN
are massive elliptical galaxies, with scalelengths ~=10 kpc, and R-K colours
consistent with mature stellar populations. Most importantly this is the the
first unambiguous evidence that, just like radio-loud quasars, essentially all
radio-quiet quasars brighter than M_R = -24 reside in massive ellipticals. This
result removes the possibility that radio `loudness' is directly linked to host
galaxy morphology, but is however in excellent accord with the
black-hole/spheroid mass correlation recently highlighted by Magorrian et al.
(1998). We apply the relations given by Magorrian et al. to infer the expected
Eddington luminosity of the putative black hole at the centre of each of the
spheroidal host galaxies we have uncovered. Comparison with the actual nuclear
R-band luminosities suggests that the black holes in most of these galaxies are
radiating at a few percent of the Eddington luminosity; the brightest host
galaxies in our low-z sample are capable of hosting quasars with M_R = -28,
comparable to the most luminous quasars at z = 3. Finally we discuss our
host-derived black-hole masses in the context of the
radio-luminosity:black-hole mass correlation recently uncovered for nearby
galaxies by Franceschini et al. (1998), and the resulting implications for the
physical origin of radio loudness.Comment: Submitted for publication in the Astrophysical Journal, 55 pages of
latex, plus 12 postscript figures (Figures 1a-1s (greyscales of images and
model fits, and Figures 2a-2g (luminosity profiles and model fits) can be
downloaded from http://www.roe.ac.uk/astronomy/html/rjm1.shtml
Potential conservation of circadian clock proteins in the phylum Nematoda as revealed by bioinformatic searches
Although several circadian rhythms have been described in C. elegans, its molecular clock remains elusive. In this work we employed a novel bioinformatic approach, applying probabilistic methodologies, to search for circadian clock proteins of several of the best studied circadian model organisms of different taxa (Mus musculus, Drosophila melanogaster, Neurospora crassa, Arabidopsis thaliana and Synechoccocus elongatus) in the proteomes of C. elegans and other members of the phylum Nematoda. With this approach we found that the Nematoda contain proteins most related to the core and accessory proteins of the insect and mammalian clocks, which provide new insights into the nematode clock and the evolution of the circadian system.Fil: Romanowski, Andrés. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones BioquÃmicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones BioquÃmicas de Buenos Aires; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y TecnologÃa. Laboratorio de CronobiologÃa; ArgentinaFil: Garavaglia, MatÃas Javier. Universidad Nacional de Quilmes. Departamento de Ciencia y TecnologÃa. Laboratorio de Ing.genética y Biolog.molecular y Celular. Area Virus de Insectos; Argentina. Consejo Nacional de Investigaciones CientÃficas y Técnicas; ArgentinaFil: Goya, MarÃa Eugenia. Universidad Nacional de Quilmes. Departamento de Ciencia y TecnologÃa. Laboratorio de CronobiologÃa; Argentina. Consejo Nacional de Investigaciones CientÃficas y Técnicas; ArgentinaFil: Ghiringhelli, Pablo Daniel. Universidad Nacional de Quilmes. Departamento de Ciencia y TecnologÃa. Laboratorio de Ing.genética y Biolog.molecular y Celular. Area Virus de Insectos; Argentina. Consejo Nacional de Investigaciones CientÃficas y Técnicas; ArgentinaFil: Golombek, Diego Andres. Universidad Nacional de Quilmes. Departamento de Ciencia y TecnologÃa. Laboratorio de CronobiologÃa; Argentina. Consejo Nacional de Investigaciones CientÃficas y Técnicas; Argentin
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Consultation on revised behaviour in schools guidance and suspension and permanent exclusion guidance: response from the British Psychological Society
This paper sets out the British Psychological Society’s (BPS) submission to the Department for Education’s consultation on Revised Behaviour in Schools Guidance and Suspension and Permanent Exclusion Guidance. The BPS is the representative body for psychology and psychologists in the UK, and is responsible for the promotion of excellence and ethical practice in the science, education, and application of the discipline
HPV infection and number of lifetime sexual partners are strong predictors for ‘natural’ regression of CIN 2 and 3
The aim of this paper was to evaluate the factors that predict regression of untreated CIN 2 and 3. A total of 93 patients with colposcopic persistent CIN 2 and 3 lesions after biopsy were followed for 6 months. Human papillomavirus (HPV) types were determined by polymerase chain reaction at enrolment. We analysed the biologic and demographic predictors of natural regression using univariate and multivariate methods. The overall regression rate was 52% (48 out of 93), including 58% (22 out of 38) of CIN 2 and 47% (26 out of 55) of CIN 3 lesions (P=0.31 for difference). Human papillomavirus was detected in 84% (78 out of 93) of patients. In univariate analysis, 80% (12 out of 15) of lesions without HPV regressed compared to 46% (36 out of 78) of lesions with HPV infection (P=0.016). Women without HPV and those who had a resolution of HPV had a four-fold higher chance of regression than those with persistent HPV (relative odds=3.5, 95% CI=1.4-8.6). Women with five or fewer lifetime sexual partners had higher rates of regression than women with more than five partners (P=0.003). In multivariate analysis, HPV status and number of sexual partners remained as significant independent predictors of regression. In conclusion, HPV status and number of lifetime sexual partners were strongly predictive of regression of untreated CIN 2 and 3
Multi-dimensionality and variability in folk classification of stingless bees (Apidae: Meliponini)
Background: Not long ago Eugene Hunn suggested using a combination of cognitive, linguistic, ecological and evolutionary theories in order to account for the dynamic character of ethnoecology in the study of folk classification systems. In this way he intended to question certain homogeneity in folk classifications models and deepen in the analysis and interpretation of variability in folk classifications. This paper studies how a rural culturally mixed population of the Atlantic Forest of Misiones (Argentina) classified honey-producing stingless bees according to the linguistic, cognitive and ecological dimensions of folk classification. We also analyze the socio-ecological meaning of binomialization in naming and the meaning of general local variability in the appointment of stingless bees. Methods: We used three different approaches: the classical approach developed by Brent Berlin which relies heavily on linguistic criteria, the approach developed by Eleonor Rosch which relies on psychological (cognitive) principles of categorization and finally we have captured the ecological dimension of folk classification in local narratives. For the second approximation, we developed ways of measuring the degree of prototypicality based on a total of 107 comparisons of the type "X is similar to Y" identified in personal narratives. Results: Various logical and grouping strategies coexist and were identified as: graded of lateral linkage, hierarchical and functional. Similarity judgments among folk taxa resulted in an implicit logic of classification graded according to taxa's prototypicality. While there is a high agreement on naming stingless bees with monomial names, a considerable number of underrepresented binomial names and lack of names were observed. Two possible explanations about reported local naming variability are presented. Conclusions: We support the multidimensionality of folk classification systems. This confirms the specificity of local classification systems but also reflects the use of grouping strategies and mechanisms commonly observed in other cultural groups, such as the use of similarity judgments between more or less prototypical organisms. Also we support the idea that alternative naming results from a process of fragmentation of knowledge or incomplete transmission of knowledge. These processes lean on the facts that culturally based knowledge, on the one hand, and biologic knowledge of nature on the other, can be acquired through different learning pathways.Fil: Zamudio, Fernando. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Córdoba. Instituto Multidisciplinario de BiologÃa Vegetal (p); ArgentinaFil: Hilgert, Norma Ines. Consejo Nacional de Investigaciones CientiâÂficas y Tecnicas. Centro Cientifico Tecnologico Nordeste. Instituto de Biologia Subtropical. Instituto de Biologia Subtropical - Nodo Puerto Iguazu; Argentin
Lipopolysaccharide Renders Transgenic Mice Expressing Human Serum Amyloid P Component Sensitive to Shiga Toxin 2
Transgenic C57BL/6 mice expressing human serum amyloid P component (HuSAP) are resistant to Shiga toxin 2 (Stx2) at dosages that are lethal in HuSAP-negative wild-type mice. However, it is well established that Stx2 initiates extra-intestinal complications such as the haemolytic-uremic syndrome despite the presence of HuSAP in human sera. We now demonstrate that co-administering purified Escherichia coli O55 lipopolysaccharide (LPS), at a dosage of 300 ng/g body weight, to HuSAP-transgenic mice increases their susceptibility to the lethal effects of Stx2. The enhanced susceptibility to Stx2 correlated with an increased expression of genes encoding the pro-inflammatory cytokine TNFα and chemokines of the CXC and CC families in the kidneys of LPS-treated mice, 48 hours after the Stx2/LPS challenge. Co-administering the glucocorticoid dexamethasone, but not the LPS neutralizing cationic peptide LL-37, protected LPS-sensitized HuSAP-transgenic mice from lethal doses of Stx2. Dexamethasone protection was specifically associated with decreased expression of the same inflammatory mediators (CXC and CC-type chemokines and TNFα) linked to enhanced susceptibility caused by LPS. The studies reveal further details about the complex cascade of host-related events that are initiated by Stx2 as well as establish a new animal model system in which to investigate strategies for diminishing serious Stx2-mediated complications in humans infected with enterohemorrhagic E. coli strains
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