Compact forms of reduced density matrices

10 págs.; 3 tabs.; PACS number~s!: 31.15.Hz, 31.10.1zThe necessary and sufficient minimum information carried by reduced density matrices (RDM) are discussed. A method is reported for obtaining the same information as a p-RDM although in compact form, from which all the redundant information is omitted. The algebra operations and basic properties of these compact-form matrices are obtained. ©2003 The American Physical SocietyWe are greatly indebted to the Spanish Ministerio de Educación, Cultura y Deporte for its support under Project No. BQU2000-1158Peer Reviewe

Síntesis y aplicación de los ortofosfatos de magnesio en procesos orgánicos

La memoria, se enmarca dentro de un amplio plan de investigación, que se viene desarrollando en el Dpto. de Química Orgánica de la Universidad de Córdoba, sobre empleo de ortofosfatos metálicos y sistemas relacionados, utilizables como catalizadores en procesos orgánicos. Consta de tres partes, bien diferenciadas, pero relacionadas entre si: a) obtención de los ortofosfatos, siguiendo diferentes procedimientos. b) caracterización de los mismos, tanto desde el punto de vista estructural (xrd, tga-dta, sem- edax, etc.), como textural (drift, xps, porosimetria, etc.) y de propiedades ácido-básicas. c) utilización de los materiales, como catalizadores de una serie de procesos orgánicos "test" en fase gaseosa (transformación de alcoholes, alquilación de anilina con metanol, transferencia de hidrogeno, condensación entre acetofenona y metanol

Dynamic response of periodic infinite structure to arbitrary moving load based on the Finite Element Method

[EN] A common problem in railway engineering is the dynamic of repetitive structures subject to moving loads. Bridges, rails or catenaries are the most representative periodic structures, over which the train acts as a moving exciter. Usually, these structures are long enough to consider that their dynamic response is in permanent regime. To assume the steady-state regime some features have to be considered: infinite length structure, perfect periodicity and constant velocity of the moving load. This paper adopts these assumptions and provides the steady-state solution of a generic periodic structure subject to an arbitrary and also periodic moving load. The structure is divided into repetitive blocks modelled by the Finite Element Method. By applying the periodicity condition it is possible to consider the entire structure dynamics with only one block. The problem is stated in the frequency domain and moved back to time domain by means of Discrete Fourier Transform.The authors would like to acknowledge the financial support received from the Spanish Ministry of Economy, Industry and Competitiveness (TRA2017-84736-R).Gil-Romero, J.; Gregori, S.; Tur, M.; Fuenmayor, F. (2022). Dynamic response of periodic infinite structure to arbitrary moving load based on the Finite Element Method. En Proceedings of the YIC 2021 - VI ECCOMAS Young Investigators Conference. Editorial Universitat Politècnica de València. 326-333. https://doi.org/10.4995/YIC2021.2021.12606OCS32633

Practical considerations for clinical use of mesenchymal stem cells: From the laboratory to the horse

Since the clinical use of mesenchymal stem cells (MSCs) for treating musculoskeletal injuries is gaining popularity, practitioners should be aware of the factors that may affect MSCs from tissue harvesting for MSC isolation to cell delivery into the injury site. This review provides equine practitioners with up-to-date, practical knowledge for the treatment of equine patients using MSCs. A brief overview of laboratory procedures affecting MSCs is provided, but the main focus is on shipping conditions, routes of administration, injection methods, and which commonly used products can be combined with MSCs and which products should be avoided as they have deleterious effects on cells. There are still several knowledge gaps regarding MSC-based therapies in horses. Therefore, it is important to properly manage the factors which are currently known to affect MSCs, to further strengthen the evidence basis of this treatment

Differentiation of equine bone marrow derived mesenchymal stem cells increases the expression of immunogenic genes

Mesenchymal stem cells (MSCs) are a promising treatment for equine musculoskeletal injuries because of their ability to regulate the inflammation and to differentiate into other cell types. Since interest in allogeneic therapy is rising, concerns about MSC immunogenicity need to be addressed. Differentiated MSCs from several species increase their expression of immunogenic molecules and induce alloresponses, but equine MSC immunogenic profile after differentiation has not been reported. Therefore, the aim of this study was to assess the gene expression of immunogenic markers in tri-lineage differentiated equine bone marrow derived MSCs (eBM-MSCs). For this purpose, eBM-MSCs (n = 4) were differentiated into osteoblasts, adipocytes and chondrocytes. Differentiation was confirmed by specific staining and gene expression of lineage-related markers. Subsequently, gene expression of MHC-I, MHC-II, CD40 and CD80 was analyzed in undifferentiated (control) and tri-lineage differentiated eBM-MSCs. Osteogenesis and adipogenesis, but not chondrogenesis, significantly upregulated MHC-I; MHC-II expression significantly increased in the three lineages, while CD40 and CD80 expression did not change. Despite this, MHC-I and MHC-II upregulation after differentiation might lead to increased immunogenicity and risk of allorecognition, either eBM-MSCs differentiate in vivo after administration or they are differentiated prior to administration, with potential negative consequences for effectiveness and safety of allogeneic therapy

Efficient Removal of Nonylphenol Isomers from Water by Use of Organo-Hydrotalcites

The presence of potent organic endocrine-disrupting chemicals (EDCs) in natural aquifers can have adverse impacts on public health and the environment. 4-nonylphenol, one such EDC, can be efficiently removed from water by adsorption onto a clayey material. In this work, we created an effective sorbent for this purpose by using co-precipitation and subsequent ion-exchange to intercalate the organic anion deoxycholate into a Mg/Al hydrotalcite. Intercalating deoxycholate ions increased the organophilicity of the hydrotalcite surface. The solid was used to adsorb 4-nonylphenol at different pollutant concentrations and temperatures. The adsorption process was subjected to a kinetic study. Based on the results, the EDC was adsorbed by chemisorption. In addition, based on the equilibrium isotherms used for the process, the Freundlich model was the most accurate in reproducing the adsorption of 4-nonylphenol onto deoxycholate-intercalated hydrotalcite

Three-Dimensional Hierarchical Hydrotalcite–Silica Sphere Composites as Catalysts for Baeyer–Villiger Oxidation Reactions Using Hydrogen Peroxide

The development of effective, environmentally friendly catalysts for the Baeyer–Villiger reaction is becoming increasingly important in applied catalysis. In this work, we synthesized a 3D composite consisting of silica spheres coated with Mg/Al hydrotalcite with much better textural properties than its 2D counterparts. In fact, the 3D solid outperformed a 2D-layered hydrotalcite as catalyst in the Baeyer–Villiger reaction of cyclic ketones with H2O2/benzonitrile as oxidant. The 3D catalyst provided excellent conversion and selectivity; it was also readily filtered off the reaction mixture. The proposed reaction mechanism, which involves adsorption of the reactants on the hydrotalcite surface, is consistent with the catalytic activity results

Humoral immune response against allogeneic equine mesenchymal stem cells (MSCs) mediated by the major histocompatibility complex (MHC): an issue to take into account for the safety and efficacy of treatment with MSCs

Allogeneic mesenchymal stem cells (MSCs) present several advantages, but recipient immune response needs to be further elucidated. Proinflammatory priming of MSCs activated their in vivo regulatory capacity, but repeated administrations led to slight inflammatory reaction in an osteoarthritis equine model. This may be associated with higher major histocompatibility complex (MHC) expression, which would increase MSC immunogenicity potentially inducing humoral mediated immune memory. This study aimed at assessing allo-antibody production against donor’s equine MHC (equine leukocyte antigen, ELA) in animals that received intra-articular repeated administration of allogeneic MSC-primed. For this purpose, we used stored samples from a previous study. Donor and recipients ELA-haplotypes were stablished by microsatellite typing and complementmediated microcytoxicity assays were carried out by exposing target cells from the donor (unstimulated MSCs [MSC-nai¨ve], MSC-primed or lymphocytes [control]) to sera collected at different time-points from 10 recipients: ELA-mismatched MSCnai ¨ve recipients, ELA-mismatched MSC-primed recipients or ELA-partially matched MSC-primed recipients. All animals receiving allogeneic MSCs produced allo-antibodies after the first injection, regardless of the matching degree. However, antibody peak production after second administration was only observed in ELA-mismatched recipients, both of MSC-nai¨ve and MSCprimed. Horses injected with MSC-primed produced fewer antibodies but MSC-primed were more targeted in the microcytoxicity assay. Thus, activated immunomodulatory profile of MSC-primed could have led to slighter humoral response after ..