1,720 research outputs found

    Análisis de proyección y fortalecimiento empresarial Expinn Technology SAS

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    Trabajo de investigaciónSe realiza el análisis financiero de la empresa EXPINN TECHNOLOGY SAS con NIT 900.794.112-8 según su RUT, con el fin de identificar su situación económica actual y de este modo ejecutar la aplicación de un método de proyección a un plazo de cinco (5) años para poder analizar la viabilidad en cuanto a crecimiento y expansión en el mercado, teniendo en cuenta las diferentes variables macroeconómicas de financiación y del entorno; además, del análisis de tres (3) escenarios diferentes de viabilidad, que permitan establecer el escenario óptimo de inversión y crecimiento, a partir de la ejecución de las estrategias requeridas para tal fin.Introducción 1. Planteamiento del Problema7 2. Objetivos 3. Marco de Referencia 4. Metodología 5. Resultados 6. Análisis financiero general 7. Indicadores 8. Proyección Financiera Conclusiones ReferenciasEspecializaciónEspecialista en Análisis y Administración Financier

    Modelo estratégico integral para la implementación del Sistema de Gestión de la Seguridad y Salud en el Trabajo (SG-SST), en la Empresa Adecco

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    Modelo estratégico integral para la implementación del sistema de gestión de la seguridad y salud en el trabajo (sg-sst), en la empresa adecco, en busca de mejorar la problematica en cuanto a la mala iluminación y la poca o nula capacidad para el manejo de incendiosIntegral strategic model for the implementation of the occupational safety and health management system (sg-sst), in the Adecco company, in order to improve the problematic in terms of poor lighting and little or no capacity for management fir

    La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia; departamento de Boyacá

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    Dentro de nuestra labor psicosocial vemos como a partir de experiencias constructivas determinadas en cada uno de nuestros entornos, se integran acciones de memoria significativas al incorporar como instrumento crucial la foto voz siendo este la principal narrativa vivencial de diversos tipos de violencias tales como: la exclusión social, el desplazamiento forzado, conflicto armado, guerras, reclutamiento ilícitos y demás hechos de desigualdad entorno a la vulneración de derechos propios de las personas. Siendo esto la principal causa para incidir en la prevención de la violencia, ya que esta se reduce considerablemente al integrar acciones en vinculación para con la educación y la promoción de valores como la tolerancia, el respeto y la resolución pacífica de conflictos. A partir de ello identificamos y abordamos las causas subyacentes de la violencia, al ser el impulso para determinar acciones psicosociales que benefician el tratamiento de las comunidades, familias y personas que han sido vilmente perjudicadas. Con el trabajo interdisciplinar ejercido en la labor psicosocial se busca generar un análisis sustancioso para mitigar los impactos psíquicos, y sociales que con lleva la reflexión dada en el caso de la comisión de la verdad fomentando así la reducción de los efectos negativos asociados con salud mental de las víctimas. Desde el apoyo social y reconociendo las necesidades individuales de cada persona al ser una la labor eficaz que nos permite reducir la sensación de aislamiento y mejorar la resiliencia emocional de las personas afectadas.Within our psychosocial work we see how, based on constructive experiences determined in each of our environments, significant memory actions are integrated by incorporating the photovoice as a crucial instrument, this being the main experiential narrative of various types of violence such as: exclusion social, forced displacement, armed conflict, wars, illegal recruitment and other acts of inequality related to the violation of people's own rights. This being the main cause to influence the prevention of violence, since this is considerably reduced by integrating actions in connection with education and the promotion of values such as tolerance, respect and the peaceful resolution of conflicts. From this we identify and address the underlying causes of violence, as it is the impulse to determine psychosocial actions that benefit the treatment of communities, families and people who have been vilely harmed. With the interdisciplinary work carried out in psychosocial work, the aim is to generate a substantial analysis to mitigate the psychological and social impacts that the reflection given in the case of the truth commission entails, thus promoting the reduction of the negative effects associated with mental health. of the victims. From social support and recognizing the individual needs of each person as it is an effective task that allows us to reduce the feeling of isolation and improve the emotional resilience of the affected people

    Latin American study of hereditary breast and ovarian cancer LACAM : a genomic epidemiology approach

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    Q2Q1Artículo original1-13Purpose: Hereditary Breast and Ovarian Cancer (HBOC) syndrome is responsible for ~5–10% of all diagnosed breast and ovarian cancers. Breast cancer is the most common malignancy and the leading cause of cancer-related mortality among women in Latin America (LA). The main objective of this study was to develop a comprehensive understanding of the genomic epidemiology of HBOC throughout the establishment of The Latin American consortium for HBOC-LACAM, consisting of specialists from 5 countries in LA and the description of the genomic results from the first phase of the study. Methods: We have recruited 403 individuals that fulfilled the criteria for HBOC from 11 health institutions of Argentina, Colombia, Guatemala, Mexico and Peru. A pilot cohort of 222 individuals was analyzed by NGS gene panels. One hundred forty-three genes were selected on the basis of their putative role in susceptibility to different hereditary cancers. Libraries were sequenced in MiSeq (Illumina, Inc.) and PGM (Ion Torrent-Thermo Fisher Scientific) platforms. Results: The overall prevalence of pathogenic variants was 17% (38/222); the distribution spanned 14 genes and varied by country. The highest relative prevalence of pathogenic variants was found in patients from Argentina (25%, 14/57), followed by Mexico (18%, 12/68), Guatemala (16%, 3/19), and Colombia (13%, 10/78). Pathogenic variants were found in BRCA1 (20%) and BRCA2 (29%) genes. Pathogenic variants were found in other 12 genes, including high and moderate risk genes such as MSH2, MSH6, MUTYH, and PALB2. Additional pathogenic variants were found in HBOC unrelated genes such as DCLRE1C, WRN, PDE11A, and PDGFB. Conclusion: In this first phase of the project, we recruited 403 individuals and evaluated the germline genetic alterations in an initial cohort of 222 patients among 4 countries. Our data show for the first time in LA the distribution of pathogenic variants in a broad set of cancer susceptibility genes in HBOC. Even though we used extended gene panels, there was still a high proportion of patients without any detectable pathogenic variant, which emphasizes the larger, unexplored genetic nature of the disease in these populations

    Identification of heavy-flavour jets with the CMS detector in pp collisions at 13 TeV

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    Many measurements and searches for physics beyond the standard model at the LHC rely on the efficient identification of heavy-flavour jets, i.e. jets originating from bottom or charm quarks. In this paper, the discriminating variables and the algorithms used for heavy-flavour jet identification during the first years of operation of the CMS experiment in proton-proton collisions at a centre-of-mass energy of 13 TeV, are presented. Heavy-flavour jet identification algorithms have been improved compared to those used previously at centre-of-mass energies of 7 and 8 TeV. For jets with transverse momenta in the range expected in simulated tt\mathrm{t}\overline{\mathrm{t}} events, these new developments result in an efficiency of 68% for the correct identification of a b jet for a probability of 1% of misidentifying a light-flavour jet. The improvement in relative efficiency at this misidentification probability is about 15%, compared to previous CMS algorithms. In addition, for the first time algorithms have been developed to identify jets containing two b hadrons in Lorentz-boosted event topologies, as well as to tag c jets. The large data sample recorded in 2016 at a centre-of-mass energy of 13 TeV has also allowed the development of new methods to measure the efficiency and misidentification probability of heavy-flavour jet identification algorithms. The heavy-flavour jet identification efficiency is measured with a precision of a few per cent at moderate jet transverse momenta (between 30 and 300 GeV) and about 5% at the highest jet transverse momenta (between 500 and 1000 GeV)

    Search for heavy resonances decaying to a top quark and a bottom quark in the lepton+jets final state in proton–proton collisions at 13 TeV

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    info:eu-repo/semantics/publishe

    Evidence for the Higgs boson decay to a bottom quark–antiquark pair

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    info:eu-repo/semantics/publishe

    Pseudorapidity and transverse momentum dependence of flow harmonics in pPb and PbPb collisions

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    info:eu-repo/semantics/publishe

    Measurement of differential cross sections for top quark pair production using the lepton plus jets final state in proton-proton collisions at 13 TeV

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    National Science Foundation (U.S.

    Particle-flow reconstruction and global event description with the CMS detector

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    The CMS apparatus was identified, a few years before the start of the LHC operation at CERN, to feature properties well suited to particle-flow (PF) reconstruction: a highly-segmented tracker, a fine-grained electromagnetic calorimeter, a hermetic hadron calorimeter, a strong magnetic field, and an excellent muon spectrometer. A fully-fledged PF reconstruction algorithm tuned to the CMS detector was therefore developed and has been consistently used in physics analyses for the first time at a hadron collider. For each collision, the comprehensive list of final-state particles identified and reconstructed by the algorithm provides a global event description that leads to unprecedented CMS performance for jet and hadronic tau decay reconstruction, missing transverse momentum determination, and electron and muon identification. This approach also allows particles from pileup interactions to be identified and enables efficient pileup mitigation methods. The data collected by CMS at a centre-of-mass energy of 8 TeV show excellent agreement with the simulation and confirm the superior PF performance at least up to an average of 20 pileup interactions
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