763 research outputs found

    Applying Word Processing Comptencies in Two Academic Subjects

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    This project was developed with the intent of bringing academic and vocational curriculum together. The purpose of the project was to illustrate to students the connections between the skills they develop in word processing with the information they receive in two academic courses: Pacific Northwest History and Biology. Units were developed to reinforce the word processors\u27 keyboarding skills while introducing them to science or social studies concepts and issues. Conversely, science and social studies students were exposed to the benefits of using a computer in their endeavors. A secondary purpose of this project was to develop skills in working together. This was achieved by creating units where science or history students worked with a word processing student on IBM computers. Assignments required documents of particular science or social studies units to be printed in correct word processing format

    Interview with Marvin Strahmeier and Effie Sumner Fuller

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    An interview with Marvin Strahmeier regarding the early days of Hays, KS, and Effie Sumner Fuller regarding the early history of Nicodemus, KS The introduction is missing. 00:00:05 - Marvin Strahmeier, immigrating to the United States from Germany 00:00:57 - Hays, KS in 1886 00:02:33 - Schools in Hays 00:04:07 - Herding cattle for the Barry family 00:05:05 - Molasses mill at Hays 00:07:02 - Going to work for John Orth and the geography around Schoenchen, KS 00:08:41 - Farm houses and sod houses 00:09:20 - Going to work for John Kelly in 1890 and the flood in the fall of 1890 00:11:09 - School experience 00:12:12 - Marrying his wife in 1905 00:13:36 - Old Settler\u27s Picnic 00:16:07 - Serving in the Army during the Spanish American War 00:18:54 - Homesteading on the Smoky Hill River in 1904 00:20:10 - Rattlesnake under the baby buggy 00:22:42 - Fishing in Big Creek as a boy 00:24:08 - Wages for herding cattle in the 1890s 00:25:43 - Harvest crew struck by lightning in 1897 00:30:07 - Prairie fire in 1897 00:31:14 - Driving to surrounding towns 00:35:50 - Livery barns in Hays 00:38:53 - Mrs. Effie Green Sumner Fuller, African American teacher, and daughter of former slaves, interview introduction 00:39:21 - Father\u27s service as an African American soldier during the Civil War 00:40:30 - Mother\u27s early life in Texas 00:40:50 - Experience with Indigenous American leaders at Ft. Leavenworth 00:41:11 - Personal background 00:41:48 - Life in early Nicodemus, KS 00:44:45 - Song, Go Down To The Water (African American baptismal hymn) 00:45:52 - Politicians at the Emancipation celebration in Nicodemus 00:49:27 - Changes in Nicodemus over the years 00:50:00 - Two Nicodemus families moving back to Africa 00:50:54 - Marrying Lorenzo Fuller in 1916 and husband\u27s entertainer career with the Fuller Concert Company 00:55:20 - Travels 00:55:54 - Son, actor and performer, Lorenzo Fuller Jr. 00:58:26 - Song on organ chime bells, Old Black Joe 01:00:00 - Song, Go Down, Moses 01:01:19 - Song, Steal Away Home 01:02:51 - O.T. Medder, minister of the Congregational church in Stockton on meeting the Fullers 01:04:24 - Religious life in Nicodemus 01:05:21 - African American religious community in Stockton 01:06:26 - Masonic Lodge in Nicodemus 01:07:08 - African American funeralshttps://scholars.fhsu.edu/sackett/1042/thumbnail.jp

    A review of the prevalence of physical activity in health professional undergraduate, postgraduate, pre qualification courses and Continuous Professional Development activities

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    'Let's Make Scotland More Active' was published in 2003 by the then Scottish Executive and sets out the recommendations for increasing levels of physical activity (PA) within the population. One of the key strategy recommendations was that all patients coming into contact with primary care professionals should be offered screening and appropriate counselling for PA tailored to individual needs (paragraph 142). NHS Health Scotland has a range of existing and planned learning products and services aimed at influencing knowledge, attitudes and behaviour in the area of physical activity among the practitioner and wider health improvement workforces. These resources and services seek to encourage health professionals to increasingly deliver PA brief advice as an intervention in the care of their patients. However, it is not clear whether they are being used, or indeed the extent to which physical activity and its benefits are being taught to health professionals during undergraduate, post graduate and CPD training

    Employing patient-reported outcome (PRO) measures to support newly diagnosed patients with melanoma: feasibility and acceptability of a holistic needs assessment intervention

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    Purpose: Living with a melanoma diagnosis can be challenging. We aimed to assess the feasibility, acceptability, and perceived value of a nurse-led intervention that utilised patient-reported outcome (PRO) measures to identify and address the supportive care needs of newly diagnosed patients with Stage I/II melanoma over the first 4 months post-diagnosis. Methods: We conducted an exploratory, repeated-measures, single-arm, feasibility trial. One baseline (4 weeks post-diagnosis; T1) and one follow-up intervention session (4 weeks after wide local excision; T3) took place, two months apart. Patient survey data were collected monthly, at four assessment points (T1-T4), followed by exit interviews. Results: A recruitment rate of 55% (10/18) was achieved. The skin cancer nurse specialist (CNS) performed 19 in-clinic patient assessments within 6 months. One patient missed their follow-up intervention session (90% retention rate). Three participants (30%) were lost to follow-up at T4. Patients endorsed the standardised use of easy-to-use PRO measures as a means to help them shortlist, report and prioritise their needs. The CNS viewed the intervention as a highly structured activity that allowed tailoring support priority needs. A sizeable reduction in information needs was found from T1 to T4 (Standardised Response Mean [SRM] change = −0.99; p < 0.05). From T1 to T2, significant reductions in psychological (SRM change = −1.18; p < 0.001), practical (SRM change = −0.67; p < 0.05) and sexuality needs (SRM change = −0.78; p < 0.05) were observed. Conclusions: The intervention appears to be feasible in clinical practice and acceptable to both patients with newly diagnosed melanoma and clinicians. Future research is warranted to test its effectiveness against standard care

    A comparison of patient education practices of novice and experienced physiotherapists in Australia

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    Background: Patient education is an integral component of physiotherapy practice. Little is known about the differences in reported use and perception of patient education between experienced and novice physiotherapists. Understanding these differences has important implications for training approaches and physiotherapy practice

    Very long chain fatty acid metabolism is required in acute myeloid leukemia

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    Acute myeloid leukemia (AML) cells have an atypical metabolic phenotype characterized by increased mitochondrial mass, as well as a greater reliance on oxidative phosphorylation and fatty acid oxidation (FAO) for survival. To exploit this altered metabolism, we assessed publicly available databases to identify FAO enzyme overexpression. Very long chain acyl-CoA dehydrogenase (VLCAD; ACADVL) was found to be overexpressed and critical to leukemia cell mitochondrial metabolism. Genetic attenuation or pharmacological inhibition of VLCAD hindered mitochondrial respiration and FAO contribution to the tricarboxylic acid cycle, resulting in decreased viability, proliferation, clonogenic growth, and AML cell engraftment. Suppression of FAO at VLCAD triggered an increase in pyruvate dehydrogenase activity that was insufficient to increase glycolysis but resulted in adenosine triphosphate depletion and AML cell death, with no effect on normal hematopoietic cells. Together, these results demonstrate the importance of VLCAD in AML cell biology and highlight a novel metabolic vulnerability for this devastating disease

    Cohort profile: The Scottish Research Register SHARE. A register of people interested in research participation linked to NHS datasets

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    SHARE is a NHS Scotland Research (NRS) infrastructure initiative and is funded by the Chief Scientists Office of the Scottish Government. Additional funding and initiation of the spare blood retention in Tayside was supported by The Wellcome Trust Biomedical Resource Award Number 099177/Z/12/Z.Purpose: Recruitment to trials is often difficult. Many trials fail to meet recruitment targets resulting in underpowered studies which waste resources and the time of those who participated. While there is evidence that many people are willing to take part in research, particularly if it involves a condition from which they suffer, researchers are unable to easily contact such people often relying on busy clinicians to identify them. Many clinicians perceive themselves as too busy to take part in research activities. The Scottish Health Research Register SHARE adopts an approach which asks the public to consent to their data held in National Health Service databases to be used to determine their suitability for research projects. Additionally, participants can consent for spare blood, left after routine venepuncture to be automatically identified in the laboratory and stored for future research studies. Participants: Anyone over the age of 16 years in Scotland can participate. Participants are approached through a range of methods including directly at outpatient clinics and general practitioners practices, leaflets with hospital letters and personal email from employers. Findings to date: SHARE has recruited around 130 000 people. SHARE has demonstrated that it can quickly and efficiently recruit to studies, over 20 until now. In addition, it can be used to administer questionnaire studies by email and recruit to patient and public involvement groups. Future plans: SHARE continues to steadily recruit with the ambition of eventually achieving 1 000 000 people in Scotland. We are steadily increasing the number of data sets we use for identifying participants. We are adding a mobile app which will facilitate dissemination about research and allow the collection of physiological and activity data if desired. We anticipate that SHARE will soon become the main source of health research recruitment in Scotland.Publisher PDFPeer reviewe

    Best practice coral restoration for the Great Barrier Reef

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    As the Great Barrier Reef (GBR) continues to degrade through repeated mass bleaching events, crown-of-thorns starfish and major disease outbreaks, and the impacts of intense cyclones, pressure is growing for direct intervention to assist the recovery of reef-building corals. Decreasing coral cover on the GBR and other Australian reefs has been recognised as a serious problem relatively recently in Australia but follows a global trend, with many overseas reefs now highly degraded. Various types of coral restoration, rehabilitation and assisted recovery projects have been trialled overseas for decades and it makes sense to look at what has and hasn’t worked overseas to determine a range of options that may suit GBR conditions. Some direct interventions to assist coral recovery have been trialled in Australia such as transplanting corals, algae removal to promote coral recovery and larval enhancement promoting direct coral recruitment. In addition, after physical damage from cyclones, ship strikes or dragged anchors, local dive operators and dive clubs (permitted or unpermitted) often attempt to assist the recovery of corals by tipping over flipped tabular corals and reattaching broken branching corals or sea fans. These latter assisted recovery techniques are rarely underpinned by scientific data on coral recovery. A lack of best practice guidelines for these actions limits the chance of success and increases the health and safety risks of these activities

    Exposure to environmental stressors result in increased viral load and further reduction of production parameters in pigs experimentally infected with PCV2b

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    Porcine circovirus type 2 (PCV2) has been identified as the essential, but not sole, underlying infectious component for PCV-associated diseases (PCVAD). Several co-factors have been suggested to convert an infection with PCV2 into the clinical signs of PCVAD, including co-infection with a secondary pathogen and the genetic background of the pig. In the present study, we investigated the role of environmental stressors in the form of changes in environmental temperature and increased stocking-density on viral load in serum and tissue, average daily weight gain (ADG) and food conversion rate (FCR) of pigs experimentally infected with a defined PCV2b strain over an eight week period. These stressors were identified recently as risk factors leading to the occurrence of severe PCVAD on a farm level. In the current study, PCV2-free pigs were housed in separate, environmentally controlled rooms, and the experiment was performed in a 2 × 2 factorial design. In general, PCV2b infection reduced ADG and increased FCR, and these were further impacted on by the environmental stressors. Furthermore, all stressors led to an increased viral load in serum and tissue as assessed by qPCR, although levels did not reach statistical significance. Our data suggest that there is no need for an additional pathogen to develop PCVAD in conventional status pigs, and growth retardation and clinical signs can be induced in PCV2 infected pigs that are exposed to environmental stressors alone
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