Analytical and Numerical Solutions of Nonlinear Differential Equations Arising in Non-Newtonian Fluid Flows

AbstractSolutions for a class of nonlinear second order differential equations, arising in a viscoelastic fluid flow at a rotating cylinder, are obtained. Furthermore, using the Shauder theory and the perturbation technique existence, uniqueness and analyticity results are established. Moreover, the exact analytical solutions (in integral form) are compared with the corresponding numerical ones

Steady Hall Magnetohydrodynamics Near a X-type Magnetic Neutral Line

Hall magnetohydrodynamics (MHD) properties near a two-dimensional (2D) X-type magnetic neutral line in the steady state are considered via heuristic and rigorous developments. Upon considering the steady-state as the asymptotic limit of the corresponding \textit{time-dependent} problem and using a rigorous development, Hall effects are shown to be able to sustain the hyperbolicity of the magnetic field (and hence a more open X-point configuration) near the neutral line in the steady state. The heuristic development misses this subtle connection of the steady state with the corresponding \textit{time-dependent} problem and predicts only an elongated current-sheet configuration (as in resistive MHD). However, the heuristic development turns out to be useful in providing insight into the lack of dependence of the reconnection rate on the mechanism breaking the frozen-in condition of the magnetic field lines. The latter result can be understood in terms of the ability of the ions and electrons to transport equal amounts of magnetic flux per unit time out of the reconnection region.Comment: 1-10 page

Amphibian Immune Defenses against Chytridiomycosis: Impacts of Changing Environments

Eco-immunology is the field of study that attempts to understand the functions of the immune system in the context of the host's environment. Amphibians are currently suffering devastating declines and extinctions in nearly all parts of the world due to the emerging infectious disease chytridiomycosis caused by the chytrid fungus, Batrachochytrium dendrobatidis. Because chytridiomycosis is a skin infection and remains confined to the skin, immune defenses of the skin are critical for survival. Skin defenses include secreted antimicrobial peptides and immunoglobulins as well as antifungal metabolites produced by symbiotic skin bacteria. Low temperatures, toxic chemicals, and stress inhibit the immune system and may impair natural defenses against B. dendrobatidis. Tadpoles' mouth parts can be infected by B. dendrobatidis. Damage to the mouth parts can impair growth, and the affected tadpoles maintain the pathogen in the environment even when adults have dispersed. Newly metamorphosing frogs appear to be especially vulnerable to infection and to the lethal effects of this pathogen because the immune system undergoes a dramatic reorganization at metamorphosis, and postmetamorphic defenses are not yet mature. Here we review our current understanding of amphibian immune defenses against B. dendrobatidis and the ability of the pathogen to resist those defenses. We also briefly review what is known about the impacts of temperature, environmental chemicals, and stress on the host-pathogen interactions and suggest future directions for researc

Joint searches between gravitational-wave interferometers and high-energy neutrino telescopes: science reach and analysis strategies

Many of the astrophysical sources and violent phenomena observed in our Universe are potential emitters of gravitational waves (GWs) and high-energy neutrinos (HENs). A network of GW detectors such as LIGO and Virgo can determine the direction/time of GW bursts while the IceCube and ANTARES neutrino telescopes can also provide accurate directional information for HEN events. Requiring the consistency between both, totally independent, detection channels shall enable new searches for cosmic events arriving from potential common sources, of which many extra-galactic objects.Comment: 4 pages. To appear in the Proceedings of the 2d Heidelberg Workshop: "High-Energy Gamma-rays and Neutrinos from Extra-Galactic Sources", Heidelberg (Germany), January 13-16, 200

Benefits of Artificially Generated Gravity Gradients for Interferometric Gravitational-Wave Detectors

We present an approach to experimentally evaluate gravity gradient noise, a potentially limiting noise source in advanced interferometric gravitational wave (GW) detectors. In addition, the method can be used to provide sub-percent calibration in phase and amplitude of modern interferometric GW detectors. Knowledge of calibration to such certainties shall enhance the scientific output of the instruments in case of an eventual detection of GWs. The method relies on a rotating symmetrical two-body mass, a Dynamic gravity Field Generator (DFG). The placement of the DFG in the proximity of one of the interferometer's suspended test masses generates a change in the local gravitational field detectable with current interferometric GW detectors.Comment: 16 pages, 4 figure

Delayed ethylene glycol poisoning presenting with abdominal pain and multiple cranial and peripheral neuropathies: a case report

<p>Abstract</p> <p>Introduction</p> <p>Ethylene glycol poisoning may pose diagnostic difficulties if the history of ingestion is not volunteered, or if the presentation is delayed. This is because the biochemical features of high anion-gap metabolic acidosis and an osmolar gap resolve within 24 to 72 hours as the ethylene glycol is metabolized to toxic metabolites. This case illustrates the less well-known clinical features of delayed ethylene glycol poisoning, including multiple cranial and peripheral neuropathies, and the clinical findings which may point towards this diagnosis in the absence of a history of ingestion.</p> <p>Case presentation</p> <p>A 53-year-old Afro-Caribbean man presented with vomiting, abdominal pain and oliguria, and was found to have acute renal failure requiring emergency hemofiltration, and raised inflammatory markers. Computed tomography imaging of the abdomen revealed the appearance of bilateral pyelonephritis, however he failed to improve with broad-spectrum antibiotics, and subsequently developed multiple cranial neuropathies and increasing obtundation, necessitating intubation and ventilation. Computed tomography of the brain showed no focal lesions, and a lumbar puncture revealed a raised cerebrospinal fluid opening pressure and cyto-albuminological dissociation. Nerve conduction studies revealed a sensorimotor radiculoneuropathy mimicking a Guillain-Barre type lesion with an atypical distribution. It was only about two weeks after presentation that the history of ethylene glycol ingestion one week before presentation was confirmed. He had a slow recovery on the intensive care unit, requiring renal replacement therapy for eight weeks, and complicated by acute respiratory distress syndrome, neuropathic pain and a slow neurological recovery requiring prolonged rehabilitation.</p> <p>Conclusions</p> <p>Although neuropathy as a result of ethylene glycol poisoning has been described in a few case reports, all of these were in the context of a known history of ingestion. As the diagnosis may well be obscured if the history of ingestion is not elucidated, it is important to be aware of this possibility especially if presentation is delayed.</p

Concurrent invasions by European starlings (Sturnus vulgaris) suggest selection on shared genomic regions even after genetic bottlenecks

A species’ success during the invasion of new areas hinges on an interplay between the demographic processes common to invasions and the specific ecological context of the novel environment. Evolutionary genetic studies of invasive species can investigate how genetic bottlenecks and ecological conditions shape genetic variation in invasions, and our study pairs two invasive populations that are hypothesized to be from the same source population to compare how each population evolved during and after introduction. Invasive European Starlings (Sturnus vulgaris) established populations in both Australia and North America in the 19th century. Here, we compare whole-genome sequences among native and independently introduced European Starling populations to determine how demographic processes interact with rapid evolution to generate similar genetic patterns in these recent and replicated invasions. Demographic models indicate that both invasive populations experienced genetic bottlenecks as expected based on invasion history, and we find that specific genomic regions have differentiated even on this short evolutionary timescale. Despite genetic bottlenecks, we suggest that genetic drift alone cannot explain differentiation in at least two of these regions. The demographic boom intrinsic to many invasions as well as potential inversions may have led to high population-specific differentiation, although the patterns of genetic variation are also consistent with the hypothesis that this infamous and highly mobile invader adapted to novel selection (e.g., extrinsic factors). We use targeted sampling of replicated invasions to identify and evaluate support for multiple, interacting evolutionary mechanisms that lead to differentiation during the invasion process

Mid-term cost-effectiveness analysis of open and endovascular repair for ruptured abdominal aortic aneurysm

AbstractBackgroundEmergency endovascular repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA) may have lower operative mortality rates than open surgical repair. Concerns remain that the early survival benefit after EVAR for rAAA may be offset by late reinterventions. The aim of this study was to compare reintervention rates and cost-effectiveness of EVAR and open repair for rAAA.MethodsA retrospective analysis was undertaken of patients with rAAA undergoing EVAR or open repair over 6 years. A health economic model developed for the cost-effectiveness of elective EVAR was used in the emergency setting.ResultsSixty-two patients (mean age 77·9 years) underwent EVAR and 85 (mean age 75·9 years) had open repair of rAAA. Median follow-up was 42 and 39 months respectively. There was no significant difference in 30-day mortality rates after EVAR and open repair (18 and 26 per cent respectively; P = 0·243). Reintervention rates were also similar (32 and 31 per cent; P = 0·701). The mean cost per patient was €26 725 for EVAR and €30 297 for open repair, and the cost per life-year gained was €7906 and €9933 respectively (P = 0·561). Open repair had greater initial costs: longer procedural times (217 versus 178·5 min; P &amp;lt; 0·001) and intensive care stay (5·0 versus 1·0 days; P = 0·015). Conversely, EVAR had greater reintervention (€156 939 versus €35 335; P = 0·001) and surveillance (P &amp;lt; 0·001) costs.ConclusionThere was no significant difference in reintervention rates after EVAR or open repair for rAAA. EVAR was as cost-effective at mid-term follow-up. The increased procedural costs of open repair are not outweighed by greater surveillance and reintervention costs after EVAR.</jats:sec