24 research outputs found
Future Facilities Summary
For the session on future facilities at DIS09 discussions were organized on
DIS related measurements that can be expected in the near and medium - or
perhaps far - future, including plans from JLab, CERN and FNAL fixed target
experiments, possible measurements and detector upgrades at RHIC, as well as
the plans for possible future electron proton/ion colliders such as the EIC and
the LHeC project.Comment: Summary of the parallel sessions on future facilities and the plenary
discussion session on possible future electron proton/ion colliders such as
the EIC and the LHeC project at the Deep Inelastic Scattering workshop in
Madrid, April 200
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Probing the Quark Sea and Gluons: the Electron-Ion Collider Projects
EIC is the generic name for the nuclear science-driven Electron-Ion Collider presently considered in the US. Such an EIC would be the world’s first polarized electron-proton collider, and the world’s first e-A collider. Very little remains known about the dynamical basis of the structure of hadrons and nuclei in terms of the fundamental quarks and gluons of Quantum Chromodynamics (QCD). A large community effort to sharpen a compelling nuclear science case for an EIC occurred during a ten-week program taking place at the Institute for Nuclear Theory (INT) in Seattle from September 13 to November 19, 2010. The critical capabilities of a stage-I EIC are a range in center-of-mass energies from 20 to 70 GeV and variable, full polarization of electrons and light ions (the latter both longitudinal and transverse), ion species up to A=200 or so, multiple interaction regions, and a high luminosity of about 10{sup 34} electron-nucleons per cm{sup 2} and per second. The physics program of such a stage-I EIC encompass inclusive measurements (ep/A{yields}e'+X), which require detection of the scattered lepon and/or the full scattered hadronic debris with high precision, semi-inclusive processes (ep/A{yields}e'+h+X), which require detection in coincidence with the scattered lepton of at least one (current or target region) hadron; and exclusive processes (ep/A{yields}e'+N'/A'+{gamma}/m), which require detection of all particles in the reaction. The main science themes of an EIC are to i) map the spin and spatial structure of quarks and gluons in nucleons, ii) discover the collective effects of gluons in atomic nuclei, and (iii) understand the emergence of hadronic matter from color charge. In addition, there are opportunities at an EIC for fundamental symmetry and nucleon structure measurements using the electroweak probe. To truly make headway to image the sea quarks and gluons in nucleons and nuclei, the EIC needs high luminosity over a range of energies as more exclusive scattering probabilities are small, and any integrated detector/interaction region design needs to provide uniform coverage to detect spectator and diffractive products. This is because e-p and even more e-A colliders have a large fraction of their science related to what happens to the nucleon or ion beams. As a result, the philosophy of integration of complex detectors into an extended interaction region faces challenging constraints. Designs feature crossing angles between the protons or heavy ions during collisions with electrons, to remove potential problems for the detector induced by synchrotron radiation. Designs allocate quite some detector space before the final-focus ion quads, at the cost of luminosity, given that uniform detection coverage is a must for deep exclusive and diffractive processes. The integrated EIC detector/interaction region design at JLab focused on establishing full acceptance for such processes over a wide range of proton energies (20-100 GeV) with well achievable interaction region magnets. The detector design at BNL uses the higher ion beam energies to achieve good detection efficiency for instance for protons following a DVCS reaction, for proton beam energies starting from 100 GeV. Following a recommendation of the 2007 US Nuclear Science Long-Range Planning effort, the DOE Office of Nuclear Physics (DOE/NP) has allocated accelerator R&D funds to lay the foundation for a polarized EIC. BNL, in association with JLab and DOE/NP, has also established a generic detector R&D program to address the scientific requirements for measurements at a future EIC
Infant RSV immunoprophylaxis changes nasal epithelial DNA methylation at 6 years of age
BackgroundRespiratory syncytial virus (RSV) infection has been associated with childhood wheeze and asthma, and potential mechanisms include persistent epigenetic effects.MethodsIn the randomized, placebo-controlled MAKI trial, 429 preterm infants randomly received RSV immunoprophylaxis with palivizumab or placebo during their first RSV season. Children were followed until age 6 for asthma evaluation. DNA methylation in cells obtained by nasal brushes at age 6 was measured by Illumina MethylationEPIC array.ResultsRSV immunoprophylaxis in infancy had a significant impact on global methylation patterns in nasal cells at age 6. The first principal component (PC) related to the immunoprophylaxis intervention was enriched for the pathway "detection of chemical stimulus involved in sensory perception of smell" and "T cell differentiation." Subsequent analysis of these PCs indicated an effect of RSV immunoprophylaxis on cell type composition of nasal brushed cells. Three CpG sites, cg18040241, cg08243963, and cg19555973 which are annotated to genes GLB1L2, SC5D, and BPIFB1, were differentially methylated at genome-wide significance, but were not associated with asthma. ConclusionThe study provides the first proof of concept that RSV immunoprophylaxis during infancy has long-term effects on nasal epigenetic signatures at age 6, relating to host sensory perception, epidermal growth factor receptor signaling, and adaptive immune responses.</p
Physics Opportunities with the 12 GeV Upgrade at Jefferson Lab
This white paper summarizes the scientific opportunities for utilization of
the upgraded 12 GeV Continuous Electron Beam Accelerator Facility (CEBAF) and
associated experimental equipment at Jefferson Lab. It is based on the 52
proposals recommended for approval by the Jefferson Lab Program Advisory
Committee.The upgraded facility will enable a new experimental program with
substantial discovery potential to address important topics in nuclear,
hadronic, and electroweak physics.Comment: 64 page
Pion and kaon structure at the electron-ion collider
Understanding the origin and dynamics of hadron structure and in turn that of atomic nuclei is a central goal of nuclear physics. This challenge entails the questions of how does the roughly 1GeV mass-scale that characterizes atomic nuclei appear; why does it have the observed value; and, enigmatically, why are the composite Nambu-Goldstone (NG) bosons in quantum chromodynamics (QCD) abnormally light in comparison? In this perspective, we provide an analysis of the mass budget of the pion and proton in QCD; discuss the special role of the kaon, which lies near the boundary between dominance of strong and Higgs mass-generation mechanisms; and explain the need for a coherent effort in QCD phenomenology and continuum calculations, in exa-scale computing as provided by lattice QCD, and in experiments to make progress in understanding the origins of hadron masses and the distribution of that mass within them. We compare the unique capabilities foreseen at the electron-ion collider (EIC) with those at the hadron-electron ring accelerator (HERA), the only previous electron-proton collider; and describe five key experimental measurements, enabled by the EIC and aimed at delivering fundamental insights that will generate concrete answers to the questions of how mass and structure arise in the pion and kaon, the Standard Model's NG modes, whose surprisingly low mass is critical to the evolution of our Universe
TMDs and GPDs at a future Electron-Ion Collider
In the U.S., an Electron-Ion Collider (EIC) of energy -100 GeV is under design, with two options studied at Brookhaven National Lab and Jefferson Laboratory. The recent 2015 US Nuclear Science Long-Range Planning effort included a future EIC as a recommendation for future construction. The EIC will be unique in colliding polarised electrons off polarised protons and light nuclei, providing the spin degrees of freedom essential to pursue its physics program driven by spin structure, multi-dimensional tomographic images of protons and nuclei, and discovery of the role of collective effects of gluons in nuclei. The foreseen luminosity of the EIC, coupled with its energy variability and reach, will allow unprecedented three-dimensional imaging of the gluon and sea quark distributions, via both TMDs and GPDs, and to explore correlations amongst them. Its hermetic detection capability of correlated fragments promises to similarly allow for precise tomographic images of the quark-gluon landscape in nuclei, transcending from light few-body nuclei to the heaviest nuclei, and could uncover how the TMD and GPD landscape changes when gluons display an anticipated collective behavior at the higher energies
Electron–ion collider on the horizon
The National Academy of Sciences in the US finds a compelling scientific case for an advanced collider that would reveal how visible matter emerges from fundamental quarks and gluons