10 research outputs found
Theory of Phase Ordering Kinetics
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- 19/01/1995
- Field of study
The theory of phase ordering dynamics -- the growth of order through domain
coarsening when a system is quenched from the homogeneous phase into a
broken-symmetry phase -- is reviewed, with the emphasis on recent developments.
Interest will focus on the scaling regime that develops at long times after the
quench. How can one determine the growth laws that describe the time-dependence
of characteristic length scales, and what can be said about the form of the
associated scaling functions? Particular attention will be paid to systems
described by more complicated order parameters than the simple scalars usually
considered, e.g. vector and tensor fields. The latter are needed, for example,
to describe phase ordering in nematic liquid crystals, on which there have been
a number of recent experiments. The study of topological defects (domain walls,
vortices, strings, monopoles) provides a unifying framework for discussing
coarsening in these different systems.Comment: To appear in Advances in Physics. 85 pages, latex, no figures. For a
hard copy with figures, email [email protected]
Complete Genome Sequence of the N2-Fixing Broad Host Range Endophyte Klebsiella pneumoniae 342 and Virulence Predictions Verified in Mice
- Author
- A Burse
- A Czelleng
- A Krause
- A Krogh
- A Ruzin
- AE Osbourn
- AL Delcher
- AL Delcher
- AL Iniguez
- AL Iniguez
- AM George
- AM Osborn
- Anthony S. Durkin
- B Reiter
- Barbara A. Methé
- C d'Enfert
- C Struve
- C Struve
- C Zipfel
- Carsten Struve
- CJ Hueck
- CM Rojas
- CN Kästner
- CS Harwood
- D Bramhill
- D Eulberg
- D Ma
- D Zeidler
- DA Cuppels
- David S. Guttman
- DE Fouts
- DE Fouts
- Derrick E. Fouts
- DG Brown
- DG Thanassi
- E Masai
- E Saeland
- EA Campbell
- EH Weening
- Eric W. Triplett
- EW Myers
- F Jacob-Dubuisson
- G Felix
- GW Tyson
- H Erlendsdottir
- H Hvidberg
- H Priefert
- Heather Huot
- Heather L. Tyler
- Hoda Khouri
- HT Lau
- I Grissa
- I Raskin
- I Sobczak
- J Boch
- J Chaves
- JB Vicente
- JH Badger
- Jonathan H. Badger
- K Howe
- Karen A. Krogfelt
- KE Hammond-Kosack
- KE Nelson
- KJ Miller
- KS Bell
- L Gomez-Gomez
- L Guo
- L Hilden
- L Ielpi
- L Martinez
- LH Hansen
- LMBO Asad
- Luiz F. W. Roesch
- M Berlanga
- M Bott
- M Masi
- M Mikulasova
- M Oethinger
- M Pop
- M Rosenblueth
- M Sevilla
- M Sevilla
- MA Molina
- MJ Mahan
- MK Chelius
- MK Chelius
- ML Marco
- ML Marco
- ML Rabinovich
- MS Lawlor
- N Baranova
- N Kobayashi
- P Domenico
- P Domenico
- P Landini
- PJ Riggs
- Q Ren
- Q Ren
- Q Ren
- Qinghu Ren
- QL An
- R Barrangou
- R Podschun
- R Tamayo
- RB Helling
- RC Edgar
- RD Fleischmann
- RH Doi
- Robert J. Dodson
- Robert T. DeBoy
- S Ando
- S Pukatzki
- Sagar Kothari
- Sean Daugherty
- SF Altschul
- SJ Park
- SP Cohen
- Susmita Shrivastava
- SV Vasilieva
- T Danhorn
- T Kanamori
- T Komatsu
- T Komatsu
- T Schneiders
- TA Oelschlaeger
- W Arnold
- W Gish
- W Ogawa
- WD Rupp
- XX Zhang
- Y Dong
- Y Nakabeppu
- Y Ueda
- Yasmin Mohamoud
- YC Lai
- YM Dong
- YM Dong
- YT Chen
- Publication venue
- Public Library of Science
- Publication date
- 01/07/2008
- Field of study
We report here the sequencing and analysis of the genome of the nitrogen-fixing endophyte, Klebsiella pneumoniae 342. Although K. pneumoniae 342 is a member of the enteric bacteria, it serves as a model for studies of endophytic, plant-bacterial associations due to its efficient colonization of plant tissues (including maize and wheat, two of the most important crops in the world), while maintaining a mutualistic relationship that encompasses supplying organic nitrogen to the host plant. Genomic analysis examined K. pneumoniae 342 for the presence of previously identified genes from other bacteria involved in colonization of, or growth in, plants. From this set, approximately one-third were identified in K. pneumoniae 342, suggesting additional factors most likely contribute to its endophytic lifestyle. Comparative genome analyses were used to provide new insights into this question. Results included the identification of metabolic pathways and other features devoted to processing plant-derived cellulosic and aromatic compounds, and a robust complement of transport genes (15.4%), one of the highest percentages in bacterial genomes sequenced. Although virulence and antibiotic resistance genes were predicted, experiments conducted using mouse models showed pathogenicity to be attenuated in this strain. Comparative genomic analyses with the presumed human pathogen K. pneumoniae MGH78578 revealed that MGH78578 apparently cannot fix nitrogen, and the distribution of genes essential to surface attachment, secretion, transport, and regulation and signaling varied between each genome, which may indicate critical divergences between the strains that influence their preferred host ranges and lifestyles (endophytic plant associations for K. pneumoniae 342 and presumably human pathogenesis for MGH78578). Little genome information is available concerning endophytic bacteria. The K. pneumoniae 342 genome will drive new research into this less-understood, but important category of bacterial-plant host relationships, which could ultimately enhance growth and nutrition of important agricultural crops and development of plant-derived products and biofuels
Diminishing benefits of urban living for children and adolescents’ growth and development
- Author
- Abarca-Gomez L.
- Abdeen Z. A.
- Abdrakhmanova S.
- Abdul Rahim H. F.
- Abdurrahmonova Z.
- Abril G. L.
- Abu-Rmeileh N. M.
- Acosta-Cazares B.
- Adam I.
- Adamczyk M.
- Adams R. J.
- Adu-Afarwuah S.
- Aekplakorn W.
- Afsana K.
- Afzal S.
- Agbor V. N.
- Agdeppa I. A.
- Aghazadeh-Attari J.
- Aguenaou H.
- Aguilar-Salinas C. A.
- Agyemang C.
- Ahmad M. H.
- Ahmad N. A.
- Ahmadi A.
- Ahmadi N.
- Ahmadi N.
- Ahmed I.
- Ahmed S. H.
- Ahrens W.
- Aitmurzaeva G.
- Ajlouni K.
- Al Hourani H. M.
- Al Qaoud N. M.
- Al-Hazzaa H. M.
- Al-Lahou B.
- Al-Raddadi R.
- Alarouj M.
- AlBuhairan F.
- AlDhukair S.
- Aldwairji M. A.
- Alexius S.
- Ali M. M.
- Alkandari A.
- Alkerwi A.
- Alkhatib B. M.
- Allin K.
- Alvarez-Pedrerol M.
- Aly E.
- Amarapurkar D. N.
- Amoah J.
- Amougou N.
- Amouyel P.
- Andersen L. B.
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- Androutsos O.
- Angquist L.
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- Anufrieva E.
- Aounallah-Skhiri H.
- Araujo J.
- Ariansen I.
- Aris T.
- Arku R. E.
- Arlappa N.
- Aryal K. K.
- Aseffa N.
- Aspelund T.
- Assah F. K.
- Assembekov B.
- Assuncao M. C. F.
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- Auvinen J.
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- Publication venue
- Publication date
- 01/01/2023
- Field of study
Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified
Recommended from our members
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Aarestrup J
- Abarca-Gomez L
- Abbasi-Kangevari M
- Abdeen ZA
- Abdrakhmanova S
- Abdurrahmonova Z
- Abril GL
- Abu-Rmeileh NM
- Acosta-Cazares B
- Adam I
- Adamczyk M
- Adams RJ
- Adu-Afarwuah S
- Aekplakorn W
- Afsana K
- Afzal S
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- Pecin I
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- Quang NN
- Quintana HK
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- Radisauskas R
- Rahim HFA
- Rahim NCA
- Rahimikazerooni S
- Rahman M
- Rahman M
- Raitakari O
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- Rajabov T
- Rakhmatulloev S
- Rakovac I
- Ramachandran A
- Ramadan OPC
- Ramires VV
- Ramirez-Zea M
- Ramke J
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- Ramos R
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- Rampal S
- Ramsay SE
- Rangelova LS
- Rao KM
- Rao SR
- Rarra V
- Rascon-Pacheco RA
- Rashidi M-M
- Rayner AW
- Rech CR
- Redon J
- Reganit PFM
- Regecova V
- Renner JDP
- Repasy JA
- Reuter CP
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- Reynolds A
- Rezaei N
- Rezaianzadeh A
- Rho Y
- Ribas-Barba L
- Ribeiro R
- Riboli E
- Rigo F
- Rigotti A
- Riley LM
- Rinaldo N
- Ripolles MPD
- Riserus U
- Rito AI
- Ritti-Dias RM
- Rivera JA
- Roa RG
- Robinson L
- Roccaldo R
- Rodrigues D
- Rodriguez AY
- Rodriguez IS
- Rodriguez-Artalejo F
- Rodriguez-Artalejo F
- Rodriguez-Martinez A
- Rodriguez-Perez MDC
- Rodriguez-Villamizar LA
- Roggenbuck U
- Rohloff P
- Rohner F
- Rojas-Martinez R
- Rojroongwasinkul N
- Rolandi GEB
- Romaguera D
- Romeo EL
- Rosario AS
- Rosario RV
- Rosengren A
- Rouse I
- Rouzier V
- Roy JGR
- Ruano MH
- Rubinstein A
- Ruhli FJ
- Ruidavets J-B
- Ruiz-Betancourt BS
- Ruiz-Castell M
- Rusakova IA
- Rusek W
- Russo P
- Rust P
- Rutkowski M
- Saamel M
- Saar CG
- Sabanayagam C
- Sabbaghi H
- Sacchini E
- Sachdev HS
- Sadjadi A
- Safarpour AR
- Safi S
- Safiri S
- Saghi MH
- Saidi O
- Saieva C
- Sakata S
- Saki N
- Salaj S
- Salanave B
- Salhanova A
- Salmeron D
- Salomaa V
- Salonen JT
- Salvetti M
- Samoutian M
- Sanchez-Abanto J
- Sandjaja
- Sans S
- Sant'Angelo VF
- Santa-Marina L
- Santacruz E
- Santos DA
- Santos IS
- Santos LC
- Santos MP
- Santos O
- Santos R
- Santos TR
- Saramies JL
- Sardinha LB
- Sarrafzadegan N
- Sathish T
- Saum K-U
- Savin S
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- Savy M
- Sawada N
- Sbaraini M
- Scazufca M
- Schaan BD
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- Schienkiewitz A
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- Schmidt CO
- Schmidt IM
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- Schramm S
- Schramm S
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- Schultsz C
- Schultz G
- Schulze MB
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- Senbanjo IO
- Sepanlou SG
- Sequera G
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- Servais J
- Sevcikova L
- Sewpaul R
- Shalnova S
- Shamah-Levy T
- Shamshirgaran SM
- Shanthirani CS
- Sharafkhah M
- Sharma SK
- Sharman A
- Shaw JE
- Shayanrad A
- Shayesteh AA
- Shengelia L
- Shi Z
- Shibuya K
- Shimizu-Furusawa H
- Shimony T
- Shiri R
- Shrestha N
- Si-Ramlee K
- Siani A
- Siantar R
- Sibai AM
- Sidossis LS
- Silitrari N
- Silva AM
- Silva CRDM
- Silva DAS
- Silva KS
- Sim X
- Simina IJ
- Simon M
- Simone MK
- Simons J
- Simons LA
- Singleton RK
- Sjoberg A
- Sjostrom M
- Skoblina EV
- Skoblina NA
- Slazhnyova T
- Slowikowska-Hilczer J
- Slusarczyk P
- Smeeth L
- So H-K
- Soares FC
- Sobek G
- Sobngwi E
- Sodemann M
- Soderberg S
- Soekatri MYE
- Soemantri A
- Sofat R
- Solano MG
- Solfrizzi V
- Solovieva YV
- Somi MH
- Sonestedt E
- Song Y
- Soofi S
- Sorensen TIA
- Sorgjerd EP
- Soric M
- Soric M
- Soto-Rojas VE
- Soumare A
- Sousa-Poza A
- Sovic S
- Sparboe-Nilsen B
- Sparrenberger K
- Spencer PR
- Spinelli A
- Spiroski I
- Staessen JA
- Stamm H
- Stang A
- Starc G
- Staub K
- Stavreski B
- Steene-Johannessen J
- Stehle P
- Stein AD
- Steinsbekk S
- Stergiou GS
- Stessman J
- Stevanovic R
- Stevens GA
- Stieber J
- Stockl D
- Stokwiszewski J
- Stoyanova E
- Stratton G
- Stronks K
- Strufaldi MW
- Sturua L
- Suarez-Medina R
- Suarez-Ortegon MF
- Suebsamran P
- Sugiyama M
- Suka M
- Sulo G
- Sun C-A
- Sun L
- Sund M
- Sundstrom J
- Sung Y-T
- Sunyer J
- Suriyawongpaisal P
- Sweis NWG
- Swinburn BA
- Sy RG
- Sylva RC
- Szponar L
- Tabone L
- Tai ES
- Takuro F
- Tambalis KD
- Tammesoo M-L
- Tamosiunas A
- Tan EJ
- Tang X
- Tanrygulyyeva M
- Tanser F
- Tao Y
- Tarawneh MR
- Tarp J
- Tarqui-Mamani CB
- Taylor A
- Taylor J
- Tchibindat F
- Tebar WR
- Tell GS
- Tello T
- Tessema M
- Tham YC
- Thankappan KR
- Theobald H
- Theodoridis X
- Thi T-HT
- Thomas N
- Thorand B
- Thrift AG
- Ticha L
- Timmermans EJ
- Tjandrarini DH
- Tjonneland A
- Tolonen HK
- Tolstrup JS
- Tomaszewski M
- Topbas M
- Topor-Madry R
- Torheim LE
- Tornaritis MJ
- Torrent M
- Torres-Collado L
- Toselli S
- Touloumi G
- Traissac P
- Tran QB
- Tremblay MS
- Triantafyllou A
- Trichopoulos D
- Trichopoulou A
- Trinh OTH
- Trivedi A
- Tshepo L
- Tsigga M
- Tsintavis P
- Tsugane S
- Tuitele J
- Tuliakova AM
- Tulloch-Reid MK
- Tullu F
- Tuomainen T-P
- Tuomilehto J
- Turley M
- Turley ML
- Twig G
- Tynelius P
- Tzala E
- Tzotzas T
- Tzourio C
- Udoji N
- Ueda P
- Ugel E
- Ukoli FAM
- Ulmer H
- Unal B
- Usupova Z
- Uusitalo HMT
- Uysal N
- Vaitkeviciute J
- Valdivia G
- Vale S
- Valvi D
- van Dam RM
- van den Born B-J
- Van der Heyden J
- van der Schouw YT
- Van Herck K
- Van Lippevelde W
- Van Minh H
- Van Schoor NM
- van Valkengoed IGM
- Vanderschueren D
- Vanuzzo D
- Varbo A
- Varela-Moreiras G
- Vargas LN
- Varona-Perez P
- Vasan SK
- Vasques DG
- Vatasescu R
- Vega T
- Veidebaum T
- Velasquez-Melendez G
- Velde ST
- Velika B
- Verloigne M
- Veronesi G
- Verschuren WMM
- Victora CG
- Viegi G
- Viet L
- Vik FN
- Vilar M
- Villalpando S
- Vioque J
- Viriyautsahakul N
- Virtanen JK
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- Viswanathan B
- Vladulescu M
- Vlasoff T
- Vocanec D
- Vollenweider P
- Volzke H
- Vourli G
- Voutilainen A
- Vrijheid M
- Vrijkotte TGM
- Vrkic TZ
- Vuletic S
- Wade AN
- Waldhor T
- Walton J
- Wambiya EOA
- Wanderley Junior RDS
- Wang C
- Wang H
- Wang L
- Wang L
- Wang M-D
- Wang N
- Wang Q
- Wang X
- Wang Y-W
- Wang YX
- Wannamethee SG
- Wareham N
- Wartha O
- Weber A
- Webster-Kerr K
- Webster-Kerr K
- Wedderkopp N
- Weghuber D
- Wei W
- Weres A
- Werner B
- Westbury LD
- Whincup PH
- Wichstrom L
- Wickramasinghe K
- Widhalm K
- Widyahening IS
- Wiecek A
- Wild PS
- Wilks RJ
- Willeit J
- Willeit P
- Williams J
- Wilsgaard T
- Wirth JP
- Wojtyniak B
- Woldeyohannes M
- Wolf K
- Wong A
- Wong EB
- Wong JE
- Wong NI
- Wong TY
- Wong-McClure RA
- Woo J
- Woodward M
- Wu FC
- Wu H-Y
- Wu J
- Wu LJ
- Wu S
- Wyszynska J
- Xu H
- Xu L
- Yaacob NA
- Yamborisut U
- Yan L
- Yan W
- Yang L
- Yang X
- Yang Y
- Yardim N
- Yasuharu T
- Yiallouros PK
- Yngve A
- Yoosefi M
- Yoshihara A
- Yotov Y
- You QS
- You S-L
- Younger-Coleman NO
- Yu Y
- Yu Y-L
- Yusof SM
- Yusoff AF
- Yusoff MFM
- Zaccagni L
- Zafiropulos V
- Zainuddin AA
- Zakavi SR
- Zamani F
- Zambon S
- Zampelas A
- Zamrazilova H
- Zapata ME
- Zargar AH
- Zaw KK
- Zayed AA
- Zdrojewski T
- Zeglen M
- Zejglicova K
- Zeng Y
- Zentai A
- Zhang B
- Zhang L
- Zhang Z-Y
- Zhao D
- Zhao M-H
- Zhao W
- Zhecheva YV
- Zhen S
- Zheng W
- Zheng Y
- Zholdin B
- Zhou B
- Zhou M
- Zhu D
- Zimmet P
- Zins M
- Zitt E
- Zocalo Y
- Zoghlami N
- Zuziak M
- Publication venue
- Elsevier
- Publication date
- 14/03/2024
- Field of study
Background
Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods
We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median).
Findings
From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness.
Interpretation
The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity.
Funding
UK Medical Research Council, UK Research and Innovation (Research England), UK Research and Innovation (Innovate UK), and European Union
The south atlantic whale sanctuary (saws) and sanctuary review criteria
- Author
- Publication venue
- Publication date
- 01/01/2004
- Field of study
Concerns Regarding Scientific Permits
- Author
- A. Read
- B. Taylor
- B. Wilson
- C. Clark
- C. Fortuna
- C. Parsons
- C. Perry
- C. S. Baker
- D. Senn
- D. thiele
- E. Rogan
- F. Borsani
- FOSSI MARIA CRISTINA
- G. Lauriano
- H. Oosthuizen
- J. Palazzo
- K. Groch
- K. H. Kock
- K. Martien
- L. Kell
- L. Rojas
- l. Sadler
- M. Iniguez
- M. Krahn
- M. Simmonds
- M. Stachowitsch
- N. Gales
- P. Berggren
- P. Clapham
- P. Reijnders
- P. Wade
- R. Brownell
- R. Leaper
- R. Pinto de Lima
- S. Childerhouse
- S. Manzanilla
- S. Reilly
- T. Lyrholm
- V. Ridoux
- W. Perrin
- Publication venue
- Publication date
- 01/01/2004
- Field of study
Genome-wide simple sequence repeats (SSR) markers discovered from whole-genome sequence comparisons of multiple spinach accessions
- Author
- A Edwards
- A Ribera
- A Ribera
- A Shi
- A Untergasser
- AO Uncu
- B Kalyana Babu
- BM Irish
- C Feng
- C Feng
- C Feng
- C Xu
- CH Parada-Rojas
- DA Earl
- F Mercati
- FL Iniguez-Luy
- G Bhattarai
- G Bhattarai
- G Bhattarai
- G Cai
- G Cao
- G Cipriani
- G Evanno
- G Highnam
- H Li
- H She
- H Zhu
- J Cheng
- J Engelbrecht
- J Klein
- J Sneep
- J Xu
- J Zhao
- JAG da Silva
- JE Zalapa
- JK Pritchard
- JZK Khattak
- K Fletcher
- K Kuwahara
- K Liu
- K Riangwong
- K Tamura
- LR Howard
- M Gymrek
- M Sato
- M Schuelke
- MD Cao
- MK Biswas
- OK Kamneva
- PJ Bradbury
- PJ Hiremath
- R Peakall
- R van Treuren
- RGJ Hodel
- RK Kalia
- S Arora
- S Gyawali
- S Kumar
- S Srivastava
- SB Andersen
- SF Li
- T Sugita
- T Willems
- TE Morelock
- VE Rubatzky
- X Wang
- Y Onda
- Ş Göl
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Appropriateness of antiplatelet therapy for primary and secondary cardio- and cerebrovascular prevention in acutely hospitalized older people
- Author
- (Afeltra A
- (Agosti P
- (Alcidi R
- (Alfonso L
- (Amabile A
- (Amoruso E
- (Anastasio L
- (Annoni G
- (Arcopinto M
- (Ardoino I
- (Arno R
- (Arraigosa Antonio Aa
- (Arturi F
- (Baena Susana Sb
- (Baldassarre S
- (Ballestrero A
- (Barbagallo M
- (Bartone M
- (Bassi Sl
- (Battaglia R
- (Beccati V
- (Becerra Concepcion Gb
- (Behamonte Esther Dcb
- (Bellelli G
- (Beneduce V
- (Bernardi M
- (Berra S
- (Berria M
- (Bertolotti M
- (Bertozzi I
- (Bettiol A
- (Bianchi Gb
- (Bianconi V
- (Biolo G
- (Biondi L
- (Blanco J
- (Bleve Ma
- (Boari B
- (Bobbio E
- (Bogoni G
- (Bonfanti A
- (Bonini G
- (Borghi C
- (Bosco J
- (Bracco C
- (Bran David Rb
- (Brucato A
- (Brunori M
- (Bussolino C
- (Busti F
- (Calipari D
- (Campiotti L
- (Cantero Alberto Rc
- (Capecchi Pl
- (Capeci W
- (Cappelli S
- (Cappellini Md
- (Carbone M
- (Carulli L
- (Caserza L
- (Castellino P
- (Castiglioni L
- (Catena C
- (Caterina C
- (Cattaneo F
- (Cavallaro F
- (Ceriani G
- (Cervellera Alfonso Gcc
- (Cesari M
- (Cespiati A
- (Chiuch M
- (Cilli M
- (Cipollone F
- (Cittadini A
- (Clerici M
- (Cocita F
- (Colangelo L
- (Colombo G
- (Colussi G
- (Comitangelo A
- (Conti F
- (Corrao S
- (Corsi M
- (Cosi E
- (Cuadros Raquel Pc
- (D'Aurizio G
- (Dal Col A
- (Dallegri F
- (Damanti S
- (Damiani G
- (Dassi S
- (De Amicis Mm
- (De Giorgi A
- (De Giorgio R
- (De Luca G
- (De Vincenzo Gm
- (del Vecchio S
- (Delitala A
- (Delitala G
- (Dell'Unto C
- (Di Blanca D
- (Di Gennaro C
- (Di Pino A
- (Di Sabatino A
- (Di Stefano V
- (Dominguez L
- (Dominioni Cc
- (Dondi G
- (Duque Nieves Rd
- (Emmi G
- (Fabbian F
- (Fabbri E
- (Fabio G
- (Fabris F
- (Falanga L
- (Falcetta A
- (Fargion S
- (Favale E
- (Fenoglio L
- (Ferrandina C
- (Ferrando F
- (Ferrari B
- (FIlice M
- (Fogliati M
- (Folli C
- (Fracanzani Al
- (Fragapani S
- (Francesc F
- (Franchi C
- (Gabrielli A
- (Galanti G
- (Galassi M
- (Gallego Marta Ag
- (Gallo P
- (Garcia Sara Cg
- (Gasbarrone L
- (Gasparini F
- (Gaudenzi P
- (Gennaro A
- (Gentilucci Uv
- (Ghelfi D
- (Ghidoni S
- (Ghio R
- (Giaquinto S
- (Gino M
- (Gioffre V
- (Girelli D
- (Girino M
- (Gomez Hernandez Mg
- (Gonzalez-Cobos Cristina Lgc
- (Grassi Y
- (Graziella B
- (Grignani G
- (Grossi A
- (Gruden G
- (Guadagni M
- (Guagnano Mt
- (Guasti L
- (Guerrero Montserrat Gg
- (Ianniello E
- (Jose Manuel Mj
- (Labbadia G
- (Lancellotti G
- (Landolfi R
- (Lara T
- (Lazzari I
- (Lenti Mv
- (Leonardi R
- (Libbra Mv
- (Liberale L
- (Liberato Nl
- (Llorente Blanca Pl
- (Loparco F
- (Lupattelli G
- (Magalotti D
- (Maio R
- (Maira D
- (Mancarella M
- (Mancuso G
- (Manfredini R
- (Manglano Jesus Dm
- (Mannarino E
- (Mannucci Pm
- (Manzoni F
- (Marchi G
- (Marengoni A
- (Maresca A
- (Marigliano B
- (Marra A
- (Marra Am
- (Martinelli S
- (Martinez Marta Pm
- (Martino Gp
- (Mascherini G
- (Mattioli M
- (Mazzola P
- (Mete F
- (Miceli E
- (Miguel Angel Brm
- (Minisola S
- (Mirijello A
- (Modeo Me
- (Molfino A
- (Molinero Alberto Mm
- (Montalto M
- (Montrucchio G
- (Monzani V
- (Moreo G
- (Moyano Antonio Fm
- (Mularo S
- (Murialdo G
- (Muscaritoli M
- (Mussi C
- (Nasso F
- (Natoli G
- (Nava Mc
- (Nobili A
- (Nobili G
- (Nuti R
- (Oberti G
- (Olid Beatriz Go
- (Omenetto E
- (Ottolini Bb
- (Ottonello L
- (Paciullo F
- (Palasciano G
- (Palazzuoli A
- (Pallini G
- (Paolisso G
- (Pasina L
- (Pasini Fl
- (Pasquale M
- (Peasso P
- (Pelaez Vanessa Lp
- (Pellegrini E
- (Perri L
- (Perticone F
- (Perticone M
- (Pes C
- (Petitti P
- (Petri C
- (Petrillo E
- (Pettinari P
- (Peyvandi F
- (Peyvandi F
- (Picardi A
- (Piccinelli V
- (Pignataro S
- (Pina G
- (Pipita Me
- (Piro S
- (Pisati M
- (Plances L
- (Poletto C
- (Pontremoli R
- (Poyato Borrego Mp
- (Prandini T
- (Prego Monica Rp
- (Prisco D
- (Prolo S
- (Pulixi Ea
- (Puras Maria Sp
- (Purrello F
- (Rabuini Mv
- (Raspanti M
- (Requejo Pedro Ar
- (Rizzo Mr
- (Rojas Florencia Pr
- (Romanelli G
- (Romero M
- (Rossi I
- (Rossi Pd
- (Rossio R
- (Rossio R
- (Rozzini R
- (Rubino M
- (Ruggeri E
- (Ruvio M
- (Sabba C
- (Saez L
- (Sajeva Mr
- (Salam K
- (Salerno F
- (Salmi R
- (Salvi A
- (Salzano A
- (Santi L
- (Saracco V
- (Savojardo V
- (Scaramellini N
- (Scarinzi P
- (Scattolin G
- (Schilardi A
- (Secchi Mb
- (Sechi L
- (Seghezzi S
- (Serra Mg
- (Sesti G
- (Sigon G
- (Silvestri E
- (Sirico D
- (Sofia L
- (Soldati M
- (Spazzini E
- (Squizzato A
- (Stanghellini V
- (Stefani L
- (Strocchi E
- (Suarez Lucia As
- (Succurro E
- (Suppressa P
- (Szabo H
- (Tassone B
- (Tello Esperanza Bt
- (Tiraboschi S
- (Tiseo R
- (Tognin T
- (Turrin M
- (Valenti R
- (Valeriani E
- (Vanoli M
- (Vazquez Iria Vi
- (Veleiro Ignacio Nv
- (Vella Fs
- (Victoria Vgm
- (Vigorito C
- (Violi F
- (Viros Xavier Cv
- (Volpini A
- (Zaccari M
- (Zaccari M
- (Zaccherini G
- (Zanetti M
- (Zanoli L
- (Zazzetta S
- (Zoli M
- (Zuccala G
- (Zucchelli A
- )( 41 ) Anna L.
- )( 84 ) Villalba Garcia M.
- ) 45
- ) 45
- ) 56
- ) 56
- ) 56
- ) 56
- ) 56
- ) 56
- ) Abad)( 80
- ) Albarracin)( 90
- ) Alberto Maria)( 68
- ) Alberto)( 10
- ) Alberto)( 28
- ) Alberto)( 70
- ) Alessandra)( 28
- ) Alessandra)( 30
- ) Alessandro)( 25
- ) Alessio)( 20
- ) Alessio)( 26
- ) Alessio)( 39
- ) Alfio)( 65
- ) Alfredo)( 36
- ) Alvela)( 92
- ) Andrea)( 28
- ) Andrea)( 39
- ) Andrea)( 40
- ) Andrea)( 60
- ) Andrea)( 68
- ) Anna)( 62
- ) Annalisa)( 35
- ) Annalisa)( 41
- ) Antonella)( 64
- ) Antonino)( 49
- ) Antonio)( 19
- ) Antonio)( 29
- ) Antonio)( 34
- ) Antonio)( 54
- ) Antonio)( 68
- ) Armando)( 61
- ) Arroyo)( 86
- ) Barbara Brignolo)( 18
- ) Barbara)( 42
- ) Baron Ramos)( 90
- ) Bejarano)( 82
- ) Benedetta)( 36
- ) Benedetta)( 64
- ) Bruno)( 31
- ) Bruno)( 72
- ) Camillo)( 50
- ) Carla)( 16
- ) Carlo)( 39
- ) Carlo)( 66
- ) Carlo)( 68
- ) Carrascosa)( 88
- ) Cesare)( 51
- ) Chiara)( 25
- ) Chiara)( 29
- ) Chiara)( 57
- ) Christian)( 40
- ) Christian)( 43
- ) Claudio)( 38
- ) Corbella)( 81
- ) Costanza Caccia)( 19
- ) Cristian)( 73
- ) Cristina)( 77
- ) Daniela)( 24
- ) Davide)( 21
- ) Del Corral)( 82
- ) Diez)( 82
- ) Diletta)( 17
- ) Domenico)( 11
- ) Domenico)( 68
- ) Donatella)( 14
- ) Edoardo)( 51
- ) Elena)( 31
- ) Elena)( 50
- ) Elisa)( 14
- ) Elisa)( 57
- ) Elisabetta)( 35
- ) Elisabetta)( 35
- ) Emanuela)( 19
- ) Emanuele)( 23
- ) Emanuele)( 39
- ) Emanuele)( 68
- ) Enrico)( 26
- ) Enrico)( 38
- ) Eugenia)( 38
- ) Eugenio)( 59
- ) Fabiana)( 11
- ) Fabio)( 36
- ) Fabio)( 70
- ) Fabrizio)( 35
- ) Federica)( 13
- ) Federica)( 18
- ) Federico)( 20
- ) Fernandez)( 87
- ) Flora)( 42
- ) Floriana)( 12
- ) Formiga)( 81
- ) Francesca)( 28
- ) Francesca)( 39
- ) Francesca)( 67
- ) Francesca)( 69
- ) Francesco Saverio)( 39
- ) Francesco)( 23
- ) Francesco)( 49
- ) Francesco)( 53
- ) Francesco)( 58
- ) Francesco)( 75
- ) Franco Laghi)( 15
- ) Franco)( 31
- ) Franco)( 46
- ) Gabriele)( 73
- ) Gabriella)( 27
- ) Gabriella)( 72
- ) Garcia)( 88
- ) Gerardo)( 24
- ) Giacomo)( 11
- ) Giacomo)( 17
- ) Giampaolo)( 60
- ) Giancarlo)( 63
- ) Gianluca)( 77
- ) Giordano)( 41
- ) Giorgio)( 30
- ) Giorgio)( 31
- ) Giorgio)( 73
- ) Giovanna)( 17
- ) Giovanna)( 41
- ) Giovanni Battista)( 48
- ) Giovanni Michele)( 39
- ) Giovanni)( 20
- ) Giulia)( 18
- ) Giulia)( 20
- ) Giulia)( 35
- ) Giulia)( 42
- ) Giulia)( 57
- ) Giulia)( 57
- ) Giuliana)( 43
- ) Giuseppe Pio)( 61
- ) Giuseppe)( 13
- ) Giuseppe)( 16
- ) Giuseppe)( 25
- ) Giuseppe)( 27
- ) Giuseppe)( 29
- ) Giuseppe)( 30
- ) Giuseppe)( 37
- ) Giuseppe)( 51
- ) Giuseppe)( 76
- ) Gloria)( 69
- ) Godoy)( 90
- ) Gonzalez)( 87
- ) Gonzalez-Cruz)( 89
- ) Guido)( 69
- ) Hajnalka)( 30
- ) Ilaria)( 14
- ) Ilaria)( 23
- ) Iniguez)( 93
- ) Irene)( 35
- ) Juan)( 85
- ) Julien)( 65
- ) Kassem)( 46
- ) Lara)( 46
- ) Laura)( 33
- ) Laura)( 73
- ) Leonardo)( 77
- ) Lidia)( 12
- ) Ligia)( 12
- ) Lina)( 50
- ) Lopez)( 80
- ) Lopez)( 84
- ) Lopez)( 85
- ) Lopez)( 93
- ) Lorenzo)( 61
- ) Luca)( 46
- ) Luca)( 65
- ) Lucia)( 22
- ) Lucia)( 57
- ) Luciano)( 46
- ) Luciano)( 63
- ) Ludovica)( 53
- ) Luigi)( 22
- ) Luigi)( 40
- ) Machin)( 91
- ) Manuel)( 83
- ) Manuel)( 87
- ) Marco Vincenzo)( 19
- ) Marco)( 14
- ) Marco)( 57
- ) Marco)( 58
- ) Margherita Migone)( 17
- ) Margherita)( 74
- ) Maria Antonietta)( 32
- ) Maria Beatrice)( 21
- ) Maria Cristina)( 71
- ) Maria Domenica)( 17
- ) Maria Elena)( 64
- ) Maria Ester)( 16
- ) Maria Grazia)( 32
- ) Maria Rosaria)( 33
- ) Maria Rosaria)( 37
- ) Maria Teresa)( 23
- ) Maria Victoria)( 35
- ) Maria Vittoria)( 57
- ) Maria)( 22
- ) Maria)( 25
- ) Maria)( 58
- ) Maria)( 75
- ) Mariangela)( 31
- ) Mario)( 12
- ) Mario)( 38
- ) Marisa)( 66
- ) Marta)( 17
- ) Marta)( 18
- ) Martina)( 10
- ) Martina)( 19
- ) Massimo)( 13
- ) Massimo)( 54
- ) Massimo)( 61
- ) Matteo)( 18
- ) Matteo)( 57
- ) Mattia)( 14
- ) Maurizio)( 26
- ) Maurizio)( 30
- ) Mauro)( 76
- ) Mercedes)( 87
- ) Michele)( 68
- ) Mirella)( 63
- ) Miriam)( 67
- ) Mose)( 24
- ) Muela)( 79
- ) Natalia)( 17
- ) Nicola Lucio)( 47
- ) Novo)( 92
- ) Pacheco)( 88
- ) Paolo Dionigi)( 18
- ) Paolo)( 29
- ) Paolo)( 30
- ) Paolo)( 35
- ) Paolo)( 51
- ) Paolo)( 51
- ) Pasquale)( 42
- ) Patrizia)( 39
- ) Peinado)( 89
- ) Perez)( 88
- ) Pier Leopoldo)( 15
- ) Piergiorgio)( 52
- ) Pietro)( 61
- ) Pietro)( 65
- ) Pinilla)( 84
- ) Raffaele)( 54
- ) Raffaele)( 58
- ) Raffaella)( 14
- ) Raffaella)( 42
- ) Raffaella)( 52
- ) Ramirez)( 78
- ) Ranuccio)( 10
- ) Renzo)( 50
- ) Riccardo)( 62
- ) Rios)( 94
- ) Roberto)( 10
- ) Roberto)( 20
- ) Roberto)( 36
- ) Roberto)( 36
- ) Roberto)( 60
- ) Rosa)( 58
- ) Ruana)( 36
- ) Rubal)( 93
- ) Ruiz)( 90
- ) Sabrina)( 48
- ) Salvatore)( 13
- ) Salvatore)( 13
- ) Salvatore)( 49
- ) Salvatore)( 63
- ) Salvatore)( 72
- ) Samuele)( 65
- ) Sanz)( 86
- ) Sara)( 30
- ) Sara)( 59
- ) Sarah)( 18
- ) Sergio)( 71
- ) Sergio)( 76
- ) Sevil)( 82
- ) Silvia)( 10
- ) Silvia)( 34
- ) Silvia)( 41
- ) Silvia)( 41
- ) Silvia)( 69
- ) Simonetta)( 71
- ) Sonia)( 17
- ) Stefano)( 72
- ) Tamargo)( 80
- ) Tancredi)( 35
- ) Tiziana)( 47
- ) Umberto Vespasiani)( 29
- ) Valentina)( 20
- ) Valeria)( 17
- ) Valeria)( 43
- ) Valeria)( 74
- ) Valter)( 43
- ) Valter)( 66
- ) Vincenza)( 12
- ) Vincenza)( 75
- ) Vincenzo)( 59
- ) William)( 61
- ) Yasmine)( 57
- 1 ) Ilaria)(
- 2 ) Flora)(
- 2 ) Raffaella)(
- 3 ) Alessandro)(
- 3 ) Carlotta)(
- 3 ) Donnatella)(
- 3 ) Luca)(
- 4 ) Pier Mannuccio)(
- 44 Francesco)(
- 44 Giada)(
- 5 ) Alessandra)(
- 5 ) Cenci)(
- 5 ) Domenico)(
- 5 ) Elena)(
- 5 ) Giacomo)(
- 55 Alessandra)(
- 55 Alessandro)(
- 55 Andrea)(
- 55 Leonardo)(
- 55 Luana)(
- 55 Luigina)(
- 6 ) Gianni)(
- 6 ) Martina)(
- 6 ) Massimiliano)(
- 6 ) Michela)(
- 6 ) Michele)(
- 7 ) Edoardo Alessandro)(
- 7 ) Giulia)(
- 7 ) Massimo)(
- 8 ) Giacomo)(
- 8 ) Luca)(
- 8 ) Mauro)(
- 8 ) Silvia Li)(
- 9 ) Elmo)(
- 9 ) Francesco)(
- 9 ) Graziana)(
- 9 ) Riccardo)(
- 9 ) Vanessa)(
- Afeltra
- Agosti
- Alberto
- Alberto
- Alcidi
- Alfonso
- Alfonso
- Amabile
- Amicis De
- Amoruso
- Anastasio
- Angel
- Annoni
- Antonio
- Antonio
- Arcopinto
- Arno
- Arturi
- Baldassarre
- Ballestrero
- Barbagallo
- Bartone
- Bassi
- Battaglia
- Beatriz
- Beccati
- Bellelli
- Beneduce
- Bernardi
- Berra
- Berria
- Bertolotti
- Bertozzi
- Bettiol
- Bianchi
- Bianconi
- Biolo
- Biondi
- Blanca
- Blanca Di
- Blanco
- Bleve
- Boari
- Bobbio
- Bogoni
- Bonfanti
- Bonini
- Borghi
- Borrego
- Bosco
- Bracco
- Brucato
- Brunori
- Bussolino
- Busti
- By:ardoino
- Calipari
- Campiotti
- Capecchi
- Capeci
- Cappelli
- Cappellini
- Carbone
- Carulli
- Caserza
- Castellino
- Castiglioni
- Catena
- Caterina
- Cattaneo
- Cavallaro
- Ceriani
- Cesari
- Cespiati
- Chiuch
- Cilli
- Cipollone
- Cittadini
- Clerici
- Cocita
- Col Dal
- Colangelo
- Colombo
- Colussi
- Comitangelo
- Concepcion
- Conti
- Corrao
- Corsi
- Cosi
- Cristina
- D'Aurizio
- Dallegri
- Damanti
- Damiani
- Dassi
- David
- Delitala
- Delitala
- Dell'Unto
- Dominguez
- Dominioni
- Dondi
- Emmi
- Esperanza
- Esther
- Fabbian
- Fabbri
- Fabio
- Fabris
- Falanga
- Falcetta
- Fargion
- Favale
- Fenoglio
- Ferrandina
- Ferrando
- Ferrari
- Filice
- Florencia
- Fogliati
- Folli
- Fracanzani
- Fragapani
- Francesc
- Franchi
- Gabrielli
- Galanti
- Galassi
- Gallo
- Gasbarrone
- Gasparini
- Gaudenzi
- Gennaro
- Gennaro Di
- Gentilucci
- Ghelfi
- Ghidoni
- Ghio
- Giaquinto
- Gino
- Gioffre
- Giorgi De
- Giorgio De
- Girelli
- Girino
- Grassi
- Graziella
- Grignani
- Grossi
- Gruden
- Guadagni
- Guagnano
- Guasti
- Hernandez
- Ianniello
- Ignacio
- Iniguez
- Jesus
- Labbadia
- Lancellotti
- Landolfi
- Lara
- Lazzari
- Lenti
- Leonardi
- Libbra
- Liberale
- Liberato
- Loparco
- Luca De
- Lucia
- Lupattelli
- Magalotti
- Maio
- Maira
- Mancarella
- Mancuso
- Manfredini
- Mannarino
- Mannucci
- Manuel
- Manzoni
- Marchi
- Marengoni
- Maresca
- Maria
- Marigliano
- Marra
- Marra
- Marta
- Marta
- Martinelli
- Martino
- Mascherini
- Mattioli
- Mazzola
- Mete
- Miceli
- Minisola
- Mirijello
- Modeo
- Molfino
- Monica
- Montalto
- Montrucchio
- Montserrat
- Monzani
- Moreo
- Mularo
- Murialdo
- Muscaritoli
- Mussi
- Nasso
- Natoli
- Nava
- Nieves
- Nobili
- Nobili
- Nuti
- Oberti
- Omenetto
- Ottolini
- Ottonello
- Paciullo
- Palasciano
- Palazzuoli
- Pallini
- Paolisso
- Pasina
- Pasini
- Pasquale
- Peasso
- Pedro
- Pellegrini
- Perri
- Perticone
- Perticone
- Pes
- Petitti
- Petri
- Petrillo
- Pettinari
- Peyvandi
- Peyvandi
- Picardi
- Piccinelli
- Pignataro
- Pina
- Pino Di
- Pipita
- Piro
- Pisati
- Plances
- Poletto
- Pontremoli
- Prandini
- Prisco
- Prolo
- Pulixi
- Purrello
- Rabuini
- Raquel
- Raspanti
- Rizzo
- Romanelli
- Romero
- Rossi
- Rossi
- Rossio
- Rossio
- Rozzini
- Rubino
- Ruggeri
- Ruvio
- Sabatino Di
- Sabba
- Saez
- Sajeva
- Salam
- Salerno
- Salmi
- Salvi
- Salzano
- Santi
- Sara
- Saracco
- Savojardo
- Scaramellini
- Scarinzi
- Scattolin
- Schilardi
- Secchi
- Sechi
- Seghezzi
- Serra
- Sesti
- Sigon
- Silvestri
- Sirico
- Sofia
- Soldati
- Spazzini
- Squizzato
- Stanghellini
- Stefani
- Stefano Di
- Strocchi
- Succurro
- Suppressa
- Susana
- Szabo
- Tassone
- Tiraboschi
- Tiseo
- Tognin
- Turrin
- Valenti
- Valeriani
- Vanessa
- Vanoli Michele)
- Vecchio Del
- Vella
- Victoria
- Vigorito
- Vincenzo De
- Violi
- Volpini
- Xavier
- Zaccari
- Zaccari
- Zaccherini
- Zanetti
- Zanoli
- Zazzetta
- Zoli
- Zuccala
- Zucchelli
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2017
- Field of study
Aims: Antiplatelet therapy is recommended for the secondary prevention of cardio- and cerebrovascular disease, but for primary prevention it is advised only in patients at very high risk. With this background, this study aims to assess the appropriateness of antiplatelet therapy in acutely hospitalized older people according to their risk profile. Methods: Data were obtained from the REPOSI register held in Italian and Spanish internal medicine and geriatric wards in 2012 and 2014. Hospitalized patients aged 6565 assessable at discharge were selected. Appropriateness of the antiplatelet therapy was evaluated according to their primary or secondary cardiovascular prevention profiles. Results: Of 2535 enrolled patients, 2199 were assessable at discharge. Overall 959 (43.6%, 95% CI 41.5\u201345.7) were prescribed an antiplatelet drug, aspirin being the most frequently chosen. Among patients prescribed for primary prevention, just over half were inappropriately prescribed (52.1%), being mainly overprescribed (155/209 patients, 74.2%). On the other hand, there was also a high rate of inappropriate underprescription in the context of secondary prevention (222/726 patients, 30.6%, 95% CI 27.3\u201334.0%). Conclusions: This study carried out in acutely hospitalized older people shows a high degree of inappropriate prescription among patients prescribed with antiplatelets for primary prevention, mainly due to overprescription. Further, a large proportion of patients who had had overt cardio- or cerebrovascular disease were underprescribed, in spite of the established benefits of antiplatelet drugs in the context of secondary prevention
Global urban environmental change drives adaptation in white clover
- Author
- Aguirre Windsor E
- Akinwole Philips O
- Alberti Marina
- Alvarez Jackie
- Anderson Jill T
- Anderson Joseph J
- Ando Yoshino
- Andrew Nigel R
- Angeoletto Fabio
- Anstett Daniel N
- Anstett Julia
- Aoki-Goncalves Felipe
- Arietta AZ Andis
- Arroyo Mary TK
- Austen Emily J
- Baena-Diaz Fernanda
- Barker Cory A
- Baylis Howard A
- Bazargani Mitra Mohammadi
- Beliz Julia M
- Benitez-Mora Alfonso
- Bickford David
- Biedebach Gabriela
- Blackburn Gwylim S
- Boehm Mannfred MA
- Bonser Stephen P
- Bonte Dries
- Bragger Jesse R
- Branquinho Cristina
- Brans Kristien I
- Bresciano Jorge C
- Brom Peta D
- Bucharova Anna
- Burt Briana
- Cahill James F
- Campbell Katelyn D
- Carlen Elizabeth J
- Carmona Diego
- Castellanos Maria Clara
- Centenaro Giada
- Chalen Izan
- Chaves Jaime A
- Chavez-Pesqueira Mariana
- Chen Xiao-Yong
- Chilton Angela M
- Chomiak Kristina M
- Cisneros-Heredia Diego F
- Cisse Ibrahim K
- Classen Aimee T
- Cohan Beata
- Comerford Mattheau S
- Corney Hannah
- Crawford Andrew J
- Crawford Kerri M
- Dahirel Maxime
- David Santiago
- De Haan Robert
- Deacon Nicholas J
- Dean Clare
- Del-Val Ek
- Deligiannis Eleftherios K
- Denney Derek
- Dettlaff Margarete A
- DiLeo Michelle F
- Ding Yuan-Yuan
- Dominguez-Lopez Moises E
- Dominoni Davide M
- Draud Savannah L
- Dyson Karen
- Ellers Jacintha
- Espinosa Carlos I
- Essi Liliana
- Falahati-Anbaran Mohsen
- Falcao Jessica CF
- Fargo Hayden T
- Fellowes Mark DE
- Fitzpatrick Connor R
- Fitzpatrick Raina M
- Flaherty Leah E
- Flood Padraic J
- Flores Maria F
- Fornoni Juan
- Foster Amy G
- Fradinger Camila Cordoba
- Frost Christopher J
- Fuentes Tracy L
- Fulkerson Justin R
- Gagnon Edeline
- Garbsch Frauke
- Garroway Colin J
- Gerstein Aleeza C
- Giasson Mischa M
- Girdler E Binney
- Gkelis Spyros
- Godsoe William
- Golemiec Anneke M
- Golemiec Mireille
- Gonzalez-Lagos Cesar
- Gorton Amanda J
- Gotanda Kiyoko M
- Granath Gustaf
- Greiner Stephan
- Griffiths Joanna S
- Grilo Filipa
- Gundel Pedro E
- Hamilton Benjamin
- Hardin Joyce M
- He Tianhua
- Heard Stephen B
- Henriques Andre F
- Hernandez-Poveda Melissa
- Hetherington-Rauth Molly C
- Hill Sarah J
- Hochuli Dieter F
- Hodgins Kathryn A
- Hood Glen R
- Hopkins Gareth R
- Hovanes Katherine A
- Howard Ava R
- Hubbard Sierra C
- Ibarra-Cerdena Carlos N
- Iniguez-Armijos Carlos
- Innes Simon G
- Jara-Arancio Paola
- Jarrett Benjamin JM
- Jeannot Manon
- Jimenez-Lobato Vania
- Johnson Mae
- Johnson Marc TJ
- Johnson Oscar
- Johnson Philip P
- Johnson Reagan
- Josephson Matthew P
- Jung Meen Chel
- Just Michael G
- Kahilainen Aapo
- Kailing Otto S
- Karinho-Betancourt Eunice
- Karousou Regina
- Kirn Lauren A
- Kirschbaum Anna
- Koch Sophie
- Laine Anna-Liisa
- LaMontagne Jalene M
- Lampei Christian
- Lara Carlos
- Larson Erica L
- Lazaro-Lobo Adrian
- Le Jennifer H
- Leandro Deleon S
- Lee Christopher
- Lei Yunting
- Leon Carolina A
- Levesque Danica C
- Liao Wan-Jin
- Ljubotina Megan
- Locke Hannah
- Lockett Martin T
- Longo Tiffany C
- Lundholm Jeremy T
- MacGillavry Thomas
- Mackin Christopher R
- Mahmoud Alex R
- Manju Isaac A
- Marien Janine
- Martinez D Nayeli
- Martinez-Bartolome Marina
- Meineke Emily K
- Mendoza-Arroyo Wendy
- Merritt Lila Elizabeth L
- Merritt Thomas JS
- Migiani Giuditta
- Miles Lindsay S
- Minor Emily S
- Mitchell Nora
- Moles Angela T
- Monk Julia D
- Moore Christopher M
- Morales-Morales Paula A
- Moyers Brook T
- Munim Samreen
- Munoz-Rojas Miriam
- Munshi-South Jason
- Murphy Shannon M
- Murua Maureen M
- Neila Melisa
- Ness Rob W
- Nikolaidis Ourania
- Njunji Iva
- Nosko Peter
- Nunez-Farfan Juan
- Ohgushi Takayuki
- Olsen Kenneth M
- Opedal Oystein H
- Ornelas Cristina
- Parachnowitsch Amy L
- Paratore Aaron S
- Parody-Merino Angela M
- Paule Juraj
- Paulo Octavio S
- Pena Joao Carlos
- Peres-Neto Pedro R
- Pfeiffer Vera W
- Pinho Pedro
- Piot Anthony
- Porth Ilga M
- Poulos Nicholas
- Prashad Cindy
- Puentes Adriana
- Qu Jiao
- Quintero-Vallejo Estela
- Raciti Steve M
- Raeymaekers Joost AM
- Raveala Krista M
- Rennison Diana J
- Ribeiro Milton C
- Richardson Jonathan L
- Rivas-Torres Gonzalo
- Rivera Benjamin J
- Roddy Adam B
- Rodriguez-Munoz Erika
- Roman Jose Raul
- Rossi Laura S
- Rowntree Jennifer K
- Ryan Travis J
- Salinas Santiago
- Sanders Nathan J
- Santangelo James S
- Santiago-Rosario Luis Y
- Savage Amy M
- Scheepens JF
- Schilthuizen Menno
- Schneider Adam C
- Scholier Tiffany
- Scott Jared L
- Shaheed Summer A
- Shefferson Richard P
- Shepard Caralee A
- Shykoff Jacqui A
- Silveira Georgianna
- Smith Alexis D
- Solis-Gabriel Lizet
- Soro Antonella
- Spellman Katie V
- Starke-Ottich Indra
- Stephan Jorg G
- Stephens Jessica D
- Szulc Justyna
- Szulkin Marta
- Tack Ayco JM
- Tamara Manuel E Lequerica
- Tamburrino Italo
- Tate Tayler D
- Tergemina Emmanuel
- Theodorou Panagiotis
- Thompson Ken A
- Threlfall Caragh G
- Tinghitella Robin M
- Toledo-Chelala Lilibeth
- Tong Alex T
- Tong Xin
- Uroy Lea
- Utsumi Shunsuke
- Vandegehuchte Martijn L
- VanWallendael Acer
- Vidal Paula M
- Wadgymar Susana M
- Wang Ai-Ying
- Wang Nian
- Warbrick Montana L
- Whitney Kaitlin Stack
- Whitney Kenneth D
- Wiesmeier Miriam
- Wiles J Tristian
- Wu Jianqiang
- Xirocostas Zoe A
- Yan Zhaogui
- Yao Jiahe
- Yoder Jeremy B
- Yoshida Owen
- Zhang Jingxiong
- Zhao Zhigang
- Ziter Carly D
- Zuellig Matthew P
- Zufall Rebecca A
- Zurita Juan E
- Zytynska Sharon E
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2022
- Field of study
Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale
Diminishing benefits of urban living for children and adolescents' growth and development
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abdrakhmanova Shynar
- Abdurrahmonova Zulfiya
- Abril Guadalupe Longo
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adam Ishag
- Adamczyk Marzena
- Adams Robert J.
- Adu-Afarwuah Seth
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agbor Valirie N.
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