Spectral function at high missing energies and momenta

The nuclear spectral function at high missing energies and momenta has been determined from a self-consistent calculation of the Green's function in nuclear matter using realistic nucleon-nucleon interactions. The results are compared with recent experimental data derived from ($e,e'p$) reactions on $^{12}C$. A rather good agreement is obtained if the Green's functions are calculated in a non-perturbative way.Comment: 10 pages, 3 figure

Test Beam Results of Geometry Optimized Hybrid Pixel Detectors

The Multi-Chip-Module-Deposited (MCM-D) technique has been used to build hybrid pixel detector assemblies. This paper summarises the results of an analysis of data obtained in a test beam campaign at CERN. Here, single chip hybrids made of ATLAS pixel prototype read-out electronics and special sensor tiles were used. They were prepared by the Fraunhofer Institut fuer Zuverlaessigkeit und Mikrointegration, IZM, Berlin, Germany. The sensors feature an optimized sensor geometry called equal sized bricked. This design enhances the spatial resolution for double hits in the long direction of the sensor cells.Comment: Contribution to Proceedings of Pixel2005 Workshop, Bonn Germany 200

Soft Fermi Surfaces and Breakdown of Fermi Liquid Behavior

Electron-electron interactions can induce Fermi surface deformations which break the point-group symmetry of the lattice structure of the system. In the vicinity of such a "Pomeranchuk instability" the Fermi surface is easily deformed by anisotropic perturbations, and exhibits enhanced collective fluctuations. We show that critical Fermi surface fluctuations near a d-wave Pomeranchuk instability in two dimensions lead to large anisotropic decay rates for single-particle excitations, which destroy Fermi liquid behavior over the whole surface except at the Brillouin zone diagonal.Comment: 12 pages, 2 figures, revised version as publishe

Qualification Procedures of the CMS Pixel Barrel Modules

The CMS pixel barrel system will consist of three layers built of about 800 modules. One module contains 66560 readout channels and the full pixel barrel system about 48 million channels. It is mandatory to test each channel for functionality, noise level, trimming mechanism, and bump bonding quality. Different methods to determine the bump bonding yield with electrical measurements have been developed. Measurements of several operational parameters are also included in the qualification procedure. Among them are pixel noise, gains and pedestals. Test and qualification procedures of the pixel barrel modules are described and some results are presented.Comment: 7 Pages, 7 Figures. Contribution to Pixel 2005, September 5-8, 2005, Bonn, Germna

Lepton-nucleus scattering in the impulse approximation regime

We discuss theoretical calculations of electron- and neutrino-nucleus scattering, carried out using realistic nuclear spectral functions and including the effect of final state interactions. Comparison between electron scattering data and the calculated inclusive cross sections off oxygen shows that the Fermi gas model fails to provide a satisfactory description of the measured cross sections, and inclusion of nuclear dynamics is needed. The role of Pauli blocking in charged-current neutrino induced reactions at low $Q^2$ is also analyzed.Comment: To be published in the Proceedings of NUFACT05 (Nucl. Phys. B, Proceedings Supplements

Radiation hardness of CMS pixel barrel modules

Pixel detectors are used in the innermost part of the multi purpose experiments at LHC and are therefore exposed to the highest fluences of ionising radiation, which in this part of the detectors consists mainly of charged pions. The radiation hardness of all detector components has thoroughly been tested up to the fluences expected at the LHC. In case of an LHC upgrade, the fluence will be much higher and it is not yet clear how long the present pixel modules will stay operative in such a harsh environment. The aim of this study was to establish such a limit as a benchmark for other possible detector concepts considered for the upgrade. As the sensors and the readout chip are the parts most sensitive to radiation damage, samples consisting of a small pixel sensor bump-bonded to a CMS-readout chip (PSI46V2.1) have been irradiated with positive 200 MeV pions at PSI up to 6E14 Neq and with 21 GeV protons at CERN up to 5E15 Neq. After irradiation the response of the system to beta particles from a Sr-90 source was measured to characterise the charge collection efficiency of the sensor. Radiation induced changes in the readout chip were also measured. The results show that the present pixel modules can be expected to be still operational after a fluence of 2.8E15 Neq. Samples irradiated up to 5E15 Neq still see the beta particles. However, further tests are needed to confirm whether a stable operation with high particle detection efficiency is possible after such a high fluence.Comment: Contribution to the 11th European Symposium on Semiconductor Detectors June 7-11, 2009 Wildbad Kreuth, German

SORLA regulates calpain-dependent degradation of synapsin

Introduction: Sorting-related receptor with A-type repeats (SORLA) is an intracellular sorting receptor in neurons and a major risk factor for Alzheimer disease. Methods: Here, we performed global proteome analyses in the brain of SORLA-deficient mice followed by biochemical and histopathologic studies to identify novel neuronal pathways affected by receptor dysfunction. Results: We demonstrate that the lack of SORLA results in accumulation of phosphorylated synapsins in cortex and hippocampus. We propose an underlying molecular mechanism by demonstrating that SORLA interacts with phosphorylated synapsins through 14-3-3 adaptor proteins to deliver synapsins to calpain-mediated proteolytic degradation. Discussion: Our results suggest a novel function for SORLA which is in control of synapsin degradation, potentially impacting on synaptic vesicle endocytosis and/or exocytosis

An implicit high-order material point method.

The material point method (MPM) is a version of the particle-in-cell (PIC) which has substantial advantages over pure Lagrangian or Eulerian methods in numerical simulations of problems involving large deformations. The MPM helps to avoid mesh distortion and tangling problems related to Lagrangian methods and as well as the advection errors associated with Eulerian methods. Despite the MPM being promoted for its ability to solve large deformation problems the method suffers from instabilities when material points cross between elements. These instabilities are due to the lack of smoothness of the grid basis functions used for mapping information between the material points and the background grid. In this paper a novel high-order MPM is developed to eliminate the cell-crossing instability and improve the accuracy of the MPM method

Performance of prototype BTeV silicon pixel detectors in a high energy pion beam

The silicon pixel vertex detector is a key element of the BTeV spectrometer. Sensors bump-bonded to prototype front-end devices were tested in a high energy pion beam at Fermilab. The spatial resolution and occupancies as a function of the pion incident angle were measured for various sensor-readout combinations. The data are compared with predictions from our Monte Carlo simulation and very good agreement is found.Comment: 24 pages, 20 figure

A high-precision polarimeter

We have built a polarimeter in order to measure the electron beam polarization in hall C at JLAB. Using a superconducting solenoid to drive the pure-iron target foil into saturation, and a symmetrical setup to detect the Moller electrons in coincidence, we achieve an accuracy of <1%. This sets a new standard for Moller polarimeters.Comment: 17 pages, 9 figures, submitted to N.I.