Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study

A41 Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study In: Addiction Science & Clinical Practice 2017, 12(Suppl 1): A4

Physiological effects of the amphetamines during exercise

Oxygen consumption, heart rate, minute ventilation and blood lactate were measured on two champion cyclists at work rates from 45 to 362 W (2 000 - 16 000 ft-lb / min) on a bicycle ergometer after administration of a placebo and after 10 mg of methamphetamine, without their knowledge of which was given. No differences could be detected due to the ingestion of the amphetamine in submaximum or maximum oxygen consumption, heart rate, minute ventilation or blood lactic acid. However, after the amphetamine the men were able to continue to cycle at maximum effort for a longer period and in a run to exhaustion at 90 - 95% maximum effort one man increased the time 61 % and the other 29% with marked increases in blood lactic acid. Thus the study shows that amphetamines do not increase the men's capacity for aerobic exercise. It does, however, allow them to continue to exercise at high levels of effort for a longer period and endure a higher level of anaerobic metabolism. In short-distance events this may not be dangerous but in events lasting for more Than an hour the failure to be aware of 'danger signals' and to react to them could be a threat to life as was seen in the death from 'heat-stroke' of a British champion cyclist in a 'Tour de France' some years ago

Walk or jog for health: II

No Abstract

Diagnostic, prognostic, and cost assessment of coronary artery disease in women

Women with obstructive coronary disease appear to be more challenging diagnostically and suffer a more adverse prognosis than men. More than one half of women with symptoms of ischemic heart disease have no obstructive coronary artery disease at coronary angiography, yet these women frequently have persistent symptom-related disability and consume large amounts of healthcare resources. Prior evidence has been limited regarding effective diagnostic strategies for the assessment of symptomatic women. The current report synthesizes existing evidence on diagnostic testing in women, including research from the ongoing National Heart, Lung, and Blood Institute-sponspored Women\u27s Ischemia Syndrome Evaluation (WISE) study. In addition to recent published evidence (drawn from much larger cohorts of women) that stress echocardiography and nuclear imaging are similar in their ability to risk-stratify women, the WISE study is exploring new pathophysiological mechanisms of microvascular dysfunction in women. An unfolding body of evidence suggests that as tests become more diagnostically and prognostically accurate, the process will become more cost efficient. The results from a growing number of large observational series and National Institutes of Health-sponsored studies are expected to be the foundation for cost-effective diagnostic and prognostic strategies for the approximately 5 million women who undergo evaluation for coronary disease annually