Procedimentos de Tradução no Núcleo de Aquisição de Língua de Sinais da Universidade Federal de Santa Catarina – NALS/UFSC

TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Comunicação e Expressão. Letras LibrasEste Trabalho de Conclusão de Curso apresenta uma análise histórica dos procedimentos de tradução, informações históricas do Núcleo de Aquisição de Língua de Sinais da Universidade Federal de Santa Catarina (NALS/UFSC) e alguns trabalhos desenvolvidos que trilharam os caminhos até que pudesse chegar a prática tradutória que faz parte das pesquisas desenvolvidas. Então, buscou-se trazer informações a respeito das traduções que são utilizadas como método nas pesquisas do banco de dados em aquisição da linguagem no NALS. Os materiais traduzidos no NALS são das pesquisas de sujeitos bilíngues bimodais em libras e português. E as línguas foco das traduções são a libras, língua portuguesa e língua inglesa

Management of ulcerative colitis: a clinical update

AbstractThe objective of this study was to evaluate the consensus of expert societies and published guidelines on the management of ulcerative colitis, and to compare with the experience of the authors, in order to standardize procedures that would help the reasoning and decision-making process of the physician. A search was performed in scientific literature, specifically in electronic databases: Medline/Pubmed, SciELO, EMBASE and Cochrane, and the following descriptors were used: ulcerative colitis, acute colitis, clinical treatment, surgery and randomized trial. It can be concluded that the goals of therapy in ulcerative colitis are clinical and endoscopic remission, deep, sustained remission without corticosteroids, prevention of hospitalizations and surgeries, and improved quality of life. The surgical indications are reserved for selected cases, ranging from medical intractability, complications (severe refractory acute colitis, toxic megacolon, perforation and hemorrhage) and malignancy. Information in this review article must be submitted to evaluation and criticism of the specialist responsible for the conduct to be followed, in the face of his/her reality and the clinical status of each patient.The degree of recommendation and strength of evidence were based using the GRADE system (The Grades of Recommendation, Assessment, Development, and Evaluation) described below:1. A: Experimental or observational studies of higher consistency.2. B: Experimental or observational studies of lower consistency.3. C: Case reports (non-controlled studies).4. D: Opinion without critical evaluation, based on consensus, physiological studies or animal models

Causalidade e transmissão entre os preços de mandioca, trigo, milho e seus derivados no Paraná

This study aims to analyze the relations of causality and price transmission of the cassava root, the cassava starch, the cassava flour, the wheat, the wheat flour and the corn, in the State of Parana. The used data goes from January 1995 to December 2005, with monthly regularity. It was applied the methodology of Granger causality to test the relations between the variables. The results showed long term relations between corn and cassava root prices, cassava starch and cassava flour prices, wheat and corn prices and wheat and wheat flour prices. It was emphasized the dependence of the cassava root prices in relation to corn, wheat, cassava starch and cassava flour prices and its little influence on these variables. It was also noted that cassava flour prices influenced the cassava starch prices, and the strong relation between the wheat prices and the wheat flour prices. The cassava flour and the wheat prices presented lesser dependence of the others variables. The paper concluded that there are important interrelations between the studied variables. The cassava root prices were the ones that depended most on the other variables in this study.Granger causality, Price transmission, Starch, Demand and Price Analysis,

Risks associated with a double-cropping production system – a case study in southern Brazil

This study assessed the risk exposure of the production system of a typical farm in southern Brazil. Five possible production systems were analyzed, combining three crops (soybeans, corn seasons and wheat) in different crop-year combinations, for example: “Summer soybeans followed by corn” and “Autumn corn followed by winter wheat”. Five different production systems were created based on the intensity of land use for each of the crops. Primary data were collected from a typical farm in the producing region over eight seasons (2006/07 to 2013/14). The Monte Carlo simulation technique was used to evaluate negative Net Operating Revenue (NOR) risk. The results showed that the production system with soybean and first season corn had a higher NOR and lower risk when compared with the other four production systems, which intensified the land use in the second season. When the production system had a higher rate of corn and/or wheat, the NOR and the risk to the production system increased for the first or second crop. Both corn and wheat in the second crop increased the risk to the production system on the typical farm in Cascavel, in the state of Parana (PR)

Sarcoma primário de leptomeninges: apresentação não usual e aspectos de neuroimagem previamente não descritos

Sem informação77967567

Ciclosporina A reduz a secreção de muco das vias aéreas e o transporte mucociliar de ratos

OBJETIVO: Avaliar os efeitos da ciclosporina A sobre a produção de muco das células caliciformes e sobre o transporte mucociliar in situ de ratos. MÉTODOS: Vinte e um ratos machos Wistar foram distribuídos em três grupos: Controle (n=5), Salina (n=8) e Ciclosporina A (n=8). Após 30 dias de terapia, os ratos foram mortos e os pulmões removidos da cavidade torácica. Amostras de muco foram coletadas e a medida da transportabilidade in vitro foi realizada através de um modelo de palato de rã. A velocidade do transporte mucociliar foi medida através da observação direta do deslocamento de partículas aderidas ao muco do epitélio ciliado brônquico. Por fim, efetuamos a quantificação das mucinas estocadas nas células caliciformes do epitélio respiratório. RESULTADOS: O valor médio da concentração sangüínea da ciclosporina no momento do sacrifício dos ratos foi de 1.246,57 ± 563,88 ng/ml. A transportabilidade do muco in vitro foi estatisticamente menor (p < 0.001) no grupo tratado com ciclosporina. Da mesma forma, houve um decréscimo na velocidade de transporte mucociliar nos animais imunossuprimidos em relação aos que receberam o placebo (p = 0.02). Houve diminuição significativa na quantidade de muco ácido (p = 0,01) e neutro (p = 0,02) produzidos pelas células caliciformes nos animais tratados com ciclosporina. A correlação entre a porcentagem de muco e a transportabilidade in vitro foi positiva e significante (r = 0.706, p < 0.001), assim como entre a porcentagem do muco e o transporte mucociliar in situ (r = 0.688, p = 0.001). CONCLUSÃO: O presente estudo mostra que a ciclosporina A age no sistema mucociliar causando um sério prejuízo através da redução na produção de muco ácido e neutro pelas células caliciformes como também a diminuição da velocidade de transporte mucociliar in situ e a transportabilidade do muco in vitro.PURPOSE: To assay the effects of cyclosporin A on mucus secretion from goblet cells and on mucociliary transport in situ in rats. METHODS: Twenty-one male Wistar rats were assigned to 3 groups: control (n = 5), saline (n = 8), and cyclosporin A (n = 8). After 30 days of drug therapy, the rats were killed, and the lungs were removed from the thoracic cavity. Mucus samples were collected, and the transport rate was evaluated in vitro using a bullfrog palate model. Mucociliary transport was timed in situ by direct view of particles trapped on the mucus moving across the respiratory tract. Finally, the amount of stored mucins in the goblet cells of the respiratory epithelium was measured. RESULTS: Drug dosage measurements showed that cyclosporine blood concentration at the moment the rats were killed was 1246.57 ± 563.88 ng/mL. The in vitro transport rate was significantly lower (P < .001) in the cyclosporin A-treated group. Also, the in-situ mucociliary transport rate was decreased in all cyclosporin A-treated animals when compared to the saline group (P = .02). Mucus quantity measurements showed a significant decrease on both acid (P = .01) and neutral (P = .02) mucus production from goblet cells in the animals submitted to cyclosporin A therapy. The correlation between the percentage of total mucus and in vitro transport rate was positive and significant (r = 0.706, P < .001), as was the correlation between the percentage of total mucus and the in situ mucociliary transport rate (r = 0.688, P = .001). CONCLUSION: This study shows that cyclosporin A plays an important role in the impairment of the mucociliary clearance in rats by reducing both acid and neutral mucus production from goblet cells and causing a decrease in the mucociliary transport velocity

Patients with multiple sclerosis do not necessarily consume more alcohol or tobacco than the general population

Peer reviewedPublisher PD

Efeito de reguladores de crescimento na difusão de gases e no metabolismo de maçãs 'Brookfield' em armazenamento em atmosfera controlada

The objective of this work was to evaluate the effect of growth regulators on gas diffusion and on metabolism of 'Brookfield' apple, and to determine their correlation with quality characteristics of fruit stored in controlled atmosphere. A completely randomized design was used with four replicates. After eight months of storage, the effects of water (control), aminoethoxyvinylglycine (AVG), AVG + ethephon, AVG + naphthaleneacetic acid (NAA), ethephon + NAA, sole NAA, 1‑MCP, ethylene absorption by potassium permanganate (ABS), AVG + ABS, and of AVG + 1‑MCP – applied at different rates and periods – were evaluated on: gas diffusion rate, ethylene production, respiratory rate, internal ethylene concentration, internal CO2 content, mealiness, and intercellular space. Fruit from the control and sole NAA treatments had the highest mealiness occurrence. Growth regulators significantly changed the gaseous diffusion through the pulp of 'Brookfield' apple, mainly in the treatment AVG + ABS, which kept the highest gas diffusion rate. NAA spraying in the field, with or without another growth regulator, increased ripening metabolism by rising ethylene production and respiration rate, and reduced gas diffusion during shelf life. AVG spraying cannot avoid the ethephon effect during the ripening process, and reduces both the internal space and mealiness incidence, but it is not able to induce ethylene production or to increase respiration rates.O objetivo deste trabalho foi avaliar o efeito de reguladores de crescimento na difusão de gases e no metabolismo de maçãs 'Brookfield', e determinar sua correlação com características dos frutos armazenados em atmosfera controlada. Utilizou-se o delineamento experimental inteiramente casualizado com quatro repetições. Após oito meses de armazenamento, os efeitos de água (controle), aminoetoxivinilglicina (AVG), AVG + ethephon, AVG + ácido naftalenoacético (ANA), ethephon + ANA, somente ANA, 1‑MCP, absorção de etileno por permanganato de potássio (ABS), AVG + ABS, e de AVG + 1‑MCP – aplicados em diferentes doses e épocas – foram avaliados sobre: taxa de difusão de gases, produção de etileno, taxa respiratória, concentração interna de etileno, concentração interna de CO2, polpa farinácea e espaço interno. Frutos dos tratamentos controle e ANA sozinha aprsentaram a maior ocorrência de polpa farinácea. Os reguladores de crescimento modificaram significativamente a difusão gasosa pela polpa de maçãs 'Brookfield', principalmente no tratamento AVG + ABS, que manteve a maior taxa de difusão de gases. A aplicação de ANA no campo, com ou sem outro regulador de crescimento, acelerou o metabolismo de amadurecimento, pelo aumento na produção de etileno e na taxa respiratória, e reduziu a difusão de gases durante a vida de prateleira. Aplicação de AVG não evita o efeito do ethephon durante o amadurecimento, reduz o espaço interno e a ocorrência de polpa farinácea, mas não é capaz de induzir a produção de etileno ou de aumentar a taxa respiratória