Transmission needs across a fully renewable European power system

The residual load and excess power generation of 27 European countries with a 100% penetration of variable renewable energy sources are explored in order to quantify the benefit of power transmission between countries. Estimates are based on extensive weather data, which allows for modelling of hourly mismatches between the demand and renewable generation from wind and solar photovoltaics. For separated countries, balancing is required to cover around 24% of the total annual energy consumption. This number can be reduced down to 15% once all countries are networked together with uncon- strained interconnectors. The reduction represents the maximum possible benefit of transmission for the countries. The total Net Transfer Capacity of the unconstrained interconnectors is roughly twelve times larger than current values. However, constrained interconnector capacities six times larger than the current values are found to provide 97% of the maximum possible benefit of cooperation. This motivates a detailed investigation of several constrained transmission capacity layouts to determine the export and import capabilities of countries participating in a fully renewable European electricity system

Locating the Source of Diffusion in Large-Scale Networks

How can we localize the source of diffusion in a complex network? Due to the tremendous size of many real networks--such as the Internet or the human social graph--it is usually infeasible to observe the state of all nodes in a network. We show that it is fundamentally possible to estimate the location of the source from measurements collected by sparsely-placed observers. We present a strategy that is optimal for arbitrary trees, achieving maximum probability of correct localization. We describe efficient implementations with complexity O(N^{\alpha}), where \alpha=1 for arbitrary trees, and \alpha=3 for arbitrary graphs. In the context of several case studies, we determine how localization accuracy is affected by various system parameters, including the structure of the network, the density of observers, and the number of observed cascades.Comment: To appear in Physical Review Letters. Includes pre-print of main paper, and supplementary materia

Starburst radio galaxies: general properties, evolutionary histories and triggering

In this paper we discuss the results of a programme of spectral synthesis modelling of a sample of starburst radio galaxies in the context of scenarios for the triggering of the activity and the evolution of the host galaxies. The starburst radio galaxies -- comprising ~15 - 25% of all powerful extragalactic radio sources -- frequently show disturbed morphologies at optical wavelengths, and unusual radio structures, although their stellar masses are typical of radio galaxies as a class. In terms of the characteristic ages of their young stellar populations (YSP), the objects can be divided into two groups: those with YSP ages t_ysp < 0.1 Gyr, in which the radio source has been triggered quasi-simultaneously with the main starburst episode, and those with older YSP in which the radio source has been triggered or re-triggered a significant period after the starburst episode. Combining the information on the YSP with that on the optical morphologies of the host galaxies, we deduce that the majority of the starburst radio galaxies have been triggered in galaxy mergers in which at least one of the galaxies is gas rich. However, the triggering (or re-triggering) of the radio jets can occur immediately before, around, or a significant period after the final coalescence of the merging nuclei, reflecting the complex gas infall histories of the merger events. Overall, our results provide further evidence that powerful radio jet activity can be triggered via a variety of mechanisms, including different evolutionary stages of major galaxy mergers; clearly radio-loud AGN activity is not solely associated with a particular stage of a unique type of gas accretion event.Comment: 16 pages, 3 Figures, accepted for publication in MNRA

Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin.

Huntington's disease, an inherited neurodegenerative disorder, results from abnormal polyglutamine extension in the N-terminal region of the huntingtin protein. This mutation causes preferential degeneration of striatal projection neurons. We previously demonstrated, in vitro, that dopaminergic D2 receptor stimulation acted in synergy with expanded huntingtin to increase aggregates formation and striatal death through activation of the Rho/ROCK signaling pathway. In vivo, in a lentiviral-mediated model of expanded huntingtin expression in the rat striatum, we found that the D2 antagonist haloperidol protects striatal neurons against expanded huntingtin-mediated toxicity. Two variant transcripts are generated by alternative splicing of the of D2 receptor gene, the D2R-Long and the D2R-Short, which are thought to play different functional roles. We show herein that overexpression of D2R-Short, but not D2R-Long in cell lines is associated with activation of the RhoA/ROCK signaling pathway. In striatal neurons in culture, the selective D2 agonist Quinpirole triggers phosphorylation of cofilin, a downstream effector of ROCK, which is abrogated by siRNAs that knockdown both D2R-Long and D2R-Short, but not by siRNAs targeting D2R-Long alone. Aggregate formation and neuronal death induced by expanded huntingtin, were potentiated by Quinpirole. This D2 agonist-mediated effect was selectively inhibited by the siRNA targeting both D2R-Long and D2R-Short but not D2R-Long alone. Our data provide evidence for a specific coupling of D2R-Short to the RhoA/ROCK/cofilin pathway, and its involvement in striatal vulnerability to expanded huntingtin. A new route for targeting Rho-ROCK signaling in Huntington's disease is unraveled with our findings

Identifying Nearby, Young, Late-type Stars by Means of Their Circumstellar Disks

It has recently been shown that a significant fraction of late-type members of nearby, very young associations (age <10 Myr) display excess emission at mid-IR wavelengths indicative of dusty circumstellar disks. We demonstrate that the detection of mid-IR excess emission can be utilized to identify new nearby, young, late-type stars including two definite new members ("TWA 33" and "TWA 34") of the TW Hydrae Association. Both new TWA members display mid-IR excess emission in the Wide-field Infrared Survey Explorer (WISE) catalog and they show proper motion and youthful spectroscopic characteristics -- namely H\alpha emission, strong lithium absorption, and low surface gravity features consistent with known TWA members. We also detect mid-IR excess -- the first unambiguous evidence of a dusty circumstellar disk -- around a previously identified UV-bright, young, accreting star (2M1337) that is a likely member of the Lower-Centaurus Crux region of the Scorpius Centaurus Complex.Comment: ApJ, Accepte