386 research outputs found

    L’invention de la contestation transnationale par les forums et sommets : la naissance d’un « espace public mondial » ?

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    Les manifestations de février 2003 contre la guerre en Irak soulèvent une interrogation : cette mobilisation mondiale marque-t-elle l’avènement d’un nouvel espace d’exercice de l’action publique, un espace public transnational ? Pour examiner avec rigueur un évènement qui est apparu comme une rupture, un changement d’échelle de la contestation, il convient d’en faire l’archéologie et de regarder les processus sociaux qui ont amené cette transnationalisation de la mobilisation. On a choisi de confronter la définition que donne Jürgen Habermas de l’espace public dans son ouvrage de 1962 avec l’histoire des mouvements sociaux transnationaux depuis le milieu des années 1980.The February 2003 demonstrations against the war in Iraq raised a broader question : does this global activism signal the emergence of a new transnational public sphere of collective action? To account for an event some regard as a turning point in the politics of contention, both in essence and in scale, this article undertakes an historical analysis of the social processes that have transnationalized activism. The analysis juxtaposes Jürgen Habermasâ?? definition of public space (1962) with the history of transnational social movements since the mid-1980s

    Adjustment to disease and quality of life in people with vascular Ehlers-Danlos and Loeys-Dietz syndromes : A mixed-method study

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    Vascular Ehlers-Danlos (vEDS) and Loeys-Dietz syndromes (LDS) are hereditary disorders of connective tissue having severe vascular complications (HDCTv) which lead to an increased risk of premature death. Little is known about the impact of the disease in patient's daily life. Sixteen HDCTv patients (vEDS = 9 and LDS = 7), 16 age and sex-matched hypermobile Ehlers-Danlos syndrome patients (hEDS) and 18 healthy subjects (HS), responded to self-questionnaires assessing psychosocial adjustment, quality of life (QoL), anxiety, depression, pain, fatigue and sleep problems. Patients with HDCTv were also interviewed in order to explore qualitatively their experience with the disease. Compared with HS, patients with HDCTv scored significantly higher on anxiety, depression, fatigue, sleep problems, and lower on QoL. Most HDCTv patients (93.8%) have optimal psychosocial adjustment. In addition, HDCTv patients scored higher on QoL and psychosocial adjustment, but lower in pain, fatigue, sleep problems, and depressive symptoms than hEDS patients. Four main themes were identified in qualitative analyses: living with HDCTv, knowledge/ignorance of the disease, health behaviors/self-care and coping strategies. Our results suggest that despite the negative impact of HDCTv on the patients' daily lives, overall, they present an optimal disease adjustment which points to appropriate coping strategies. More research in psychosocial aspects of people with these rare diseases are needed to confirm these results and better understand their needs

    Estimación del estado hídrico del viñedo vid a partir del contenido de agua del suelo, condiciones ambientales y desarrollo foliar

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    II Jornadas de Viticultura de la SECH 3-4 de noviembre 201

    Less is more : a comprehensive study on the effects of the unmber of gas diffusion layers on air-cathode microbial fuel cells

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    Altres ajuts: Acord transformatiu CRUE-CSICAir-cathode microbial fuel cells (AC-MFC) use a gas-diffusion-layer (GDL) coating based on polytetrafluoroethylene applied to the cathode to prevent electrolyte leakage. However, this type of GDL can also lead to a decrease in MFC performance due to electron-transfer limitation, mass-transfer limitation or catalyst availability. This study provides a comprehensive understanding of the significance of the GDL coating, demonstrating the interaction between the number of GDL coatings and the external resistance (Rext) used. An experimental design in 28 mL AC-MFCs was prepared and conducted using two different Rext (10 and 249 Ω) and four different GDL coatings (1 to 4 layers). The coating effect was not significant when operating with a high Rext, where the electron transfer was the limiting process. However, when the Rext was low, the amount of polytetrafluoroethylene limited the cathode performance due to a significant decrease in the Pt availability on the catalytic surface. Thus, GDL-1 with 10 Ω as Rext reached 0.96 mA/cm2, 3-fold higher than that obtained with 249 Ω as Rext (ca. 0.30 mA/cm2). Besides, the current density did not vary noticeably in the other cathodes with 249 Ω as Rext. Contrarily, the current density with 10 Ω as Rext decreased as the number of GDL increased (0.74, 0.57 and 0.37 for GDL-2, GDL-3 and GDL-4 respectively). These values agreed with those of the polarization curve. Furthermore, limitations were also observed in electrochemical impedance spectroscopy measurements: the charge resistance increased with the number of GDL, related to the ease of electron flow. These values were18 Ω, 22 Ω, 53 Ω and 58 Ω for GDL-1, GDL-2, GDL-3 and GDL-4, respectively, for both 10 and 249 Ω cathodes

    Comparison of ultrasound-guided versus blind interventions for supraspinatus tendinopathy : A cadaveric study

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    Background. The treatment of supraspinatus tendinopathy remains a challenge for the health professional. This study aims to analyze the precision of needle interventions in lesions of the supraspinatus tendon when conducting them in an ultrasound-guided or non-ultrasound guided (blind) manner. Methods. Study on cadaver with infiltrations performed under ultrasound control or blind after randomization of the parts and participants. Twenty fresh cadaveric shoulders and 30 practitioners with experience using musculoskeletal ultrasound and doing needle interventions. Each practitioner performed 4 ultrasound-guided and 4 unguided punctures. This provided 240 punctures that were analyzed in 3 different anatomical cuts, thus providing a database of 720 measurements for statistical analysis. Results. Statistically significant differences were observed (p<0.0001) in the distance to the bullet point between the ultrasound-guided and the non-guided infiltrations. It was estimated that the unguided punctures were performed on average 10mm farther from the bullet point than the 'ultrasound-guided' punctures. The ultrasound-guided punctures demonstrated 95% precision while the unguided punctures had a precision rate of 12.5% (p <0.0001). Conclusion. Interventions of the supraspinatus tendon should be performed in an ultrasound-guided manner to facilitate administration of the treatment in the proper area

    Mesoporous silica nanoparticles grafted with a light-responsive protein shell for highly cytotoxic antitumoral therapy

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    A novel phototriggered drug delivery nanocarrier, which exhibits very high tumor cytotoxicity against human tumoral cells, is presented. This device is based on mesoporous silica nanoparticles decorated with a biocompatible protein shell cleavable by light irradiation. The proteins that compose the protein shell (avidin, streptavidin and biotinylated transferrin) act as targeting and capping agents at the same time, avoiding the use of redundant systems. The light responsive behavior is provided by a biotinylated photocleavable cross-linker covalently grafted on the mesoporous surface, which suffers photocleavage by UV radiation (366 nm). Human tumoral cells incubated in the presence of a very low particle concentration enter into the apoptotic stage after a short irradiation time. Thus, the system described here could be applied to the treatment of exposed tumors that affect the skin, oesophagus, and stomach, among others, and are easily accessible for light irradiation

    Awareness of cognitive abilities in the execution of activities of daily living after acquired brain injury: an evaluation protocol

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    Introduction One of the main limitations that can be observed after acquired brain injury (ABI) is the alteration of the awareness of the deficits that can occur in the cognitive skills necessary for performing activities of daily living (ADL). According to the Dynamic Comprehensive Model of Awareness (DCMA), consciousness is composed of offline component, which contains the information stored about characteristics of the tasks and stable beliefs about one’s own capabilities and online awareness, which is activated in the context of the performance of a specific task. The main objective of this project was to generate and validate a detailed cognitive assessment protocol within the context of ADL to evaluate the components of DCMA. Methods and analysis The proposed protocol consists of two ecological tools: The Cog-Awareness ADL Scale to measure offline component and the Awareness ADL-task: Basic and Instrumental ADL performance-based test to measure online awareness. The aim is to identify the presence of cognitive deficits and anosognosia in patients with ABI within the context of everyday life activities. These two measures will be administered to a group of patients with ABI. In addition, these participants will complete another series of classic tests on anosognosia and cognitive functions in order to find the convergent validity of the two tests proposed in this protocol. The external validity of the Cog-Awareness ADL Scale and the relationships between awareness components within the same ADL domain will be also analysed. Ethics and dissemination This study was approved by the Ethics Committee of Biomedical Research of Andalusia, on 13 January /2017 (Proceeding 1/2017). All participants are required to provide written informed consent. The findings from this will be disseminated via scientific publication.Spanish Ministry of Economy and Competitiveness PSI2016-80331-PUniversity of MalagaUniversity of Vic - Central University of Catalonia (UVic-UCC

    Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping.

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    The laboratory mouse is the foremost mammalian model used for studying human diseases and is closely anatomically related to humans. Whilst knowledge about human anatomy has been collected throughout the history of mankind, the first comprehensive study of the mouse anatomy was published less than 60 years ago. This has been followed by the more recent publication of several books and resources on mouse anatomy. Nevertheless, to date, our understanding and knowledge of mouse anatomy is far from being at the same level as that of humans. In addition, the alignment between current mouse and human anatomy nomenclatures is far from being as developed as those existing between other species, such as domestic animals and humans. To close this gap, more in depth mouse anatomical research is needed and it will be necessary to extent and refine the current vocabulary of mouse anatomical terms
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