Controle de recalque durante a execução de edifícios no Distrito Federal.

O controle de recalque é um método de monitoramento que visa garantir e verificar o desempenho das fundações em todas as etapas de uma edificação. Esse monitoramento ainda é pouco utilizado no Distrito Federal por falta de conhecimento e também por falta de concepção da sua importância. A norma ABNT 6122/2010 - Projeto e Execuções de Fundações traz a obrigatoriedade da realização do monitoramento de recalque em edificações específicas. A revisão desta norma é de extrema importância para que haja uma mudança da cultura do Distrito Federal, dando a relevância necessária a esse controle o qual verifica o desempenho das fundações. A maneira correta de realização do monitoramento de recalque é ser realizada desde o início da obra, para que seja possível coletar os recalques em todas as fases de carregamento para que se tenha o desempenho completo da edificação. É crucial que se depreenda que o controle de recalque deve ser de natureza preventiva. Esse método é usado a fim de avaliar o desempenho das fundações, e de possibilitar um diagnóstico para uma possível intervenção o mais cedo possível visando proporcionar uma interferência mais simples e de menor custo do que se fosse diagnosticado posteriormente. Esse trabalho tem como objetivo analisar resultados de monitoramento de recalque realizados em cinquenta e três edificações em diversas áreas do Distrito Federal, e apresentar um mapeamento com recalques obtidos nessas várias áreas. Tem-se ainda o objetivo de informar a todos os empreendedores das áreas a real necessidade do monitoramento, desde o início da obra. Das cinquenta e três projeções estudadas neste trabalho em 5,66% do total foi necessário a execução de reforço, sendo em todos os casos a intervenção realizada antes da conclusão da obra, o que demostra importância preventiva do monitoramento de recalque

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species

Many infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (< 8.0 oD). Caloric intake showed a wide variation in cream content (4%), fat (4%) and energy values (559.81 Kcal/L). Staphylococcus (105/186 or 56.5%) and Enterobacter (25/186 or 13.4%) were the most prevalent genera, although other microorganisms were identified, including Klebsiella pneumoniae and Pseudomonas aeruginosa. Amoxicillin/clavulanic acid (125/157 or 79.6%), vancomycin (115/157 or 73.2%), and cephalexin (112/157 or 71.3%) were the most effective antimicrobials. High resistance rates of isolates were found to penicillin G (141/157 or 89.8%), ampicillin (135/157 or 86%), and oxacillin (118/157 or 75.2%). Multidrug resistance to ≥ 3 antimicrobials occurred in 66.2% (123/186) of the isolates. Residues of microbial multiplication inhibitory substances were found in 85% (204/240) of samples. Among the coagulase-positive-CPS and negative-CoNS staphylococci, the mecA gene was detected in 53.3% (8/15) and 75% (30/40), respectively. Genes sea, seb and sec were detected in 20% (3/15) of CPS, while tsst-1 was detected in 13.34% (2/15). In addition, 13.3% (2/15) of S. aureus were toxin-producers. Genes sea, seb and sec were detected in 90% (36/40), 5% (2/40) and 15% (6/40) CoNS, respectively. Enterotoxin production was identified in 5% (2/40) of CoNS. The identification of multidrug-resistant bacteria, staphylococci species toxin-producers harboring methicillin-resistance genes, and residues of microbial multiplication inhibitory substances reinforce the need for a continuous vigilance of milk quality offered to infant consumption by human banks

Diagnosis, Prognosis and Treatment of Canine Cutaneous and Subcutaneous Mast Cell Tumors

Mast cell tumors (MCTs) are hematopoietic neoplasms composed of mast cells. It is highly common in dogs and is extremely important in the veterinary oncology field. It represents the third most common tumor subtype, and is the most common malignant skin tumor in dogs, corresponding to 11% of skin cancer cases. The objective of this critical review was to present the report of the 2nd Consensus meeting on the Diagnosis, Prognosis, and Treatment of Canine Cutaneous and Subcutaneous Mast Cell Tumors, which was organized by the Brazilian Association of Veterinary Oncology (ABROVET) in August 2021. The most recent information on cutaneous and subcutaneous mast cell tumors in dogs is presented and discussed

REAÇÃO CRUZADA DO TESTE DE ANTÍGENO GALACTOMANANA DO HISTOPLASMA EM PACIENTE IMUNOSSUPRIMIDO TRANSPLANTADO RENAL COM PARACOCCIDIOIDOMICOSE

Introdução: Paracoccidioidomicose (PCM) e histoplasmose são micoses endêmicas na América do Sul. Ambas podem apresentar semelhanças, como adenopatias, lesões pulmonares escavadas e lesões cutâneas. O isolamento fúngico e a histopatologia ainda são os métodos padrão-ouro, porém podem causar atraso no diagnóstico, contribuindo para a morbi-mortalidade, especialmente em pacientes imunodeprimidos. Um grande avanço na investigação da histoplasmose é a detecção de antígeno urinário de Histoplasma, que permite o rápido diagnóstico com alta sensibilidade e especificidade nos casos de infecção disseminada. Reportamos aqui um paciente imunossuprimido cuja investigação inicial com antígeno urinário de Histoplasma sugeriu diagnóstico de histoplasmose disseminada, porém o diagnóstico definitivo foi PCM. Relato de caso: Um homem de 42 anos, transplantado renal em 2016 em uso de tacrolimus, micofenolato de sódio e prednisona, abriu um quadro em 2021 de lesões de pele ulceradas e evoluiu com perda ponderal, febre, linfadenopatia generalizada e rouquidão. Internado em setembro de 2022 com anemia, alteração da função renal, infiltrado pulmonar bilateral, cavitação em lobo superior esquerdo e linfonodomegalia disseminada. Nos quatro primeiros dias foram coletadas hemoculturas para fungos e micobactérias, escarro para fungos e micobactérias, biópsias de pele e linfonodo, antígeno criptocócico sérico e antígeno de Histoplasma urinário. Os primeiros resultados, disponíveis em 3 dias, foram o antígeno criptocócico sérico negativo e o antígeno de Histoplasma urinário positivo, sendo prontamente iniciado anfotericina B complexo lipídico. Após 7 dias os histopatológicos de pele e linfonodo revelaram Paracoccidioides sp., e após 42 dias as culturas de pele, linfonodo e escarro foram positivas para P brasiliensis. Houve melhora do quadro clínico e paciente recebeu alta em uso de itraconazol para acompanhamento ambulatorial. Comentários: Reação cruzada do antígeno urinário para Histoplasma com outros fungos é pouco reportada, limitada a estudos de validação do método e alguns estudos transversais. Apesar do resultado falso-positivo, o antígeno urinário para Histoplasma não deixou de ser uma importante ferramenta no caso acima reportado, pois permitiu o início rápido de anfotericina B, que trata a grande maioria dos fungos. Dessa forma, esse exame tem grande valia para pacientes com suspeita de infecção fúngica e merece ser estudado em outras micoses endêmicas

Estudo epidemiológico das dermatofitoses em cães e gatos atendidos no serviço de dermatologia da Faculdade de Medicina Veterinária e Zootecnia da UNESP - Botucatu

The objective of this study was to assess the medical records of the patients whose mycological culture of the hair in Sabouraud Dextrose Agar supplemented with chloramphenicol and cycloheximide was positive for dermathophytes, and review the cases of dermatophytosis. One hundred and thirty six medical records of patients (114 dogs and 22 cats) with dermatophytosis attended in a period of 54 months in the Veterinary Hospital of the UNESP - Botucatu were evaluated. Results obtained in this analysis have shown that the majority of the cultures were positive for Mycrosporum canis. There was no statistical difference between genders, but the number of defined breed dogs presenting dermatophytosis was higher than mongrel dogs. Among feline cases, however, there were a higher number of mongrel cats. The majority of the people and animals in contact with the patients did not report skin lesions. 32,5% of the dogs presented middle intensity itchiness, while in cats itchiness was absent in 77,3% of cases. 69,3% of the animals did not present clinical signs other than dermatological. Mean ages were 4 years in dogs and 3 years in cats. There was no statistical effect of season in the occurrence of dermatophytosis. Among animals submitted to Wood lamp evaluation, 40,9% of the dogs and 33,3% of the cats were positive for dermatophytes. Most dogs had generalized lesions, while the majority of cats presented focal lesions. The most common lesions observed were: alopecia, crusts and erythema

Epidemilogic survey of dermatophytosis in dogs and cats attended at the dermatology service of the College of Veterinary Medicine and Animal Science of UNESP - Botucatu

The objective of this study was to assess the medical records of the patients whose mycological culture of the hair in Sabouraud Dextrose Agar supplemented with chloramphenicol and cycloheximide was positive for dermathophytes, and review the cases of dermatophytosis. One hundred and thirty six medical records of patients (114 dogs and 22 cats) with dermatophytosis attended in a period of 54 months in the Veterinary Hospital of the UNESP - Botucatu were evaluated. Results obtained in this analysis have shown that the majority of the cultures were positive for Mycrosporum canis. There was no statistical difference between genders, but the number of defined breed dogs presenting dermatophytosis was higher than mongrel dogs. Among feline cases, however, there were a higher number of mongrel cats. The majority of the people and animals in contact with the patients did not report skin lesions. 32,5% of the dogs presented middle intensity itchiness, while in cats itchiness was absent in 77,3% of cases. 69,3% of the animals did not present clinical signs other than dermatological. Mean ages were 4 years in dogs and 3 years in cats. There was no statistical effect of season in the occurrence of dermatophytosis. Among animals submitted to Wood lamp evaluation, 40,9% of the dogs and 33,3% of the cats were positive for dermatophytes. Most dogs had generalized lesions, while the majority of cats presented focal lesions. The most common lesions observed were: alopecia, crusts and erythema