Quality of life and functionality in athlete and non-athlete amputees

Amputation is the total or partial ablation of a member of traumatic or surgical way resulting in physical, psychological and social harm, with considerable reduction in quality of life (QL) and functionality in everyday activities. The sporting orientation has been recommended a complementary strategy of rehabilitation and social reintegration. The aim of the study was to analyze the quality of life and functionality in athletes and non-athletes with lower limb amputation. A cross-sectional study consisting of 45 amputees, divided into two groups was carried out: sportsperson GS (n = 23) and non sportsperson GNS (n = 22). The instruments used were The Short Form Health Survey (SF-36) and the Canadian Occupational Performance Measure (COPM). For analysis of demographic data was analyzed using the chi-square test, Student’s t for parametric data and the Mann-Whitney test for nonparametric adopted significance level of p < 0.05. The GS apresented higher scores in all domains assessed by the SF-36 physical functioning (p < 0.001), role limitations due to physical health (p < 0.001), pain (p = 0.010), general health (p < 0.001), energy/fatigue (p = 0.006), social functioning (p < 0.001), role limitations due to emotional problems (p < 0.001) and emotional well-being (p < 0.001); similarly when assessed occupational performance (p < 0.001) and satisfaction in performance in daily activities (p < 0.001). Sport can reduce the restrictions of participation in daily activities contributing to increase the quality of life, developing skills for satisfactory functional performance.A amputação consiste na ablação total ou parcial de um membro, de forma traumática ou cirúrgica acarretando em danos físicos, psicológicos e sociais, com considerável redução da qualidade de vida (QV) e na funcionalidade em atividades cotidianas. A orientação esportiva tem sido recomendada como estratégia complementar a realibilitação e reintegração social. O objetivo do estudo foi analisar a qualidade de vida e a funcionalidade de adultos com amputação de membros inferiores praticantes e não praticantes de esportes. Foi realizado um estudo transversal composto por 45 amputados, divididos em dois grupos: esportista GE (n=23) e não esportista GNE (n=22). Os instrumentos utilizados foram o The Short Form Health Survey (SF-36) e a Medida Canadense de Desempenho Ocupacional (COPM). Para análise dos dados demográficos foi utilizado o teste qui-quadrado, T de Student para os dados paramétricos e de Mann-Whitney para os não paramétricos, adotado nível de significância p<0,05. O GE apresentou maiores escores em todos os domínios avaliados pelo SF-36 funcionamento físico (p<0,001), funções limitadas devido a saúde física (p<0,001), dor (p=0,010), estado geral de saúde (p<0,001), energia/fadiga (p=0,006) funcionamento social (p<0,001), funções limitadas devido a problemas emocionais (p<0,001) e bem estar emocional (p<0,001); da mesma forma quando avaliado o desempenho ocupacional (p<0,001) e a satisfação na performance nas atividades do cotidiano (p<0,001). Foi concluído que amputados praticantes de esportes apresentaram melhores níveis de qualidade de vida e capacidade funcional quando comparados a não esportistas

Study designs and statistical approaches for bilateral carpal tunnes syndrome: An overview

Background: Pathologies with bilateral involvement, such as carpal tunnel syndrome (CTS), are relatively common in clinical practice. However, some published data are misleading, as many articles consider only one hand in data analysis. Objectives: This article aims to briefly propose a study design and statistical approach for data analysis of bilateral CTS. Method: Statistical reporting. Results: Although the results of clinical and surgical interventions are usually reported by randomized clinical trials, the main guidelines do not offer recommendations on how to proceed in cases of interventions in patients with bilateral conditions. Additionally, crossover trials may be an alternative, particularly when comparing different interventions in these patients. Considering the statistical approach, traditional tests are not suitable for bilateral conditions, and result in an overestimation of the results. In contrast, regression models, mixed effects analysis, generalized estimating equations, and multilevel modeling analysis are more reliable. Furthermore, in the case of crossover trials, an ANOVA suitable for crossover design should be chosen with normally distributed data of two groups, while a variance-balanced design is the ideal choice for three or more treatments and Cochran’s Statistics. Conclusions: When considering the comparison of different therapeutic intervention/rehabilitation techniques in patients with CTS or other peripheral nerve pathologies, the choice of the most appropriate study design and statistical analysis will provide more reliable evidence

Taekwondo athletes have better postural control than handball and american football athletes / Atletas de taekwondon têm melhor controle postural do que atletas de handebol e futebol americano

Introduction: Postural control is an important prerequisite for an athlete’s performance in sport. In addition, the postural control system contributes to injury prevention. Deficits in this system can lead to body instability and overload of musculoskeletal structures generating dysfunction and pain. Objectives: The purpose of this study was to evaluate postural control in three different sports modalities: taekwondo, handball, and American football. Methods: All athletes performed a one-legged stance/balance test on a force platform in the right and left lower limbs. Three tests of thirty seconds each were performed with eyes open. The mean of the three tests was used to measure the parameters of postural control, pressure center and velocity of anteroposterior and mediolateral displacements. Results: Significant differences were observed among the three groups in all analyzed parameters (P=<0.04). Post-hoc analysis revealed that taekwondo athletes had better postural control (P=<0.035) of lower limbs compared to the other two modalities. There were no significant differences between handball and American football. Conclusion: Taekwondo athletes have better postural control during the one-legged stance/balance test than handball and American football athletes. Introdução: O controle postural é um pré-requisito importante para o desempenho do atleta no esporte. Além disso, o sistema de controle postural contribui para a prevenção de lesões. Déficits nesse sistema podem levar a instabilidade corporal e sobrecarga das estruturas musculoesqueléticas, gerando disfunção e dor. Objetivos: A proposta deste estudo foi avaliar o controle postural em três diferentes modalidades esportivas: taekwondo, handebol e futebol americano. Métodos: Todos os atletas executaram o teste de equilíbrio unipodal sobre uma plataforma de força nos membros inferiores direito e esquerdo. Foram realizados três testes de trinta segundos cada, com os olhos abertos. A média dos três testes foi utilizada para mensurar os parâmetros de controle postural, centro de pressão e velocidade dos deslocamentos anteroposteriores e mediolaterais. Resultados: Diferenças significativas foram observadas entre os três grupos em todos os parâmetros analisados (P = <0,04). A análise post hoc revelou que os atletas de taekwondo tiveram melhor controle postural (P = < 0,035) dos membros inferiores em comparação com as outras duas modalidades. Não foram observadas diferenças significativas entre o handebol e o futebol americano. Conclusão: Os atletas do taekwondo têm melhor controle postural durante o teste de equilíbrio unipodal do que os atletas do handebol e do futebol americano

The effects of low power laser irradiation on the regeneration of the common fibular nerve in rat submitted to a crush lesion.

A regeneração dos nervos periféricos é um processo natural, que demanda um período longo para se completar, havendo algumas evidências de que agentes físicos, inclusive o laser, podem acelerá-lo. O objetivo primordial deste estudo foi analisar a influência da irradiação com o laser de baixa potência (AsGaAL) sobre a regeneração nervosa, num modelo de lesão por esmagamento do nervo fibular comum de ratos. O objetivo secundário foi avaliar a concordância entre os índices funcionais do nervo fibular (PFI) e o dos nervos ciático (SFI) e tibial (TFI), segundo os métodos propostos por dois autores diferentes. Foram utilizados 35 ratos Wistar (130 dias de idade, massa corporal média de 240 gramas), divididos em quatro grupos no total, sendo três grupos de dez animais cada, conforme o procedimento realizado (1: esmagamento, sem tratamento; 2: esmagamento e tratamento simulado; 3: esmagamento e tratamento efetivo) e num grupo de cinco animais intactos, para controle. A lesão por esmagamento do nervo fibular comum foi obtida pela aplicação de uma carga de 5 Kgf por dez minutos, com uma pinça especialmente confeccionada para esse fim. A irradiação com o laser foi iniciada no primeiro dia pós-operatório, empregando um equipamento de laser AsGaAL de baixa potência (potência de 100 mW, comprimento de onda de 830 nm, dose de 140 J/cm2) de emissão contínua, pelo método transcutâneo pontual de contato, e continuada por 21 dias consecutivos. Os resultados foram avaliados pela medida da velocidade de marcha do animal e do índice funcional do fibular (PFI, de peroneal functional index). A massa corporal, a velocidade de marcha e o PFI foram medidos antes da operação e no 21º dia pós-operatório, o PFI foi obtido por meio de um programa de computador específico para esse fim, utilizando duas fórmulas diferentes. Os resultados mostraram que a massa corporal aumentou em todos os grupos, sem diferença estatística entre os períodos. A velocidade de marcha diminuiu, com diferença estatística em todos os grupos. O PFI aumentou em todos os grupos e com as duas fórmulas utilizadas na sua medida, mas no Grupo 3, embora sem diferença estatística nos períodos pré e pós-operatórios, evidenciando que a irradiação com o laser interferiu na regeneração do nervo fibular esmagado. Houve uma concordância moderada entre o PFI e o SFI, maior no período pós-operatório, demonstrando que o SFI pode ser empregado para a avaliação do nervo fibular, o que, entretanto, não é recomendável. Concluímos que a irradiação do laser de baixa potência influenciou na regeneração do nervo fibular comum esmagado de ratos, pela medida do índice funcional do fibular.Peripheral nerve regeneration is a natural process, which requires a long period to complete, with a few evidences that physical agents including laser, can speed it up. The main objective of this investigation was to analyze the influence of low power laser (AsGaAL) irradiation on nerve regeneration, in a model of crush injury of the common fibular nerve of rats. A secondary objective was to evaluate the concordance between the fibular (PFI) and sciatic (SFI) nerves functional indexes, according to the methods proposed by two different research groups. Thirty-five Wistar rats (130 days of age, 240 g average body mass) were used and divided into four groups in total, be three groups of ten animals each, according to the procedure carried out (1: crush injury, no treatment; 2: crush injury, sham irradiation; 3: crush injury, effective irradiation), and a group of five untouched animals, for normal control. The crush injury was obtained by the application of a 5 kgf load for 10 minutes, using a spring forceps especially built for this purpose. Laser irradiation was started on the first postoperative day and continued for 21 consecutive days, using a commercially available continuous emission equipment (100 mW intensity, 830 nm wave length, 140 J/cm2 dose) and the transcutaneous punctual contact method. The results were appraised for the measure of the speed of the gait of the animal and of the functional index of the fibular (PFI, de peroneal functional index). Body mass, walking speed and the functional indexes were measured before the operation and on the 21st postoperative day, the functional indexes using a specific software especially developed for this purpose and the two different methods mentioned above. The results showed that the body mass increased while speed decreased with time for all groups, but without statistical significance. The PFI increased in all groups according to the two methods of evaluation used and more markedly in Group 3, although without statistical significance, period pre and post-operative. Moderate concordance was showed between PFI and SFI, higher in the post-treatment than in the preoperative evaluation, meaning that, although not recommendable, the SFI can be used to evaluate the fibular nerve. We concludes that low power laser irradiation influence the regeneration of the crush fibular nerve of rats, as measured by the peroneal functional index

INFLUENCE OF LASER RADIATION IN NERVE REGENERATION IN DIFFERENT TREATMENT SITES

Objective: This study seeks to determine, through functional gait assessment in different irradiation sites, the influence of a low-intensity GaAsAl laser beam on an injury caused by crushing the peroneal nerve in rats. Methods: 53 rats were used, which were divided into six groups: normal, injured and untreated, injured and treated using placebo, injured and treated in the bone marrow, injured and treated in the nerve, and injured and treated in both (nerve and bone marrow). The peroneal nerve was crushed using a pair of tweezers, and subsequently treated with laser for 28 consecutive days. The functional gait evaluation analyzed the footprints, which were recorded with a video camera on an acrylic bridge in the preoperative period, and on postoperative days 14, 21 and 28, and assessed using PFI formula software. Results: In the functional gait evaluation, significant differences were found only on postoperative day 14. Conclusion: Based on the functional gait evaluation, low-intensity GaAs AI irradiation was able to accelerate and reinforce the process of peripheral nerve regeneration in rats on postoperative day 14, both in the bone marrow- and in the nerve-treated groups

Probiotic therapy reduces inflammation and improves intestinal morphology in rats with induced oral mucositis

Abstract The aim of the present study was to evaluate the effect of systemic administration of probiotics (PROB) on the progression of experimentally induced oral and intestinal mucositis in rats immunosuppressed by chemotherapy (5-fluorouracil: 5-FU). Twenty-four rats were divided into the following groups (n=6): GC (control), GPROB, G5FU and G5-FU/PROB. Groups GPROB and G5-FU/PROB received 1 g of probiotic incorporated into each 100 g of feed (Bacillus subtilis, Bifidobacterium bifidum, Enterococcus faecium and Lactobacilllus acidophilus), beginning 30 days before oral mucositis induction. Groups G5FU and G5-FU/PROB received 60 mg/kg of 5-FU on days 0 and 2. The left oral mucosa of each animal was irritated by mechanical trauma (days 1 and 2). On days 3 and 7, three animals from each group were sacrificed, and their oral mucosa and small intestine were biopsied and processed for histopathological analysis. Groups G5-FU and G5-FU/PROB showed ulcerated oral lesions at day 3, with progression in group G5-FU and regression in group G5-FU/PROB at day 7. Histologically, less severe signs of inflammation in the oral mucosa were observed in group G5-FU/PROB than in group G5-FU. Regarding the intestine, villus-related defects of lesser magnitude were observed in group G5-FU/PROB, compared with group G5-FU. Group GPROB showed greater villus height than group GC. It can be concluded that probiotic supplementation reduced oral and intestinal inflammation in immunosuppressed rats with experimentally induced mucositis, and may protect the intestine from changes induced by chemotherapy, thus contributing to overall health

ANALYSIS OF FUNCTIONAL CAPACITY IN INDIVIDUALS WITH AND WITHOUT CHRONIC LOWER BACK PAIN

<div><p>ABSTRACT Objective: The objective of this study was to analyze the functional status of adult and older adult individuals with lower back pain . Methods: Eighty-three individuals were recruited, 42 older adults (20 with lower back pain and 22 control group) and 41 younger adults (21 with lower back pain and 20 control group). Functional capacity was assessed using the following tests: Timed Up and Go (TUG), Five Times Sit-to-Stand (FTSTS), six-minute walking test (SMWT), and sitting-rising test (SRT) . Results: In the younger adults, there was no difference in functional capacity between the groups (p>0.05). On the other hand, when statistical analysis was adjusted using body mass index (BMI) as a covariate, the lower back pain group performed more poorly on the SRT (p<0.004). Furthermore, poorer physical capacity was seen in the older adults with back pain via the SRT test (p=0.001), and when the BMI was adjusted, a statistical difference was seen in the SRT as well as the SMWT (p<0.05) . Conclusion: Older individuals with lower back pain have poorer physical performance, and the sitting-rising test is the most discerning for assessment of functional status in individuals with lower back pain. Level of Evidence III, Retrospective Comparative Study.</p></div

TAEKWONDO ATHLETES HAVE BETTER POSTURAL CONTROL THAN HANDBALL AND AMERICAN FOOTBALL ATHLETES

<p></p><p>ABSTRACT Introduction: Postural control is an important prerequisite for an athlete’s performance in sport. In addition, the postural control system contributes to injury prevention. Deficits in this system can lead to body instability and overload of musculoskeletal structures generating dysfunction and pain. Objectives: The purpose of this study was to evaluate postural control in three different sports modalities: taekwondo, handball, and American football. Methods: All athletes performed a one-legged stance/balance test on a force platform in the right and left lower limbs. Three tests of thirty seconds each were performed with eyes open. The mean of the three tests was used to measure the parameters of postural control, pressure center and velocity of anteroposterior and mediolateral displacements. Results: Significant differences were observed among the three groups in all analyzed parameters (P=<0.04). Post-hoc analysis revealed that taekwondo athletes had better postural control (P=<0.035) of lower limbs compared to the other two modalities. There were no significant differences between handball and American football. Conclusion: Taekwondo athletes have better postural control during the one-legged stance/balance test than handball and American football athletes.</p><p></p