36 research outputs found

    Relativistic correlation correction to the binding energies of the ground configuration of Beryllium-like, Neon-like, Magnesium-like and Argon-like ions

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    Total electronic correlation correction to the binding energies of the isoelectronic series of Beryllium, Neon, Magnesium and Argon, are calculated in the framework of relativistic multiconfiguration Dirac-Fock method. Convergence of the correlation energies is studied as the active set of orbitals is increased. The Breit interaction is treated fully self-consistently. The final results can be used in the accurately determination of atomic masses from highly charged ions data obtained in Penning-trap experiments.Comment: version soumise 3/08/200

    Биомедицинские сигналы и изображения в цифровом здравоохранении: хранение, обработка и анализ : учебное пособие

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    В учебном пособии изложены современные практические рекомендации по математическим методам и алгоритмам анализа биомедицинских сигналов и изображений. Методы цифровой обработки биомедицинских сигналов и изображений излагаются с учетом специфических особенностей сигналов биологического происхождения и рассматриваются на конкретных примерах, иллюстрирующих их практическое применение. Основное внимание уделено работе с существующими базами данных биомедицинских сигналов, а также методикам проведения собственных функциональных исследований. Учебное пособие ориентировано на преподавателей, аспирантов и студентов‑магистрантов, обучающихся по специальностям, связанным с цифровой обработкой сигналов и изображений, интеллектуальными информационными системами и функциональной диагностикой. Пособие будет полезно также врачам, интересующимся современными методами компьютерного анализа биомедицинских сигналов и изображений и методами машинного обучения в задачах классификации данных.Работа поддержана Постановлением Правительства Российской Федерации № 211, договор 02.А03.21.0006

    Bioactivity studies and chemical profile of the antidiabetic plant Genista tenera

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    Aim of the study: Genista tenera is a plant endemic to the island of Madeira and is used in folk medicine to control diabetes. In the present work we evaluate the antihyperglycaemic activity of its n-butanol extract and determine its chromatographic profile. In addition, this extract, the ethyl acetate and diethyl ether plant extracts were studied in order to assess the plant antioxidant and acetylcholinesterase inhibitory activities, as well as its cyto- and genotoxicities. Materials and methods: HPLC-DAD-ESI-MS was used to analyze the flavonoid profile of the n-butanol extract. The antihyperglycaemic activity of this extract was performed over streptozotocin induced diabetic Wistar rats (200mg/kg, bw/day), for 15 days. Antioxidant activity (DPPH assay) and acetylcholinesterase inhibitory effect (Ellman method) were also performed. Acute cytotoxicity and genotoxicity were assessed by proliferative index quantification and the short-term chromosomal aberration technique, after exposure of lymphocytes to the extracts. Results and conclusions: The n-butanol extract, where 21 monoglycosyl and 12 diglycosyl flavonoids were detected, significantly lowered blood glucose levels, bringing them to normal values after 15 days of treatment. The best radical scavenging activity was observed for the ethyl acetate extract (48.7% at 139.1μg/mL), which was also the most effective one at the minimal concentration tested. The highest acetylcholinesterase inhibitory activity (77.0% at 70. 0μg/mL) was also obtained with the ethyl acetate extract. In vitro toxicity studies showed no evidence for acute cytotoxicity or genotoxicity. This is the first report on antidiabetic activity of genus Genista.MCES, FCT, British Council; BBSRC and Merck, Sharp & Dohm

    Computational Visualistics and Picture Morphology

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    Pictures have to be formalized digitally in an adequate manner when computer scientists are to work with them. It is mainly the relevant physical properties of the corresponding picture vehicle that have to be considered in that formalization: that is, the picture syntax. The present special issue of IMAGE deals in particular with morphological questions taking the specific, formalizing perspective of computational visualistics. It is also intended as the attempt to offer a clear and easily understandable summary of the state of the art of research on picture morphology in computational visualistics for picture scientists of the other disciplines

    Tablet PC as a PACS workstation: Observer Performance Evaluation.

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    Type 2 diabetes mellitus is a set of metabolic disorders characterized by an increase of blood glucose. The management and progression of diabetes is linked to the behaviour of the patients, since to control their blood glucose levels they must perform a regular physical activity, control diet and weight, and if necessary use medication. Today the proliferation of mobile devices has led to the existence of millions of apps relating to mhealth. Among the advantages of this type of apps is to self-management of the patient diseases. Diabetes can be controlled through the mobile devices. The main objective of this paper is to develop and evaluate the Quality of Experience (QoE) of an Android mobile app for self-controlling of patients with type 2 diabetes mellitus. A total of 50 type 2 diabetic people answered the QoE survey. Most of the questions are based on Likert scale. Most users appreciate the presented information quality. The app can help in the traditional diagnosis method, but 69% of users do not have a clear opinion
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