The Hoax

The HOAX is an examination of abusive power and lack of regulation in the homeowners' association industry; a business and quasi-government system whose key selling point is the protection of property values. The documentary follows an investigative reporter, homeowners, and HOA reform activists as they illustrate shocking evidence of financial and psychological hardships throughout Texas and Nevada. A few of these people, including the filmmaker, are the subject of adverse actions from various players in this quasi-governmental system

Implementation of Electronic Commerce in the Department of Defense and the National Aeronautics and Space Administration

President Clinton's Executive Memorandum of 26 October 1993 mandated that all Federal Government agencies implement Electronic Commerce (EC) in order to 'simplify and streamline the purchasing process.' Two agencies, the Department of Defense (DoD) and the National Aeronautics and Space Administration (NASA) employed divergent strategies and policies in implementing the President's Memorandum. The DoD pursued a strategy using an existing DoD electronic Commerce/Electronic Data Interchange (EC/EDI) architecture. The NASA employed an Internet based tool, the NASA Acquisition Internet Service (NAIS), as the cornerstone of its EC program. This thesis examines the unique approach each agency employed, analyzing organizational theory and other influential factors to explain why two Federal agencies chose to implement such different strategies.http://archive.org/details/implementationof1094531984NAU.S. Navy (U.S.N.) authorApproved for public release; distribution is unlimited

Optimal management of posterior cruciate ligament injuries: current perspectives

Background: The optimal management of posterior cruciate ligament (PCL) injuries is debated by orthopedic surgeons. A natural history study (NHS) of acute, isolated PCL tears in patients with a mean follow-up of 14.3 years was previously published. The purpose of this study was to compare and contrast the results of the NHS study with those of other studies with similar follow-up time after operative and nonoperative management of isolated PCL tears. Material and methods: With reviewing the literature, six operative management and six nonoperative management studies were found for treating isolated PCL injuries. We analyzed the subjective and objective outcomes of these 12 studies and compared them to the results of the NHS to determine optimal management of PCL injuries. Results: Final follow-up times ranged from a mean of 6.2 to 15 years in the nonoperative studies and 6.3 to 12 years in the operative studies. Side-to-side differences in laxity following surgical management ranged from 1.1 to 7 mm on KT-1000 arthrometer testing and 2.8 to 4.7 mm on Telos stress testing. Tegner scores at final follow-up ranged from 6.6 to 7.7 in nonoperative studies and 5.7 to 7.4 in operative studies. International Knee Documentation Committee scores were 73.4, 82.7, and 84 in nonoperative studies and 65 and 87 in the operative studies. Lysholm scores were 85.2 in the nonoperative study and ranged from 81 to 92.1 in operative studies. Osteoarthritis was reported with ranges from 17% to 88% in nonoperative studies and 13.3% to 63.6% in operative studies. Conclusion: We found that the subjective and objective results in the NHS compare favorably to those of outcomes for PCL reconstruction. Unless a technique is found that can completely restore knee stability, it is unlikely that simply reducing posterior laxity will improve outcomes or prevent the development of osteoarthritis

5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention: summary of key research and implications for policy and practice – Biomedical prevention

No major findings were reported at the 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2009) on currently enrolled microbicides, pre-exposure prophylaxis (PrEP) or vaccine trials, although important findings in all three areas of biomedical prevention research are expected within the next few years

Emotion perception and electrophysiological correlates in Huntington\u27s disease

Objective This study aimed to characterise, emotion perception deficits in symptomatic Huntington\u27s disease (HD) via the use of event-related potentials (ERPs). Methods ERP data were recorded during a computerised facial expression task in 11 HD participants and 11 matched controls. Expression (scrambled, neutral, happy, angry, disgust) classification accuracy and intensity were assessed. Relationships between ERP indices and clinical disease characteristics were also examined. Results Accuracy was significantly lower for HD relative to controls, due to reduced performance for neutral, angry and disgust (but not happy) faces. Intensity ratings did not differ between groups. HD participants displayed significantly reduced visual processing amplitudes extending across pre-face (P100) and face-specific (N170) processing periods, whereas subsequent emotion processing amplitudes (N250) were similar across groups. Face-specific and emotion-specific derivations of the N170 and N250 (\u27neutral minus scrambled\u27 and \u27each emotion minus neutral\u27, respectively) did not differ between groups. Conclusions Our data suggest that the facial emotion recognition performance deficits in HD are primarily related to neural degeneration underlying \u27generalised\u27 visual processing, rather than face or emotional specific processing. Significance ERPs are a useful tool to separate functionally discreet impairments in HD, and provide an important avenue for biomarker application that could more-selectively track disease progression

METHOD TO DETECT THE PRESENCE OF A MICROORGANISM OR AGENT IN AN ANIMAL

The present invention provides a method to detect the presence of a microorganism or agent in an animal. The method encompasses placement of devices at various locations where the animal resides so as to induce the animal to initiate contact with the device. As a result of this contact, the animal deposits various microorganisms and agents on the device. The device is then tested for the presence of the particular microorganism or agent of interest

The Relationship of the Characteristics of Feedlot Pens to the Percentage of Cattle Shedding \u3ci\u3eEscherichia coli\u3c/i\u3e O157:H7 Within the Pen

This study was designed to discover relationships between characteristics of feedlot pens and the percentage of cattle shedding Escherichia coli O157:H7. Twenty-nine pens from five Midwestern feedlots were each sampled once between June and September, 1999. Feces were collected from all cattle in each pen. E. coli O157:H7 was isolated from the feces of 714 of 3162 cattle tested (23%), including at least one animal from each of the 29 pens. Pen prevalence did not differ between feedyards, but did vary widely within feedyards. Muddy pens were more likely to have a higher pen prevalence than normal pens

Influence of Diet on Total and Acid Resistant \u3ci\u3eE. coli\u3c/i\u3e and Colonic pH

Nine steers were fed finishing diets in a replicated 3x3 Latin square design to determine if dietary manipulation would alter total and acid resistant E. coli populations. Manipulating diet by limit-feeding of finishing diets did not affect total or acid-resistant E. coli populations. Altering dietary ingredients did not affect total E. coli populations; however, steers fed diets containing dry-rolled or high-moisture corn had lower acid-resistant E. coli populations. Following completion of the Latin Square, all animals were fed alfalfa hay ad libitum for five days. Switching steers to alfalfa hay lowered both total and acid-resistant E. coli populations

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Uses its C-Terminus to Regulate the A2B Adenosine Receptor

CFTR is an apical membrane anion channel that regulates fluid homeostasis in many organs including the airways, colon, pancreas and sweat glands. In cystic fibrosis, CFTR dysfunction causes significant morbidity/mortality. Whilst CFTR’s function as an ion channel has been well described, its ability to regulate other proteins is less understood. We have previously shown that plasma membrane CFTR increases the surface density of the adenosine 2B receptor (A2BR), but not of the β2 adrenergic receptor (β2AR), leading to an enhanced, adenosine-induced cAMP response in the presence of CFTR. In this study, we have found that the C-terminal PDZ-domain of both A2BR and CFTR were crucial for this interaction, and that replacing the C-terminus of A2BR with that of β2AR removed this CFTR-dependency. This observation extended to intact epithelia and disruption of the actin cytoskeleton prevented A2BR-induced but not β2AR-induced airway surface liquid (ASL) secretion. We also found that CFTR expression altered the organization of the actin cytoskeleton and PDZ-binding proteins in both HEK293T cells and in well-differentiated human bronchial epithelia. Furthermore, removal of CFTR’s PDZ binding motif (ΔTRL) prevented actin rearrangement, suggesting that CFTR insertion in the plasma membrane results in local reorganization of actin, PDZ binding proteins and certain GPCRs